Aliases for UGCG Gene
External Ids for UGCG Gene
Previous GeneCards Identifiers for UGCG Gene
This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]
GeneCards Summary for UGCG Gene
UGCG (UDP-Glucose Ceramide Glucosyltransferase) is a Protein Coding gene. Diseases associated with UGCG include Gaucher's Disease and Gaucher Disease, Type I. Among its related pathways are Sphingolipid metabolism and IL2 signaling events mediated by PI3K. GO annotations related to this gene include ceramide glucosyltransferase activity.
UniProtKB/Swiss-Prot for UGCG Gene
Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".