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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UGT2A1 Gene

protein-coding   GIFtS: 59
GCID: GC04M070454

UDP glucuronosyltransferase 2 family, polypeptide A1, complex...

(Previous names: UDP glycosyltransferase 2 family, polypeptide A1, UDP glucuronosyltransferase...)
 Explore 4 diseases affiliated with
UGT2A1 via our new
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Biological research products
for UGT2A1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus1 2     UDP Glucuronosyltransferase 2 Family, Polypeptide A11
UDP Glycosyltransferase 2 Family, Polypeptide A11 2     UDP-Glucuronosyltransferase 2A12
UDPGT 2A12 3     UGT2A23
EC 2.4.1.173 8     

External Ids:    HGNC: 125421   Entrez Gene: 109412   Ensembl: ENSG000001736107   OMIM: 6047165   UniProtKB: Q9Y4X13   

Export aliases for UGT2A1 gene to outside databases

Previous GC identifers: GC04P070020 GC04M070503 GC04M070704 GC04M070770 GC04M070635


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UGT2A1:
The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze
biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water
solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of
potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium,
which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence,
this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by
RefSeq, Nov 2011)

UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1
Function: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are
conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in
the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on
odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory
epithelium

Gene Wiki entry for UGT2A1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_022778.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UGT2A1 gene promoter:
         POU2F2 (Oct-2.1)   oct-B3   oct-B2   STAT5A   Cdc5   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUGT2A1 promoter sequence
   Search SABiosciences Chromatin IP Primers for UGT2A1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT2A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q13   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q13

UGT2A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UGT2A1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M070454:  view genomic region     (about GC identifiers)

Start:
70,454,135 bp from pter      End:
70,518,967 bp from pter
Size:
64,833 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1 (See protein sequence)
Recommended Name: UDP-glucuronosyltransferase 2A1 precursor  
Size: 527 amino acids; 59926 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Caution: According to HGNC, UGT2A1 and UGT2A2 are 2 separate genes. However, they share common exons at the C-terminus,
suggesting that UGT2A1 and UGT2A2 are different isoforms encoded by the same locus
Secondary accessions: B4E2F4 D3GER1 D3GER2 E9PDM7 J3KNA3
Alternative splicing: 5 isoforms:  Q9Y4X1-1   Q9Y4X1-2   Q9Y4X1-3   Q9Y4X1-4   Q9Y4X1-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UGT2A1: NX_Q9Y4X1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y4X1

  • 4/19 DME Specific Peptides for UGT2A1 (Q9Y4X1) (see all 19)
     AFITHGG  SHWLNVK  LLGHPKT  QYHSLDV 

    UGT2A1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001239203.1  NP_001239204.1  NP_006789.2  

    ENSEMBL proteins: 
     ENSP00000424478   ENSP00000421432   ENSP00000425497   ENSP00000286604   ENSP00000427709  
     ENSP00000387888  
    Reactome Protein details: Q9Y4X1
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    Uscn Proteins for UGT2A1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    UGT2A1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    UGT2A1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR002213 UDP_glucos_trans

    Graphical View of Domain Structure for InterPro Entry Q9Y4X1

    ProtoNet protein and cluster: Q9Y4X1

    1 Blocks protein family: IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase

    UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1
    Similarity: Belongs to the UDP-glycosyltransferase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1
    Function: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are
    conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in
    the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on
    odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory
    epithelium
    Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside
    Biophysicochemical properties: Kinetic parameters: KM=75.4 uM for 3-hydroxybiphenyl; KM=59.5 uM for umbelliferone;
    KM=51.6 uM for S-(-)-b-citronellol; KM=170.1 uM for borneol; KM=56.2 uM for testosterone; KM=251 uM for
    UDP-glucuronate; Vmax=2.60 nmol/min/mg enzyme with 3-hydroxybiphenyl as substrate; Vmax=0.61 nmol/min/mg enzyme with
    umbelliferone as substrate; Vmax=1.98 nmol/min/mg enzyme with S-(-)-b-citronellol as substrate; Vmax=1.05 nmol/min/mg
    enzyme with borneol as substrate; Vmax=0.25 nmol/min/mg enzyme with testosterone as substrate;

