UGGT1 Gene
protein-coding GIFtS: 60
GCID: GC02P128848
|
|
UDP-glucose glycoprotein glucosyltransferase 1(Previous name: UDP-glucose ceramide glucosyltransferase-like 1 )
(Previous symbol: UGCGL1)
| |
Aliases
for UGGT1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| UDP-Glucose Glycoprotein Glucosyltransferase 11 2 | | EC 2.4.1.-3 | | UGCGL11 2 3 | | GT3 | | UDP-Glucose Ceramide Glucosyltransferase-Like 11 2 3 | | UGGT3 | | HUGT11 2 5 | | UGTR3 | | UGT12 3 | | HUGT11 2 5 | | UDP--Glc:Glycoprotein Glucosyltransferase2 3 | | EC 2.4.18 | | UDP-Glucose:Glycoprotein Glucosyltransferase 12 | | |
| External Ids: | HGNC: 156631 | Entrez Gene: 568862 | Ensembl: ENSG000001367317 | OMIM: 6058975 | UniProtKB: Q9NYU23 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n407958 | |
Export aliases for UGGT1 gene to outside databasesPrevious GC identifers: GC02P128566 GC02P121155
Summaries
for UGGT1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UGGT1:
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) thatselectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of theER.(supplied by OMIM, Oct 2009)
UniProtKB/Swiss-Prot: UGGG1_HUMAN, Q9NYU2Function: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded partof the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylatedproteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation
|
Genomic Views
for UGGT1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for UGGT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for UGGT1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGGT1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q14.3 Ensembl cytogenetic band: 2q14.3 HGNC cytogenetic band: 2q14.3UGGT1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P128848: view genomic region
(about GC identifiers)
Start:
|
128,848,754 bp from pter |
End:
|
128,953,251 bp from pter |
Size:
|
104,498 bases |
Orientation:
|
plus strand |
|
Proteins
for UGGT1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UGGG1_HUMAN, Q9NYU2 (See
protein sequence)Recommended Name: UDP-glucose:glycoprotein glucosyltransferase 1 precursor Size: 1555 amino acids; 177190 Da
Cofactor: Calcium or manganese
Subunit: Monomer as well as in a tight complex with SEP15 (By similarity)
Subcellular location: Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment
Sequence caution: Sequence=AAY14885.1; Type=Erroneous gene model prediction; Sequence=BAB14632.1; Type=Erroneousinitiation;
Secondary accessions: Q53QP2 Q53SL3 Q8IW30 Q9H8I4Alternative splicing: 2 isoforms: Q9NYU2-1 Q9NYU2-2 Explore the universe of human proteins at neXtProt for UGGT1: NX_Q9NYU2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NYU2
4/20 DME Specific Peptides for UGGT1 (Q9NYU2) (see all 20)
UGGT1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_064505.1
ENSEMBL proteins: ENSP00000400426 ENSP00000392701 ENSP00000365913 ENSP00000259253 ENSP00000389441 ENSP00000365158 Reactome Protein details: Q9NYU2
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005783 | endoplasmic reticulum |
IDA | 10694380 | | GO:0005788 | endoplasmic reticulum lumen |
TAS | -- | | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
ISS | -- |
UGGT1 for ontologies About GeneDecksing
UGGT1 Antibody Products:
Assay Products for UGGT1: |
Protein
Domains /
Families
for UGGT1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UGGT1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NYU2ProtoNet protein and cluster: Q9NYU2 1 Blocks protein family: IPB009448 UDP-glucose:Glycoprotein Glucosyltransferase
UniProtKB/Swiss-Prot: UGGG1_HUMAN, Q9NYU2Domain: The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects(By similarity)Similarity: Belongs to the glycosyltransferase 8 family |
Function
for UGGT1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UGGG1_HUMAN, Q9NYU2Function: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded partof the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylatedproteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradationInduction: By tunicamycin and A23187. Induced 3-4 fold 10 hours after treatmentEnzyme Numbers (IUBMB): EC 2.4.12 EC 2.4.1.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGGT1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGGT1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UGGT1 (NM_020120) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGGT1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGGT1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGGT1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
UGGT1 for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for UGGT1:
|
