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ULBP2 Gene

protein-coding   GIFtS: 59
GCID: GC06P150263

UL16 Binding Protein 2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UL16 Binding Protein 21 2     NKG2DL22 3
Retinoic Acid Early Transcript 1H2 3     RAET1H2 3
ALCAN-alpha2 3     UL16-Binding Protein 22 3
N2DL-22 3     NKG2D Ligand 22
N2DL22 3     Retinoic Acid Early Transcript 1 H2

External Ids:    HGNC: 148941   Entrez Gene: 803282   Ensembl: ENSG000001310157   OMIM: 6056985   UniProtKB: Q9BZM53   

Export aliases for ULBP2 gene to outside databases

Previous GC identifers: GC06P149824 GC06P150158 GC06P150294 GC06P150355 GC06P150304 GC06P147828


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ULBP2 Gene:
ULBP2 (UL16 binding protein 2) is a protein-coding gene. Diseases associated with ULBP2 include mhc class i deficiency, and cytomegalovirus infection. GO annotations related to this gene include antigen binding and natural killer cell lectin-like receptor binding. An important paralog of this gene is ULBP1.

UniProtKB/Swiss-Prot: N2DL2_HUMAN, Q9BZM5
Function: Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling
pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands
to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal
transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with
UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might
escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does
not reach the cell surface

Gene Wiki entry for ULBP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ULBP2 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 4   AP-2alpha isoform 2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidULBP2 promoter sequence
   Search Chromatin IP Primers for ULBP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ULBP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25   Ensembl cytogenetic band:  6q25.1   HGNC cytogenetic band: 6q25

ULBP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ULBP2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P150263:  view genomic region     (about GC identifiers)

Start:
150,263,136 bp from pter      End:
150,270,371 bp from pter
Size:
7,236 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: N2DL2_HUMAN, Q9BZM5 (See protein sequence)
Recommended Name: NKG2D ligand 2 precursor  
Size: 246 amino acids; 27368 Da
Subunit: Interacts with the CMV glycoprotein UL16. Does not bind to beta2-microglobulin
Miscellaneous: The ULBPs are unusual members of the extended MHC class I superfamily, because they do not contain
the alpha 3 domain and they lack a transmembrane domain. They are unlikely to present peptides
Secondary accessions: Q5VUN4

Explore the universe of human proteins at neXtProt for ULBP2: NX_Q9BZM5

Explore proteomics data for ULBP2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn68, Asn82

  • See ULBP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079493.1  
    ENSEMBL proteins: 
     ENSP00000356320  

    ULBP2 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for ULBP2

    ULBP2 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011162 MHC_I/II-like_Ag-recog
     IPR011161 MHC_I-like_Ag-recog
     IPR001039 MHC_I_a_a1/a2

    Graphical View of Domain Structure for InterPro Entry Q9BZM5

    ProtoNet protein and cluster: Q9BZM5

    1 Blocks protein domain: IPB001039 MHC class I signature

    UniProtKB/Swiss-Prot: N2DL2_HUMAN, Q9BZM5
    Similarity: Belongs to the MHC class I family


    ULBP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: N2DL2_HUMAN, Q9BZM5
    Function: Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling
    pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands
    to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal
    transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with
    UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might
    escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does
    not reach the cell surface

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003823antigen binding IBA--
    GO:0046703natural killer cell lectin-like receptor binding IDA11239445
         
    ULBP2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ULBP2:
     Decreased cell number, increas  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ULBP2
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    miRNA
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    hsa-mir-34c-5p (MIRT006287), hsa-mir-34a-5p (MIRT006286)

    Block miRNA regulation of human, mouse, rat ULBP2 using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    N2DL2_HUMAN, Q9BZM5: Cell membrane; Lipid-anchor, GPI-anchor. Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane5
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA18676862
    GO:0009986cell surface IDA18676862
    GO:0046658anchored component of plasma membrane IDA11239445

    ULBP2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ULBP2 About    
    See pathways by source

    SuperPathContained pathways About
    1Immune response Role of DAP12 receptors in NK cells
    Natural killer cell mediated cytotoxicity0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for ULBP2):
        Natural killer cell mediated cytotoxicity


    ULBP2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ULBP2
    Interactions:

        Search GeneGlobe Interaction Network for ULBP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ULBP2 (Q9BZM53 ENSP000003563204) via UniProtKB, MINT, STRING, and/or I2D (see all 70)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIGKQ926433, ENSP000003598484I2D: score=1 STRING: ENSP00000359848
    KLRK1ENSP000002406184STRING: ENSP00000240618
    AZGP1ENSP000002924014STRING: ENSP00000292401
    B2MENSP000003408584STRING: ENSP00000340858
    CD1AENSP000002894294STRING: ENSP00000289429
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response ----
    GO:0019882antigen processing and presentation IBA--
    GO:0030101natural killer cell activation IDA11239445
    GO:0042267natural killer cell mediated cytotoxicity IDA11239445

    ULBP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ULBP2 (N2DL2)

    1 HMDB Compound for ULBP2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ULBP2 gene: 
    NM_025217.2  

    Unigene Cluster for ULBP2:

    UL16 binding protein 2
    Hs.656778  [show with all ESTs]
    Unigene Representative Sequence: BC034689
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367351(uc011eeh.1 uc003qno.3 uc010kij.3)
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ULBP2
      QuantiFast Probe-based Assays in human, mouse, rat ULBP2

    Additional mRNA sequence: 

