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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

UGT2B10 Gene

protein-coding GIFtS: 57
GCID: GC04P069730

UDP glucuronosyltransferase 2 family, polypeptide B10

(Previous names: UDP glycosyltransferase 2 family, polypeptide B10 )

Explore 3 diseases affiliated with
UGT2B10 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UDP Glucuronosyltransferase 2 Family, Polypeptide B10¹ ²		UDPGT2B10²
UDPGT 2B10² ³		UDP Glucuronosyltransferase 2B10²
EC 2.4.1.17³ ⁸		UDP-Glucuronosyltransferase 2B10²
UDP Glycosyltransferase 2 Family, Polypeptide B10¹

External Ids:	HGNC: 12544¹	Entrez Gene: 7365²	Ensembl: ENSG00000109181⁷	OMIM: 600070⁵	UniProtKB: P36537³

Export aliases for UGT2B10 gene to outside databases

Previous GC identifers: GC04P069592 GC04P069931 GC04P069997 GC04P069862 GC04P065477

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: UDB10_HUMAN, P36537

Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics

and endogenous compounds

Gene Wiki entry for UGT2B10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_022778.16 NT_167250.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the UGT2B10 gene promoter:
C/EBPbeta AML1a FOXD1 FOXO1a Meis-1a Pax-4a FOXO1 Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UGT2B10 promoter sequence

Search SABiosciences Chromatin IP Primers for UGT2B10

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT2B10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13.2 Ensembl cytogenetic band: 4q13.2 HGNC cytogenetic band: 4q13.3

UGT2B10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UGT2B10 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04P069730: view genomic region (about GC identifiers)

Start:	69,681,711 bp from pter	End:	69,697,741 bp from pter
Size:	16,031 bases	Orientation:	plus strand

2 alternative locations:

Chr4+ 69,564,040-69,580,068

Chr4+,ALT_REF_LOCI_8 69,622,876-69,638,904

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UDB10_HUMAN, P36537 (See protein sequence)

Recommended Name: UDP-glucuronosyltransferase 2B10 precursor

Size: 528 amino acids; 60774 Da

Subcellular location: Microsome membrane; Single-pass membrane protein (Potential). Endoplasmic reticulum membrane;

Single-pass membrane protein (Potential)

Secondary accessions: A8K9M3 Q14CR8

Explore the universe of human proteins at neXtProt for UGT2B10: NX_P36537

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P36537

4/33 DME Specific Peptides for UGT2B10 (P36537) (see all 33)

DLLNALK

AFITHGG

LLGHPKT

FVQSSGE

UGT2B10 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001066.1 NP_001138239.1

ENSEMBL proteins:

ENSP00000265403 ENSP00000413420

Reactome Protein details: P36537
Human Recombinant Protein Products for UGT2B10:

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	Novus Biologicals UGT2B10 Protein Novus Biologicals UGT2B10 Lysate
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	Uscn Proteins for UGT2B10

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0005792	microsome	--	--
GO:0016021	integral to membrane	IEA	--

UGT2B10 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for UGT2B10

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UGT2B10 for domains About GeneDecksing

1 InterPro domain/family:

IPR002213 UDP_glucos_trans

Graphical View of Domain Structure for InterPro Entry P36537

ProtoNet protein and cluster: P36537

1 Blocks protein family: IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase

UniProtKB/Swiss-Prot: UDB10_HUMAN, P36537

Similarity: Belongs to the UDP-glycosyltransferase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: UDB10_HUMAN, P36537

Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics

and endogenous compounds

Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside

Enzyme Number (IUBMB): EC 2.4.1.17¹ ²

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015020	glucuronosyltransferase activity	IEA	--
GO:0016758	transferase activity, transferring hexosyl groups	--	--

UGT2B10 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for UGT2B10:

Increased G1 DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for UGT2B10

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2B10

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Glucuronidation

Glucuronidation	1.00	Porphyrin and chlorophyll metabolism	0.38
Glucuronidation	0.67	Other types of O-glycan biosynthesis	0.36
Starch and sucrose metabolism	0.42	Drug metabolism - other enzymes	0.32

Drug metabolism - cytochrome P450

	Drug metabolism - cytochrome P450	1.00			Retinol metabolism	0.40
	Metabolism of xenobiotics by cytochrome P450	0.73

Metabolism

Metabolism

1.00

Metabolic pathways

0.38

Pentose and glucuronate interconversions

Pentose and glucuronate interconversions

1.00

Ascorbate and aldarate metabolism

0.62

Biological oxidations

Biological oxidations

1.00

Phase II conjugation

0.52

Pathway sources
See GeneCards unified pathways
Show all pathways

1 BioSystems Pathway for UGT2B10

Glucuronidation

4 Reactome Pathways for UGT2B10

	Metabolism
	Biological oxidations
	Phase II conjugation
	Glucuronidation

1 PharmGKB Pathway for UGT2B10

Nicotine Pathway, Pharmacokinetics

5/11 Kegg Pathways (Kegg details for UGT2B10) (see all 11):