Pathways & Interactions
for UGGT1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Calnexin/calreticulin cycle | | | 2 | Asparagine N-linked glycosylation | | | 3 | Protein processing in endoplasmic reticulum | | | 4 | Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  GeneGo (Thomson Reuters) Pathway for UGGT1
5/6 
Reactome Pathways for UGGT1 (see all 6)
1 
Kegg Pathway (Kegg details for UGGT1):
UniProtKB/Swiss-Prot: UGGG1_HUMAN, Q9NYU2Pathway: Protein modification; protein glycosylation
UGGT1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UGGT1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/43 Interacting proteins for UGGT1 (Q9NYU23 ENSP000002592534) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006457 | protein folding |
TAS | -- | | GO:0018279 | protein N-linked glycosylation via asparagine |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- | | GO:0051084 | 'de novo' posttranslational protein folding |
TAS | 10694380 |
UGGT1 for ontologies About GeneDecksing
|
Drugs & Compounds
for UGGT1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
UGGT1 for compounds About GeneDecksing
 Browse Tocris compounds for UGGT1
2 HMDB Compounds for UGGT1 About this table
3 Novoseek chemical compound relationships for UGGT1 gene About this table
Search CenterWatch for drugs/clinical trials and news about UGGT1 / UGGG1
|
Transcripts
for UGGT1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UGGT1 gene (2 alternative transcripts): NM_001025777.1 NM_020120.3 Unigene Cluster for UGGT1: UDP-glucose glycoprotein glucosyltransferase 1 Hs.743306 [show with all ESTs]Unigene Representative Sequence: NR_0276718 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000430075 ENST00000438277(uc010fme.1) ENST00000376723 ENST00000259253
ENST00000488439 ENST00000418197 ENST00000465836 ENST00000375990(uc002tps.3 uc002tpr.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGGT1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGGT1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UGGT1 (NM_020120) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UGGT1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGGT1 |
Additional cDNA sequence: AF227905.1 AK023240.1 AK023671.1 AK074251.1 AK074376.1 AK293066.1 AK309101.1 BC041098.1 BC047727.1 NR_027671.2 16 DOTS entries: DT.408761 DT.100790543 DT.422860 DT.40279255 DT.105982 DT.95156634 DT.101974259 DT.92008224 DT.100737979 DT.120984571 DT.305778 DT.91742067 DT.92002021 DT.92427719 DT.95155165 DT.95265020 24/182 AceView cDNA sequences (see all 182): BQ932226 AA554920 BP359091 AA279242 AA926726 AW135426 CB152902 CB215567 BC047727 AF227905 BF592808 AI080983 AI655525 AA279123 AA810550 AA847178 BE550513 BX475218 AU132160 AI655867 CD106217 BU623794 BM040793 AW002565
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for UGGT1 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 21 | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38a | · | 38b | ^ | 39 | ^ | 40 | ^ | 41a | · | 41b | · | 41c | · | 41d | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 42a | · | 42b | ^ | 43a | · | 43b | · | 43c |
|---|
|
| SP1: | - | | | | | | | | | | |
| SP2: | - | | | | | | | | | | |
| SP3: | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for UGGT1
|
Expression
for UGGT1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UGGT1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTCCAACC
About this image
See UGGT1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UGGT1
SOURCE GeneReport for Unigene cluster: Hs.743306
UniProtKB/Swiss-Prot: UGGG1_HUMAN, Q9NYU2Tissue specificity: Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart
SABiosciences Expression via Pathway-Focused PCR Arrays including UGGT1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGGT1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UGGT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGGT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGGT1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGGT1 |
Orthologs
for UGGT1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UGGT1 gene from 7/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
UGGT11 |
UDP-glucose glycoprotein glucosyltransferase 1 |
78.49(n)
85.84(a) |
|
424757 XM_422579.3 XP_422579.3 |
lizard
(Anolis carolinensis) |
Reptilia |
UGGT16 |
-- |
85(a) |
1 ↔ 1 |
3(36414884-36468901) |
zebrafish
(Danio rerio) |
Actinopterygii |
BG304166.12 |
-- |
79.58(n) |
|
BG304166.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Ugt1 |
UDP-glucose-glycoprotein glucosyltransferase |
51.17(n)
45.75(a) |
|
40055 NM_079427.2 NP_524151.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
