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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

UGT1A10 Gene

protein-coding GIFtS: 51
GCID: GC02P234545

UDP glucuronosyltransferase 1 family, polypeptide A10

(Previous names: UDP glycosyltransferase 1 family, polypeptide A10 )

Explore 14 diseases affiliated with
UGT1A10 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UDP Glucuronosyltransferase 1 Family, Polypeptide A10¹ ²		UDPGT 1-10² ³
UGT1J¹ ² ³		EC 2.4.1.17³ ⁸
UDP Glycosyltransferase 1 Family, Polypeptide A10¹ ²		UDPGT²
UGT-1J² ³		UDP-Glucuronosyltransferase 1-10²
UGT1-10² ³		GNT1³
UGT1.10² ³		UGT1³
UDP-Glucuronosyltransferase 1-J² ³		UGT1*10³
UDP-Glucuronosyltransferase 1A10² ³

External Ids:	HGNC: 12531¹	Entrez Gene: 54575²	Ensembl: ENSG00000242515⁷	OMIM: 606435⁵	UniProtKB: Q9HAW8³

Export aliases for UGT1A10 gene to outside databases

Previous GC identifers: GC02U990246 GC02P234814 GC02P234877 GC02P234327 GC02P234192 GC02P234202 GC02P234211 GC02P234222 GC02P234226 GC02P226345

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UGT1A10:

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small

lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites.

This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen

unique alternate first exons followed by four common exons. Four of the alternate first exons are considered

pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins

with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated

by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and

quinolines. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: UD110_HUMAN, Q9HAW8

Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics

and endogenous compounds

Gene Wiki entry for UGT1A10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the UGT1A10 gene promoter:
TBP SRF TFIID SRF (504 AA) c-Myb LCR-F1 GATA-1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for UGT1A10

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGT1A10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37 Ensembl cytogenetic band: 2q37.1 HGNC cytogenetic band: 2q37

UGT1A10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UGT1A10 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P234545: view genomic region (about GC identifiers)

Start:	234,545,100 bp from pter	End:	234,681,951 bp from pter
Size:	136,852 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UD110_HUMAN, Q9HAW8 (See protein sequence)

Recommended Name: UDP-glucuronosyltransferase 1-10 precursor

Size: 530 amino acids; 59810 Da

Subcellular location: Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein (Potential)

Secondary accessions: O00474 Q6NT91

Alternative splicing: 1 isoform: Q9HAW8-1

Explore the universe of human proteins at neXtProt for UGT1A10: NX_Q9HAW8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9HAW8

4/24 DME Specific Peptides for UGT1A10 (Q9HAW8) (see all 24)

PEVSWQL

FWVEFVM

WLLRTDF

QYHSLDV

UGT1A10 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_061948.1

ENSEMBL proteins:

ENSP00000343838 ENSP00000362544

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	Uscn Proteins for UGT1A10

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005783	endoplasmic reticulum	IDA	18556656
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0005792	microsome	--	--
GO:0016021	integral to membrane	IEA	--

UGT1A10 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UGT1A10 for domains About GeneDecksing

1 InterPro domain/family:

IPR002213 UDP_glucos_trans

Graphical View of Domain Structure for InterPro Entry Q9HAW8

ProtoNet protein and cluster: Q9HAW8

1 Blocks protein family: IPB002213 UDP-glucoronosyl/UDP-glucosyl transferase

UniProtKB/Swiss-Prot: UD110_HUMAN, Q9HAW8

Similarity: Belongs to the UDP-glycosyltransferase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: UD110_HUMAN, Q9HAW8

Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics

and endogenous compounds

Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside

Enzyme Number (IUBMB): EC 2.4.1.17¹ ²

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGT1A10

Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001972	NOT retinoic acid binding	IDA	--
GO:0005080	protein kinase C binding	IPI	18556656
GO:0015020	glucuronosyltransferase activity	IDA	--
GO:0016758	transferase activity, transferring hexosyl groups	--	--
GO:0019899	enzyme binding	IDA	--

UGT1A10 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Glucuronidation

Glucuronidation	1.00	Other types of O-glycan biosynthesis	0.36
Starch and sucrose metabolism	0.42	Drug metabolism - other enzymes	0.32
Porphyrin and chlorophyll metabolism	0.38

Irinotecan Pathway, Pharmacokinetics

	Irinotecan Pathway, Pharmacokinetics	1.00			Irinotecan Pathway, Pharmacodynamics	0.50
	Irinotecan Pathway	0.73			Mycophenolic acid Pathway, Pharmacokinetics	0.50

Tamoxifen metabolism

	Tamoxifen metabolism	1.00			Estradiol metabolism	0.52
	Tamoxifen Pathway, Pharmacokinetics	0.68			Estradiol metabolism	0.52

Drug metabolism - cytochrome P450

	Drug metabolism - cytochrome P450	1.00			Retinol metabolism	0.40
	Metabolism of xenobiotics by cytochrome P450	0.73

superpathway of melatonin degradation

superpathway of melatonin degradation

1.00

melatonin degradation I

0.85

Pathway sources
See GeneCards unified pathways
Show all pathways

3 EMD Millipore Pathways for UGT1A10

	Estradiol metabolism
	Acetaminophen metabolism
	Benzo[a]pyrene metabolism

3 GeneGo (Thomson Reuters) Pathways for UGT1A10

	Estradiol metabolism
	Benzo[a]pyrene metabolism
	Acetaminophen metabolism

5/10 BioSystems Pathways for UGT1A10 (see all 10)

	Irinotecan Pathway
	Glucuronidation
	thyroid hormone metabolism II (via conjugation and/or degradation)
	serotonin degradation
	nicotine degradation IV

5 PharmGKB Pathways for UGT1A10

	Irinotecan Pathway, Pharmacodynamics
	Irinotecan Pathway, Pharmacokinetics
	Mycophenolic acid Pathway, Pharmacokinetics
	Tamoxifen Pathway, Pharmacokinetics
	Valproic Acid Pathway, Pharmacokinetics

5/11 Kegg Pathways (Kegg details for UGT1A10) (see all 11):

	Pentose and glucuronate interconversions
	Ascorbate and aldarate metabolism
	Steroid hormone biosynthesis
	Starch and sucrose metabolism
	Other types of O-glycan biosynthesis

UGT1A10 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for UGT1A10

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/56 Interacting proteins for UGT1A10 (ENSP00000343838⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 56)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ADH1B	ENSP00000306606⁴	STRING: ENSP00000306606
ADH4	ENSP00000265512⁴	STRING: ENSP00000265512
AKR1C4	ENSP00000263126⁴	STRING: ENSP00000263126
BLVRA	ENSP00000265523⁴	STRING: ENSP00000265523
CES2	ENSP00000317842⁴	STRING: ENSP00000317842

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008152	metabolic process	NAS	--
GO:0051552	flavone metabolic process	IDA	18052087
GO:0052695	cellular glucuronidation	IDA	--

UGT1A10 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

UGT1A10 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UGT1A10

10/84 HMDB Compounds for UGT1A10 (see all 84) About this table

Compound	Synonyms	CAS #	PubMed Ids
Ethyl glucuronide		17685-04-0	16139098
(23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)	(23S)-23,25-dihydroxy-24-oxovitamin D3 23-(beta-glucuronide) (see all 5)	--	--
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid	Ibuprofen acyl glucuronide;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[4-(2-methylpropyl)phenyl]propanoyloxy]oxane-2-carboxylic acid (see all 5)	115075-59-7	--
1-Salicylate glucuronide	1-salicylic acid glucuronide	--	--
11-Hydroxyprogesterone 11-glucuronide	11-hydroxyprogesterone 11-glucuronoside (see all 5)	77710-64-6	--
11-Oxo-androsterone glucuronide	11-oxo-etiocholanolone glucuronide (see all 3)	--	--
11-beta-hydroxyandrosterone-3-glucuronide	11-beta-hydroxyetiocholanolone-3-glucuronide	--	--
15-hydroxynorandrostene-3,17-dione glucuronide	15-HNADG (see all 5)	131749-23-0	--
16-alpha,17-beta-estriol 17-beta-D-glucuronide	estra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide (see all 7)	7219-89-8	--
17-alpha-estradiol-3-glucuronide		--	--

4 DrugBank Compounds for UGT1A10 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Etodolac	--	41340-25-4	enzyme	substrate	19515014
Losartan	DUP 89 (see all 2)	114798-26-4	enzyme	substrate	19515014
Mycophenolate mofetil	--	128794-94-5	enzyme	substrate	11817210
Troglitazone	--	97322-87-7	enzyme	substrate	12433820

10/13 Novoseek chemical compound relationships for UGT1A10 gene (see all 13) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
udp glucuronic acid	78.7	1	18048489 (1)
uridine diphosphate	77.2	1	18161889 (1)
n-hydroxy phip	76.2	2	11375903 (1)
glucuronide	63.8	1	11560872 (1)
imipramine	49.1	1	12019188 (1)
mycophenolic acid	42.6	4	9325166 (3), 15039300 (1)
orthophosphate	41.2	2	15845768 (1), 15117964 (1)
cotinine	34.8	2	12433823 (1), 12167564 (1)
propofol	34	1	12386132 (1)
curcumin	32.3	1	15845768 (1)

1 PharmGKB related drug/compound annotation for UGT1A10 gene

Drug/compound	PharmGKB Annotation
valproic acid	CA

About this table

Search CenterWatch for drugs/clinical trials and news about UGT1A10 / UD110

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for UGT1A10 gene:

NM_019075.2

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000344644(uc002vur.3) ENST00000373445

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24/271 AceView cDNA sequences (see all 271):

BE463503 AK025403 BC053576 AU076863 NM_205862 BC043491 BI764371 AY435144

AI913618 AV660038 AY435140 AI795931 AY435143 NM_019075 CB157019 AY435138

AV646429 NM_019077 AY435142 NM_019078 BE464422 NM_019076 NM_001072 AI478649

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

UGT1A10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
See UGT1A10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UGT1A10

