Aliases for UGGT2 Gene
External Ids for UGGT2 Gene
Previous HGNC Symbols for UGGT2 Gene
Previous GeneCards Identifiers for UGGT2 Gene
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
GeneCards Summary for UGGT2 Gene
UGGT2 (UDP-Glucose Glycoprotein Glucosyltransferase 2) is a Protein Coding gene. Among its related pathways are Calnexin/calreticulin cycle and Protein processing in endoplasmic reticulum. GO annotations related to this gene include transferase activity, transferring glycosyl groups and UDP-glucose:glycoprotein glucosyltransferase activity. An important paralog of this gene is UGGT1.
UniProtKB/Swiss-Prot for UGGT2 Gene
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation (By similarity).