Aliases for UCHL5 Gene
External Ids for UCHL5 Gene
GeneCards Summary for UCHL5 Gene
UCHL5 (Ubiquitin Carboxyl-Terminal Hydrolase L5) is a Protein Coding gene. Diseases associated with UCHL5 include cannabis dependence. Among its related pathways are Signaling by GPCR and Disease. GO annotations related to this gene include ubiquitin thiolesterase activity and endopeptidase inhibitor activity. An important paralog of this gene is BAP1.
UniProtKB/Swiss-Prot for UCHL5 Gene
Protease that specifically cleaves Lys-48-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.