UniProtKB/Swiss-Prot: UD110_HUMAN, Q9HAW8

Tissue specificity: Liver and colon

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for UGT1A10 gene from 3/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	F1P1M7_CHICK⁶ -- (see all 5)	Uncharacterized protein (see all 5)	58(a) 46(a) (see all 5)	possible ortholog possible ortholog (see all 5)	7(5795449-5817899) 7(5844610-5845328)
lizard (Anolis carolinensis)	Reptilia	-- UGT1A6⁶ (see all 3)	--	55(a) 41(a) (see all 3)	possible ortholog possible ortholog (see all 3)	1(118894319-118901649) 1(118848249-118849106)
zebrafish (Danio rerio)	Actinopterygii	ugt1ab⁶ ugt1b4⁶	UDP glucuronosyltransferase 1 family a, b UDP glucuronosyltransferase 1 family, polypeptide ...	50(a) 45(a)	many ↔ many many ↔ many	9(10194767-10228512) 11(31171792-31204741)

ENSEMBL Gene Tree for UGT1A10 (if available)
TreeFam Gene Tree for UGT1A10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for UGT1A10 gene

UGT1A8¹ ² UGT1A7¹ ² UGT1A9¹ ² UGT2A2² UGT3A1² UGT2B7² UGT2B11² UGT1A3²

UGT1A1² UGT1A5² UGT3A2² UGT2B10² UGT1A6² UGT8² UGT2B15² UGT2B4²

UGT2B17² UGT2A3² UGT2B28² UGT1A4²

18/30 SIMAP similar genes for UGT1A10 using alignment to 3 protein entries: UD110_HUMAN (see all proteins) (see all similar genes):

UGT1J UGT1A9S UGT1A8S UGT1A8 UGT1A9 UGT1A3S

UGT1H UGT1A7 UGT1G UGT1A6 BILIQTL1 UGT1A6S

UGT1A1 UGT1A4S UGT2A3 UGT1A4 UGT2B7 UGT2B15

UGT1A10 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for UGT1A10
PGOHUM00000259940

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for UGT1A10
11 CNVs: 90342 90341 61892 35795 50416 39282 37520 39281 63332 90340 63331
Human Gene Mutation Database (HGMD): UGT1A10

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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UGT1A10 for disorders           About GeneDecksing

OMIM gene information: 606435    OMIM disorders: --

14 diseases for UGT1A10:    About MalaCards

familial adenomatous polyposis neonatal jaundice drug dependence kernicterus

hearing loss polyposis jaundice colon cancer

duodenitis liver disease lung cancer cholesterol

hepatitis carcinoma

2 Novoseek disease relationships for UGT1A10 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
colon cancer	24.2	1	16620709 (1)
cancer	0	10	16510539 (3), 20007297 (1)

Genetic Association Database (GAD): UGT1A10
Human Genome Epidemiology (HuGE) Navigator: UGT1A10 (15 documents)

Export disorders for UGT1A10 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for UGT1A10 gene, integrated from 9 sources (see all 109):
(articles sorted by number of sources associating them with UGT1A10)

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Three novel single nucleotide polymorphisms in UGT1A10. (PubMed id 15618702)^{1, 2, 9} Saeki M.... Sawada J. (2002)
The human UDP glucuronosyltransferase, UGT1A10, glucu ronidates mycophenolic acid. (PubMed id 9325166)^{1, 3, 9} Mojarrabi B. and Mackenzie P.I. (1997)
Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4. (PubMed id 15057901)^{1, 4, 9} Ehmer U....Strassburg C.P. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Detection of UGT1A10 polymorphisms and their association with orolaryngeal carcinoma risk. (PubMed id 12910533)^{1, 4} Elahi A....Lazarus P. (2003)
Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus. (PubMed id 11434514)^{1, 2} Gong Q.H....Popescu N.C. (2001)
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. (PubMed id 9295054)^{1, 3} Mackenzie P.I....Nebert D.W. (1997)
Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue. (PubMed id 9271343)^{1, 2} Strassburg C.P.... Tukey R.H. (1997)
UDP-glucuronosyltransferase 1A10: activity against th e tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in canc er susceptibility. (PubMed id 20007297)^{1, 9} Balliet R.M....Lazarus P. (2010)
Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. (PubMed id 15117964)^{1, 9} Basu N.K....Owens I.S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54575	HGNC: 12531	AceView: UGT1A1	Ensembl:ENSG00000242515	euGenes: HUgn54575
ECgene: UGT1A10	Kegg: 54575	H-InvDB: UGT1A10

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for UGT1A10	Pharmacogenomics, SNPs, Pathways

Intellectual Property for UGT1A10 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for UGT1A10 gene:
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UGT1A10 Gene

UDP glucuronosyltransferase 1 family, polypeptide A10

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UGT1A10 Gene

UDP glucuronosyltransferase 1 family, polypeptide A10

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