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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ULBP3 Gene

protein-coding   GIFtS: 56
GCID: GC06M150477

UL16 Binding Protein 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
UL16 Binding Protein 31 2     RAET1N2 3
Retinoic Acid Early Transcript 1N2 3     NKG2D Ligand 32
ALCAN-gamma2 3     UL16-Binding Protein 32
N2DL-32 3     N2DL33
NKG2DL32 3     

External Ids:    HGNC: 148951   Entrez Gene: 794652   Ensembl: ENSG000001310197   OMIM: 6056995   UniProtKB: Q9BZM43   

Export aliases for ULBP3 gene to outside databases

Previous GC identifers: GC06M149946 GC06M150281 GC06M150416 GC06M147951


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ULBP3 Gene: 
ULBP3 (UL16 binding protein 3) is a protein-coding gene. Diseases associated with ULBP3 include alopecia areata, and alopecia, and among its related super-pathways are Immune System and Immune response Role of DAP12 receptors in NK cells. GO annotations related to this gene include MHC class I receptor activity. An important paralog of this gene is ULBP1.

UniProtKB/Swiss-Prot: N2DL3_HUMAN, Q9BZM4
Function: Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling
pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands
to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal
transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling
responses than does ULBP2 or ULBP1

Gene Wiki entry for ULBP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_025741.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ULBP3 gene promoter:
         USF1   USF2   FOXD3   USF-1:USF-2   Evi-1   MEF-2A   USF-1   Sox9   aMEF-2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidULBP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ULBP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ULBP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25   Ensembl cytogenetic band:  6q25.1   HGNC cytogenetic band: 6q25

ULBP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ULBP3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M150477:  view genomic region     (about GC identifiers)

Start:
150,384,286 bp from pter      End:
150,390,231 bp from pter
Size:
5,946 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: N2DL3_HUMAN, Q9BZM4 (See protein sequence)
Recommended Name: NKG2D ligand 3 precursor  
Size: 244 amino acids; 27949 Da
Subunit: Does not bind to beta2-microglobulin. Interacts with human cytomegalovirus/HHV-5 protein UL142
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor
Miscellaneous: The ULBPs are unusual members of the extended MHC class I superfamily, because they do not contain
the alpha 3 domain and they lack a transmembrane domain. They are unlikely to present peptides
Miscellaneous: The region from chromosome 6q24.1-6q25.3 contains as many as 10 ULBP-related sequences, many of
which are pseudogenes
1 PDB 3D structure from and Proteopedia for ULBP3:
1KCG (3D)    
Secondary accessions: Q5VY82 Q8IZX5 Q8TE75

Explore the universe of human proteins at neXtProt for ULBP3: NX_Q9BZM4

Explore proteomics data for ULBP3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BZM4

  • ULBP3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ULBP3 Protein Expression
    REFSEQ proteins: NP_078794.1  
    ENSEMBL proteins: 
     ENSP00000356308   ENSP00000403562  
    Reactome Protein details: Q9BZM4
    Human Recombinant Protein Products for ULBP3: 
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    Cloud-Clone Corp. Proteins for ULBP3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0042612MHC class I protein complex ----
    GO:0046658anchored to plasma membrane IDA11239445

    ULBP3 for ontologies           About GeneDecksing



    ULBP3 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for ULBP3 

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    Cloud-Clone Corp. ELISAs for ULBP3 
    Cloud-Clone Corp. CLIAs for ULBP3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR011161 MHC_I-like_Ag-recog
     IPR011162 MHC_I/II-like_Ag-recog
     IPR001039 MHC_I_a_a1/a2

    Graphical View of Domain Structure for InterPro Entry Q9BZM4

    ProtoNet protein and cluster: Q9BZM4

    1 Blocks protein domain: IPB001039 MHC class I signature

    UniProtKB/Swiss-Prot: N2DL3_HUMAN, Q9BZM4
    Similarity: Belongs to the MHC class I family


