Aliases for UCN3 Gene
External Ids for UCN3 Gene
Previous GeneCards Identifiers for UCN3 Gene
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
GeneCards Summary for UCN3 Gene
UCN3 (Urocortin 3) is a Protein Coding gene. Diseases associated with UCN3 include pheochromocytoma. Among its related pathways are G-Beta Gamma Signaling and Glucocorticoid Pathway (HPA Axis), Pharmacodynamics. GO annotations related to this gene include hormone activity and corticotropin-releasing hormone receptor 2 binding.
UniProtKB/Swiss-Prot for UCN3 Gene
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress