ULK2 Gene
protein-coding GIFtS : 62 GCID: GC17 M019674
Unc-51 Like Autophagy Activating Kinase 2 unc-51 (C. elegans)-like kinase 2, unc-51-like kinase 2...
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Aliasesfor ULK2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases Unc-51 Like Autophagy Activating Kinase 2 1 2 Unc51.22 EC 2.7.11.13 8 Serine/Threonine-Protein Kinase ULK22 Unc-51 (C. Elegans)-Like Kinase 21 KIAA06233 Unc-51-Like Kinase 2 (C. Elegans)1 Unc-51-Like Kinase 23 ATG1B2 EC 2.7.118
Export aliases for ULK2 gene to outside databases Previous GC identifers: GC17M019848 GC17M021314 GC17M019578 GC17M019836 GC17M019839 GC17M019614 GC17M019053
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Summariesfor ULK2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ULK2 Gene: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. (provided by RefSeq, Dec 2008) GeneCards Summary for ULK2 Gene: ULK2 (unc-51 like autophagy activating kinase 2) is a protein-coding gene. Diseases associated with ULK2 include smith magenis syndrome alcoholism related super-pathways are Transcription Receptor-mediated HIF regulation and mTOR signalling . GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding . An important paralog of this gene is PDIK1L . UniProtKB/Swiss-Prot: ULK2_HUMAN, Q8IYT8 Function : Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream ofphosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons
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Genomic Viewsfor ULK2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000017.10 NC_018928.2 NT_010718.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ULK2 gene promoter:ER-alpha Elk-1 AP-2alpha isoform 2 NF-AT NF-AT4 NF-AT2 NF-AT3 AP-2alpha isoform 4 AP-2alpha NF-AT1 Other transcription factors Search SABiosciences Chromatin IP Primers for ULK2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2 ULK2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17M019674: view genomic region
(about GC identifiers )
Start: 19,674,142 bp from pter End:
19,771,249 bp from pter
Size: 97,108 bases Orientation:
minus strand
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Proteinsfor ULK2 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: ULK2_HUMAN, Q8IYT8 See
protein sequence )Recommended Name: Size : 1036 amino acids; 112694 DaSubunit : Interacts with SYNGAP1 (By similarity). Component of a complex consisting of ATG13/KIAA0652, ULK1 andRB1CC1/FIP200. Interacts (via C-terminus) with ATG13/KIAA0652. Associates with the mammalian target of rapamycin complex 1 (mTORC1) through an interaction with RPTOR
Subcellular location : Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Localizes to pre-autophagosomalmembrane
Sequence caution : Sequence=BAA31598.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;Secondary accessions : A8MY69 O75119Explore the universe of human proteins at neXtProt for ULK2: NX_Q8IYT8 Explore proteomics data for ULK2 at MOPED Post-translational modifications:
UniProtKB: Autophosphorylated. In response to nutrient limitation, probably phosphorylated and activated by AMPK, leading to activate autophagy
View modification sites using PhosphoSitePlus View neXtProt modification sites for NX_Q8IYT8 4/5 DME Specific Peptides for ULK2 (Q8IYT8 ) (see all 5 )ULK2 Protein expression data from MOPED1 2 3 : About this image REFSEQ proteins (2 alternative transcripts): NP_001136082.1 NP_055498.3 ENSEMBL proteins: ENSP00000354877 ENSP00000378914 ENSP00000464892 ENSP00000465666 ENSP00000467277 Human Recombinant Protein Products for ULK2: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing ULK2 Antibody Products: Assay Products for ULK2:
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Protein
Domains /for ULK2 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section IUPHAR Guide to PHARMACOLOGY protein family classification: unc-51-like kinase 2 (C. elegans) Unc-51-like kinase (ULK) family 5/7 InterPro protein domains (see all 7 ):
Graphical View of Domain Structure for InterPro Entry Q8IYT8 ProtoNet protein and cluster: Q8IYT8
UniProtKB/Swiss-Prot: ULK2_HUMAN, Q8IYT8 Domain : The CTD-like region mediates membrane-binding and incorporation into large protein complexesSimilarity : Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamilySimilarity : Contains 1 protein kinase domainAbout GeneDecksing
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Functionfor ULK2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: ULK2_HUMAN, Q8IYT8 Function : Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream ofphosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons Catalytic activity : ATP + a protein = ADP + a phosphoprotein Enzyme Numbers (IUBMB): EC 2.7.11.1 1 2 EC 2.7.11 2
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8 ): About this table
About GeneDecksing Phenotypes: 7 GenomeRNAi human phenotypes for ULK2 :4 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Ulk2) :About GeneDecksing Animal Models: Ulk2 tm1Lex Ulk2 tm1.1Thsn In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ULK2
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Pathways & Interactionsfor ULK2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for ULK2 About See pathways by source SuperPath Contained pathways About 1 Translation Insulin regulation of translation 2 Energy dependent regulation of mTOR by LKB1-AMPK 3 Regulation of autophagy
Pathways by source See SuperPaths Show all pathways 1 2 (Kegg details for ULK2) :About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ULK2 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/372 Interacting proteins for ULK2 (Q8IYT8 2 , 3 ENSP00000354877 4 via UniProtKB, MINT, STRING , and/or I2D (see all 372 )About this table Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10 ): About this table
About GeneDecksing
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Drugs & Compoundsfor ULK2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
IUPHAR ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ULK2 2 HMDB Compounds for ULK2 About this table ULK2