    ULBP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: N2DL3_HUMAN, Q9BZM4
    Function: Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling
    pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands
    to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal
    transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling
    responses than does ULBP2 or ULBP1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003823antigen binding IBA--
    GO:0046703natural killer cell lectin-like receptor binding IDA11239445
         
    ULBP3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ULBP3 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ULBP3 
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    miRNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ULBP3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Immune System
    Immune System0.56
    Adaptive Immune System0.56
    2Immune response Fc epsilon RI pathway
    Natural killer cell mediated cytotoxicity0.31
    3Classical antibody-mediated complement activation
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for ULBP3
        Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
    Adaptive Immune System
    Immune System


    1         Kegg Pathway  (Kegg details for ULBP3):
        Natural killer cell mediated cytotoxicity


    ULBP3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ULBP3

    1 Interacting protein for ULBP3 (Q9BZM43) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KLRK1P267183I2D: score=3 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response ----
    GO:0019048modulation by virus of host morphology or physiology IEA--
    GO:0019882antigen processing and presentation IBA--
    GO:0030101natural killer cell activation IDA11239445
    GO:0042267natural killer cell mediated cytotoxicity IDA11239445

    ULBP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ULBP3 (N2DL3)

    1 HMDB Compound for ULBP3    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about ULBP3 / N2DL3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ULBP3 gene: 
    NM_024518.1  

    Unigene Cluster for ULBP3:

    UL16 binding protein 3
    Hs.326556  [show with all ESTs]
    Unigene Representative Sequence: AK297815
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367339(uc011eej.1 uc003qns.3 uc011eek.1) ENST00000438272

    miRNA
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    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ULBP3
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    GenScript: all cDNA clones in your preferred vector: ULBP3 (NM_024518)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ULBP3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ULBP3
    Sirion Biotech Customized lentivirus for stable overexpression of ULBP3 
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ULBP3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ULBP3

    Additional mRNA sequence: 

    AB052908.1 AF304379.1 AF346596.1 AK297815.1 AK302076.1 AK315275.1 AY027538.1 BC098127.1 

    2 DOTS entries:

    DT.75195179  DT.428295 

    8 AceView cDNA sequences:

    AB052908 AY027538 AI091180 BP364885 AF304379 NM_024518 AF346596 BF844817 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ULBP3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5
    SP1:              -                           
    SP2:                                          


    ECgene alternative splicing isoforms for ULBP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ULBP3 expression in normal human tissues (normalized intensities)      ULBP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGGCAAAT
    ULBP3 Expression
    About this image


    ULBP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             Cumulus Cells Antral Follicle
     
     Adipose (Muscoskeletal System)
             Mesenchymal Stem Cells Subcutaneous White Adipose
     
     Uterus (Reproductive System)
             endometrial endothelial cell   

    See ULBP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ULBP3

    SOURCE GeneReport for Unigene cluster: Hs.326556
        SABiosciences Custom PCR Arrays for ULBP3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ULBP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of mammals.

    Orthologs for ULBP3 gene from 1/2 species (see all 2)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    cow
    (Bos taurus)
    Mammalia --
    --
    (see all 12)
    Uncharacterized protein
    (see all 12)
    56(a)
    47(a)
    (see all 12)
    many → 1
    many → 1
    (see all 12)
    9(88244953-88245726)
    9(88249142-88250182)


    ENSEMBL Gene Tree for ULBP3 (if available)
    TreeFam Gene Tree for ULBP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ULBP3 gene
    ULBP12  RAET1G2  RAET1L2  RAET1E2  ULBP22  
    9 SIMAP similar genes for ULBP3 using alignment to 1 protein entry:     N2DL3_HUMAN:
    RAET1H    RAET1L    ULBP1    RAET1G    ULBP2    RAET-1E
    RAET1E    HLA-B    HLA-A

