Aliases for UCN2 Gene
External Ids for UCN2 Gene
Previous GeneCards Identifiers for UCN2 Gene
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
GeneCards Summary for UCN2 Gene
UCN2 (Urocortin 2) is a Protein Coding gene. Diseases associated with UCN2 include alcohol dependence. Among its related pathways are Glucocorticoid Pathway (HPA Axis), Pharmacodynamics. GO annotations related to this gene include receptor binding and hormone binding.
UniProtKB/Swiss-Prot for UCN2 Gene
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress