Aliases for UCHL5 Gene
External Ids for UCHL5 Gene
Previous GeneCards Identifiers for UCHL5 Gene
GeneCards Summary for UCHL5 Gene
UCHL5 (Ubiquitin C-Terminal Hydrolase L5) is a Protein Coding gene. Among its related pathways are TGF-beta receptor signaling activates SMADs and Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer. GO annotations related to this gene include poly(A) RNA binding and endopeptidase inhibitor activity. An important paralog of this gene is BAP1.
UniProtKB/Swiss-Prot for UCHL5 Gene
Protease that specifically cleaves Lys-48-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.