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UBXN1 Gene

protein-coding   GIFtS: 52
GCID: GC11M062489

UBX Domain Protein 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
UBX Domain Protein 11 2     2B282
SAPK Substrate Protein 11 2 3     UBXD102
SAKS12 3     UBX Domain-Containing Protein 12
UBA/UBX 33.3 KDa Protein2 3     

External Ids:    HGNC: 184021   Entrez Gene: 510352   Ensembl: ENSG000001621917   UniProtKB: Q043233   

Export aliases for UBXN1 gene to outside databases

Previous GC identifers: GC11M062201 GC11M062444 GC11M058772 GC11M062447 GC11M062462 GC11M062471 GC11M062477


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UBXN1 Gene:
UBXN1 (UBX domain protein 1) is a protein-coding gene. GO annotations related to this gene include ATPase binding and ubiquitin protein ligase binding. An important paralog of this gene is UBXN4.

UniProtKB/Swiss-Prot: UBXN1_HUMAN, Q04323
Function: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity.
Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to
inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required
to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum
that are retrotranslocated in the cytosol




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_167190.2  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UBXN1 gene promoter:
         E2F-3a   E2F-4   NF-1   NF-1/L   E2F-5   E2F-2   RORalpha1   E2F   E2F-1   ZIC2/Zic2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUBXN1 promoter sequence
   Search Chromatin IP Primers for UBXN1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBXN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.3   Ensembl cytogenetic band:  11q12.3   HGNC cytogenetic band: 11q23

UBXN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBXN1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M062489:  view genomic region     (about GC identifiers)

Start:
62,443,970 bp from pter      End:
62,446,567 bp from pter
Size:
2,598 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: UBXN1_HUMAN, Q04323 (See protein sequence)
Recommended Name: UBX domain-containing protein 1  
Size: 297 amino acids; 33325 Da
Subunit: Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed
of NGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with HOMER2 (By similarity). Interacts directly with VCP.
Interacts with BRCA1 and BARD1; interaction takes place when BRCA1 is not autoubiquitinated but is strongly
enhanced in the presence of autoubiquitinated BRCA1
Secondary accessions: Q9BV93 Q9BVV5
Alternative splicing: 2 isoforms:  Q04323-1   Q04323-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UBXN1: NX_Q04323

Explore proteomics data for UBXN1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys83, Lys105, Lys154, Lys178, Lys208
  • Modification sites at PhosphoSitePlus

  • See UBXN1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273006.1  NP_001273007.1  NP_056937.2  

    ENSEMBL proteins: 
     ENSP00000294119   ENSP00000303991   ENSP00000432189   ENSP00000435964   ENSP00000435625  

    UBXN1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for UBXN1

     
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    antibodies-online proteins for UBXN1 (6 products) 

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    UBXN: UBX domain containing

    4 InterPro protein domains:
     IPR009060 UBA-like
     IPR000449 UBA/Ts_N
     IPR015940 UBA/transl_elong_EF1B_N_euk
     IPR001012 UBX

    Graphical View of Domain Structure for InterPro Entry Q04323

    ProtoNet protein and cluster: Q04323

    1 Blocks protein domain: IPB001012 UBX domain

    UniProtKB/Swiss-Prot: UBXN1_HUMAN, Q04323
    Domain: The UBA domain specifically recognizes and binds 'Lys-6'-linked polyubiquitin chains
    Similarity: Contains 1 UBA domain
    Similarity: Contains 1 UBX domain


    Find genes that share domains with UBXN1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UBXN1_HUMAN, Q04323
    Function: Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity.
    Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to
    inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required
    to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum
    that are retrotranslocated in the cytosol

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0031593polyubiquitin binding IDA15362974
    GO:0031625ubiquitin protein ligase binding IDA18775313
    GO:0043130ubiquitin binding IDA18775313
    GO:0051117ATPase binding IPI15362974
         
    Find genes that share ontologies with UBXN1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for UBXN1:
     Decreased nuclei size in G2M  Low eccentricity cells 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for UBXN1

    miRNA
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    miRTarBase miRNAs that target UBXN1:
    hsa-mir-615-3p (MIRT040124), hsa-mir-30c-5p (MIRT047839), hsa-mir-155-5p (MIRT020578), hsa-mir-27b-3p (MIRT046169), hsa-mir-373-3p (MIRT003817), hsa-mir-30e-3p (MIRT044114)

    Block miRNA regulation of human, mouse, rat UBXN1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UBXN1 (see all 15):
    hsa-miR-520f hsa-miR-588 hsa-miR-148b hsa-miR-922 hsa-miR-548s hsa-miR-374a* hsa-miR-223 hsa-miR-152
    SwitchGear 3'UTR luciferase reporter plasmidUBXN1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat UBXN1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UBXN1_HUMAN, Q04323: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    cytosol2
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000502colocalizes with proteasome complex IDA15362974
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA10942595
    GO:0030425dendrite IEA--
    GO:0034098Cdc48p-Npl4p-Ufd1p AAA ATPase complex IDA18775313

    Find genes that share ontologies with UBXN1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UBXN1
    Interactions:

        GeneGlobe Interaction Network for UBXN1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for UBXN1 (Q043233 ENSP000002941194) via UniProtKB, MINT, STRING, and/or I2D (see all 78)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACVR1Q047713, ENSP000002636404I2D: score=3 STRING: ENSP00000263640
    AMFRQ9UKV53, ENSP000002906494I2D: score=3 STRING: ENSP00000290649
    VCPP550723, ENSP000003517774I2D: score=3 STRING: ENSP00000351777
    BABAM1Q9NWV83, ENSP000003524084I2D: score=2 STRING: ENSP00000352408
    CUL1Q136163, ENSP000003268044I2D: score=2 STRING: ENSP00000326804
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031397negative regulation of protein ubiquitination IDA--
    GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process IDA--
    GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process NAS15362974

    Find genes that share ontologies with UBXN1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UBXN1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for UBXN1 gene (3 alternative transcripts): 
    NM_001286077.1  NM_001286078.1  NM_015853.4  

    Unigene Cluster for UBXN1:

    UBX domain protein 1
    Hs.351296  [show with all ESTs]
    Unigene Representative Sequence: BC032689
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000294119(uc001nuj.3) ENST00000532904(uc001nuk.3) ENST00000301935(uc001nul.2)
    ENST00000533000 ENST00000533476(uc010rme.1) ENST00000529640 ENST00000525717
    ENST00000534176 ENST00000525004 ENST00000524762 ENST00000527421 ENST00000526919
    ENST00000533908 ENST00000528907(uc010rmf.2) ENST00000531056 ENST00000436354
    ENST00000531625
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate UBXN1 (see all 15):
    hsa-miR-520f hsa-miR-588 hsa-miR-148b hsa-miR-922 hsa-miR-548s hsa-miR-374a* hsa-miR-223 hsa-miR-152
    SwitchGear 3'UTR luciferase reporter plasmidUBXN1 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat UBXN1
      QuantiFast Probe-based Assays in human, mouse, rat UBXN1

    Additional mRNA sequence: 

    AK054832.1 AK297856.1 AK300542.1 AK303471.1 AK316012.1 BC000902.2 BC001372.2 BC032689.1 
    BC040129.1 M68864.1 

    15 DOTS entries:

    DT.92451841  DT.97857059  DT.100883758  DT.317656  DT.95372095  DT.120701319  DT.100883768  DT.120701309 
    DT.100883762  DT.100837972  DT.100883755  DT.120701294  DT.91642459  DT.100883728  DT.95372086 

    Selected AceView cDNA sequences (see all 521):

