UGT2A1 Gene
protein-coding GIFtS: 59
GCID: GC04M070454
|
|
UDP glucuronosyltransferase 2 family, polypeptide A1, complex...(Previous names: UDP glycosyltransferase 2 family, polypeptide A1, UDP glucuronosyltransferase...)
| |
Aliases for UGT2A1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus1 2 | | UDP Glucuronosyltransferase 2 Family, Polypeptide A11 | | UDP Glycosyltransferase 2 Family, Polypeptide A11 2 | | UDP-Glucuronosyltransferase 2A12 | | UDPGT 2A12 3 | | UGT2A23 | | EC 2.4.1.173 8 | | |
Export aliases for UGT2A1 gene to outside databasesPrevious GC identifers: GC04P070020 GC04M070503 GC04M070704 GC04M070770 GC04M070635 |
Summaries for UGT2A1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for UGT2A1: The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyzebiotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase watersolubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination ofpotentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium,which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence,this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided byRefSeq, Nov 2011) UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1Function: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates areconjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance inthe conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active onodorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensoryepithelium Gene Wiki entry for UGT2A1
|
Genomic Views for UGT2A1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_022778.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the UGT2A1 gene promoter: POU2F2 (Oct-2.1) oct-B3 oct-B2 STAT5A Cdc5 POU2F2 POU2F2C POU2F1 POU2F1a POU2F2B Other transcription factors
Search SABiosciences Chromatin IP Primers for UGT2A1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT2A1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q13 Ensembl cytogenetic band: 4q13.3 HGNC cytogenetic band: 4q13UGT2A1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M070454: view genomic region
(about GC identifiers)
Start:
|
70,454,135 bp from pter |
End:
|
70,518,967 bp from pter |
Size:
|
64,833 bases |
Orientation:
|
minus strand |
|
Proteins for UGT2A1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1 (See
protein sequence)Recommended Name: UDP-glucuronosyltransferase 2A1 precursor Size: 527 amino acids; 59926 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Caution: According to HGNC, UGT2A1 and UGT2A2 are 2 separate genes. However, they share common exons at the C-terminus,suggesting that UGT2A1 and UGT2A2 are different isoforms encoded by the same locus
Secondary accessions: B4E2F4 D3GER1 D3GER2 E9PDM7 J3KNA3Alternative splicing: 5 isoforms: Q9Y4X1-1 Q9Y4X1-2 Q9Y4X1-3 Q9Y4X1-4 Q9Y4X1-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UGT2A1: NX_Q9Y4X1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y4X1 4/19 DME Specific Peptides for UGT2A1 (Q9Y4X1) (see all 19)
UGT2A1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001239203.1 NP_001239204.1 NP_006789.2 ENSEMBL proteins: ENSP00000424478 ENSP00000421432 ENSP00000425497 ENSP00000286604 ENSP00000427709 ENSP00000387888 Reactome Protein details: Q9Y4X1 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
UGT2A1 for ontologies About GeneDecksing
UGT2A1 Antibody Products: Assay Products for UGT2A1: |
Protein
Domains / Families for UGT2A1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UGT2A1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9Y4X1ProtoNet protein and cluster: Q9Y4X1 1 Blocks protein family: IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase
UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1Similarity: Belongs to the UDP-glycosyltransferase family |
Function for UGT2A1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1Function: UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates areconjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance inthe conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active onodorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensoryepitheliumCatalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronosideBiophysicochemical properties: Kinetic parameters: KM=75.4 uM for 3-hydroxybiphenyl; KM=59.5 uM for umbelliferone;KM=51.6 uM for S-(-)-b-citronellol; KM=170.1 uM for borneol; KM=56.2 uM for testosterone; KM=251 uM forUDP-glucuronate; Vmax=2.60 nmol/min/mg enzyme with 3-hydroxybiphenyl as substrate; Vmax=0.61 nmol/min/mg enzyme withumbelliferone as substrate; Vmax=1.98 nmol/min/mg enzyme with S-(-)-b-citronellol as substrate; Vmax=1.05 nmol/min/mgenzyme with borneol as substrate; Vmax=0.25 nmol/min/mg enzyme with testosterone as substrate; Genatlas biochemistry entry for UGT2A1:UDP glucoronosyltransferase 2 alpha 1,specific for the olfactory tissue Enzyme Number (IUBMB): EC 2.4.1.171 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT2A1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT2A1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UGT2A1 (NM_006798) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGT2A1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT2A1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2A1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0015020 | glucuronosyltransferase activity |
