UBQLN4 Gene
protein-coding GIFtS: 53
GCID: GC01M156005
|
|
ubiquilin 4(Previous name: chromosome 1 open reading frame 6 )
(Previous symbol: C1orf6)
| |
Aliases
for UBQLN4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquilin 41 2 | | Connexin43-Interacting Protein Of 75 KDa2 3 | | C1orf61 2 3 5 | | A1Up2 3 | | UBIN1 2 3 | | CIP752 3 | | A1U1 2 5 | | Chromosome 1 Open Reading Frame 61 | | Ataxin-1 Interacting Ubiquitin-Like Protein2 3 | | Ataxin-1 Ubiquitin-Like Interacting Protein2 | | Ataxin-1 Ubiquitin-Like-Interacting Protein A1U2 3 | | Ubiquilin-41 |
Export aliases for UBQLN4 gene to outside databasesPrevious GC identifers: GC00U920633 GC01M152819 GC01M154271 GC01M127367 |
Summaries
for UBQLN4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: UBQL4_HUMAN, Q9NRR5Function: Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote orinhibit proteasomal protein degradation
|
Genomic Views
for UBQLN4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBQLN4 gene promoter:
Pax-5 MIF-1 Nkx2-5 AP-2gamma Tal-1beta GATA-1 HEN1 Pax-3 Sox9 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBQLN4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBQLN4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21 Ensembl cytogenetic band: 1q22 HGNC cytogenetic band: 1q21UBQLN4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M156005: view genomic region
(about GC identifiers)
Start:
|
156,005,092 bp from pter |
End:
|
156,023,585 bp from pter |
Size:
|
18,494 bases |
Orientation:
|
minus strand |
|
Proteins
for UBQLN4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBQL4_HUMAN, Q9NRR5 (See
protein sequence)Recommended Name: Ubiquilin-4 Size: 601 amino acids; 63853 Da
Subunit: Binds signal sequences of proteins that are targeted to the endoplasmic reticulum. Interacts (via UBA domain)with GJA1 (not ubiquitinated) and with ubiquitin; both compete for the same binding site (By similarity). Homodimer.Interacts (via UBA domain) with ubiquitin and with polyubiquitin chains. Interacts (via ubiquitin-like domain) withPSMD4, a regulatory subunit of the 26S proteasome. Interacts with ATXN1/SCA1. Interaction with ATXN1 inhibitspolyubiquitination of UBQLN4 and interferes with PSMD4 binding
Subcellular location: Nucleus. Cytoplasm. Endoplasmic reticulum (Probable). Cytoplasm, perinuclear region (Bysimilarity). Note=Colocalizes with the proteasome, both in nucleus and cytoplasm. May associate with the endoplasmicreticulum
Sequence caution: Sequence=AAF19084.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=AAH06410.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6ND44 B2RAY7 Q5VYA0 Q5VYA1 Q9BR98 Q9UHX4Alternative splicing: 2 isoforms: Q9NRR5-1 Q9NRR5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBQLN4: NX_Q9NRR5
Post-translational modifications:
Ubiquitinated; this does not lead to proteasomal degradation. May undergo both 'Lys-48'- and 'Lys-63'-linkedpolyubiquitination1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRR5
UBQLN4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_064516.2
ENSEMBL proteins: ENSP00000357292 ENSP00000357290
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
UBQLN4 for ontologies About GeneDecksing
UBQLN4 Antibody Products:
Assay Products for UBQLN4: |
Protein
Domains /
Families
for UBQLN4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBQLN4 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q9NRR5ProtoNet protein and cluster: Q9NRR5 2 Blocks protein families: IPB000449 Ubiquitin-associated domain IPB000626 Ubiquitin domain
UniProtKB/Swiss-Prot: UBQL4_HUMAN, Q9NRR5Similarity: Contains 1 UBA domainSimilarity: Contains 1 ubiquitin-like domain |
Function
for UBQLN4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBQL4_HUMAN, Q9NRR5Function: Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote orinhibit proteasomal protein degradation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBQLN4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBQLN4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UBQLN4 (NM_020131) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBQLN4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBQLN4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBQLN4 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
UBQLN4 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for UBQLN4:
|
Pathways & Interactions
for UBQLN4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for UBQLN4):
UBQLN4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBQLN4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/230 Interacting proteins for UBQLN4 (Q9NRR51, 2, 3 ENSP000003572924) via UniProtKB, MINT, STRING, and/or I2D (see all 230)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| PDLIM7 | Q9NR121, 2, 3, ENSP000003480994 | EBI-722657,EBI-2556830 MINT-2866276 I2D:
score=3 STRING: ENSP00000348099 | | TRIM32 | Q130491, 2, 3, ENSP000003630954 | EBI-722657,EBI-742790 MINT-2870049 I2D:
score=3 STRING: ENSP00000363095 | | ZNF205 | O952011, 2, 3, ENSP000002190914 | EBI-722657,EBI-747343 MINT-2864265 I2D:
score=3 STRING: ENSP00000219091 | | ANKRD13D | Q6ZTN62, 3, ENSP000003108744 | MINT-2879367 MINT-2879386 I2D:
score=3 STRING: ENSP00000310874 | | AREG | P155142, 3, ENSP000002644874 | MINT-2856981 I2D:
score=3 STRING: ENSP00000264487 |
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process |
IMP | 15280365 |
UBQLN4 for ontologies About GeneDecksing
|
Drugs & Compounds
for UBQLN4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBQLN4
Search CenterWatch for drugs/clinical trials and news about UBQLN4 / UBQL4
|
Transcripts
for UBQLN4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBQLN4 gene: NM_020131.3 Unigene Cluster for UBQLN4: Ubiquilin 4 Hs.283739 [show with all ESTs]Unigene Representative Sequence: BC0638414 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000368309(uc001fna.3 uc010pgx.2) ENST00000368307 ENST00000459954
ENST00000472638
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBQLN4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBQLN4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UBQLN4 (NM_020131) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBQLN4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBQLN4 |
