UGT8 Gene
protein-coding GIFtS: 60
GCID: GC04P115519
|
|
UDP glycosyltransferase 8(Previous name: UDP-galactose ceramide galactosyltransferase )
(Previous symbol: CGT)
| |
Aliases
for UGT8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| UDP Glycosyltransferase 81 2 | | UDP-Galactose-Ceramide Galactosyltransferase2 3 | | CGT1 2 3 5 | | 2-Hydroxyacylsphingosine 1-Beta-Galactosyltransferase2 | | UDP-Galactose Ceramide Galactosyltransferase1 2 | | Uridine Diphosphate Glycosyltransferase 82 | | Ceramide UDP-Galactosyltransferase2 3 | | EC 2.4.1.453 | | Cerebroside Synthase2 3 | | EC 2.4.18 | | UGT42 3 | | |
Export aliases for UGT8 gene to outside databasesPrevious GC identifers: GC04P115964 GC04P115801 GC04P115978 GC04P116002 GC04P115877 GC04P115739 GC04P111253 |
Summaries
for UGT8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UGT8:
The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactoseto ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of themyelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have beenfound for this gene. (provided by RefSeq, Sep 2011)
UniProtKB/Swiss-Prot: CGT_HUMAN, Q16880Function: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis ofgalactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system andperipheral nervous system
Gene Wiki entry for UGT8
|
Genomic Views
for UGT8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UGT8 gene promoter:
Nkx3-1 ER-alpha Nkx3-1 v4 HOXA3 MyoD POU2F1 Nkx6-1 POU2F1a Chx10
Other transcription factors
Search SABiosciences Chromatin IP Primers for UGT8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q26 Ensembl cytogenetic band: 4q26 HGNC cytogenetic band: 4q26UGT8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P115519: view genomic region
(about GC identifiers)
Start:
|
115,519,611 bp from pter |
End:
|
115,599,380 bp from pter |
Size:
|
79,770 bases |
Orientation:
|
plus strand |
|
Proteins
for UGT8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CGT_HUMAN, Q16880 (See
protein sequence)Recommended Name: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor Size: 541 amino acids; 61438 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: B3KXU7 O00196Explore the universe of human proteins at neXtProt for UGT8: NX_Q16880
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16880
2 DME Specific Peptides for UGT8 (Q16880)
UGT8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001121646.1 NP_003351.2
ENSEMBL proteins: ENSP00000311648 ENSP00000421446 ENSP00000378019
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
UGT8 for ontologies About GeneDecksing
UGT8 Antibody Products:
Assay Products for UGT8: |
Protein
Domains /
Families
for UGT8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UGT8 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q16880ProtoNet protein and cluster: Q16880 1 Blocks protein family: IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase
UniProtKB/Swiss-Prot: CGT_HUMAN, Q16880Similarity: Belongs to the UDP-glycosyltransferase family |
Function
for UGT8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CGT_HUMAN, Q16880Function: Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis ofgalactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system andperipheral nervous systemCatalytic activity: UDP-alpha-D-galactose + 2-(2-hydroxyacyl)sphingosine = UDP +1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine Genatlas biochemistry entry for UGT8:UDP glycosyltransferase 8,UDP-galactose ceramide galactosyl transferase,expressed in the terminal oligodendrocyte (CNS)and in Schwann cell (PNS)
Enzyme Numbers (IUBMB): EC 2.4.12 EC 2.4.1.451
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT8 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 2): UGT8 (NM_001128174) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGT8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT8 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003851 | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity |
IEA | -- | | GO:0008489 | UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity |
IEA | -- |
UGT8 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for UGT8:
Animal Models:
Mouse knock-outs for UGT8: Ugt8atm1Wst Ugt8atm1Pop
6 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Ugt8a):
UGT8 for phenotypes About GeneDecksing
|
Pathways & Interactions
for UGT8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Kegg Pathways (Kegg details for UGT8):
UniProtKB/Swiss-Prot: CGT_HUMAN, Q16880Pathway: Sphingolipid metabolism; galactosylceramide biosynthesis
UGT8 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UGT8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/29 Interacting proteins for UGT8 (ENSP000003116484) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
UGT8 for ontologies About GeneDecksing
|
Drugs & Compounds
for UGT8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
UGT8 for compounds About GeneDecksing
 Browse Tocris compounds for UGT8
10/44 HMDB Compounds for UGT8 (see all 44) About this table
7 Novoseek chemical compound relationships for UGT8 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cerebroside |
85.9 |
4 |
9007051 (2), 17715338 (1), 8661025 (1), 16125333 (1) |
| glycosphingolipid |
80.1 |
3 |
8661123 (1), 11342220 (1), 15901676 (1) |
| ceramide |
79.4 |
14 |
9007051 (2), 15128268 (1), 12540565 (1), 16100442 (1) (see all 10) |
| lactosylceramide |
77.6 |
2 |
12232838 (1), 16100442 (1) |
| sulfatide |
65.9 |
1 |
17715338 (1), 9482258 (1) |
| glycolipid |
58.3 |
1 |
15229398 (1) |
| lipid |
0 |
1 |
17715338 (1), 19187445 (1) |
Search CenterWatch for drugs/clinical trials and news about UGT8 / CGT
|
Transcripts
for UGT8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UGT8 gene (2 alternative transcripts): NM_001128174.1 NM_003360.3 Unigene Cluster for UGT8: UDP glycosyltransferase 8 Hs.744231 [show with all ESTs]Unigene Representative Sequence: NM_0011281743 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000310836(uc003ibs.2 uc011cge.1) ENST00000507710 ENST00000394511(uc003ibt.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT8 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): UGT8 (NM_001128174) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGT8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT8 |
Additional cDNA sequence: AK127970.1 AK225763.1 AK294438.1 AL137342.1 BC075069.2 U30930.1 U62899.1 6 DOTS entries: DT.411084 DT.95233202 DT.121268015 DT.121268014 DT.95154636 DT.97809149 24/67 AceView cDNA sequences (see all 67): CB123316 BU618972 BU171669 BM766906 AA811893 AW188429 H88292 AI499154 AW021247 BX107978 NM_003360 AL118812 BM837159 BP362566 AA553772 BE877255 BC075069 AI357484 N46775 AL137342 CB129676 AU129743 CB410852 CB410784
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for UGT8 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UGT8
|
Expression
for UGT8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UGT8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTTAAAATA
About this image
See UGT8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UGT8
SOURCE GeneReport for Unigene cluster: Hs.744231
SABiosciences Expression via Pathway-Focused PCR Array including UGT8:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGT8
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT8 |
Orthologs
for UGT8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for UGT8 gene from 6/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
UGT81 |
UDP glycosyltransferase 8 |
81.08(n)
84.66(a) |
|
374033 NM_204204.1 NP_989535.1 |
lizard
(Anolis carolinensis) |
Reptilia |
UGT86 |
-- |
83(a) |
1 ↔ 1 |
5(142022789-142044221) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.97272 |
Transcribed sequence with weak similarity to protein more |
77.03(n) |
|
137716941 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:1366521 |
zgc:136652 |
68.29(n)
71.86(a) |
|
553508 NM_001044325.1 NP_001037790.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Ugt86Di3
CG304381 |
glucuronosyltransferase3
CG304381 |
34(a)
(best of 14)3
46.03(n)1
35.2(a)1 |
|
86D73
2466141 NM_165436.21 NP_724417.31 |
worm
(Caenorhabditis elegans) |
Secernentea |
C17G1.33
ugt-581 |
UDP-glucosyltransferase3
Protein UGT-581 |
29(a)
(best of 14)3
44.22(n)1
31.63(a)1 |
|
X(9958179-9960324)3
1745071 NM_063658.51 NP_496059.21 |
ENSEMBL Gene Tree for UGT8 (if available)
TreeFam Gene Tree for UGT8 (if available) |
Paralogs
for UGT8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UGT8 gene
- UGT2A22 UGT1A82 UGT1A72 UGT3A12 UGT2B72 UGT2B112 UGT1A32 UGT1A12
- UGT1A52 UGT3A22 UGT2B102 UGT1A102 UGT1A62 UGT2B152 UGT2B42 UGT2B172