         Genatlas biochemistry entry for UGT2A1:
    UDP glucoronosyltransferase 2 alpha 1,specific for the olfactory tissue

    Enzyme Number (IUBMB): EC 2.4.1.171 2

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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015020glucuronosyltransferase activity IEA--
    GO:0016758transferase activity, transferring hexosyl groups ----


    UGT2A1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for UGT2A1:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Glucuronidation
    Glucuronidation1.00
    Porphyrin and chlorophyll metabolism0.38
    Glucuronidation0.67
    Other types of O-glycan biosynthesis0.36
    Starch and sucrose metabolism0.42
    Drug metabolism - other enzymes0.32
    2Drug metabolism - cytochrome P450
    Drug metabolism - cytochrome P4501.00
    Retinol metabolism0.40
    Metabolism of xenobiotics by cytochrome P4500.73
    3Biological oxidations
    Biological oxidations1.00
    metapathway biotransformation0.41
    Phase II conjugation0.52
    4Metabolism
    Metabolism1.00
    Metabolic pathways0.38
    5Pentose and glucuronate interconversions
    Pentose and glucuronate interconversions1.00
    Ascorbate and aldarate metabolism0.62

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2 BioSystems Pathways for UGT2A1 
        Glucuronidation
    metapathway biotransformation

    4        Reactome Pathways for UGT2A1
        Metabolism
    Biological oxidations
    Phase II conjugation
    Glucuronidation


    5/11         Kegg Pathways  (Kegg details for UGT2A1) (see all 11):
        Pentose and glucuronate interconversions
    Ascorbate and aldarate metabolism
    Steroid hormone biosynthesis
    Starch and sucrose metabolism
    Other types of O-glycan biosynthesis


    UGT2A1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UGT2A1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/56 Interacting proteins for UGT2A1 (ENSP000002866044) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AKR1D1ENSP000002423754STRING: ENSP00000242375
    ALDH1A1ENSP000002977854STRING: ENSP00000297785
    CES2ENSP000003178424STRING: ENSP00000317842
    COMTENSP000003545114STRING: ENSP00000354511
    CYP1A1ENSP000003690504STRING: ENSP00000369050
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007608sensory perception of smell IEA--
    GO:0008152metabolic process TAS10359671
    GO:0009593detection of chemical stimulus TAS10359671
    GO:0052695cellular glucuronidation IDA19858781


    UGT2A1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for UGT2A1

    10/83 HMDB Compounds for UGT2A1 (see all 83)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)(23S)-23,25-dihydroxy-24-oxovitamin D3 23-(beta-glucuronide) (see all 5)----
    1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acidIbuprofen acyl glucuronide;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[4-(2-methylpropyl)phenyl]propanoyloxy]oxane-2-carboxylic acid (see all 5)115075-59-7--
    1-Salicylate glucuronide1-salicylic acid glucuronide ----
    11-Hydroxyprogesterone 11-glucuronide11-hydroxyprogesterone 11-glucuronoside (see all 5)77710-64-6--
    11-Oxo-androsterone glucuronide11-oxo-etiocholanolone glucuronide (see all 3)----
    11-beta-hydroxyandrosterone-3-glucuronide11-beta-hydroxyetiocholanolone-3-glucuronide ----
    15-hydroxynorandrostene-3,17-dione glucuronide15-HNADG (see all 5)131749-23-0--
    16-alpha,17-beta-estriol 17-beta-D-glucuronideestra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide (see all 7)7219-89-8--
    17-alpha-estradiol-3-glucuronide ----
    17-beta-estradiol glucuronide ----
    Search CenterWatch for drugs/clinical trials and news about UGT2A1 / UD2A1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for UGT2A1 gene (3 alternative transcripts): 
    NM_001252274.1  NM_001252275.1  NM_006798.3  

    Unigene Cluster for UGT2A1:

    UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
    Hs.225950  [show with all ESTs]
    Unigene Representative Sequence: NM_001252274
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000503640(uc003hem.4 uc011caq.2 uc010ihu.3) ENST00000512704(uc010iht.3)
    ENST00000514019 ENST00000286604 ENST00000502343 ENST00000514341 ENST00000505512
    ENST00000457664(uc010ihs.3 uc021xox.1)