Additional cDNA sequence: AB209566.1 AF113544.1 AK098368.1 AK302895.1 AK314413.1 BC006410.1 BC018403.2 BC063841.1 13 DOTS entries: DT.214071 DT.101981956 DT.120849768 DT.97859907 DT.95153030 DT.120871086 DT.100794412 DT.95173913 DT.100794408 DT.121330596 DT.95173914 DT.95173916 DT.100031376 24/247 AceView cDNA sequences (see all 247): AA878060 BM773028 BX353255 BM451303 BE408334 BQ052838 BM725568 BM723400 CD671884 AI637923 AI656602 AW275065 AK098368 BX345281 BM762843 BQ276398 CR625574 BM760774 BQ219477 BE297586 CR617278 BM014051 F29863 CB155717
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for UBQLN4 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UBQLN4
|
Expression
for UBQLN4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBQLN4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGAGAATA
About this image
See UBQLN4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBQLN4
SOURCE GeneReport for Unigene cluster: Hs.283739
UniProtKB/Swiss-Prot: UBQL4_HUMAN, Q9NRR5Tissue specificity: Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lowerlevels in placenta, lung and liver
SABiosciences Custom PCR Arrays for UBQLN4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBQLN4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UBQLN4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBQLN4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBQLN4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBQLN4 |
Orthologs
for UBQLN4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBQLN4 gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
UBQLN41 |
ubiquilin 4 |
78.92(n)
85.33(a) |
|
426353 NM_001031373.1 NP_001026544.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
ubin-pending-prov2 |
chromosome 1 open reading frame 6 |
80.08(n) |
|
BC047982.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb48e112 |
Danio rerio cDNA clone MGC66188 IMAGE5605506, complete more |
79.3(n) |
|
BC055536.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Ubqn6CG315286 |
-- |
48(a)24(a) |
1 ↔ manypossible ortholog |
X(19577781-19581273) 3R(242160-243387) |
worm
(Caenorhabditis elegans) |
Secernentea |
F15C11.26 |
F15C11.2 |
36(a) |
1 → many |
I(7021981-7029075) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G171906DSK26 |
ubiquitin-like protein |
33(a)31(a) |
many ↔ manymany ↔ many |
2(7477845-7481606) 2(7481881-7485240) |
rice
(Oryza sativa) |
Liliopsida |
---- |
ubiquitin family protein, putative, expressed |
31(a)26(a) |
many ↔ manymany ↔ many |
3(1790568-1795419) 10(21097813-21103066) |
ENSEMBL Gene Tree for UBQLN4 (if available)
TreeFam Gene Tree for UBQLN4 (if available) |
Paralogs
for UBQLN4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBQLN4 gene
- UBQLN32 UBQLN22 UBQLN12 UBQLNL2
3 SIMAP similar genes for UBQLN4 using alignment to 2 protein entries: UBQL4_HUMAN (see all proteins):UBQLN1 UBQLN2 UBQLN3
UBQLN4 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for UBQLN4
PGOHUM00000240987
|
Genomic Variants
for UBQLN4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBQLN4 (156005092 - 156023585 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for UBQLN4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBQLN4 |
|
Disorders
/ Diseases
for UBQLN4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBQLN4 for disorders About GeneDecksing
OMIM gene information: 605440
OMIM disorders: --
3  diseases for UBQLN4: About MalaCardsmumps ataxia malaria
Human Genome Epidemiology (HuGE) Navigator: UBQLN4 (1 document)
Export disorders for UBQLN4 gene to outside databases
|
Publications
for UBQLN4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBQLN4 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with UBQLN4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein. (PubMed id 11001934)1, 2, 3, 9 Davidson J.D....Orr H.T. (2000)
- Identification of two paralogous regions mapping to the short and long arms of human chromosome 2 comprising LIS1 pseudogenes. (PubMed id 10575211)1, 2, 3 Fogli A.... Carrozzo R. (1999)
- The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up. (PubMed id 15280365)1, 2, 9 Riley B.E....Orr H.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for UBQLN4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBQLN4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBQLN4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBQLN4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBQLN4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBQLN4 gene:
Search GeneIP for patents involving UBQLN4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBQLN4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for UBQLN4 | | OriGene shRNA RFP for UBQLN4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBQLN4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBQLN4 | | | OriGene Protein Over-expression Lysate for UBQLN4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBQLN4 | | OriGene 3'-UTR Clone for UBQLN4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBQLN4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBQLN4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for UBQLN4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBQLN4 | | OriGene Custom Protein Services for UBQLN4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBQLN4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBQLN4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBQLN4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBQLN4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBQLN4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBQLN4 |
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| | | | Search Tocris compounds for UBQLN4 |
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 | | | UBQLN4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBQLN4 |
|  |  |  | | | | ThermoFisher Antibodies for UBQLN4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBQLN4 |
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