    AB052906.1 AF304378.1 AF321606.1 AK299895.1 AY026825.1 AY358665.1 BC034689.1 

    1 DOTS entry:

    DT.75158160 

    Selected AceView cDNA sequences (see all 30):

    BF109891 AI492171 AF304378 AA831769 AY358665 CA429924 BU623507 CB991761 
    CN479055 AB052906 CA432454 AI590817 AY026825 AW959307 NM_025217 BU621375 
    AF321606 BQ020367 BG675590 AI168081 CA423879 CB989382 BC034689 AX772820 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ULBP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACCCAATAG
    ULBP2 Expression
    About this image


    ULBP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Lung (Respiratory System)
             Basal Cells Respiratory Bronchioles
     
     Endothelium (Cardiovascular System)
             Endothelial-like cells
    ULBP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ULBP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656778

    UniProtKB/Swiss-Prot: N2DL2_HUMAN, Q9BZM5
    Tissue specificity: Expressed in various types of cancer cell lines and in the fetus, but not in normal tissues

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of mammals.

    Orthologs for ULBP2 gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia --
    --
    32(a)
    1 → many
    1(40635694-40637301)


    ENSEMBL Gene Tree for ULBP2 (if available)
    TreeFam Gene Tree for ULBP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ULBP2 gene
    ULBP12  RAET1G2  ULBP32  RAET1L2  RAET1E2  
    9 SIMAP similar genes for ULBP2 using alignment to 1 protein entry:     N2DL2_HUMAN:
    RAET1H    RAET1L    RAET1G    ULBP1    ULBP3    RAET-1E
    RAET1E    HLA-B    HLA-A

    ULBP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ULBP2 (see all 310)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1386886811,2
    --150260917(+) AGTCGC/TGTTTC 1 -- us2k10--------
    rs1417194271,2
    --150260949(+) ATGGAC/TCAGGG 1 -- us2k10--------
    rs77709951,2
    C,F,A,H--150260952(+) GACCAG/AGGGTC 1 -- us2k1 tfbs38Minor allele frequency- A:0.17NS EA WA CSA 414
    rs65571941,2
    C,F,A,H--150260964(+) TGCCCT/CGACCT 1 -- us2k1 tfbs37Minor allele frequency- C:0.34WA NA CSA EA 364
    rs77478911,2
    C,F,A,H--150260968(+) CTGACT/CTCTGC 1 -- us2k1 tfbs31Minor allele frequency- C:0.00CSA 1
    rs77479011,2
    C,F--150260988(+) CAACCT/CCCACC 1 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1494725841,2
    --150261014(+) CCTGGA/GGGGGC 1 -- us2k10--------
    rs65571971,2
    C,F,A,H--150261029(+) ATGATG/CCTGGG 1 -- us2k15Minor allele frequency- C:0.45NA WA CSA 124
    rs1146408581,2
    C,F--150261076(+) GTGAAC/TATGGA 1 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1438729551,2
    --150261090(+) CCCAGA/GCCCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ULBP2 (150263136 - 150270371 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ULBP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2732866CNV Deletion23290073
    nsv886764CNV Loss21882294
    nsv886765CNV Gain21882294
    nsv517022CNV Gain+Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ULBP2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605698    OMIM disorders: --

    Selected diseases for ULBP2 (see all 22):    
    About MalaCards
    mhc class i deficiency    cytomegalovirus infection    b-cell chronic lymphocytic leukemia    chronic lymphocytic leukemia
    stomatitis    chronic myeloid leukemia    acute myeloid leukemia    malignant glioma
    nasopharyngitis    myeloid leukemia    herpes simplex    bronchiolitis
    hiv-1    hepatitis b    pancreatic cancer    leukemia
    ovarian cancer    pancreatitis    hepatitis    melanoma


    ULBP2 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for ULBP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 15.4 5 16510567 (4)

    Genetic Association Database (GAD): ULBP2
    Human Genome Epidemiology (HuGE) Navigator: ULBP2 (4 documents)

    Export disorders for ULBP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ULBP2 gene, integrated from 10 sources (see all 55):
    (articles sorted by number of sources associating them with ULBP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. (PubMed id 11239445)1, 2, 3 Cosman D.... Chalupny N.J. (Immunity 2001)
    2. Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais. (PubMed id 19688209)1, 4, 9 Romphruk A.V.... Leelayuwat C. (Immunogenetics 2009)
    3. Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations. (PubMed id 20219610)1, 4, 9 Antoun A....Briggs D.C. (Hum. Immunol. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. NKG2D ligands: unconventional MHC class I-like molecules exploited by viruses and cancer. (PubMed id 12753652)1, 2 Cerwenka A. and Lanier L.L. (Tissue Antigens 2003)
    6. Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity. (PubMed id 12782710)1, 2 Dunn C.... Cosman D. (J. Exp. Med. 2003)
    7. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    8. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3. (PubMed id 11827464)1, 2 Radosavljevic M.... Bahram S. (Genomics 2002)
    9. A novel secreted tumor antigen with a glycosylphosphatidylinositol- anchored structure ubiquitously expressed in human cancers. (PubMed id 11444831)1, 2 Onda H.... Fujino M. (Biochem. Biophys. Res. Commun. 2001)
    10. Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain. (PubMed id 19424970)1, 9 Wittenbrink M....Steinle A. (Eur. J. Immunol. 2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80328 HGNC: 14894 AceView: ULBP2 Ensembl:ENSG00000131015 euGenes: HUgn80328
    ECgene: ULBP2 Kegg: 80328 H-InvDB: ULBP2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ULBP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for ULBP2 gene:
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