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Transcriptsfor ULK2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ULK2 gene (2 alternative transcripts): NM_001142610.1 NM_014683.3 Unigene Cluster for ULK2:
Unc-51-like kinase 2 (C. elegans) Hs.168762 [show with all ESTs ] Unigene Representative Sequence: NM_014683 11 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000570983 ENST00000361658 (uc002gwm.4 ) ENST00000395544 (uc002gwn.3 )ENST00000571454 ENST00000575432 ENST00000571137 ENST00000580130 ENST00000574854 ENST00000571177 ENST00000574732 ENST00000580118 Primer ULK2 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
Additional mRNA sequence: AB014523.1 AK098316.1 AK314345.1 AL080134.1 BC034988.1 BC039310.1
12 DOTS entries : DT.442064 DT.95254360
DT.95300638 DT.100820269 DT.409255 DT.95162245 DT.100820265 DT.100820264 DT.100820267 DT.121009378 DT.92009029 DT.102825975 24/176 AceView cDNA sequences (see all 176 ):
AA743663 BM717560 AA765145 AL045472 AA331534 CR591285 AL044752 CR613562 F05878 T16293 BX440574 AA858045 CB321831 W01096 CB851547 AA418868 AA504115 CD251854 Z45674 BM556218 D57833 BX089406 AI207179 BC039310 GeneLoc Exon Structure 5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ULK2 (see all 11 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b ^ 15a · 15b · 15c ^ 16a · 16b · 16c ^ SP1 : SP2 : - SP3 : - - SP4 : - - SP5 : -
ExUns: 17 ^ 18a · 18b ^ 19 ^ 20 SP1 : SP2 : SP3 : SP4 : SP5 :
ECgene alternative splicing isoforms for ULK2
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Expression for ULK2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ULK2 expression in normal human tissues
(normalized intensities) ULK2 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
ULK2 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells Database 5/6 selected tissues (see all 6 ) fully expand See ULK2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ULK2 SOURCE GeneReport for Unigene cluster: Hs.168762 SABiosciences Expression via Pathway-Focused PCR Arrays including ULK2 : Primer ULK2 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ULK2
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Orthologsfor ULK2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for ULK2 gene from 7/16 species (see all 16 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Ulk21 5
Unc-51 like kinase 2 (C. elegans)5 1
90.48(n) 1 93.73(a) 1
11 (37.96 cM) 5 29869 1 NM_013881.4 1 NP_038909.3 1 61775649 5
chicken Aves ULK21
unc-51-like kinase 2 (C. elegans)
79.25(n) 86.68(a)
417614 XM_415858.3 XP_415858.3
lizard Reptilia ULK26
Uncharacterized protein
66(a)
1 ↔ 1
GL344046.1(30105-80192)
African clawed frog Amphibia Xl.80482
Xenopus laevis transcribed sequence with moderate similarity more
80.83(n)
BG731037.1
zebrafish Actinopterygii Dr.162982
Transcribed sequence with weak similarity to protein more
76.96(n)
CK238267.1
fruit fly Insecta CG88663 1
protein amino acid phosphorylation protein3 1
37(a) 3 50.05(n) 1 45.21(a) 1
85D113 39454 1 NM_140344.2 1 NP_648601.1 1
worm Secernentea unc-511 3
serine/threonine protein kinase3 1
46(a) 3 49.27(n) 1 44.51(a) 1
V(19988350-19996523)3 180311 1 NM_075468.3 1 NP_507869.1 1
ENSEMBL Gene Tree for ULK2 (if available)TreeFam Gene Tree for ULK2 (if available)
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Paralogsfor ULK2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ULK2 gene PDIK1L 2 ULK1 2 ULK3 2 STK35 2 18/30 SIMAP similar genes for ULK2 using alignment to 4 protein entries: ULK2_HUMAN (see all proteins )
(see all similar genes ):MARK4 UBIAD1 CAMK1G ULK3 DKFZp564L2416 KIAA0999 NEK6 PRKAA1 NUAK1 NF2 ULK1 PRKACB KIN27 PRKD2 RPS6KA2 SGK2 PNCK RPS6KA3 About GeneDecksing
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Genomic Variantsfor ULK2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 17 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for ULK2 (19674142 - 19771249 bp)
Structural Variations Database of Genomic Variants (DGV) 5 variations for ULK2 : About this table SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor ULK2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 608650
OMIM disorders : --3 : About MalaCards smith magenis syndrome alcoholism neuronitis Genetic Association Database (GAD): ULK2 Human Genome Epidemiology (HuGE) Navigator: ULK2 (2 documents) Export disorders for ULK2 gene to outside databases
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Publicationsfor ULK2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ULK2 gene, integrated from 9 sources (see all 27 ):(articles sorted by number of sources associating them with ULK2) Utopia : connect your pdf to the dynamic
Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains. (PubMed id 10557072) 1 , 3, 9(1999) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 , 4(2010) Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. (PubMed id 18936157) 1 , 2 (2009) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811) 1 , 2 (1998) Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606) 1 (2012) ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs. (PubMed id 23043107) 1 (2012) ULK1 inhibits the kinase activity of mTORC1 and cell proliferation. (PubMed id 21795849) 2 (2011) The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy. (PubMed id 21460635) 2 (2011) Ammonia-induced autophagy is independent of ULK1/ULK2 kinases. (PubMed id 21690395) 2 (2011)
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Specialized Databases showing ULK2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for ULK2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ULK2 gene: ULK2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ULK2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ULK2 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for ULK2
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ULK2
ThermoFisher Antibody for ULK2
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ULK2
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