Free for academic non-profit institutions. Other users need a Commercial license

Aliases for UMAD1 Gene

Aliases for UMAD1 Gene

  • UBAP1-MVB12-Associated (UMA) Domain Containing 1 2 3 5
  • RPA3 Antisense RNA 1 2 3 4
  • RPA3 Opposite Strand 2 3 4
  • RPA3-AS1 3 4
  • RPA3OS 3 4
  • UBAP1-MVB12-Associated (UMA)-Domain Containing Protein 1 3

External Ids for UMAD1 Gene

Previous HGNC Symbols for UMAD1 Gene

  • RPA3-AS1
  • RPA3OS

Summaries for UMAD1 Gene

GeneCards Summary for UMAD1 Gene

UMAD1 (UBAP1-MVB12-Associated (UMA) Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UMAD1 Gene

Genomics for UMAD1 Gene

Regulatory Elements for UMAD1 Gene

Enhancers for UMAD1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around UMAD1 on UCSC Golden Path with GeneCards custom track

Promoters for UMAD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around UMAD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for UMAD1 Gene

Chromosome:
7
Start:
7,640,636 bp from pter
End:
7,968,020 bp from pter
Size:
327,385 bases
Orientation:
Plus strand

Genomic View for UMAD1 Gene

Genes around UMAD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UMAD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UMAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UMAD1 Gene

Proteins for UMAD1 Gene

  • Protein details for UMAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J7I0-UMAD1_HUMAN
    Recommended name:
    UBAP1-MVB12-associated (UMA)-domain containing protein 1
    Protein Accession:
    C9J7I0

    Protein attributes for UMAD1 Gene

    Size:
    102 amino acids
    Molecular mass:
    11180 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UMAD1 Gene

Post-translational modifications for UMAD1 Gene

No Post-translational modifications

Other Protein References for UMAD1 Gene

No data available for DME Specific Peptides for UMAD1 Gene

Domains & Families for UMAD1 Gene

Protein Domains for UMAD1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

C9J7I0

UniProtKB/Swiss-Prot:

UMAD1_HUMAN :
  • Contains 1 UMA domain.
Domain:
  • Contains 1 UMA domain.
genes like me logo Genes that share domains with UMAD1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for UMAD1 Gene

Function for UMAD1 Gene

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UMAD1 Gene

Localization for UMAD1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for UMAD1 Gene

Pathways & Interactions for UMAD1 Gene

SuperPathways for UMAD1 Gene

No Data Available

Interacting Proteins for UMAD1 Gene

Selected Interacting proteins: C9J7I0-UMAD1_HUMAN for UMAD1 Gene via IID

Symbol External ID(s) Details
TFG

Gene Ontology (GO) - Biological Process for UMAD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for UMAD1 Gene

Drugs & Compounds for UMAD1 Gene

No Compound Related Data Available

Transcripts for UMAD1 Gene

mRNA/cDNA for UMAD1 Gene

(3) REFSEQ mRNAs :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for UMAD1 Gene

No ASD Table

Relevant External Links for UMAD1 Gene

GeneLoc Exon Structure for
UMAD1
ECgene alternative splicing isoforms for
UMAD1

Expression for UMAD1 Gene

mRNA expression in normal human tissues for UMAD1 Gene

NURSA nuclear receptor signaling pathways regulating expression of UMAD1 Gene:

UMAD1
genes like me logo Genes that share expression patterns with UMAD1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for UMAD1 Gene

Orthologs for UMAD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for UMAD1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RPA3-AS1 35
  • 58 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RPA3-AS1 35
  • 62 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm16039 35
  • 48 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RPA3-AS1 35
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves RPA3-AS1 35
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RPA3-AS1 35
  • 63 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:dkey-119m17.2 35
  • 24 (a)
OneToOne
Species where no ortholog for UMAD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UMAD1 Gene

ENSEMBL:
Gene Tree for UMAD1 (if available)
TreeFam:
Gene Tree for UMAD1 (if available)

Paralogs for UMAD1 Gene

No data available for Paralogs for UMAD1 Gene

Variants for UMAD1 Gene

Sequence variations from dbSNP and Humsavar for UMAD1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs2159830 -- 7,866,894(+) CATTC(A/C)AGGAA intron-variant
rs2159831 -- 7,879,647(+) ATAAA(C/T)AAATG downstream-variant-500B
rs2160139 -- 7,755,659(+) GCATT(A/G)AAAGT intron-variant
rs2194656 -- 7,819,571(+) CGTGT(A/G)TATTA intron-variant
rs2194657 -- 7,819,617(+) AAACC(A/G)GTGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UMAD1 Gene

Variant ID Type Subtype PubMed ID
dgv128n17 CNV loss 16327808
dgv6249n100 CNV gain 25217958
esv1554962 CNV insertion 17803354
esv1736638 CNV insertion 17803354
esv2673859 CNV deletion 23128226
esv2733939 CNV deletion 23290073
esv2752174 CNV gain 17911159
esv2752177 CNV gain 17911159
esv2761144 CNV gain+loss 21179565
esv3307777 CNV mobile element insertion 20981092
esv3443276 CNV insertion 20981092
esv3612094 CNV loss 21293372
esv3891036 CNV gain 25118596
esv3891038 CNV gain 25118596
esv3891039 CNV loss 25118596
nsv1027123 CNV loss 25217958
nsv1030180 CNV loss 25217958
nsv1034199 CNV loss 25217958
nsv1073637 CNV deletion 25765185
nsv365823 CNV deletion 16902084
nsv464304 CNV gain 19166990
nsv518177 CNV loss 19592680
nsv523479 CNV gain 19592680
nsv523540 CNV loss 19592680
nsv606042 CNV gain 21841781
nsv606044 CNV gain 21841781
nsv606045 CNV loss 21841781
nsv606046 CNV gain 21841781
nsv8043 CNV gain 18304495
nsv818476 CNV gain 17921354
nsv950809 CNV duplication 24416366
nsv970790 CNV duplication 23825009

Variation tolerance for UMAD1 Gene

Gene Damage Index Score: 0.69; 14.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for UMAD1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UMAD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UMAD1 Gene

Disorders for UMAD1 Gene

Relevant External Links for UMAD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UMAD1

No disorders were found for UMAD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UMAD1 Gene

Publications for UMAD1 Gene

  1. UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes. (PMID: 20448139) de Souza R.F. … Aravind L. (Bioinformatics 2010) 2 3 65
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  3. Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries. (PMID: 24556642) Zeng Z. … Shaffer J.R. (Caries Res. 2014) 3 65
  4. Genome-wide association study of serious blistering skin rash caused by drugs. (PMID: 21221126) Shen Y. … Pe'er I. (Pharmacogenomics J. 2012) 3 65
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 65

Products for UMAD1 Gene

Sources for UMAD1 Gene

Content