UGT1A7 Gene
protein-coding GIFtS: 49
GCID: GC02P234581
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|
UDP glucuronosyltransferase 1 family, polypeptide A7(Previous names: UDP glycosyltransferase 1 family, polypeptide A6 )
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Aliases
for UGT1A7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| UDP Glucuronosyltransferase 1 Family, Polypeptide A71 2 | | UDP Glycosyltransferase 1 Family, Polypeptide A61 | | UGT1G1 2 3 | | UDPGT2 | | UGT-1G2 3 | | UDP Glycosyltransferase 1 Family, Polypeptide A72 | | UGT1-072 3 | | UDP-Glucuronosyltransferase 1 Family Polypeptide A7s2 | | UGT1.72 3 | | UDP-Glucuronosyltransferase 1-72 | | UDP-Glucuronosyltransferase 1-G2 3 | | GNT13 | | UDP-Glucuronosyltransferase 1A72 3 | | UGT13 | | UDPGT 1-72 3 | | UGT1*73 | | EC 2.4.1.173 8 | | |
Export aliases for UGT1A7 gene to outside databasesPrevious GC identifers: GC02U990247 GC02P234820 GC02P234883 GC02P234368 GC02P234372 GC02P234198 GC02P234209 GC02P234218 GC02P234255 GC02P226390 |
Summaries
for UGT1A7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UGT1A7:
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms smalllipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites.This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteenunique alternate first exons followed by four common exons. Four of the alternate first exons are consideredpseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteinswith different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulatedby its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: UD17_HUMAN, Q9HAW7Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobioticsand endogenous compounds
Gene Wiki entry for UGT1A7
|
Genomic Views
for UGT1A7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UGT1A7 gene promoter:
PPAR-gamma1 AP-1 ATF-2 COUP HNF-4alpha2 PPAR-gamma2 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for UGT1A7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT1A7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q37 Ensembl cytogenetic band: 2q37.1 HGNC cytogenetic band: 2q37UGT1A7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P234581: view genomic region
(about GC identifiers)
Start:
|
234,590,584 bp from pter |
End:
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234,681,945 bp from pter |
Size:
|
91,362 bases |
Orientation:
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plus strand |
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Proteins
for UGT1A7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UD17_HUMAN, Q9HAW7 (See
protein sequence)Recommended Name: UDP-glucuronosyltransferase 1-7 precursor Size: 530 amino acids; 59819 Da
Subcellular location: Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein (Potential)
Secondary accessions: O00473Alternative splicing: 1 isoform: Q9HAW7-1 Explore the universe of human proteins at neXtProt for UGT1A7: NX_Q9HAW7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HAW7
4/25 DME Specific Peptides for UGT1A7 (Q9HAW7) (see all 25)
UGT1A7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_061950.2
ENSEMBL proteins: ENSP00000362525 ENSP00000420181 Reactome Protein details: Q9HAW7
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
UGT1A7 for ontologies About GeneDecksing
UGT1A7 Antibody Products:
Assay Products for UGT1A7: |
Protein
Domains /
Families
for UGT1A7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UGT1A7 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9HAW7ProtoNet protein and cluster: Q9HAW7 2 Blocks protein families: IPB000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase
UniProtKB/Swiss-Prot: UD17_HUMAN, Q9HAW7Similarity: Belongs to the UDP-glycosyltransferase family |
Function
for UGT1A7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UD17_HUMAN, Q9HAW7Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobioticsand endogenous compoundsCatalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronosideEnzyme Number (IUBMB): EC 2.4.1.171 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT1A7
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT1A7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UGT1A7 (NM_019077) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGT1A7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT1A7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT1A7 |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
UGT1A7 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for UGT1A7:
|
Pathways & Interactions
for UGT1A7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Glucuronidation | | | 2 | Drug metabolism - cytochrome P450 | | | 3 | Biological oxidations | | | 4 | Metabolism | | | 5 | Pentose and glucuronate interconversions | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for UGT1A7
4 
Reactome Pathways for UGT1A7
1  PharmGKB Pathway for UGT1A7
11 
Kegg Pathways (Kegg details for UGT1A7) (see first 5):
UGT1A7 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UGT1A7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/56 Interacting proteins for UGT1A7 (ENSP000003625254) via UniProtKB, MINT, STRING, and/or I2D (see all 56)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
