Aliases for UGT2B4 Gene
External Ids for UGT2B4 Gene
Previous GeneCards Identifiers for UGT2B4 Gene
GeneCards Summary for UGT2B4 Gene
UGT2B4 (UDP Glucuronosyltransferase Family 2 Member B4) is a Protein Coding gene. Among its related pathways are Farnesoid X Receptor Pathway and Drug metabolism - cytochrome P450. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and glucuronosyltransferase activity. An important paralog of this gene is UGT2B10.
UniProtKB/Swiss-Prot for UGT2B4 Gene
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.