- UGT2A32 UGT2B282 UGT1A92 UGT1A42
18/26 SIMAP similar genes for UGT8 using alignment to 2 protein entries: CGT_HUMAN (see all proteins)
(see all similar genes):UGT2A3 UGT2B10 UGT1A8S UGT2B7 UGT2B11 UGT2B17
UGT2B15 UGT2B4 UGT2B28 UGT3A1 UGT1A8 UGT1A10
UGT1A5 UGT3A2 BILIQTL1 UGT1A3 UGT1A4 UGT1A1
UGT8 for paralogs About GeneDecksing
|
Genomic Variants
for UGT8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for UGT8
3 CNVs: 3508 36183 8451 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT8 |
|
Disorders
/ Diseases
for UGT8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UGT8 for disorders About GeneDecksing
OMIM gene information: 601291
OMIM disorders: --
15  diseases for UGT8: About MalaCardsniemann-pick disease acid sphingomyelinase deficiency metachromatic leukodystrophy pick's disease
leukodystrophy alcohol dependence hearing loss galactosemia
oligodendroglioma alcoholism astrocytoma breast cancer
schizophrenia thyroiditis neuronitis
1 disease from the University of Copenhagen DISEASES database for UGT8:Oligodendroglioma 2 Novoseek disease relationships for UGT8 gene About this table
Human Genome Epidemiology (HuGE) Navigator: UGT8 (4 documents)
Export disorders for UGT8 gene to outside databases
|
Publications
for UGT8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UGT8 gene, integrated from 9 sources (see all 37):
(articles sorted by number of sources associating them with UGT8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. (PubMed id 8661025)1, 2, 3, 9 Bosio A.... Stoffel W. (1996)
- Cloning, characterization, and expression of human ceramide galactosyltransferase cDNA. (PubMed id 9125199)1, 2, 9 Kapitonov D.E. and Yu R.K. (1997)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Gene expression of ceramide kinase, galactosyl cerami de synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer. (PubMed id 19125296)1, 9 RuckhAoberle E....Kaufmann M. (2009)
- The molecular relationship between deficient UDP-galactose uridyl transferase (GALT) and ceramide galactosyltransferase (CGT) enzyme function: a possible cause for poor long-term prognosis in classic galactosemia. (PubMed id 16125333)1, 9 Lebea P.J. and Pretorius P.J. (2005)
- Transcriptional regulation of the human UDP-galactose:ceramide galactosyltransferase (hCGT) gene expression: functional role of GC-box and CRE. (PubMed id 15229398)1, 9 Tencomnao T....Yu R.K. (2004)
- A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1 Kalsi G....Riley B.P. (2010)
- Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases. (PubMed id 20648017)1 Dziecedil Giel P....Ugorski M. (2010)
- Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1 Ross C.J....Hayden M.R. (2009)
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1 Saito A....Kamatani N. (2009)
|
External Searches for UGT8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UGT8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UGT8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UGT8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UGT8 | Pharmacogenomics, SNPs, Pathways | | Functional Glycomics Gateway - GTase | http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_449 |
|
| | |
About This Section
| Patent Information for UGT8 gene:
Search GeneIP for patents involving UGT8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UGT8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UGT8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UGT8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGT8 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UGT8 | | OriGene 3'-UTR Clone for UGT8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UGT8 | | OriGene Custom Protein Services for UGT8 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UGT8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UGT8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGT8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGT8 |
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| | | | Search Tocris compounds for UGT8 |
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 | | | UGT8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT8 |
|  |  |  | | | | Search ThermoFisher Antibodies for UGT8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT8 |
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