IEA | -- | | GO:0016758 | transferase activity, transferring hexosyl groups |
-- | -- |
UGT2A1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for UGT2A1:
|
Pathways & Interactions for UGT2A1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glucuronidation | | | 2 | Drug metabolism - cytochrome P450 | | | 3 | Biological oxidations | | | 4 | Metabolism | | | 5 | Pentose and glucuronate interconversions | |
Pathway sources See GeneCards unified pathways Show all pathways
2 BioSystems Pathways for UGT2A1 
4
Reactome Pathways for UGT2A1
5/11
Kegg Pathways (Kegg details for UGT2A1) (see all 11):
UGT2A1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UGT2A1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/56 Interacting proteins for UGT2A1 (ENSP000002866044) via UniProtKB, MINT, STRING, and/or I2D (see all 56)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
UGT2A1 for ontologies About GeneDecksing
|
Drugs & Compounds for UGT2A1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for UGT2A1
10/83 HMDB Compounds for UGT2A1 (see all 83) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| (23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide) | (23S)-23,25-dihydroxy-24-oxovitamin D3 23-(beta-glucuronide) (see all 5) | -- | -- | | 1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid | Ibuprofen acyl glucuronide;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[4-(2-methylpropyl)phenyl]propanoyloxy]oxane-2-carboxylic acid (see all 5) | 115075-59-7 | -- | | 1-Salicylate glucuronide | 1-salicylic acid glucuronide | -- | -- | | 11-Hydroxyprogesterone 11-glucuronide | 11-hydroxyprogesterone 11-glucuronoside (see all 5) | 77710-64-6 | -- | | 11-Oxo-androsterone glucuronide | 11-oxo-etiocholanolone glucuronide (see all 3) | -- | -- | | 11-beta-hydroxyandrosterone-3-glucuronide | 11-beta-hydroxyetiocholanolone-3-glucuronide | -- | -- | | 15-hydroxynorandrostene-3,17-dione glucuronide | 15-HNADG (see all 5) | 131749-23-0 | -- | | 16-alpha,17-beta-estriol 17-beta-D-glucuronide | estra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide (see all 7) | 7219-89-8 | -- | | 17-alpha-estradiol-3-glucuronide | | -- | -- | | 17-beta-estradiol glucuronide | | -- | -- | Search CenterWatch for drugs/clinical trials and news about UGT2A1 / UD2A1 
|
Transcripts for UGT2A1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for UGT2A1 gene (3 alternative transcripts): NM_001252274.1 NM_001252275.1 NM_006798.3 Unigene Cluster for UGT2A1: UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus Hs.225950 [show with all ESTs]Unigene Representative Sequence: NM_0012522748 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000503640(uc003hem.4 uc011caq.2 uc010ihu.3) ENST00000512704(uc010iht.3) ENST00000514019 ENST00000286604 ENST00000502343 ENST00000514341 ENST00000505512 ENST00000457664(uc010ihs.3 uc021xox.1)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT2A1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT2A1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UGT2A1 (NM_006798) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGT2A1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT2A1  |
Additional cDNA sequence: AJ006054.1 AK304249.1 AK314209.1 BC142640.1 FJ664272.1 FJ664273.1 2 DOTS entries: DT.92415436 DT.91913500 7 AceView cDNA sequences: BX283268 AJ006054 NM_006798 CD105882 BG400151 BG185464 BG186196 GeneLoc Exon Structure
|
Expression for UGT2A1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UGT2A1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: ATTATTATTA
About this image See UGT2A1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for UGT2A1
SOURCE GeneReport for Unigene cluster: Hs.225950 UniProtKB/Swiss-Prot: UD2A1_HUMAN, Q9Y4X1Tissue specificity: Olfactory epithelium and brain. Isoform 2 is mainly expressed in the nasal mucosa SABiosciences Expression via Pathway-Focused PCR Arrays including UGT2A1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGT2A1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UGT2A1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGT2A1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGT2A1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2A1 |
