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UBXN2A Gene

protein-coding   GIFtS: 49
GCID: GC02P024150

UBX Domain Protein 2A

(Previous name: UBX domain containing 4)
(Previous symbol: UBXD4)
  Search for UBXN2A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
UBX Domain Protein 2A1 2
UBXD41 2 3
UBX Domain Containing 41 2
UBX Domain-Containing Protein 42 3
UBX Domain-Containing Protein 2A2

External Ids:    HGNC: 272651   Entrez Gene: 1653242   Ensembl: ENSG000001739607   UniProtKB: P685433   
ORGUL members:         

Export aliases for UBXN2A gene to outside databases

Previous GC identifers: GC02P024003 GC02P023902


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UBXN2A Gene:
UBXN2A (UBX domain protein 2A) is a protein-coding gene. GO annotations related to this gene include acetylcholine receptor binding. An important paralog of this gene is UBXN2B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UBXN2A gene promoter:
         TBP   AhR   HOXA9   HOXA9B   AML1a   MIF-1   Meis-1b   AREB6   TFIID   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUBXN2A promoter sequence
   Search Chromatin IP Primers for UBXN2A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBXN2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p24.1

UBXN2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBXN2A gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P024150:  view genomic region     (about GC identifiers)

Start:
24,150,155 bp from pter      End:
24,227,779 bp from pter
Size:
77,625 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: UBX2A_HUMAN, P68543 (See protein sequence)
Recommended Name: UBX domain-containing protein 2A  
Size: 259 amino acids; 29278 Da
Secondary accessions: A8K577 Q569G8

Explore the universe of human proteins at neXtProt for UBXN2A: NX_P68543

Explore proteomics data for UBXN2A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys69, Lys205
  • Modification sites at PhosphoSitePlus

  • See UBXN2A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_859064.2  
    ENSEMBL proteins: 
     ENSP00000385525   ENSP00000312107   ENSP00000440533  

    UBXN2A Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UBXN2A

     
    Search eBioscience for Proteins for UBXN2A 

    UBXN2A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for UBXN2A
    Cloud-Clone Corp. CLIAs for UBXN2A
    Search eBioscience for ELISAs for UBXN2A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    UBXN: UBX domain containing

    2 InterPro protein domains:
     IPR012989 SEP_domain
     IPR001012 UBX

    Graphical View of Domain Structure for InterPro Entry P68543

    ProtoNet protein and cluster: P68543

    1 Blocks protein domain: IPB001012 UBX domain

    UniProtKB/Swiss-Prot: UBX2A_HUMAN, P68543
    Similarity: Contains 1 SEP domain
    Similarity: Contains 1 UBX domain


    Find genes that share domains with UBXN2A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0033130acetylcholine receptor binding IEA--
         
    Find genes that share ontologies with UBXN2A           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for UBXN2A:
     Synthetic lethal with Ras  Upregulation of NF-kappaB path 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UBXN2A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for UBXN2A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UBXN2A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UBXN2A

    miRNA
    Products:
        
    miRTarBase miRNAs that target UBXN2A:
    hsa-mir-590-3p (MIRT016205), hsa-mir-93-5p (MIRT028042), hsa-mir-130b-3p (MIRT020181)

    Block miRNA regulation of human, mouse, rat UBXN2A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UBXN2A (see all 21):
    hsa-miR-106a hsa-miR-605 hsa-miR-519a hsa-miR-93 hsa-miR-548x hsa-miR-3613-3p hsa-miR-3143 hsa-miR-17
    SwitchGear 3'UTR luciferase reporter plasmidUBXN2A 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat UBXN2A

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: UBXN2A (NM_181713)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UBXN2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBXN2A

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for UBXN2A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBXN2A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    endoplasmic reticulum2
    nucleus2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IEA--
    GO:0005801cis-Golgi network IEA--
    GO:0005829cytosol IEA--

