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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

UBXN4 Gene

protein-coding GIFtS: 50
GCID: GC02P136500

UBX domain protein 4

(Previous names: UBX domain-containing 2, UBX domain containing 2 )
(Previous symbols: UBXDC1, UBXD2)

Explore 2 diseases affiliated with
UBXN4 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
UBX Domain Protein 4¹ ²		UBX Domain-Containing 2¹
UBXD2¹ ² ³		Erasin³
UBXDC1¹ ² ³		UBX Domain-Containing 1²
UBX Domain Containing 2¹ ²		UBX Domain-Containing Protein 4²
KIAA0242¹ ³		Erasin³
UBX Domain-Containing Protein 2² ³

External Ids:	HGNC: 14860¹	Entrez Gene: 23190²	Ensembl: ENSG00000144224⁷	OMIM: 611216⁵	UniProtKB: Q92575³

Export aliases for UBXN4 gene to outside databases

Previous GC identifers: GC02P136216 GC02P128493

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UBXN4:

UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM

601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 (PubMed 16968747)).(supplied by

OMIM, Mar 2008)

UniProtKB/Swiss-Prot: UBXN4_HUMAN, Q92575

Function: Involved in endoplasmic reticulum-associated protein degradation (ERAD)

Gene Wiki entry for UBXN4 (UBXD2)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022135.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the UBXN4 gene promoter:
TBP AREB6 USF1 AML1a USF-1 MyoD ATF6
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UBXN4 promoter sequence

Search SABiosciences Chromatin IP Primers for UBXN4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBXN4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q21.3 Ensembl cytogenetic band: 2q21.3 HGNC cytogenetic band: 2q21.3-q22.1

UBXN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBXN4 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P136500: view genomic region (about GC identifiers)

Start:	136,499,189 bp from pter	End:	136,542,633 bp from pter
Size:	43,445 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UBXN4_HUMAN, Q92575 (See protein sequence)

Recommended Name: UBX domain-containing protein 4

Size: 508 amino acids; 56778 Da

Subunit: Directly interacts with VCP

Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope. Note=Both the N-

and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER

Sequence caution: Sequence=BAA13437.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

1 PDB 3D structure from and Proteopedia for UBXN4:

2KXJ (3D)

Secondary accessions: A8K9W4 Q4ZG56 Q8IYM5

Explore the universe of human proteins at neXtProt for UBXN4: NX_Q92575

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q92575

UBXN4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055422.1

ENSEMBL proteins:

ENSP00000272638 ENSP00000401748 ENSP00000410516 ENSP00000391586

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	Uscn Proteins for UBXN4

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005635	nuclear envelope	IEA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0005783	endoplasmic reticulum	IDA	--

UBXN4 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for UBXN4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UBXN4 for domains About GeneDecksing

2 InterPro domains/families:

IPR001012 UBX

IPR012336 Thioredoxin-like_fold

Graphical View of Domain Structure for InterPro Entry Q92575

ProtoNet protein and cluster: Q92575

UniProtKB/Swiss-Prot: UBXN4_HUMAN, Q92575

Domain: The UBX domain is required for interaction with VCP

Domain: The intramembrane domain also contains the signal for ER targeting

Similarity: Contains 1 UBX domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: UBXN4_HUMAN, Q92575

Function: Involved in endoplasmic reticulum-associated protein degradation (ERAD)

Induction: By ER stress-inducing agents such as tunicamycin, thapsigargin, DTT and the calcium ionophore A23187 (at

protein level)

miRNA Products:		OriGene 3'-UTR Clone: UBXN4 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UBXN4
		8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate UBXN4 (see all 49):
		hsa-let-7d hsa-miR-25 hsa-miR-374a hsa-miR-766 hsa-let-7g hsa-miR-183* hsa-let-7a hsa-miR-4274

		SwitchGear 3'UTR luciferase reporter plasmid: UBXN4 3' UTR sequence

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBXN4

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	18775313

UBXN4 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for UBXN4:

