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Aliases for UBTD1 Gene

Aliases for UBTD1 Gene

  • Ubiquitin Domain Containing 1 2 3

External Ids for UBTD1 Gene

Summaries for UBTD1 Gene

Entrez Gene Summary for UBTD1 Gene

  • The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]

GeneCards Summary for UBTD1 Gene

UBTD1 (Ubiquitin Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is UBTD2.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBTD1 Gene

Genomics for UBTD1 Gene

Genomic Location for UBTD1 Gene

Start:
97,498,868 bp from pter
End:
97,571,209 bp from pter
Size:
72,342 bases
Orientation:
Plus strand

Genomic View for UBTD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBTD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBTD1 Gene

Regulatory Elements for UBTD1 Gene

Transcription factor binding sites by QIAGEN in the UBTD1 gene promoter:

Proteins for UBTD1 Gene

  • Protein details for UBTD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HAC8-UBTD1_HUMAN
    Recommended name:
    Ubiquitin domain-containing protein 1
    Protein Accession:
    Q9HAC8
    Secondary Accessions:
    • D3DR57
    • Q53HI3

    Protein attributes for UBTD1 Gene

    Size:
    227 amino acids
    Molecular mass:
    25938 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBTD1 Gene

Proteomics data for UBTD1 Gene at MOPED

Post-translational modifications for UBTD1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys37 and Lys50

Other Protein References for UBTD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBTD1 Gene

Domains for UBTD1 Gene

Protein Domains for UBTD1 Gene

Suggested Antigen Peptide Sequences for UBTD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9HAC8

UniProtKB/Swiss-Prot:

UBTD1_HUMAN
Domain:
  • Contains 1 ubiquitin-like domain.:
    • Q9HAC8
genes like me logo Genes that share domains with UBTD1: view

No data available for Gene Families for UBTD1 Gene

Function for UBTD1 Gene

Gene Ontology (GO) - Molecular Function for UBTD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with UBTD1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for UBTD1 Gene

Localization for UBTD1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UBTD1 Gene COMPARTMENTS Subcellular localization image for UBTD1 gene
Compartment Confidence
nucleus 2
cytosol 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for UBTD1 Gene

Pathways for UBTD1 Gene

SuperPathways for UBTD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for UBTD1 Gene

None

No data available for Pathways by source for UBTD1 Gene

Transcripts for UBTD1 Gene

mRNA/cDNA for UBTD1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(118) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for UBTD1 Gene

Ubiquitin domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for UBTD1 Gene

No ASD Table

Relevant External Links for UBTD1 Gene

GeneLoc Exon Structure for
UBTD1
ECgene alternative splicing isoforms for
UBTD1

Expression for UBTD1 Gene

mRNA expression in normal human tissues for UBTD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UBTD1 Gene

SOURCE GeneReport for Unigene cluster for UBTD1 Gene Hs.500724

genes like me logo Genes that share expressions with UBTD1: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for UBTD1 Gene

Orthologs for UBTD1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UBTD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBTD1 35
  • 99.56 (n)
  • 100 (a)
UBTD1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UBTD1 35
  • 93.83 (n)
  • 98.68 (a)
UBTD1 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UBTD1 35
  • 93.33 (n)
  • 98.54 (a)
UBTD1 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ubtd1 35
  • 90.9 (n)
  • 98.68 (a)
Ubtd1 16
Ubtd1 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UBTD1 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ubtd1 35
  • 92.66 (n)
  • 99.12 (a)
chicken
(Gallus gallus)
Aves UBTD1 35
  • 81.86 (n)
  • 83.72 (a)
UBTD1 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UBTD1 36
  • 83 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ubtd1 35
  • 72.37 (n)
  • 78.24 (a)
zebrafish
(Danio rerio)
Actinopterygii ubtd1a 36
  • 67 (a)
OneToMany
ubtd1b 35
  • 69.79 (n)
  • 74.55 (a)
ubtd1b 36
  • 73 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG1172 36
  • 44 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G45740 35
  • 52.22 (n)
  • 50 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8466 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5948 36
  • 52 (a)
OneToMany
Species with no ortholog for UBTD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UBTD1 Gene

ENSEMBL:
Gene Tree for UBTD1 (if available)
TreeFam:
Gene Tree for UBTD1 (if available)

Paralogs for UBTD1 Gene

Paralogs for UBTD1 Gene

Selected SIMAP similar genes for UBTD1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with UBTD1: view

Variants for UBTD1 Gene

Sequence variations from dbSNP and Humsavar for UBTD1 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs946983 -- 97,502,837(+) TGCGt(A/G)tgtgt intron-variant
rs946984 -- 97,515,599(+) AAACC(C/T)TGTTA intron-variant
rs946985 -- 97,515,623(+) TCTCA(G/T)CTCTG intron-variant
rs946986 -- 97,515,846(+) GGGGT(C/G)ACACG intron-variant
rs946987 -- 97,516,351(+) TCGGC(A/G)TGTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UBTD1 Gene

Variant ID Type Subtype PubMed ID
nsv7508 CNV Loss 18451855
esv1218822 CNV Deletion 17803354
esv992861 CNV Deletion 20482838
nsv7509 CNV Insertion 18451855

Relevant External Links for UBTD1 Gene

HapMap Linkage Disequilibrium report
UBTD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBTD1 Gene

Disorders for UBTD1 Gene

No disorders were found for UBTD1 Gene.

No data available for UniProtKB/Swiss-Prot for UBTD1 Gene

Publications for UBTD1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for UBTD1 Gene

Sources for UBTD1 Gene

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