UGT1A7 for ontologies About GeneDecksing
|
Drugs & Compounds
for UGT1A7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
UGT1A7 for compounds About GeneDecksing
 Browse Tocris compounds for UGT1A7
10/84 HMDB Compounds for UGT1A7 (see all 84) About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Ethyl glucuronide | | 17685-04-0 | 16139098 | | (23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide) | (23S)-23,25-dihydroxy-24-oxovitamin D3 23-(beta-glucuronide) (see all 5) | -- | -- | | 1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid | Ibuprofen acyl glucuronide;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[4-(2-methylpropyl)phenyl]propanoyloxy]oxane-2-carboxylic acid (see all 5) | 115075-59-7 | -- | | 1-Salicylate glucuronide | 1-salicylic acid glucuronide | -- | -- | | 11-Hydroxyprogesterone 11-glucuronide | 11-hydroxyprogesterone 11-glucuronoside (see all 5) | 77710-64-6 | -- | | 11-Oxo-androsterone glucuronide | 11-oxo-etiocholanolone glucuronide (see all 3) | -- | -- | | 11-beta-hydroxyandrosterone-3-glucuronide | 11-beta-hydroxyetiocholanolone-3-glucuronide | -- | -- | | 15-hydroxynorandrostene-3,17-dione glucuronide | 15-HNADG (see all 5) | 131749-23-0 | -- | | 16-alpha,17-beta-estriol 17-beta-D-glucuronide | estra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide (see all 7) | 7219-89-8 | -- | | 17-alpha-estradiol-3-glucuronide | | -- | -- |
10/21 Novoseek chemical compound relationships for UGT1A7 gene (see all 21) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| uridine diphosphate |
80 |
4 |
16724991 (1), 12669388 (1), 16097053 (1) |
| sn 38 |
79.4 |
4 |
12944498 (2), 18349289 (2) |
| sn38 glucuronide |
76.2 |
3 |
18418374 (1), 12181437 (1) |
| glucuronide |
73.4 |
2 |
9762354 (1), 11560872 (1) |
| n-hydroxy phip |
70.7 |
3 |
15310245 (1), 11375903 (1) |
| irinotecan |
66.5 |
15 |
18349289 (3), 15709193 (2), 12944498 (2), 19712005 (2) (see all 9) |
| glucuronic acid |
59.8 |
2 |
16159430 (1) |
| flavopiridol |
59.3 |
1 |
12944498 (1) |
| uridine |
58.8 |
3 |
17529886 (1), 16636344 (1), 17436274 (1) |
| mycophenolic acid |
53 |
7 |
17529886 (5), 18695635 (1) |
1 PharmGKB related drug/compound annotation for UGT1A7 geneAbout this table
Search CenterWatch for drugs/clinical trials and news about UGT1A7 / UD17
|
Transcripts
for UGT1A7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UGT1A7 gene: NM_019077.2 2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000373426(uc010zmx.1 uc002vut.3) ENST00000485022
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT1A7
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT1A7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UGT1A7 (NM_019077) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGT1A7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT1A7 |
24/271 AceView cDNA sequences (see all 271): BE464186 BM829535 NM_021027 BE464379 AY435137 AY435136 NM_001072 AY435142 NM_019077 AY435138 NM_000463 NM_019075 NM_019076 CB163341 AU076863 BG165230 BI764371 NM_007120 AY435143 BC043491 AY435144 NM_205862 AY435141 AI767337
GeneLoc Exon Structure
|
Expression
for UGT1A7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UGT1A7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See UGT1A7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UGT1A7
UniProtKB/Swiss-Prot: UD17_HUMAN, Q9HAW7Tissue specificity: Liver and gastric tissue
SABiosciences Custom PCR Arrays for UGT1A7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGT1A7
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat UGT1A7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGT1A7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGT1A7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT1A7 |
Orthologs
for UGT1A7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for UGT1A7 gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for UGT1A7 (if available)
TreeFam Gene Tree for UGT1A7 (if available) |
Paralogs
for UGT1A7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UGT1A7 gene
- UGT1A81 2 UGT1A101 2 UGT1A91 2 UGT2A22 UGT3A12 UGT2B72 UGT2B112 UGT1A32
- UGT1A12 UGT1A52 UGT3A22 UGT2B102 UGT1A62 UGT82 UGT2B152 UGT2B42
- UGT2B172 UGT2A32 UGT2B282 UGT1A42
18/30 SIMAP similar genes for UGT1A7 using alignment to 16 protein entries: UD17_HUMAN (see all proteins)
(see all similar genes):UGT1G UGT1A8S UGT1A9S UGT1A10 UGT1J UGT1A8
UGT1A3S UGT1H UGT1A9 UGT1A6 UGT1A6S UGT2B17
BILIQTL1 UGT1A1 UGT1 UGT2B28 UGT2B11 UGT1A4S
UGT1A7 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for UGT1A7
PGOHUM00000241145 PGOHUM00000241146
|
Genomic Variants
for UGT1A7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: UD17_HUMAN, Q9HAW7Polymorphism: There are four common allelic UGT1A7 variants which exhibit significant differences in catalytic activitytowards 3-, 7-, and 9-hydroxy-benzo(a)pyrene. UGT1A7*3 exhibits a 5.8-fold lower relative Vmax compared to UGT1A7*1,whereas UGT1A7*2 and UGT1A7*4 have a 2.6- and 2.8-fold lower relative Vmax than UGT1A7*1, respectively, suggestingthat these mutations confer slow glucuronidation phenotype
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for UGT1A7
