V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

UBQLN1 Gene

protein-coding   GIFtS: 62

GC09M085464
ubiquilin 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
DA41 1, 2, 3, 5
DSK2 1, 2
FLJ90054 2
OTTHUMP00000021544 2
OTTHUMP00000021545 2
PLIC-1 1, 2, 3
PLIC1 3
UBQN 2
XDRP1 1, 2
hPLIC-1 3
Descriptions
Protein linking IAP with cytoskeleton 1 3
ubiquilin 1 2
External Ids
HGNC: 125081
Entrez Gene: 299792
UniProtKB: Q9UMX03
Ensembl: ENSG000001350187
Search outside databases for aliases for UBQLN1 gene

Previous GC identifers: GC09M077319 GC09M078129 GC09M079829 GC09M081731 GC09M081732 GC09M083504

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for UBQLN1:
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity
with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like
domain and a C-terminal ubiquitin-associated domain. They physically associate with both
proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination
machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been
shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with
Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms
have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: UBQL1_HUMAN, Q9UMX0
Function: Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By
similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their
biosynthesis. Has no effect on PSEN1 and PSEN2 degradation

Gene Wiki entry for UBQLN1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the UBQLN1 gene  

Entrez Gene cytogenetic band: 9q22|9q21.2-q21.3   Ensembl cytogenetic band:  9q21.32   HGNC cytogenetic band: 9q22

UBQLN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M085464:     (about GC identifiers)

Start:
85,464,699 bp from pter
End:
85,512,773 bp from pter
Size:
48,075 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000009.10  NT_023935.17  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: UBQL1_HUMAN, Q9UMX0 (See protein sequence)
Recommended Name: Ubiquilin-1  
Size: 589 amino acids; 62519 Da
Subunit: Binds CD47, NBL1, GABRA1, GABRA2, GABRA3, GABRA6, GABRB1, GABRB2 and GABRB3 (By
similarity). Binds UBE3A, BTRC, P4HB, FRAP1, PSEN1 and PSEN2. Interacts with the proteasome 19S
subunit
Subcellular location: Cytoplasm. Nucleus
PDB structure from and Proteopedia :
2JY5 (3D)    2JY6 (3D)    
Secondary accessions: Q8IXS9 Q8N2Q3 Q9H0T8 Q9H3R4 Q9HAZ5
Alternative splicing: 2 isoforms:  Q9UMX0-1   Q9UMX0-2   

Post-translational modifications:

  • Phosphorylated1
  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins (2 alternative transcripts): 
    NP_038466.2  NP_444295.1  


    ENSEMBL proteins: 
    ENSP00000365576 ENSP00000257468 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for UBQLN1
    Recombinant Proteins from Abcam (Ubiquilin)
    Human Recombinant Proteins from Abnova (UBQLN1)
                  OriGene Purified Recombinant Human Protein: UBQLN1 

    5 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005737 cytoplasm IDA11853878
    GO:0005829 cytosol IEA--
    GO:0043234 protein complex IEA--
    GO:0048471 perinuclear region of cytoplasm NAS11853878
    About this table

    Antibodies for UBQLN1: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for UBQLN1
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Ubiquilin), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (UBQLN1)
    Novus Biologicals Antibodies for UBQLN1

    Assays for UBQLN1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    5/7 InterPro domains/families (see all 7 ):
     IPR019954 Ubiquitin_CS
     IPR015496 Ubiquilin
     IPR000626 Ubiquitin
     IPR019955 Ubiquitin_supergroup
     IPR006636 STI1_HS_bd


       GeneDecks  UBQLN1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q9UMX0

    ProtoNet protein and cluster: Q9UMX0

    2 Blocks protein families:
    IPB000449 Ubiquitin-associated domain
    IPB000626 Ubiquitin domain


    UniProtKB/Swiss-Prot: UBQL1_HUMAN, Q9UMX0
    Domain: Binds PSEN1 and PSEN2 via its UBA domain
    Similarity: Contains 1 UBA domain
    Similarity: Contains 1 ubiquitin-like domain

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (UBQLN1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (UBQLN1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_013438

                  Applied Biosystems Silencer® siRNAs for UBQLN1

                  Sigma-Aldrich siRNA and siRNA Panels for UBQLN1  
                         Sigma-Aldrich shRNA Panels and shRNA for UBQLN1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for UBQLN1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_013438
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_013438
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_013438 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_013438

    UniProtKB/Swiss-Prot: UBQL1_HUMAN, Q9UMX0
    Function: Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By
    similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their
    biosynthesis. Has no effect on PSEN1 and PSEN2 degradation

    1 Gene Ontology (GO) molecular function term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0019900 kinase binding IPI11853878
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  UBQLN1  (Your Favorite Gene powered by Ingenuity) 
     GABA Receptor Signaling

       GeneDecks  UBQLN1 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  UBQLN1 


    5/40 Interacting proteins for UBQLN1 (ENSP000003655763 Q9UMX02) via UniProtKB, MINT, and/or STRING (see all 40 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EPS15P425662STRING (score=.773) MINT-4300195 MINT-4300120 MINT-4302859 MINT-4302787 MINT-4302826
    PSEN1P497682STRING (score=.983) MINT-16889 MINT-16890 MINT-16888
    PSEN2P498102STRING (score=.98) MINT-17616 MINT-17615 MINT-17617
    ATXN3P542522STRING (score=.73) MINT-4300171 MINT-4300075
    PSMD4P550362STRING (score=.782) MINT-4300148
    About this table

    1 Gene Ontology (GO) biological process term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006464 protein modification process IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for UBQLN1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (UBQLN1)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (UBQLN1)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_013438

                  Sigma-Aldrich siRNA and siRNA Panels for UBQLN1  
                         Sigma-Aldrich shRNA Panels and shRNA for UBQLN1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_013438  NM_053067  

    REFSEQ mRNAs for UBQLN1 gene (2 alternative transcripts): 

    NM_013438.4   NM_053067.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_013438  NM_053067  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_013438
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_013438
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_013438 

    Additional cDNA sequence: 

    AB035275.1 AB209468.1 AF176069.3 AF293384.1 AK027556.1 AK027576.1 AK074535.1 AK125815.1 
    AL136643.1 BC010066.2 BC039294.1 CR596552.1 CR612259.1 

    14 DOTS entries:

    DT.100036812  DT.443588  DT.100036814  DT.100825284  DT.40118719  DT.40241331  DT.121201647  DT.92448341 
    DT.95173203  DT.100825281  DT.121201600  DT.121201624  DT.92448346  DT.95173192 

    24/426 AceView cDNA sequences (see all 426 ):

    AV725590 AA749374 BF590799 AI738847 BE219910 AI989901 CD106908 BG387774 
    AW474532 AI701397 BG528770 BE672920 AW572006 AI738564 N90838 AI568787 
    NM_013438 Z17365 BQ008742 CA432340 CD679359 AI796994 AI658751 AA021505 

    highest scoring ESTs for UBQLN1:

    AI244901 AA016215 AA021506 AA037649 AA160015 AA313336 AA452806 AA576689 AA749374 AA758246 

    Unigene Cluster for UBQLN1:

    Ubiquilin 1
    Hs.9589  [show with all ESTs]
    Unigene Representative Sequence: AB209468


    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for UBQLN1

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b
    SP1:                                                              -           -                     
    SP2:                                                        -     -           -                     
    SP3:              -     -     -                                                                     
    SP4:                                                                          -                     
    SP5:                                                                                                

    About this scheme

    ECgene alternative splicing isoforms for UBQLN1

    2 Ensembl transcripts including schematic representations:
    ENST00000376395  ENST00000257468  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    UBQLN1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for UBQLN1

    1 / 2 / 3

    9 probe-sets matching UBQLN1 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    82573_at2, 3 U95-E 1 1.00 1.00 0.87 1.08 AI244901 1.00 1.00 1.00 1

    46707_at2, 3 U95-B 1 1.00 1.00 0.32 1.12 N90555 0.80 1.00 0.91 1

    57914_at2, 3 U95-B 1 0.88 1.00 0.93 0.79 W52859 0.80 1.00 0.91 1

    222991_s_at2, 3 U133-B 1 1.00 1.00 -- -- AL136643 0.80 0.88 0.84 1

    222989_s_at2, 3 U133-B 1 1.00 1.00 -- -- NM_013438 0.60 1.00 0.82 1

    222990_at2, 3 U133-B 1 1.00 1.00 -- -- AW204104 0.60 1.00 0.82 1

    222991_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    222989_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    222990_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TGTCTTTGCT

    SOURCE GeneReport for Unigene cluster: Hs.9589

    UniProtKB/Swiss-Prot: UBQL1_HUMAN, Q9UMX0
    Tissue specificity: Ubiquitous. Highly expressed throughout the brain; detected in neurons and in
    neuropathological lesions, such as neurofibrillary tangles and Lewy bodies. Highly expressed in
    heart, placenta, pancreas, lung, liver, skeletal muscle and kidney