    ULBP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/216 SNPs in ULBP3 are shown (see all 216)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1831325901,2
    --150385258(+) CCCCTC/TGTCCT 1 -- ds50010--------
    rs1869247241,2
    --150385259(+) CCCTCA/GTCCTG 1 -- ds50010--------
    rs1172921541,2
    C,F--150385297(+) GCCTCC/TTCCAG 1 -- ds50011Minor allele frequency- T:0.01NA 120
    rs1509953231,2
    --150385431(+) AACCTA/GCTGTG 1 -- ds50010--------
    rs20102591,2
    C,F,O,A,H--150385475(-) GGGCCG/AGTTGA 1 -- ds500124Minor allele frequency- A:0.31NS EA NA WA 4032
    rs126620671,2
    C,F,H--150385476(+) CAACCG/AGCCCT 1 -- ds50018Minor allele frequency- A:0.10NS WA NA CSA EA 484
    rs1408303851,2
    --150385577(+) CAGGCA/GACACC 1 -- ds50010--------
    rs759312841,2
    C,F--150385618(+) GAGAAG/AGTCCC 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs48698151,2
    C,F,A--150385670(+) TTCCTC/TCCACC 1 -- ds5001 trp35Minor allele frequency- T:0.20WA NA CSA 243
    rs2017384151,2
    --150385714(+) TGCCCA/TCAGTA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for ULBP3 (150384286 - 150390231 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for ULBP3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2678333CNV Deletion23128226
    esv2732878CNV Deletion23290073
    esv2664929CNV Deletion23128226
    nsv886764CNV Loss21882294
    esv7375CNV Loss19470904
    nsv886767CNV Gain21882294
    nsv517022CNV Gain+Loss19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ULBP3
    DNA2.0 Custom Variant and Variant Library Synthesis for ULBP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605699    OMIM disorders: --

    10 diseases for ULBP3:    About MalaCards
    alopecia areata    alopecia    nasopharyngitis    malignant glioma
    acute myeloid leukemia    chronic lymphocytic leukemia    myeloid leukemia    hepatitis b
    leukemia    hepatitis

    1 disease from the University of Copenhagen DISEASES database for ULBP3:
    Alopecia areata

    ULBP3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ULBP3
    Human Genome Epidemiology (HuGE) Navigator: ULBP3 (5 documents)

    Export disorders for ULBP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ULBP3 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with ULBP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3. (PubMed id 11827464)1, 2, 3 Radosavljevic M.... Bahram S. (2002)
    2. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. (PubMed id 11239445)1, 2, 3 Cosman D.... Chalupny N.J. (2001)
    3. Polymorphisms of NKG2D ligands: diverse RAET1/ULBP ge nes in northeastern Thais. (PubMed id 19688209)1, 4, 9 Romphruk A.V....Leelayuwat C. (2009)
    4. Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evi dence of diversity between human populations. (PubMed id 20219610)1, 4, 9 Antoun A....Briggs D.C. (2010)
    5. Genome-wide association study in alopecia areata impl icates both innate and adaptive immunity. (PubMed id 20596022)1, 4 Petukhova L....Christiano A.M. (2010)
    6. Intracellular sequestration of the NKG2D ligand ULBP3 by human cytomegalovirus. (PubMed id 20530255)1, 2 Bennett N.J....Wills M.R. (2010)
    7. NKG2D ligands: unconventional MHC class I-like molecules exploited by viruses and cancer. (PubMed id 12753652)1, 2 Cerwenka A. and Lanier L.L. (2003)
    8. Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3. (PubMed id 11754823)1, 2 Radaev S.... Sun P.D. (2001)
    9. Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. (PubMed id 11491531)1, 2 Steinle A....Spies T. (2001)
    10. [Expression of NKG2D ligands on dendritic cells at different development stages and its effect on cytotoxicity of NK cells.] (PubMed id 18394338)1, 9 Tu S.F....Sun M. (2008)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79465 HGNC: 14895 AceView: ULBP3 Ensembl:ENSG00000131019 euGenes: HUgn79465
    ECgene: ULBP3 Kegg: 79465 H-InvDB: ULBP3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for ULBP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for ULBP3 gene:
    Search GeneIP for patents involving ULBP3

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