Aliases for UBP1 Gene
External Ids for UBP1 Gene
Previous GeneCards Identifiers for UBP1 Gene
GeneCards Summary for UBP1 Gene
UBP1 (Upstream Binding Protein 1 (LBP-1a)) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription corepressor activity. An important paralog of this gene is TFCP2L1.
UniProtKB/Swiss-Prot for UBP1 Gene
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.