Aliases for UBQLNL Gene
External Ids for UBQLNL Gene
- HGNC: 28294
- Entrez Gene: 143630
- Ensembl: ENSG00000175518
- UniProtKB: Q8IYU4
Previous GeneCards Identifiers for UBQLNL Gene
- GC11M005511
- GC11M005514
- GC11M005517
- GC11M005520
- GC11M005527
- GC11M005535
- GC11M005193
Summaries for UBQLNL Gene
GeneCards Summary for UBQLNL Gene
UBQLNL (Ubiquilin-Like) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum. An important paralog of this gene is UBQLN3.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBQLNL Gene
Genomics for UBQLNL Gene
Regulatory Elements for UBQLNL Gene
Enhancers for UBQLNL Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around UBQLNL on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for UBQLNL Gene
- Chromosome:
- 11
- Start:
- 5,514,393 bp from pter
- End:
- 5,516,726 bp from pter
- Size:
- 2,334 bases
- Orientation:
- Minus strand
Genomic View for UBQLNL Gene
Genes around UBQLNL on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.4 by Ensembl
- 11p15.4 by Entrez Gene
- 11p15.4 by HGNC
UBQLNL Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for UBQLNL Gene
Proteins for UBQLNL Gene
-
Protein details for UBQLNL Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IYU4-UBQLN_HUMAN
- Recommended name:
- Ubiquilin-like protein
- Protein Accession:
- Q8IYU4
- Q6ZRU1
- Q96EK3
- Q96MB0
Protein attributes for UBQLNL Gene
- Size:
- 475 amino acids
- Molecular mass:
- 52897 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAC87218.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA.; Evidence={ECO:0000305};
Post-translational modifications for UBQLNL Gene
Other Protein References for UBQLNL Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for UBQLNL
- Novus Biologicals Antibodies for UBQLNL
- GeneTex UBQLNL antibody for UBQLNL
-
Santa Cruz Biotechnology (SCBT) Antibodies for UBQLNL
Protein Products
-
OriGene Purified Proteins for UBQLNL
- Search Origene for MassSpec and Protein Over-expression Lysates for UBQLNL
- Origene Custom Protein Services for UBQLNL
- Search GeneTex for Proteins for UBQLNL
Assay Products
No data available for DME Specific Peptides for UBQLNL Gene
Domains & Families for UBQLNL Gene
Gene Families for UBQLNL Gene
- HGNC:
Protein Domains for UBQLNL Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for UBQLNL Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IYU4- Domain:
-
- Contains 1 ubiquitin-like domain.
Function for UBQLNL Gene
Phenotypes for UBQLNL Gene
- GenomeRNAi human phenotypes for UBQLNL:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for UBQLNL gene
-
ViGene Biosciences ready-to-package AAV shRNAs for UBQLNL gene
- Search ViGene Biosciences for UBQLNL
CRISPR Products
-
OriGene CRISPR knockouts for UBQLNL
-
Santa Cruz Biotechnology (SCBT) CRISPR for UBQLNL
- GenScript: Design CRISPR guide RNA sequences for UBQLNL
miRNA for UBQLNL Gene
- miRTarBase miRNAs that target UBQLNL
miRNA Products
- Search ViGene Biosciences for UBQLNL
Clone Products
- OriGene clones in human for UBQLNL
- OriGene ORF clones in human,mouse,rat for UBQLNL
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for UBQLNL gene
-
ViGene Biosciences lentiviral particle packaged cDNA for UBQLNL gene
-
ViGene Biosciences ready-to-package AAV shRNAs for UBQLNL gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UBQLNL Gene
Localization for UBQLNL Gene
| Compartment | Confidence |
|---|---|
| cytosol | 2 |
| mitochondrion | 2 |
| nucleus | 1 |
| peroxisome | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for UBQLNL Gene
Pathways & Interactions for UBQLNL Gene
More details on SuperPathways for UBQLNL| Superpath | Contained pathways | |
|---|---|---|
| 1 | Protein processing in endoplasmic reticulum |
Pathways by source for UBQLNL Gene
1 KEGG pathway for UBQLNL Gene
Interacting Proteins for UBQLNL Gene
No data available for SIGNOR curated interactions for UBQLNL Gene
Transcripts for UBQLNL Gene
mRNA/cDNA for UBQLNL Gene
- (1) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (17) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for UBQLNL
-
Santa Cruz Biotechnology (SCBT) CRISPR for UBQLNL
- GenScript: Design CRISPR guide RNA sequences for UBQLNL
miRNA Products
- Search ViGene Biosciences for UBQLNL
Clone Products
- OriGene clones in human for UBQLNL
- OriGene ORF clones in human,mouse,rat for UBQLNL
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for UBQLNL Gene
mRNA differential expression in normal tissues according to GTEx for UBQLNL Gene
This gene is overexpressed in Testis (x26.0).
SOURCE GeneReport for Unigene cluster for UBQLNL Gene Hs.10688
Primer Products
-
OriGene qPCR primer pairs for UBQLNL
-
OriGene qPCR primer pairs and template standards for UBQLNL
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for UBQLNL Gene
Orthologs for UBQLNL Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | UBQLNL 35 |
|
||
| UBQLNL 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | UBQLNL 35 |
|
||
| UBQLNL 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Ubqlnl 35 |
|
||
| Ubqlnl 16 |
|
||||
| Ubqlnl 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | UBQLNL 35 |
|
||
| UBQLNL 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Ubqlnl 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | UBQLNL 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | -- 36 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 36 |
|
OneToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG31528 36 |
|
ManyToMany | |
| Ubqn 36 |
|
ManyToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | ubql-1 36 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | DSK2 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10824 36 |
|
OneToMany |
- Species with no ortholog for UBQLNL:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- zebrafish (Danio rerio)
Paralogs for UBQLNL Gene
Variants for UBQLNL Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_036652 | - | ||||
| VAR_036653 | - | ||||
| VAR_036654 | - | ||||
| VAR_036655 | - | ||||
| VAR_036656 | - |
Residual Variation Intolerance Score:
94.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.73;
73.30% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for UBQLNL Gene
Disorders for UBQLNL Gene
Relevant External Links for UBQLNL
No disorders were found for UBQLNL Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBQLNL Gene
Publications for UBQLNL Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
Products for UBQLNL Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for UBQLNL
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for UBQLNL
- Search Origene for MassSpec and Protein Over-expression Lysates for UBQLNL
- Origene Custom Protein Services for UBQLNL
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for UBQLNL
- Browse OriGene Inhibitory RNA Products For UBQLNL
- OriGene qPCR primer pairs for UBQLNL
- OriGene qPCR primer pairs and template standards for UBQLNL
- OriGene CRISPR knockouts for UBQLNL
- OriGene clones in human for UBQLNL
- OriGene ORF clones in human,mouse,rat for UBQLNL
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for UBQLNL
- GenScript Custom Assay Services for UBQLNL
- GenScript Custom overexpressing Cell Line Services for UBQLNL
- GenScript: Design CRISPR guide RNA sequences for UBQLNL
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for UBQLNL
- Novus Biologicals Antibodies for UBQLNL
- Novus Biologicals proteins and lysates for UBQLNL
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for UBQLNL gene
- ViGene Biosciences lentiviral particle packaged cDNA for UBQLNL gene
- ViGene Biosciences lentiviral particle packaged cDNA for UBQLNL gene
- ViGene Biosciences ready-to-package AAV shRNAs for UBQLNL gene
- ViGene Biosciences ready-to-package AAV shRNAs for UBQLNL gene
- ViGene Biosciences ready-to-package AAV shRNAs for UBQLNL gene
- Search ViGene Biosciences for UBQLNL
- Search ViGene Biosciences for UBQLNL
- Santa Cruz Biotechnology (SCBT) Antibodies for UBQLNL
- Search Santa Cruz Biotechnology (SCBT) for UBQLNL siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for UBQLNL
Sources for UBQLNL Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon