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UFM1 Gene

protein-coding   GIFtS: 54
GCID: GC13P038923

Ubiquitin-Fold Modifier 1

(Previous name: chromosome 13 open reading frame 20)
(Previous symbol: C13orf20)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ubiquitin-Fold Modifier 11 2
C13orf201 2 3
Chromosome 13 Open Reading Frame 201
BM-0022

External Ids:    HGNC: 205971   Entrez Gene: 515692   Ensembl: ENSG000001206867   OMIM: 6105535   UniProtKB: P619603   

Export aliases for UFM1 gene to outside databases

Previous GC identifers: GC13P037822 GC13P019722


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for UFM1 Gene:
UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1;
MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M;
MIM 603173) (Komatsu et al., 2004 (PubMed 15071506)).(supplied by OMIM, Dec 2008)

GeneCards Summary for UFM1 Gene:
UFM1 (ubiquitin-fold modifier 1) is a protein-coding gene. Diseases associated with UFM1 include malaria.

UniProtKB/Swiss-Prot: UFM1_HUMAN, P61960
Function: Ubiquitin-like modifier protein which binds to a number of target proteins, such as DDRGK1

Gene Wiki entry for UFM1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NC_018924.2  NT_024524.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the UFM1 gene promoter:
         LHX3b/Lhx3b   ATF-2   HNF-1A   MEF-2A   PPAR-gamma1   HNF-1   LHX3a/Lhx3a   c-Jun   PPAR-gamma2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUFM1 promoter sequence
   Search Chromatin IP Primers for UFM1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UFM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q13.3   Ensembl cytogenetic band:  13q13.3   HGNC cytogenetic band: 13q13.3

UFM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UFM1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P038923:  view genomic region     (about GC identifiers)

Start:
38,923,942 bp from pter      End:
38,937,143 bp from pter
Size:
13,202 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: UFM1_HUMAN, P61960 (See protein sequence)
Recommended Name: Ubiquitin-fold modifier 1 precursor  
Size: 85 amino acids; 9118 Da
1 PDB 3D structure from and Proteopedia for UFM1:
1WXS (3D)    
Secondary accessions: Q14346 Q5VXS0 Q6IAG6 Q9CPX2 Q9NZF2
Alternative splicing: 2 isoforms:  P61960-1   P61960-2   

Explore the universe of human proteins at neXtProt for UFM1: NX_P61960

Explore proteomics data for UFM1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys19
  • Modification sites at PhosphoSitePlus

  • See UFM1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001273632.1  NP_001273633.1  NP_001273634.1  NP_001273635.1  NP_057701.1  

    ENSEMBL proteins: 
     ENSP00000368970   ENSP00000239878   ENSP00000402378   ENSP00000368962  

    UFM1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for UFM1

    UFM1 Antibody Products:

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    Cloud-Clone Corp. CLIAs for UFM1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005375 UFM1

    Graphical View of Domain Structure for InterPro Entry P61960

    ProtoNet protein and cluster: P61960

    1 Blocks protein domain: IPB005375 Protein of unknown function UPF0185

    UniProtKB/Swiss-Prot: UFM1_HUMAN, P61960
    Similarity: Belongs to the UFM1 family


    UFM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UFM1_HUMAN, P61960
    Function: Ubiquitin-like modifier protein which binds to a number of target proteins, such as DDRGK1

    Phenotypes:
         1 GenomeRNAi human phenotype for UFM1:

     Increased cell death in HCC-19 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UFM1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UFM1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UFM1

    miRNA
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    miRTarBase miRNAs that target UFM1:
    hsa-mir-30a-5p (MIRT028596)

    Block miRNA regulation of human, mouse, rat UFM1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UFM1 (see all 15):
    hsa-miR-98 hsa-miR-1294 hsa-let-7d hsa-miR-545 hsa-let-7c hsa-miR-488 hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidUFM1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat UFM1

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UFM1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UFM1_HUMAN, P61960: Nucleus. Cytoplasm. Note=Predominantly nuclear. Also expressed diffusely in the cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    endoplasmic reticulum2
    cytosol1
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15071506
    GO:0005737cytoplasm IDA15071506

    UFM1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UFM1
    Interactions:

        Search GeneGlobe Interaction Network for UFM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for UFM1 (P619601, 2, 3 ENSP000002398784) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGDIBP525662, 3, ENSP000002289454MINT-8276883 I2D: score=2 STRING: ENSP00000228945
    DIABLOQ9NR282, 3, ENSP000002671694MINT-8254122 I2D: score=2 STRING: ENSP00000267169
    ARHGDIAP525652, 3MINT-8276872 I2D: score=2 
    GSK3BP498412, 3MINT-8257801 I2D: score=2 
    RPS6KA6Q9UK322, 3MINT-8269956 I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034976response to endoplasmic reticulum stress IDA--
    GO:0071569protein ufmylation IDA15071506

    UFM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UFM1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for UFM1 gene (5 alternative transcripts): 
    NM_001286703.1  NM_001286704.1  NM_001286705.1  NM_001286706.1  NM_016617.3  

    Unigene Cluster for UFM1:

    Ubiquitin-fold modifier 1
    Hs.643655  [show with all ESTs]
    Unigene Representative Sequence: NM_016617
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000494372 ENST00000379649(uc010aca.2) ENST00000239878(uc001uwu.3)
    ENST00000464423 ENST00000437952(uc010abz.2) ENST00000379641
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat UFM1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UFM1 (see all 15):
    hsa-miR-98 hsa-miR-1294 hsa-let-7d hsa-miR-545 hsa-let-7c hsa-miR-488 hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidUFM1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for UFM1
    Predesigned siRNA for gene silencing in human, mouse, rat UFM1
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UFM1 (NM_016617)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UFM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UFM1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for UFM1
    OriGene qSTAR qPCR primer pairs in human, mouse for UFM1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat UFM1
      QuantiTect SYBR Green Assays in human, mouse, rat UFM1
      QuantiFast Probe-based Assays in human, mouse, rat UFM1

    Additional mRNA sequence: 

    AB154404.1 AF208844.1 AF305827.2 AF369953.1 AK095490.1 AK307111.1 AK309914.1 BC005193.1 
    CR457189.1 Z70222.1 

    20 DOTS entries:

    DT.92442455  DT.100793892  DT.120782889  DT.91994466  DT.92442457  DT.100650864  DT.428877  DT.100793894 
    DT.100793891  DT.92442460  DT.92442462  DT.99953251  DT.120782865  DT.120782891  DT.92442456  DT.92442458 
    DT.92442459  DT.120782856  DT.92442465  DT.95152933 

    Selected AceView cDNA sequences (see all 327):

    AA677539 AL515797 CA395682 AA339642 CB070175 AI393910 AA766135 AL600755 
    BP338267 CA773783 F12644 BU069074 AA747909 BM926968 AI073905 AA452076 
    AI371710 AB154404 AA628783 AL554429 AA315780 CR457189 BP343753 CK429252 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for UFM1 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5
    SP1:                                -           -     -               
    SP2:                                            -     -               
    SP3:                                -           -     -     -         
    SP4:                                -           -     -               
    SP5:                                -                                 


    ECgene alternative splicing isoforms for UFM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UFM1 expression in normal human tissues (normalized intensities)      UFM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTTATATT
    UFM1 Expression
    About this image


    UFM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
     
     Adrenal Gland (Endocrine System)
    UFM1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UFM1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.643655
        Custom PCR Arrays for UFM1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UFM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for UFM1 gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ufm11 , 5 ubiquitin-fold modifier 11, 5 89.8(n)1
    100(a)1
      3 (25.43 cM)5
    678901  NM_026435.51  NP_080711.11 
     538552125 
    chicken
    (Gallus gallus)
    Aves UFM11 ubiquitin-fold modifier 1 84.71(n)
    95.29(a)
      418894  NM_001030827.1  NP_001025998.1 
    lizard
    (Anolis carolinensis)
    Reptilia UFM16
    ubiquitin-fold modifier 1
    95(a)
    1 ↔ 1
    GL343608.1(225972-229459)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX843073.12   -- 83.45(n)    BX843073.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AY394956.12   -- 82.47(n)    AY394956.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG341911 CG34191 69.88(n)
    87.95(a)
      5740715  NM_001103884.3  NP_001097354.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tag-2771 tag-277 69.11(n)
    90.24(a)
      176100  NM_066304.5  NP_498705.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G777101 AT1G77710 69.44(n)
    83.33(a)
      844107  NM_106420.4  NP_177894.1 
    rice
    (Oryza sativa)
    Liliopsida Os.55202 Oryza sativa (japonica cultivar-group) cDNA clone0 more 71.35(n)    AK059165.1 


    ENSEMBL Gene Tree for UFM1 (if available)
    TreeFam Gene Tree for UFM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UFM1 gene

    UFM1 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for UFM1
    PGOHUM00000237031 PGOHUM00000241016 PGOHUM00000249456 PGOHUM00000242061


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UFM1 (see all 355)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3682028301,2
    --19731011(+) TATAT-/ATTTTT 1 -- int10--------
    rs20195161,2
    C,F,O,A,H--38922011(+) TTAACT/GTTTCA 1 -- us2k113Minor allele frequency- G:0.13NS EA NA WA CSA 802
    rs20195201,2
    C,F,A,H--38922043(+) TTGCTG/ATAAAA 1 -- us2k1 tfbs313Minor allele frequency- A:0.20NS EA NA WA 788
    rs10327531,2
    F,H--38922069(-) TTGTGA/GAGGGA 1 -- us2k14Minor allele frequency- G:0.01NS EA 420
    rs1917925611,2
    --38922449(+) AACTAC/TAAATA 1 -- us2k10--------
    rs1380705991,2
    --38922463(+) GGATGC/TAAATT 1 -- us2k10--------
    rs1153354411,2
    C,F--38922744(+) AATGTT/CGGAGT 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1437358621,2
    --38922804(+) ATAGAA/CGATCA 1 -- us2k10--------
    rs10114841,2
    C,F,O,H--38922812(+) TCAGTT/AGGCTG 1 -- us2k116Minor allele frequency- A:0.14MN NS EA NA WA CSA 959
    rs172978151,2
    C,F--38922826(+) AATTAT/CTGTAA 1 -- us2k13Minor allele frequency- C:0.01NA 140

    HapMap Linkage Disequilibrium report for UFM1 (38923942 - 38937143 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for UFM1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv900005CNV Loss21882294
    nsv900006CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UFM1
    DNA2.0 Custom Variant and Variant Library Synthesis for UFM1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610553    OMIM disorders: --

    1 disease for UFM1:    About MalaCards
    malaria


    UFM1 for disorders           About GeneDecksing


    Export disorders for UFM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UFM1 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with UFM1)
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    1. A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier. (PubMed id 15071506)1, 2, 3 Komatsu M.... Tanaka K. (EMBO J. 2004)
    2. Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1. (PubMed id 16527251)1, 2, 9 Sasakawa H.... Kato K. (Biochem. Biophys. Res. Commun. 2006)
    3. A novel type of E3 ligase for the Ufm1 conjugation system. (PubMed id 20018847)1, 2 Tatsumi K.... Komatsu M. (J. Biol. Chem. 2010)
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1, 2 Kimura K.... Sugano S. (Genome Res. 2006)
    5. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    10. Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking. (PubMed id 23152784)1 Zhang Y....Li H. (PLoS ONE 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51569 HGNC: 20597 AceView: Ufm1 Ensembl:ENSG00000120686 euGenes: HUgn51569
    ECgene: UFM1 H-InvDB: UFM1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UFM1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UFM1 gene:
    Search GeneIP for patents involving UFM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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