UHRF1BP1L Gene
protein-coding GIFtS: 41
GCID: GC12M100430
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UHRF1 binding protein 1-like
| |
Aliases
for UHRF1BP1L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| UHRF1 Binding Protein 1-Like1 2 | | KIAA07011 3 | | SHIP1642 | | Syntaxin 6Habc-Interacting Protein Of 164 KDa2 | | UHRF1 (ICBP90) Binding Protein 1-Like2 | | UHRF1-Binding Protein 1-Like2 |
Export aliases for UHRF1BP1L gene to outside databasesPrevious GC identifers: GC12M098954 GC12M097492 |
Summaries
for UHRF1BP1L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for UHRF1BP1L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UHRF1BP1L gene promoter:
AML1a Evi-1 PPAR-gamma1 CP2 POU2F1 POU2F1a PPAR-gamma2 NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for UHRF1BP1L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UHRF1BP1L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q23.1 Ensembl cytogenetic band: 12q23.1 HGNC cytogenetic band: 12q23.1UHRF1BP1L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M100430: view genomic region
(about GC identifiers)
Start:
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100,422,233 bp from pter |
End:
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100,536,642 bp from pter |
Size:
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114,410 bases |
Orientation:
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minus strand |
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Proteins
for UHRF1BP1L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UH1BL_HUMAN, A0JNW5 (See
protein sequence)Recommended Name: UHRF1-binding protein 1-like Size: 1464 amino acids; 164199 Da
Sequence caution: Sequence=AAI27018.1; Type=Frameshift; Positions=1004; Sequence=CAB66755.1; Type=Erroneous initiation;
Secondary accessions: A0PJE5 O75183 Q8NDL1 Q96C30 Q9BTS5 Q9H0F1Alternative splicing: 2 isoforms: A0JNW5-1 A0JNW5-2 Explore the universe of human proteins at neXtProt for UHRF1BP1L: NX_A0JNW5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A0JNW5
UHRF1BP1L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001006948.1 NP_055869.1
ENSEMBL proteins: ENSP00000447809 ENSP00000279907 ENSP00000444824 ENSP00000349285 ENSP00000449112 ENSP00000448226 ENSP00000447043 ENSP00000449189 ENSP00000448420
Human Recombinant Protein Products for UHRF1BP1L:
UHRF1BP1L Antibody Products:
Assay Products for UHRF1BP1L: |
Protein
Domains /
Families
for UHRF1BP1L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UHRF1BP1L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A0JNW5ProtoNet protein and cluster: A0JNW5 |
Function
for UHRF1BP1L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
2 GenomeRNAi human phenotypes for UHRF1BP1L:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UHRF1BP1L (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UHRF1BP1L (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): UHRF1BP1L (NM_015054) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UHRF1BP1L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UHRF1BP1L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UHRF1BP1L |
|
Pathways & Interactions
for UHRF1BP1L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UHRF1BP1L
|
Drugs & Compounds
for UHRF1BP1L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UHRF1BP1L
Search CenterWatch for drugs/clinical trials and news about UHRF1BP1L / UH1BL
|
Transcripts
for UHRF1BP1L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UHRF1BP1L gene (2 alternative transcripts): NM_001006947.1 NM_015054.1 Unigene Cluster for UHRF1BP1L: UHRF1 binding protein 1-like Hs.620701 [show with all ESTs]Unigene Representative Sequence: NM_01505410 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000548712 ENST00000279907(uc001tgp.3 uc001tgq.3) ENST00000545232
ENST00000547504 ENST00000356828(uc001tgr.3) ENST00000548045 ENST00000551973
ENST00000550544 ENST00000551980 ENST00000547428
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UHRF1BP1L (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UHRF1BP1L (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): UHRF1BP1L (NM_015054) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UHRF1BP1L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UHRF1BP1L |
Additional cDNA sequence: AB014601.2 AK026472.1 AK125813.1 AL136821.1 AL833850.1 BC003391.1 BC014891.1 BC026286.1 BC127017.1 BX647380.1 12 DOTS entries: DT.100755451 DT.441492 DT.92021395 DT.91743242 DT.99937085 DT.100681866 DT.121148066 DT.121148189 DT.121148200 DT.75166276 DT.100675664 DT.97789405 24/103 AceView cDNA sequences (see all 103): AA468522 AI499488 AA810003 BQ002093 AL833850 AI671529 AI499509 R26206 AI802947 BQ228202 BU627565 BF001963 AK125813 CA427487 AA614151 AI138440 BC003391 AB014601 AI341296 AL705560 BC026286 BF515875 AL136821 N71435
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for UHRF1BP1L About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 |
|---|
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UHRF1BP1L
|
Expression
for UHRF1BP1L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UHRF1BP1L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTAATGAAA
About this image
See UHRF1BP1L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UHRF1BP1L
SOURCE GeneReport for Unigene cluster: Hs.620701
SABiosciences Custom PCR Arrays for UHRF1BP1L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UHRF1BP1L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UHRF1BP1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UHRF1BP1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UHRF1BP1L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UHRF1BP1L |
Orthologs
for UHRF1BP1L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for UHRF1BP1L gene from 7/23 species (see all 23) About this table
ENSEMBL Gene Tree for UHRF1BP1L (if available)
TreeFam Gene Tree for UHRF1BP1L (if available) |
Paralogs
for UHRF1BP1L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UHRF1BP1L gene
- UHRF1BP12
2 SIMAP similar genes for UHRF1BP1L using alignment to 7 protein entries: UH1BL_HUMAN (see all proteins):DKFZp686A1736 UHRF1BP1
UHRF1BP1L for paralogs About GeneDecksing
|
Genomic Variants
for UHRF1BP1L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UHRF1BP1L (100422233 - 100536642 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for UHRF1BP1L
1 CNV: 43280 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UHRF1BP1L |
|
Disorders
/ Diseases
for UHRF1BP1L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for UHRF1BP1L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UHRF1BP1L gene integrated from 9 sources:
(articles sorted by number of sources associating them with UHRF1BP1L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2 Ishikawa K.... Ohara O. (1998)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- A novel syntaxin 6-interacting protein, SHIP164, regu lates syntaxin 6-dependent sorting from early endosomes. (PubMed id 20163565)1 Otto G.P....Tooze S.A. (2010)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)2 Nakajima D.... Nagase T. (2002)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)2 Wiemann S.... Poustka A. (2001)
|
External Searches for UHRF1BP1L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UHRF1BP1L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UHRF1BP1L gene
(According to HUGE)
About This Section
| |
Specialized Databases showing UHRF1BP1L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UHRF1BP1L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UHRF1BP1L gene:
Search GeneIP for patents involving UHRF1BP1L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UHRF1BP1L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UHRF1BP1L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UHRF1BP1L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UHRF1BP1L | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UHRF1BP1L | | OriGene 3'-UTR Clone for UHRF1BP1L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UHRF1BP1L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UHRF1BP1L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UHRF1BP1L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UHRF1BP1L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UHRF1BP1L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UHRF1BP1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UHRF1BP1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UHRF1BP1L |
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 | | | UHRF1BP1L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UHRF1BP1L |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UHRF1BP1L |
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