	Pentose and glucuronate interconversions
	Ascorbate and aldarate metabolism
	Steroid hormone biosynthesis
	Starch and sucrose metabolism
	Other types of O-glycan biosynthesis

UGT2B10 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for UGT2B10

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/57 Interacting proteins for UGT2B10 (ENSP00000265403⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 57)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ADH4	ENSP00000265512⁴	STRING: ENSP00000265512
ADH6	ENSP00000378359⁴	STRING: ENSP00000378359
ADH7	ENSP00000209665⁴	STRING: ENSP00000209665
AKR1C4	ENSP00000263126⁴	STRING: ENSP00000263126
AKR1D1	ENSP00000242375⁴	STRING: ENSP00000242375

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006629	lipid metabolic process	TAS	8333863

UGT2B10 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

UGT2B10 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UGT2B10

10/84 HMDB Compounds for UGT2B10 (see all 84) About this table

Compound	Synonyms	CAS #	PubMed Ids
(23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)	(23S)-23,25-dihydroxy-24-oxovitamin D3 23-(beta-glucuronide) (see all 5)	--	--
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid	Ibuprofen acyl glucuronide;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[4-(2-methylpropyl)phenyl]propanoyloxy]oxane-2-carboxylic acid (see all 5)	115075-59-7	--
1-Salicylate glucuronide	1-salicylic acid glucuronide	--	--
11-Hydroxyprogesterone 11-glucuronide	11-hydroxyprogesterone 11-glucuronoside (see all 5)	77710-64-6	--
11-Oxo-androsterone glucuronide	11-oxo-etiocholanolone glucuronide (see all 3)	--	--
11-beta-hydroxyandrosterone-3-glucuronide	11-beta-hydroxyetiocholanolone-3-glucuronide	--	--
15-hydroxynorandrostene-3,17-dione glucuronide	15-HNADG (see all 5)	131749-23-0	--
16-alpha,17-beta-estriol 17-beta-D-glucuronide	estra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide (see all 7)	7219-89-8	--
17-alpha-estradiol-3-glucuronide		--	--
17-beta-estradiol glucuronide		--	--

1 Novoseek chemical compound relationship for UGT2B10 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
steroid	17.9	2	11159850 (1)

1 PharmGKB related drug/compound annotation for UGT2B10 gene About this table

Drug/compound	PharmGKB Annotation
nicotine	CA

Search CenterWatch for drugs/clinical trials and news about UGT2B10 / UDB10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for UGT2B10 gene (2 alternative transcripts):

NM_001075.4 NM_001144767.1

Unigene Cluster for UGT2B10:

UDP glucuronosyltransferase 2 family, polypeptide B10

Hs.201634 [show with all ESTs]

Unigene Representative Sequence: NM_001075

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000265403(uc003hee.3 uc011cam.2) ENST00000458688

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Additional cDNA sequence:

AK222839.1 AK222872.1 AK292738.1 AK298432.1 BC113649.1

4 DOTS entries:

DT.100783300 DT.100814505 DT.434931 DT.91741715

24/35 AceView cDNA sequences (see all 35):

NM_001075 H69250 T46839 T57898 CD013995 CD013994 CB164598 CB113377

CB161428 BV199399 BG201991 BV172697 AI688814 AV696157 BV201798 BV199398

BV199400 BG189133 CD610478 AI032906 R00510 BG212458 T57980 N78136

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

UGT2B10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGATTTCAA

About this image

UGT2B10 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Renal Collecting Duct System

Kidney

Liver

Liver Lobule

Liver

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See UGT2B10 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.201634

SABiosciences Expression via Pathway-Focused PCR Array including UGT2B10:

Drug Metabolism: Phase II Enzymes in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2B10

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for UGT2B10 gene from 3/8 species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	F1NMB3_CHICK⁶	Uncharacterized protein	56(a)	1 → many	4(53288491-53295396)
lizard (Anolis carolinensis)	Reptilia	-- --	--	56(a) 55(a)	many ↔ many many ↔ many	6(58629882-58649612) 6(58564243-58578541)
zebrafish (Danio rerio)	Actinopterygii	BX571679.1⁶ ugt2a4⁶ (see all 15)	-- UDP glucuronosyltransferase 2 family, polypeptide ... (see all 15)	65(a) 52(a) (see all 15)	many ↔ many many ↔ many (see all 15)	5(9986135-9988976) 5(72956618-72977951)

ENSEMBL Gene Tree for UGT2B10 (if available)
TreeFam Gene Tree for UGT2B10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for UGT2B10 gene

UGT2A2² UGT1A8² UGT1A7² UGT3A1² UGT2B7² UGT2B11² UGT1A3² UGT1A1²

UGT1A5² UGT3A2² UGT1A10² UGT1A6² UGT8² UGT2B15² UGT2B4² UGT2B17²

UGT2A3² UGT2B28² UGT1A9² UGT1A4²

18/27 SIMAP similar genes for UGT2B10 using alignment to 2 protein entries: UDB10_HUMAN (see all proteins) (see all similar genes):

UGT2B11 UGT2B28 UGT2B7 UGT2B4 UGT2B17 UGT2A3

UGT2B15 UGT1A3S UGT1A9S UGT2A1 UGT8 UGT1A5

UGT1A8S UGT1A6 BILIQTL1 UGT1A7 UGT1A8 UGT3A2

UGT2B10 for paralogs About GeneDecksing

5/7 Pseudogenes.org Pseudogenes for UGT2B10 (see all 7)
PGOHUM00000248150 PGOHUM00000259898 PGOHUM00000259900 PGOHUM00000259901 PGOHUM00000259902

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 4 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs66701588^1,2	C	--	65475622(+)	`TTTTG-/TTTTCT`	1	--	us2k¹		0	--	--	--	--
rs113242232^1,2	C	--	65475640(+)	`ATGCTA/GACAGT`	1	--	us2k¹		0	--	--	--	--
rs116753273^1,2	C,F	--	65476634(+)	`ACATGT/CCTACA`	1	--	us2k¹		1		WA	118
rs11725502^1,2	C,H	--	65476830(+)	`cactgA/Taaaat`	1	--	us2k¹ tfbs³		3		NA WA	240
rs77277972^1,2		--	65476831(+)	`ACTGAA/TAAATG`	1	--	us2k¹		3		NA WA	240
rs72849033^1,2	C	--	65476843(+)	`ATAAAC/TAATTT`	1	--	us2k¹		1		WA	2
rs116220786^1,2	C,F	--	65477379(+)	`AAACAC/TGATAT`	1	--	us2k¹		1		WA	118
rs113556972^1,2	C	--	65477507(+)	`GGATGC/TTCATA`	1	--	us2k¹		0	--	--	--	--
rs59369392^1,2		--	65477536(+)	`TTGAAA/GGAGTT`	1	--	us2k¹		0	--	--	--	--
rs59166765^1,2	C,F	--	65477599(+)	`TGACTG/TGAAAA`	1	--	us2k¹		1		EU	593

HapMap Linkage Disequilibrium report for UGT2B10 (69681711 - 69697741 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for UGT2B10
7 CNVs: 32614 3499 2527 63854 80350 2526 37736
Human Gene Mutation Database (HGMD): UGT2B10

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

UGT2B10 for disorders           About GeneDecksing

OMIM gene information: 600070    OMIM disorders: --

3 diseases for UGT2B10:    About MalaCards

gilbert syndrome cholesterol hepatitis

2 diseases from the University of Copenhagen DISEASES database for UGT2B10:

Gilbert syndrome Prostate cancer

Human Genome Epidemiology (HuGE) Navigator: UGT2B10 (3 documents)

Export disorders for UGT2B10 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for UGT2B10 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with UGT2B10)

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cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily. (PubMed id 8333863)^{1, 2, 3} Jin C.-J.... McKenzie P.I. (1993)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{1, 2} Liu T.... Smith R.D. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines. (PubMed id 18300939)^{1, 9} Chen G....Lazarus P. (2008)
Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10. (PubMed id 17576790)^{1, 9} Kaivosaari S....Finel M. (2007)
Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. (PubMed id 10024527)^{1, 9} Strassburg C.P....Tukey R.H. (1999)
Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. (PubMed id 22228205)¹ Chen G....Lazarus P. (2012)
Glucuronidation genotypes and nicotine metabolic phen otypes: importance of functional UGT2B10 and UGT2B17 polymorphisms. (PubMed id 20876810)¹ Chen G....Lazarus P. (2010)
Expression levels of uridine 5'-diphospho-glucuronosy ltransferase genes in breast tissue from healthy women are associated with mamm ographic density. (PubMed id 20799965)¹ Haakensen V.D....LingjA (2010)
UGT2B10 genotype influences nicotine glucuronidation, oxidation, and consumption. (PubMed id 20501767)¹ Berg J.Z....Murphy S.E. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 7365	HGNC: 12544	AceView: UGT2B10	Ensembl:ENSG00000109181	euGenes: HUgn7365
ECgene: UGT2B10	Kegg: 7365	H-InvDB: UGT2B10

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for UGT2B10	Pharmacogenomics, SNPs, Pathways

Intellectual Property for UGT2B10 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for UGT2B10 gene:
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UGT2B10 Gene

UDP glucuronosyltransferase 2 family, polypeptide B10

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UGT2B10 Gene

UDP glucuronosyltransferase 2 family, polypeptide B10

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