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UGT2B11 Gene

protein-coding   GIFtS: 55
GCID: GC04M070051

UDP Glucuronosyltransferase 2 Family, Polypeptide B11

(Previous names: UDP glycosyltransferase 2 family, polypeptide B11)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UDP Glucuronosyltransferase 2 Family, Polypeptide B111 2
UDP Glycosyltransferase 2 Family, Polypeptide B111 2
UDPGT 2B112 3
EC 2.4.1.173 8
UDP Glycosyltransferase 2 Family Protein2
UDP-Glucuronosyltransferase 2B112

External Ids:    HGNC: 125451   Entrez Gene: 107202   Ensembl: ENSG000002137597   OMIM: 6030645   UniProtKB: O753103   

Export aliases for UGT2B11 gene to outside databases

Previous GC identifers: GC04M069976 GC04M070114 GC04M070315 GC04M070185 GC04M070187 GC04M069905 GC04M069871 GC04M065861


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UGT2B11 Gene:
UGT2B11 (UDP glucuronosyltransferase 2 family, polypeptide B11) is a protein-coding gene. Diseases associated with UGT2B11 include fascioliasis, and gilbert syndrome. GO annotations related to this gene include glucuronosyltransferase activity. An important paralog of this gene is UGT2A2.

UniProtKB/Swiss-Prot: UDB11_HUMAN, O75310
Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic
xenobiotics and endogenous compounds




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the UGT2B11 gene promoter:
         HOXA9   HOXA9B   FOXD1   Nkx2-5   C/EBPalpha   FAC1   FOXO1a   Meis-1a   Meis-1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUGT2B11 promoter sequence
   Search Chromatin IP Primers for UGT2B11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UGT2B11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.2   Ensembl cytogenetic band:  4q13.2   HGNC cytogenetic band: 4q13.3

UGT2B11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UGT2B11 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M070051:  view genomic region     (about GC identifiers)

Start:
70,065,669 bp from pter      End:
70,080,449 bp from pter
Size:
14,781 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: UDB11_HUMAN, O75310 (See protein sequence)
Recommended Name: UDP-glucuronosyltransferase 2B11 precursor  
Size: 529 amino acids; 61038 Da
Secondary accessions: Q3KNV9

Explore the universe of human proteins at neXtProt for UGT2B11: NX_O75310

Explore proteomics data for UGT2B11 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn315
  • Selected DME Specific Peptides for UGT2B11 (O75310) (see all 30)
     DLLNALK  AFITHGG  MTFMERV  CGKVLVW 


    See UGT2B11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001064.1  
    ENSEMBL proteins: 
     ENSP00000387683  
    Reactome Protein details: O75310

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    UGT: UDP glucuronosyltransferases

    1 InterPro protein domain:
     IPR002213 UDP_glucos_trans

    Graphical View of Domain Structure for InterPro Entry O75310

    ProtoNet protein and cluster: O75310

    1 Blocks protein domain: IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase

    UniProtKB/Swiss-Prot: UDB11_HUMAN, O75310
    Similarity: Belongs to the UDP-glycosyltransferase family


    UGT2B11 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UDB11_HUMAN, O75310
    Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic
    xenobiotics and endogenous compounds
    Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside

         Enzyme Number (IUBMB): EC 2.4.1.171 2

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015020glucuronosyltransferase activity IEA--
    GO:0016758transferase activity, transferring hexosyl groups ----
    GO:0030246carbohydrate binding ----
         
    UGT2B11 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UGT2B11
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2B11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UDB11_HUMAN, O75310: Microsome membrane; Single-pass membrane protein (Potential). Endoplasmic reticulum
    membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    golgi apparatus3
    peroxisome3
    cytosol1
    extracellular1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral component of membrane IEA--

    UGT2B11 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for UGT2B11 About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1Biological oxidations
    Biological oxidations0.56
    Glucuronidation0.00
    Phase II conjugation0.56
    Estradiol metabolism0.00
    metapathway biotransformation0.42
    2Glucuronidation
    Glucuronidation0.61
    Starch and sucrose metabolism0.41
    Ascorbate and aldarate metabolism0.61
    Drug metabolism - other enzymes0.36
    Pentose and glucuronate interconversions0.61
    3Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    4Chemical carcinogenesis
    Chemical carcinogenesis0.71
    Drug metabolism - cytochrome P4500.69
    Metabolism of xenobiotics by cytochrome P4500.71
    Retinol metabolism0.35
    5Metabolism of porphyrins
    Porphyrin and chlorophyll metabolism0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for UGT2B11
        Estradiol metabolism

    2 BioSystems Pathways for UGT2B11
        Glucuronidation
    metapathway biotransformation

    1 Reactome Pathway for UGT2B11
        Glucuronidation


    Selected Kegg Pathways  (Kegg details for UGT2B11) (see all 11):
        Pentose and glucuronate interconversions
    Ascorbate and aldarate metabolism
    Steroid hormone biosynthesis
    Starch and sucrose metabolism
    Retinol metabolism


    UGT2B11 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UGT2B11
    Interactions:

        Search GeneGlobe Interaction Network for UGT2B11

    1 Interacting protein for UGT2B11 (O753103) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PIK3C2AO004433I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process ----
    GO:0006805xenobiotic metabolic process TAS8333863
    GO:0008152metabolic process ----
    GO:0008210estrogen metabolic process TAS8333863
    GO:0030259lipid glycosylation ----

    UGT2B11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UGT2B11 (UDB11)

    Selected HMDB Compounds for UGT2B11 (see all 85)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Retinyl beta-glucuronideRetinyl b-glucuronide (see all 2)--8600986
    (23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)(23S)-23,25-dihydroxy-24-oxovitamin D3 23-(beta-glucuronide) (see all 5)----
    1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acidIbuprofen acyl glucuronide;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[4-(2-methylpropyl)phenyl]propanoyloxy]oxane-2-carboxylic acid (see all 5)115075-59-7--
    1-Salicylate glucuronide1-salicylic acid glucuronide ----
    11-Hydroxyprogesterone 11-glucuronide11-hydroxyprogesterone 11-glucuronoside (see all 5)77710-64-6--
    11-Oxo-androsterone glucuronide11-oxo-etiocholanolone glucuronide (see all 3)----
    11-beta-hydroxyandrosterone-3-glucuronide11-beta-hydroxyetiocholanolone-3-glucuronide ----
    15-hydroxynorandrostene-3,17-dione glucuronide15-HNADG (see all 5)131749-23-0--
    16-alpha,17-beta-estriol 17-beta-D-glucuronideestra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide (see all 7)7219-89-8--
    17-alpha-estradiol-3-glucuronide ----



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for UGT2B11 gene: 
    NM_001073.1  

    Unigene Cluster for UGT2B11:

    UDP glucuronosyltransferase 2 family, polypeptide B11
    Hs.339811  [show with all ESTs]
    Unigene Representative Sequence: AF016492
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000446444(uc003heh.3) ENST00000513315
    miRNA
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    Additional mRNA sequence: 

    AF016492.1 BC069441.1 BC107059.2 BC107060.2 

    4 DOTS entries:

    DT.121232122  DT.91817318  DT.100717704  DT.95255211 

    9 AceView cDNA sequences:

    AF016492 BX485008 NM_001073 BC069441 BX485009 BG215131 BG195984 N70316 
    BG214065 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UGT2B11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCTCACCTG
    UGT2B11 Expression
    About this image


    UGT2B11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced embryoid bodies
    UGT2B11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UGT2B11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.339811

    UniProtKB/Swiss-Prot: UDB11_HUMAN, O75310
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2B11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for UGT2B11 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    fruit fly
    (Drosophila melanogaster)
    Insecta Ugt86Da3
    CG64751
    glucuronosyltransferase3
    CG64751
    35(a)
    (best of 16)3
    47.38(n)1
    32.64(a)1
      86D73
    425381  NM_001104389.31  NP_001097859.41 
            Species with no ortholog for UGT2B11

    ENSEMBL Gene Tree for UGT2B11 (if available)
    TreeFam Gene Tree for UGT2B11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UGT2B11 gene
    UGT2A22  UGT1A82  UGT3A12  UGT1A72  UGT2B72  UGT1A32  UGT1A12  UGT3A22  
    UGT1A52  UGT2B102  UGT2A12  UGT1A102  UGT1A62  UGT82  UGT2B152  UGT2B42  
    UGT2A32  UGT2B172  UGT2B282  UGT1A92  UGT1A42  
    Selected SIMAP similar genes for UGT2B11 using alignment to 2 protein entries:     UDB11_HUMAN (see all proteins) (see all similar genes):
    UGT2B28    UGT2B4    UGT2B7    UGT2B15    UGT2B17    UGT2B10
    UGT2A3    UGT2A2    UGT2A1    UGT1A9S    BILIQTL1    UGT1A8S
    UGT1A5    UGT1A4    UGT1A6    UGT1A8    UGT1A1    UGT1A4S

    UGT2B11 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for UGT2B11
    PGOHUM00000245941 PGOHUM00000245942 PGOHUM00000250781


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UGT2B11 (see all 465)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1485264991,2
    Cuntested170079955(+) AGTAGC/TGCAGC 2 A syn10--------
    rs1897915331,2
    --70065539(+) TGACAA/TGAGCT 1 -- ds50010--------
    rs1811600281,2
    --70065567(+) TTGGCA/CATCAA 1 -- ds50010--------
    rs1502233541,2
    C--70065666(+) ACTTTA/TTATAC 1 -- ds50010--------
    rs795995551,2
    C,F--70065668(+) TTTATA/GTACAA 1 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1855631521,2
    --70065754(+) AGGATA/GTGACT 1 -- ds50010--------
    rs1457474901,2
    C--70065801(+) TTTATA/GTAAAA 1 -- ds50010--------
    rs1416275221,2
    C--70065887(+) GCAACA/GAATTT 1 -- ds50010--------
    rs772359611,2
    C--70065928(+) TTTTAA/TTTTTC 1 -- ds50010--------
    rs780901651,2
    C,F--70065947(+) TTCTTC/TATTGC 1 -- ds50012Minor allele frequency- T:0.03NA EA 240

    HapMap Linkage Disequilibrium report for UGT2B11 (70065669 - 70080449 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for UGT2B11 (see all 27):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670036CNV Deletion23128226
    esv2727775CNV Deletion23290073
    esv2727780CNV Deletion23290073
    dgv891e201CNV Deletion23290073
    esv2671471CNV Deletion23128226
    dgv17n31CNV Duplication19718026
    dgv5608n71CNV Loss21882294
    dgv5610n71CNV Loss21882294
    nsv879384CNV Loss21882294
    nsv879395CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UGT2B11
    DNA2.0 Custom Variant and Variant Library Synthesis for UGT2B11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603064    OMIM disorders: --

    6 diseases for UGT2B11:    
    About MalaCards
    fascioliasis    gilbert syndrome    prostate cancer    breast cancer
    prostatitis    endotheliitis

    2 diseases from the University of Copenhagen DISEASES database for UGT2B11:
    Gilbert syndrome     Prostate cancer

    UGT2B11 for disorders           About GeneDecksing

    Genetic Association Database (GAD): UGT2B11
    Human Genome Epidemiology (HuGE) Navigator: UGT2B11 (14 documents)

    Export disorders for UGT2B11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UGT2B11 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with UGT2B11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a human orphan UDP- glucuronosyltransferase, UGT2B11. (PubMed id 9675083)1, 2, 3 Beaulieu M.... Belanger A. (Biochem. Biophys. Res. Commun. 1998)
    2. Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer. (PubMed id 20214802)1, 4 Li J....Hall P. (Breast Cancer Res. 2010)
    3. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    4. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1, 4 Ross C.J....Hayden M.R. (Nat. Genet. 2009)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Quantitative analysis of UGT2B28 mRNA expression by real-time RT-PCR and application to human tissue distribution study. (PubMed id 21679149)1 Ohno S. and Nakajin S. (Drug Metab Lett 2011)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Formation of beta-glucuronides and of beta-galacturonides of various retinoids catalyzed by induced and noninduced microsomal UDP-glucuronosyltransferases of rat liver. (PubMed id 8600986)6 Genchi G....Olson J.A. (Biochim. Biophys. Acta 1996)
    9. cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily. (PubMed id 8333863)1 Jin C.-J.... McKenzie P.I. (Biochem. Biophys. Res. Commun. 1993)
    10. The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases. (PubMed id 8269638)9 Jin C.J....Mackenzie P.I. (Carcinogenesis 1993)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10720 HGNC: 12545 AceView: UGT2B11 Ensembl:ENSG00000213759 euGenes: HUgn10720
    ECgene: UGT2B11 Kegg: 10720 H-InvDB: UGT2B11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UGT2B11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UGT2B11 gene:
    Search GeneIP for patents involving UGT2B11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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