Aliases for UGT2B4 Gene
External Ids for UGT2B4 Gene
GeneCards Summary for UGT2B4 Gene
UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4) is a Protein Coding gene. Diseases associated with UGT2B4 include gilbert syndrome. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include glucuronosyltransferase activity and retinoic acid binding. An important paralog of this gene is UGT2B15.
UniProtKB/Swiss-Prot for UGT2B4 Gene
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid