Aliases for UCKL1 Gene
External Ids for UCKL1 Gene
Previous HGNC Symbols for UCKL1 Gene
Previous GeneCards Identifiers for UCKL1 Gene
The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
GeneCards Summary for UCKL1 Gene
UCKL1 (Uridine-Cytidine Kinase 1 Like 1) is a Protein Coding gene. Among its related pathways are Purine metabolism (KEGG) and Porphyrin and chlorophyll metabolism. GO annotations related to this gene include kinase activity and uridine kinase activity. An important paralog of this gene is MIR3658.
UniProtKB/Swiss-Prot for UCKL1 Gene
May contribute to UTP accumulation needed for blast transformation and proliferation.