    Find genes that share ontologies with UBXN2A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including UBXN2A: 
              Cardiotoxicity in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for UBXN2A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for UBXN2A (P685432, 3 ENSP000003121074) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PHAXQ9H8142, 3, ENSP000002975404MINT-8276658 I2D: score=2 STRING: ENSP00000297540
    VCPP550722, 3, ENSP000003517774MINT-8276669 I2D: score=2 STRING: ENSP00000351777
    DBIP071082, 3, ENSP000003111174MINT-8276642 I2D: score=2 STRING: ENSP00000311117
    VCPIP1Q96JH73, ENSP000003090314I2D: score=2 STRING: ENSP00000309031
    PLAAENSP000003804604STRING: ENSP00000380460
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010468regulation of gene expression IEA--
    GO:0031396regulation of protein ubiquitination IEA--
    GO:0042176regulation of protein catabolic process IEA--

    Find genes that share ontologies with UBXN2A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UBXN2A (UBX2A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for UBXN2A gene: 
    NM_181713.3  

    Unigene Cluster for UBXN2A:

    UBX domain protein 2A
    Hs.591576  [show with all ESTs]
    Unigene Representative Sequence: BC037901
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000446425(uc002rem.3 uc010exy.3) ENST00000404924 ENST00000309033(uc002ren.3 uc010ykj.2)
    ENST00000479859 ENST00000535786
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat UBXN2A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UBXN2A (see all 21):
    hsa-miR-106a hsa-miR-605 hsa-miR-519a hsa-miR-93 hsa-miR-548x hsa-miR-3613-3p hsa-miR-3143 hsa-miR-17
    SwitchGear 3'UTR luciferase reporter plasmidUBXN2A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for UBXN2A
    Predesigned siRNA for gene silencing in human, mouse, rat UBXN2A
    Clone
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    OriGene clones in human, mouse for UBXN2A (see all 7)
    OriGene ORF clones in mouse, rat for UBXN2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: UBXN2A (NM_181713)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for UBXN2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBXN2A
    Primer
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    OriGene qPCR primer pairs and template standards for UBXN2A
    OriGene qSTAR qPCR primer pairs in human, mouse for UBXN2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UBXN2A
      QuantiTect SYBR Green Assays in human, mouse, rat UBXN2A
      QuantiFast Probe-based Assays in human, mouse, rat UBXN2A

    Additional mRNA sequence: 

    AK291192.1 AL832079.1 BC016364.1 BC037901.2 BC092484.1 BC093681.1 BC111997.1 BC143298.1 

    6 DOTS entries:

    DT.423492  DT.100740275  DT.91713266  DT.101973668  DT.101960707  DT.40246630 

    Selected AceView cDNA sequences (see all 83):

    AL694062 W19108 AW207623 BM451942 BQ787308 N94958 AI918322 T54751 
    W19529 N70658 BE882535 BU070305 W19851 CB109184 AI149289 BQ021843 
    BI862062 R33572 AK054572 CF994708 AI743403 BQ441702 BF983757 AA568122 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for UBXN2A    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8
    SP1:                    -                       -                     
    SP2:                                            -                     
    SP3:              -     -                       -                     
    SP4:                                                                  


    ECgene alternative splicing isoforms for UBXN2A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UBXN2A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAACCAAAA
    UBXN2A Expression
    About this image

    UBXN2A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UBXN2A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591576
        Pathway & Disease-focused RT2 Profiler PCR Array including UBXN2A: 
              Cardiotoxicity in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for UBXN2A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBXN2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for UBXN2A gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ubxn2a1 , 5 UBX domain protein 2A1, 5 87.76(n)1
    85.55(a)1
      12 (2.13 cM)5
    2173791  NM_145441.31  NP_663416.11 
     48790325 
    chicken
    (Gallus gallus)
    Aves UBXN2A1 UBX domain protein 2A 68.12(n)
    63.64(a)
      421973  NM_001031094.1  NP_001026265.1 
    lizard
    (Anolis carolinensis)
    Reptilia UBXN2A6
    UBX domain protein 2A
    56(a)
    1 ↔ 1
    1(140392915-140410501)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480547092   -- 73.55(n)    48054709 
    zebrafish
    (Danio rerio)
    Actinopterygii ubxn2a1 UBX domain protein 2A 53(n)
    44.77(a)
      100537478  XM_003200752.2  XP_003200800.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta p476
    CG423836
    --
    18(a)
    17(a)
    many ↔ many
    many ↔ many
    2R(3352523-3354236)
    2R(20311449-20312625)
    worm
    (Caenorhabditis elegans)
    Secernentea ubxn-26
    Protein UBXN-2, isoform a
    20(a)
    1 → many
    IV(2720323-2725858) WBGene00022381
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SHP16
    UBX (ubiquitin regulatory X) domain-containing pro...
    16(a)
    1 → many
    II(111437-112708) YBL058W


    ENSEMBL Gene Tree for UBXN2A (if available)
    TreeFam Gene Tree for UBXN2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UBXN2A gene
    UBXN2B2  NSFL1C2  
    2 SIMAP similar genes for UBXN2A using alignment to 2 protein entries:     UBX2A_HUMAN (see all proteins):
    NSFL1C    UBXN2B

    Find genes that share paralogs with UBXN2A           About GenesLikeMe


    4 Pseudogenes.org Pseudogenes for UBXN2A
    PGOHUM00000234142 PGOHUM00000245562 PGOHUM00000235157 PGOHUM00000235557


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UBXN2A (see all 1204)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs673498031,2
    C--24084320(+) GGGCT-/T/TT  
            
    TTTTT
    1 -- int10--------
    rs2000684411,2
    C--24161418(+) GCCCC-/CCCCT 
            
    CCCTT
    1 -- us2k10--------
    rs2012319431,2
    --24161419(+) CCCCC-/CCCT  
            
    CCCTT
    1 -- us2k10--------
    rs1889066241,2
    --24161521(+) AGTTGA/GAGGAC 1 -- us2k10--------
    rs1922442621,2
    --24161662(+) GAAATA/CAATTT 1 -- us2k10--------
    rs9258231,2
    C,H--24161788(+) CCTAAC/TGGGAT 1 -- us2k114Minor allele frequency- T:0.00MN NA WA CSA EA 559
    rs1499298161,2
    --24161829(+) CACGGG/TCTCAT 1 -- us2k10--------
    rs1827689391,2
    --24161833(+) GTCTCA/CTGAGC 1 -- us2k10--------
    rs1450265021,2
    --24161960(+) GCACTA/GAAGAC 1 -- us2k10--------
    rs75729491,2
    C,F,H--24162018(+) gattaC/Ttgcaa 1 -- us2k121Minor allele frequency- T:0.44NS EA NA WA 2348

    HapMap Linkage Disequilibrium report for UBXN2A (24150155 - 24227779 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for UBXN2A: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UBXN2A
    DNA2.0 Custom Variant and Variant Library Synthesis for UBXN2A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for UBXN2A gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with UBXN2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. The ubiquitin-like (UBX)-domain-containing protein Ubx2/Ubxd8 regulates lipid droplet homeostasis. (PubMed id 22454508)1 Wang C.W. and Lee S.C. (J. Cell. Sci. 2012)
    4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients. (PubMed id 21326311)1 Bhatnagar P....Keefer J.R. (J. Hum. Genet. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    10. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. (PubMed id 19197348)1 Lowe J.K....Friedman J.M. (PLoS Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 165324 HGNC: 27265 AceView: UBXD4 Ensembl:ENSG00000173960 euGenes: HUgn165324
    ECgene: UBXN2A H-InvDB: UBXN2A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UBXN2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UBXN2A gene:
    Search GeneIP for patents involving UBXN2A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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