High actin ratio cells

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for UBXN4

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/10 Interacting proteins for UBXN4 (Q92575^{1, 2, 3} ENSP00000272638⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
VCP	P55072¹^,³, ENSP00000351777⁴	EBI-723441,EBI-1046421 I2D: score=2 STRING: ENSP00000351777
TOM1L1	O75674²^,³	MINT-64319 I2D: score=5
ZNF24	P17028³	I2D: score=1
UBQLN1	ENSP00000365576⁴	STRING: ENSP00000365576
SEL1L	ENSP00000337053⁴	STRING: ENSP00000337053

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006986	response to unfolded protein	IEA	--

UBXN4 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UBXN4

1 HMDB Compound for UBXN4 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

Search CenterWatch for drugs/clinical trials and news about UBXN4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for UBXN4 gene:

NM_014607.3

Unigene Cluster for UBXN4:

UBX domain protein 4

Hs.591242 [show with all ESTs]

Unigene Representative Sequence: NM_014607

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000272638(uc002tur.3 uc002tus.3) ENST00000415164 ENST00000426921

ENST00000416538 ENST00000467065 ENST00000470687 ENST00000490163(uc002tut.3)

ENST00000471246

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UBXN4
		8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate UBXN4 (see all 49):
		hsa-let-7d hsa-miR-25 hsa-miR-374a hsa-miR-766 hsa-let-7g hsa-miR-183* hsa-let-7a hsa-miR-4274

		SwitchGear 3'UTR luciferase reporter plasmid: UBXN4 3' UTR sequence

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Additional cDNA sequence:

AK026971.1 AK056055.1 AK095402.1 AK292829.1 AK304096.1 BC035594.2 BX647662.1 D87684.1

EF199840.1

18 DOTS entries:

DT.95154663 DT.95131553 DT.119331 DT.91756873 DT.101983743 DT.120981999 DT.95072025 DT.95154664

DT.120981941 DT.100804686 DT.40116485 DT.95154662 DT.100804687 DT.102830973 DT.120981916 DT.91756888

DT.120981929 DT.120981975

24/461 AceView cDNA sequences (see all 461):

AA602575 AA622115 BU952556 AW295423 BU951120 BM310341 CA395992 CR600206

AW070493 C02511 BE222898 N29889 BX503741 H77511 CA941756 F34597

AW519061 BU428757 BG105846 F32043 AA298907 AA298495 AA298976 AA298838

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

UBXN4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCCCAGGA

About this image

UBXN4 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Head Mesenchyme

Branchial Arch 1

Paraxial Mesoderm Cells

Bone, Skeletal Muscle

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See UBXN4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBXN4

SOURCE GeneReport for Unigene cluster: Hs.591242

UniProtKB/Swiss-Prot: UBXN4_HUMAN, Q92575

Tissue specificity: Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney

and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level)

SABiosciences Expression via Pathway-Focused PCR Arrays including UBXN4:

Unfolded Protein Response in human mouse rat

Molecular Toxicology PathwayFinder 384HT in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBXN4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for UBXN4 gene from 9/28 species (see all 28) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ubxn4^{1 , 5}	UBX domain protein 4^{1, 5}	86.43(n)¹ 89.72(a)¹		1 (55.80 cM)⁵ 67812¹ NM_026390.2¹ NP_080666.2¹ 128244181⁵
chicken (Gallus gallus)	Aves	UBXN4¹	UBX domain protein 4	71.73(n) 71.79(a)		424293 XM_422138.3 XP_422138.1
lizard (Anolis carolinensis)	Reptilia	UBXN4⁶	--	69(a)	1 ↔ 1	1(96693704-96714250)
African clawed frog (Xenopus laevis)	Amphibia	Xl.15108²	Xenopus laevis transcribed sequence with weak similarity more	75.25(n)		BX844490.1
zebrafish (Danio rerio)	Actinopterygii	Dr.16757²	Danio rerio cDNA clone MGC73362 IMAGE4144799, complete more	74.33(n)		BC064707.1
fruit fly (Drosophila melanogaster)	Insecta	CG8042¹	CG8042	45.4(n) 38.88(a)		38886 NM_139908.2 NP_648165.1
worm (Caenorhabditis elegans)	Secernentea	ubxn-4¹	Protein UBXN-4	42.77(n) 28.76(a)		176187 NM_066455.3 NP_498856.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G43210¹	UBX domain-containing protein	41.09(n) 24.9(a)		818922 NM_180059.1 NP_850390.1
rice (Oryza sativa)	Liliopsida	Os11g0293900¹	hypothetical protein	40.26(n) 26.2(a)		4350306 NM_001074245.1 NP_001067713.1

ENSEMBL Gene Tree for UBXN4 (if available)
TreeFam Gene Tree for UBXN4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for UBXN4 gene

UBXN1²

18/26 SIMAP similar genes for UBXN4 using alignment to 4 protein entries: UBXN4_HUMAN (see all proteins) (see all similar genes):

CLTA AAMDC LSM12 ADCK1 COQ5 NDC80

TBCB ZNF559 SEC14L3 RPS13 TUBA1C FLJ00047

TMX3 PFKFB3 MRPL45 NCKAP1L C4BPB GALK2

UBXN4 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for UBXN4
PGOHUM00000241271

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs12476116^1,2	C,H,	--	136497199(+)	`tattcA/Gattgc`	1	--	us2k¹		4		WA NA EA	360
rs181970746^1,2		--	136497276(+)	`TCTTGC/TTCTTT`	1	--	us2k¹		0	--	--	--	--
rs186396279^1,2		--	136497327(+)	`CAACCA/TCCACC`	1	--	us2k¹		0	--	--	--	--
rs62168848^1,2		--	136497347(+)	`CAAGCG/AATTCT`	1	--	us2k¹		1		NA	2
rs190901254^1,2		--	136497791(+)	`TCCCCA/GACACG`	1	--	us2k¹		0	--	--	--	--
rs151300517^1,2		--	136497841(+)	`ATGTTC/TGGTCC`	1	--	us2k¹		0	--	--	--	--
rs180890098^1,2		--	136498140(+)	`TCAAAC/TTTCCA`	1	--	us2k¹		0	--	--	--	--
rs140588457^1,2		--	136498156(+)	`CCATTA/CAAGTT`	1	--	us2k¹		0	--	--	--	--
rs77101274^1,2	F,	--	136498211(+)	`ATAGAA/CGCAAC`	1	--	us2k¹		1		WA	118
rs150486299^1,2		--	136498218(+)	`CAACTA/GTCCCT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for UBXN4 (136499189 - 136542633 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for UBXN4
2 CNVs: 58920 47933

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBXN4

DNA2.0 Custom Variant and Variant Library Synthesis for UBXN4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

UBXN4 for disorders           About GeneDecksing

OMIM gene information: 611216    OMIM disorders: --

2 diseases for UBXN4:    About MalaCards

alzheimer's disease malaria

Export disorders for UBXN4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for UBXN4 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with UBXN4)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation. (PubMed id 16968747)^{1, 2, 3} Liang J....Monteiro M.J. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)^{1, 2} Nagase T....Nomura N. (1996)
A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal trans plantation in developed countries. (PubMed id 21979947)¹ Li X....Rabinowitz Y.S. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD. (PubMed id 19822669)¹ Lim P.J....Monteiro M.J. (2009)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23190	HGNC: 14860	AceView: UBXD2	Ensembl:ENSG00000144224	euGenes: HUgn23190
ECgene: UBXN4	H-InvDB: UBXN4

(According to HUGE)
About This Section

HUGE: KIAA0242

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for UBXN4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for UBXN4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for UBXN4 gene:
Search GeneIP for patents involving UBXN4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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UBXN4 Gene

UBX domain protein 4

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UBXN4 Gene

UBX domain protein 4

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