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    Additional cDNA sequence: 

    AJ006054.1 AK304249.1 AK314209.1 BC142640.1 FJ664272.1 FJ664273.1 

    2 DOTS entries:

    DT.92415436  DT.91913500 

    7 AceView cDNA sequences:

    BX283268 AJ006054 NM_006798 CD105882 BG400151 BG185464 BG186196 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UGT2A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTATTATTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See UGT2A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UGT2A1

    SOURCE GeneReport for Unigene cluster: Hs.225950

    UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1
    Tissue specificity: Olfactory epithelium and brain. Isoform 2 is mainly expressed in the nasal mucosa

        SABiosciences Expression via Pathway-Focused PCR Arrays including UGT2A1: 
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for UGT2A1 gene from 1/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.114192 Transcribed sequence with moderate similarity to protein more 75.84(n)    CK028589.1 


    ENSEMBL Gene Tree for UGT2A1 (if available)
    TreeFam Gene Tree for UGT2A1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UGT2A1 gene
    UGT1A82  UGT1A72  UGT3A12  UGT2B72  UGT2B112  UGT1A32  UGT1A12  UGT1A52  
    UGT3A22  UGT2B102  UGT1A102  UGT1A62  UGT82  UGT2B152  UGT2B42  UGT2B172  
    UGT2A32  UGT2B282  UGT1A92  UGT1A42  
    18/29 SIMAP similar genes for UGT2A1 using alignment to 3 protein entries:     UD2A1_HUMAN (see all proteins) (see all similar genes):
    UGT2A3    UGT2B11    UGT2B4    UGT2B17    UGT2B28    UGT2B15
    UGT2B7    UGT2B10    UGT1A3S    UGT1A9S    UGT1A6    UGT1
    UGT1A1    BILIQTL1    UGT1A8S    UGT1A6S    UGT1A10    UGT1A5

    UGT2A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 16 variations for UGT2A1
         15 CNVs: 92191 80359 92189 23048 22681 36292 80360 92188 7451 6276 53271 80358 36293 92190 63855
         1 Indel: 80361
    Human Gene Mutation Database (HGMD): UGT2A1
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT2A1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    UGT2A1 for disorders           About GeneDecksing

    OMIM gene information: 604716    OMIM disorders: --

    4 diseases for UGT2A1:    About MalaCards
    kernicterus    hearing loss    fascioliasis    cholesterol

    3 diseases from the University of Copenhagen DISEASES database for UGT2A1:
    Fascioliasis     Kernicterus     Gilbert syndrome
    Human Genome Epidemiology (HuGE) Navigator: UGT2A1 (3 documents)

    Export disorders for UGT2A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UGT2A1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with UGT2A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel human olfactory UDP- glucuronosyltransferase. (PubMed id 10359671)1, 2, 3 Jedlitschky G.A.... Burchell B. (1999)
    2. Human UDP-glucuronosyltransferase UGT2A2: cDNA constr uction, expression, and functional characterization in comparison with UGT2A1 a nd UGT2A3. (PubMed id 19858781)1, 2 Sneitz N....Finel M. (2009)
    3. Identification and functional characterization of a no vel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in toba cco-related cancer susceptibility. (PubMed id 22984225)1 Bushey R.T. and Lazarus P. (2012)
    4. Characterization of UDP-glucuronosyltransferase 2A1 ( UGT2A1) variants and their potential role in tobacco carcinogenesis. (PubMed id 21164388)1 Bushey R.T....Lazarus P. (2011)
    5. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1 Saito A....Kamatani N. (2009)
    6. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1 Ross C.J....Hayden M.R. (2009)
    7. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    8. Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. (PubMed id 16141793)1 Mackenzie P.I....Nebert D.W. (2005)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8. (PubMed id 12376738)1 Iida A....Nakamura Y. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10941 HGNC: 12542 AceView: UGT2A1 Ensembl:ENSG00000173610 euGenes: HUgn10941
    ECgene: UGT2A1 Kegg: 10941 H-InvDB: UGT2A1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UGT2A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for UGT2A1 gene:
    Search GeneIP for patents involving UGT2A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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