Orthologs for UGT2A1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for UGT2A1 gene from 1/9 species (see all 9) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.114192 |
Transcribed sequence with moderate similarity to protein more |
75.84(n) |
  |
CK028589.1 |
ENSEMBL Gene Tree for UGT2A1 (if available) TreeFam Gene Tree for UGT2A1 (if available)  |
Paralogs for UGT2A1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for UGT2A1 gene
- UGT1A82 UGT1A72 UGT3A12 UGT2B72 UGT2B112 UGT1A32 UGT1A12 UGT1A52
- UGT3A22 UGT2B102 UGT1A102 UGT1A62 UGT82 UGT2B152 UGT2B42 UGT2B172
- UGT2A32 UGT2B282 UGT1A92 UGT1A42
18/29 SIMAP similar genes for UGT2A1 using alignment to 3 protein entries: UD2A1_HUMAN (see all proteins)
(see all similar genes):UGT2A3 UGT2B11 UGT2B4 UGT2B17 UGT2B28 UGT2B15 UGT2B7 UGT2B10 UGT1A3S UGT1A9S UGT1A6 UGT1 UGT1A1 BILIQTL1 UGT1A8S UGT1A6S UGT1A10 UGT1A5
UGT2A1 for paralogs About GeneDecksing
|
Genomic Variants for UGT2A1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 16 variations for UGT2A1 15 CNVs: 92191 80359 92189 23048 22681 36292 80360 92188 7451 6276 53271 80358 36293 92190 63855 1 Indel: 80361 Human Gene Mutation Database (HGMD): UGT2A1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT2A1 |
|
Disorders
/ Diseases for UGT2A1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UGT2A1 for disorders About GeneDecksing
OMIM gene information: 604716
OMIM disorders: --
4 diseases for UGT2A1: About MalaCardskernicterus hearing loss fascioliasis cholesterol 3 diseases from the University of Copenhagen DISEASES database for UGT2A1:Fascioliasis Kernicterus Gilbert syndrome Human Genome Epidemiology (HuGE) Navigator: UGT2A1 (3 documents) Export disorders for UGT2A1 gene to outside databases
|
Publications for UGT2A1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UGT2A1 gene, integrated from 9 sources (see all 14): (articles sorted by number of sources associating them with UGT2A1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and characterization of a novel human olfactory UDP- glucuronosyltransferase. (PubMed id 10359671)1, 2, 3 Jedlitschky G.A.... Burchell B. (1999)
- Human UDP-glucuronosyltransferase UGT2A2: cDNA constr uction, expression, and functional characterization in comparison with UGT2A1 a nd UGT2A3. (PubMed id 19858781)1, 2 Sneitz N....Finel M. (2009)
- Identification and functional characterization of a no vel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in toba cco-related cancer susceptibility. (PubMed id 22984225)1 Bushey R.T. and Lazarus P. (2012)
- Characterization of UDP-glucuronosyltransferase 2A1 ( UGT2A1) variants and their potential role in tobacco carcinogenesis. (PubMed id 21164388)1 Bushey R.T....Lazarus P. (2011)
- Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1 Saito A....Kamatani N. (2009)
- Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1 Ross C.J....Hayden M.R. (2009)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. (PubMed id 16141793)1 Mackenzie P.I....Nebert D.W. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8. (PubMed id 12376738)1 Iida A....Nakamura Y. (2002)
|
External Searches for UGT2A1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing UGT2A1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UGT2A1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UGT2A1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for UGT2A1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UGT2A1 gene: Search GeneIP for patents involving UGT2A1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for UGT2A1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for UGT2A1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UGT2A1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGT2A1 | | OriGene Protein Over-expression Lysate for UGT2A1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for UGT2A1 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT2A1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT2A1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for UGT2A1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for UGT2A1 | | OriGene Custom Protein Services for UGT2A1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UGT2A1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT2A1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT2A1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UGT2A1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGT2A1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGT2A1 |
| |
 |  |  |  | |
| | | Search Tocris compounds for UGT2A1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | UGT2A1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT2A1 |
|  |  |  | | | ThermoFisher Antibody for UGT2A1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT2A1 |
|
|
|
|