10 CNVs: 90342 90341 61892 35795 50416 39282 37520 39281 63332 90340
Human Gene Mutation Database (HGMD): UGT1A7
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT1A7 |
|
Disorders
/ Diseases
for UGT1A7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UGT1A7 for disorders About GeneDecksing
OMIM gene information: 606432
OMIM disorders: --
20/29  diseases for UGT1A7 (see all 29): About MalaCardsgilbert syndrome neonatal jaundice drug dependence orolaryngeal cancer
kernicterus hearing loss hepatitis c hepatitis b
liver cirrhosis pancreatitis hepatocellular carcinoma pandas
jaundice pancreatic diseases neutropenia pancreatic cancer
colorectal cancer crohn's disease hepatitis liver disease
1 disease from the University of Copenhagen DISEASES database for UGT1A7:Bilirubin metabolic disorder 10/15 Novoseek disease relationships for UGT1A7 gene (see all 15) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gilberts syndrome |
74.9 |
5 |
18349289 (3), 19303655 (1), 17850628 (1) |
| pancreatic diseases |
49.6 |
2 |
12806614 (1), 16199544 (1) |
| hyperbilirubinemia |
36.2 |
1 |
19303655 (1) |
| hepatocellular carcinoma |
35.3 |
16 |
11677206 (3), 18271934 (3), 15073122 (2), 15382168 (1) (see all 8) |
| colorectal cancer |
33.5 |
12 |
16620591 (4), 12010889 (1), 15709193 (1), 19364970 (1) (see all 6) |
| chronic pancreatitis |
32.3 |
4 |
16199544 (2), 12806614 (1), 17325733 (1) |
| genetic susceptibility |
15.1 |
3 |
16159430 (2), 16724991 (1) |
| cancer |
13 |
7 |
11677206 (2), 17406868 (2), 12010889 (1), 16620591 (1) (see all 5) |
| hepatitis c |
12.8 |
4 |
11343231 (1), 18054330 (1), 15073122 (1), 16086712 (1) |
| pancreatic cancer |
12.8 |
7 |
16199544 (4), 17072959 (2), 12806614 (1) |
Genetic Association Database (GAD): UGT1A7
Human Genome Epidemiology (HuGE) Navigator: UGT1A7 (57 documents)
Export disorders for UGT1A7 gene to outside databases
|
Publications
for UGT1A7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UGT1A7 gene, integrated from 9 sources (see all 150):
(articles sorted by number of sources associating them with UGT1A7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. (PubMed id 11434514)1, 2, 3, 9 Gong Q.H....Popescu N.C. (2001)
- Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancer. (PubMed id 16030093)1, 4, 9 Butler L.M....Guillemette C. (2005)
- UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma risk and onset age. (PubMed id 16086712)1, 4, 9 Tseng C.S....Huang C.S. (2005)
- Polymorphisms of uridine-diphosphoglucuronosyltransferase 1A7 gene in Taiwan Chinese. (PubMed id 15682470)1, 4, 9 Huang M.J....Huang C.S. (2005)
- Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene. (PubMed id 11037804)1, 2, 9 Guillemette C.... Housman D.E. (2000)
- Polymorphisms of UDP-glucuronosyltransferase 1A7 are not involved in pancreatic diseases. (PubMed id 16199544)1, 4, 9 Verlaan M....Witt H. (2005)
- Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer. (PubMed id 12010889)1, 4, 9 Strassburg C.P....Manns M.P. (2002)
- [Correlation of polymorphisms of UDP-glucuronosyltransferase 1A7 gene to genetic susceptibility of lung cancer] (PubMed id 16159430)1, 4, 9 Feng F.Y....Lin D.X. (2005)
- UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma in japanese patients with hepatitis C virus infection. (PubMed id 15073122)1, 4, 9 Wang Y....Omata M. (2004)
- UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer. (PubMed id 12806614)1, 4, 9 Ockenga J....Strassburg C.P. (2003)
|
External Searches for UGT1A7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UGT1A7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UGT1A7 gene
(According to HUGE)
About This Section
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Specialized Databases showing UGT1A7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for UGT1A7 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for UGT1A7 gene:
Search GeneIP for patents involving UGT1A7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for UGT1A7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UGT1A7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UGT1A7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGT1A7 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UGT1A7 | | OriGene 3'-UTR Clone for UGT1A7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGT1A7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGT1A7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UGT1A7 | | OriGene Custom Protein Services for UGT1A7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UGT1A7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGT1A7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT1A7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UGT1A7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGT1A7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGT1A7 |
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| | | | Search Tocris compounds for UGT1A7 |
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 | | | UGT1A7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT1A7 |
|  |  |  | | | | Search ThermoFisher Antibodies for UGT1A7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGT1A7 |
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