uggt-16uggt-26 |
-- |
42(a)37(a) |
many ↔ manymany ↔ many |
X(7495640-7500939) I(9317728-9327204) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
EBS11 |
UDP-glucose:glycoprotein glucosyltransferase |
48.32(n)
39.22(a) |
|
843462 NM_105791.4 NP_177278.3 |
rice
(Oryza sativa) |
Liliopsida |
Os.59002 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
73.73(n) |
|
AK059298.1 |
ENSEMBL Gene Tree for UGGT1 (if available)
TreeFam Gene Tree for UGGT1 (if available) |
Paralogs
for UGGT1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UGGT1 gene
- UGGT22
1 SIMAP similar gene for UGGT1 using alignment to 6 protein entries: UGGG1_HUMAN (see all proteins):UGGT2
UGGT1 for paralogs About GeneDecksing
|
Genomic Variants
for UGGT1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UGGT1 (128848754 - 128953251 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for UGGT1
7 Indels: 61818 45851 42110 58916 26436 40359 97974
1 Inversion: 37211 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGGT1 |
|
Disorders
/ Diseases
for UGGT1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UGGT1 for disorders About GeneDecksing
OMIM gene information: 605897
OMIM disorders: --
3  diseases for UGGT1: About MalaCardsdysentery sleeping sickness hepatitis
Export disorders for UGGT1 gene to outside databases
|
Publications
for UGGT1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UGGT1 gene, integrated from 9 sources (see all 42):
(articles sorted by number of sources associating them with UGGT1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity. (PubMed id 10694380)1, 2, 3, 9 Arnold S.M.... Kaufman R.J. (2000)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The noncatalytic portion of human UDP-glucose: glycoprotein glucosyltransferase I confers UDP-glucose binding and transferase function to the catalytic domain. (PubMed id 12913004)1, 9 Arnold S.M. and Kaufman R.J. (2003)
- The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin. (PubMed id 20498017)1, 9 Pearse B.R....Hebert D.N. (2010)
- Identification of HUGT1 as a potential BiP activator and a cellular target for improvement of recombinant protein production using a cDNA screening system. (PubMed id 19466607)1, 9 Ku S.C....Chao S.H. (2009)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking. (PubMed id 22337587)1 Haines D.S....Deshaies R.J. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
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External Searches for UGGT1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing UGGT1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing UGGT1 gene
(According to HUGE)
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| -- |
Specialized Databases showing UGGT1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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|
| Name | Description |
| PharmGKB entry for UGGT1 | Pharmacogenomics, SNPs, Pathways | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/ |
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About This Section
| Patent Information for UGGT1 gene:
Search GeneIP for patents involving UGGT1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for UGGT1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for UGGT1 | | OriGene shRNA RFP for UGGT1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UGGT1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UGGT1 | | | OriGene Protein Over-expression Lysate for UGGT1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UGGT1 | | OriGene 3'-UTR Clone for UGGT1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UGGT1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UGGT1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UGGT1 | | OriGene Custom Protein Services for UGGT1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UGGT1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UGGT1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UGGT1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UGGT1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UGGT1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UGGT1 |
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| | | | Search Tocris compounds for UGGT1 |
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 | | | UGGT1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UGGT1 |
|  |  |  | | | | Search ThermoFisher Antibodies for UGGT1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UGGT1 |
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Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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