    BC001372 BQ478223 CD518261 CD674473 BM694302 BX396465 CR626110 BC040129 
    BM716780 BX358073 CD743097 BX280774 CD106939 BQ950014 CR603413 BU631386 
    BG741404 BM664206 AI347485 BU535445 BM761934 W74075 CD674474 CA495320 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UBXN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCGGCCTC
    UBXN1 Expression
    About this image


    UBXN1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 17) fully expand
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    UBXN1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UBXN1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.351296
        Custom PCR Arrays for UBXN1
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for UBXN1 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ubxn11 , 5 UBX domain protein 11, 5 88.66(n)1
    92.93(a)1
      19 (5.88 cM)5
    2258961  NM_146093.11  NP_666205.11 
     88715595 
    lizard
    (Anolis carolinensis)
    Reptilia UBXN16
    UBX domain protein 1
    67(a)
    1 ↔ 1
    GL344296.1(800-11828)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.14962 Xenopus laevis transcribed sequence with weak similarity more 72.11(n)    BU907420.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CA975614.12   -- 73.31(n)    CA975614.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG82091 CG8209 50.85(n)
    45.29(a)
      38888  NM_139910.4  NP_648167.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ubxn-11 ubxn-1   --   171804  NM_058577.4  NP_490978.1 


    ENSEMBL Gene Tree for UBXN1 (if available)
    TreeFam Gene Tree for UBXN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UBXN1 gene
    UBXN42  

    Find genes that share paralogs with UBXN1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UBXN1 (see all 147)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1925607051,2
    --62443482(+) CCAAGC/GCAGGC 1 -- int10--------
    rs1845477881,2
    --62443486(+) GGCAGC/GCGAAT 1 -- int10--------
    rs1894682611,2
    --62443492(+) CGAATC/GACAAG 1 -- int10--------
    rs1923012271,2
    --62443503(+) GTCAGA/GAGTTT 1 -- int10--------
    rs1850231841,2
    --62443669(+) ATTGCA/GCCACT 1 -- int10--------
    rs1894837971,2
    --62443774(+) TAAAAC/GGTGCC 1 -- int10--------
    rs1502542121,2
    --62443984(+) CTCAGC/GGTCTA 1 -- ut310--------
    rs1122939441,2
    C--62444113(+) AGTCCA/C/TGAAGA 2 -- ut311CSA 1
    rs1120619351,2
    C--62444114(+) GTCCTA/C/GAAGAT 2 -- ut311CSA 1
    rs2018981441,2
    --62444144(+) CCACAA/GGGATA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for UBXN1 (62443970 - 62446567 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for UBXN1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv897623CNV Loss21882294
    nsv832182CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UBXN1 gene, integrated from 10 sources (see all 38):
    (articles sorted by number of sources associating them with UBXN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function. (PubMed id 20351172)1, 2, 3 Wu-Baer F.... Baer R. (Mol. Cell. Biol. 2010)
    2. UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. (PubMed id 18775313)1, 2 Alexandru G....Deshaies R.J. (Cell 2008)
    3. A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs. (PubMed id 15362974)1, 2 McNeill H.... Cohen P. (Biochem. J. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Human and mouse proteases: a comparative genomic approach. (PubMed id 12838346)1, 3 Puente X.S.... Lopez-Otin C. (Nat. Rev. Genet. 2003)
    6. A novel protein specifically interacting with Homer2 regulates ubiquitin-proteasome systems. (PubMed id 15944415)1, 9 Ishibashi T....Sugiyama H. (J. Biochem. 2005)
    7. The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. (PubMed id 23463506)1 Perez-Hernandez D....YA!A+ez-MA^ M. (J. Biol. Chem. 2013)
    8. UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS. (PubMed id 23545497)1 Wang P....Sutton R.E. (Cell Rep 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51035 HGNC: 18402 AceView: LOC51035 Ensembl:ENSG00000162191 euGenes: HUgn51035
    ECgene: UBXN1 H-InvDB: UBXN1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UBXN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UBXN1 gene:
    Search GeneIP for patents involving UBXN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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