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for UBQLN1 gene from 5/11 species (see all 11 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    UBQLN11   -- ubiquilin 1 93.6(n)
    95.76(a)
    476312  XM_853208.1  XP_858301.1 
    cow
    (Bos taurus)
    UBQLN11   -- ubiquilin 1 92.28(n)
    94.72(a)
    282392  NM_174628.1  NP_777053.1 
    rat
    (Rattus norvegicus)
    Ubqln11   -- ubiquilin 1 84.28(n)
    88.95(a)
    114590  NM_053747.2  NP_446199.2 
    mouse
    (Mus musculus)
    Ubqln11, 5 13 (35.00 cM)5
    ubiquilin 11, 5 84.45(n)1
    90.02(a)1
    560851  NM_152234.11  NP_689420.11 
     AF1773455  AI4259825  (see all 34)
    chicken
    (Gallus gallus)
    UBQLN11   -- ubiquilin 1 78.11(n)
    83.19(a)
    427454  XM_425028.2  XP_425028.2 
    About this table        Species with no ortholog for UBQLN1

    ENSEMBL Gene Tree for UBQLN1
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for UBQLN1 gene
    UBQLN32  UBQLN22  UBQLN42  UBQLNL2  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/319 NCBI SNPs in UBQLN1 are shown (see all 319 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 123)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 9 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs13338631,2
    A,C,F,H,O85513802(-) AGAAAC/GGCAGA 2 -- ng3114Minor allele frequency- G:0.30NA EA MN EU WA 1096
    rs13338651,2
    A,C,F,H,O85513416(-) CAGGTC/TGCCTG 2 -- ng3120Minor allele frequency- T:0.25NA EA MN EU WA 2922
    rs28119281,2
    A,C,F,H85464663(+) TTAAAT/GACTTT 1 -- ng514Minor allele frequency- G:0.21EU EA WA 418
    rs13338621,2
    A,C,F,H85514070(-) AATGAT/CTGGTT 2 -- ng31 tfbs314Minor allele frequency- C:0.44NA EA EU WA 1090
    rs78749801,2
    A,C,F,H85514724(+) agtaaC/Tcatag 1 -- ng314Minor allele frequency- T:0.13EU EA WA 420
    rs38145071,2
    A,C,F,H85513129(+) CTTGCC/TTCTCT 2 -- ng316Minor allele frequency- T:0.37MN EA EU WA 1670
    rs38145051,2
    A,C,F,H85512977(+) TCACGA/GTTAGC 2 -- ut51 tfbs36Minor allele frequency- G:0.44MN EA EU WA 1670
    rs123455141,2
    A,C,F,H85514246(+) ATCCTG/TTATCA 2 -- ng314Minor allele frequency- T:0.13EU EA WA 414
    rs10442141,2
    A,C,F,H85465379(-) GTCCTG/TGATGG 2 -- ut315Minor allele frequency- T:0.23MN EU EA WA 602
    rs38145061,2
    C,F,H85513094(+) CC/TTCCGC 2 -- ng313Minor allele frequency- T:0.04EA WA 298
    About this table

    HapMap Linkage Disequilibrium images for UBQLN1 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 605046

    2 Novoseek disease relationships for UBQLN1 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    alzheimers disease 68.49 18 15745979 (5), 16214290 (2), 17704509 (1), 16278862 (1) (see all 9)
    tumors 0.00 1 10807547 (1)
    About this table

    Genetic Association Database: UBQLN1
    Human Genome Epidemiology Navigator: UBQLN1 (9 documents)

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/57 PubMed articles for UBQLN1 gene (see all 57 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 29979 HGNC: 12508 AceView: UBQLN1 Ensembl:ENSG00000135018 euGenes: HUgn29979
    ECgene: UBQLN1 H-InvDB: UBQLN1
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

      --
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for UBQLN1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for UBQLN1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for UBQLN1 Antibodies for UBQLN1
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for UBQLN1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (UBQLN1)
     Antibodies (UBQLN1)
     Chimera RNAi (UBQLN1)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (Ubiquilin)
     Antibodies (Ubiquilin)
     Tagged/untagged cDNA clones
     Validated SYBR primer pairs
     Purified proteins from HEK293T cells
     Western blot validated antibodies
     shRNA in GFP-retroviral vector
     Search Tocris compounds for UBQLN1




     Proteins for UBQLN1
     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for UBQLN1

    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

    Random Gene From GIFtS : about GIFtS

    Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    UBQLN1 Gene at Home site.
    Version 2.41.1
    server5.xennexinc.com