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UBP1 Gene

protein-coding   GIFtS: 52
GCID: GC03M033404

Upstream Binding Protein 1 (LBP-1a)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Upstream Binding Protein 1 (LBP-1a)1 2     LBP-1B2
Transcription Factor LBP-12 3     LBP-1a2
LBP1A2 5     Upstream-Binding Protein 12
LBP1B2 5     LBP13

External Ids:    HGNC: 125071   Entrez Gene: 73422   Ensembl: ENSG000001535607   OMIM: 6097845   UniProtKB: Q9NZI73   

Export aliases for UBP1 gene to outside databases

Previous GC identifers: GC03M032735 GC03M033276 GC03M033401


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UBP1 Gene:
UBP1 (upstream binding protein 1 (LBP-1a)) is a protein-coding gene. GO annotations related to this gene include transcription corepressor activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is GRHL3.

UniProtKB/Swiss-Prot: UBIP1_HUMAN, Q9NZI7
Function: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental
expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the
alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in
regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation
site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the
TATA-box

Gene Wiki entry for UBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the UBP1 gene promoter:
         MEF-2A   TBP   AP-1   ATF-2   aMEF-2   c-Jun   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for UBP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.3   Ensembl cytogenetic band:  3p22.3   HGNC cytogenetic band: 3p22.3

UBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBP1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M033404:  view genomic region     (about GC identifiers)

Start:
33,429,828 bp from pter      End:
33,482,863 bp from pter
Size:
53,036 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: UBIP1_HUMAN, Q9NZI7 (See protein sequence)
Recommended Name: Upstream-binding protein 1  
Size: 540 amino acids; 60491 Da
Subunit: Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and
PIAS1 (By similarity)
Secondary accessions: Q68CT0 Q86Y57 Q9H8V0 Q9UD76 Q9UD78
Alternative splicing: 2 isoforms:  Q9NZI7-1   Q9NZI7-4   

Explore the universe of human proteins at neXtProt for UBP1: NX_Q9NZI7

Explore proteomics data for UBP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See UBP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001121632.1  NP_001121633.1  NP_055332.3  

    ENSEMBL proteins: 
     ENSP00000283629   ENSP00000395558   ENSP00000283628   ENSP00000393842   ENSP00000401614  

    UBP1 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for UBP1
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    Novus Biologicals UBP1 Protein
    Novus Biologicals UBP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UBP1

     
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    Abcam antibodies for UBP1 (Q9NZI7, Q86Y57)
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR007604 CP2
     IPR013761 SAM/pointed

    Graphical View of Domain Structure for InterPro Entry Q9NZI7

    ProtoNet protein and cluster: Q9NZI7

    1 Blocks protein domain: IPB001660 Sterile alpha motif SAM

    UniProtKB/Swiss-Prot: UBIP1_HUMAN, Q9NZI7
    Similarity: Belongs to the grh/CP2 family. CP2 subfamily


    Find genes that share domains with UBP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UBIP1_HUMAN, Q9NZI7
    Function: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental
    expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the
    alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in
    regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation
    site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the
    TATA-box
    Induction: By HIV-1 infection of lymphocytes

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8114710
    GO:0003714transcription corepressor activity TAS8114710
         
    Find genes that share ontologies with UBP1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for UBP1:
     Increased G1 DNA content  Increased number of mitotic ce 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ubp1):
     cardiovascular system  embryogenesis  growth/size/body  mortality/aging  muscle 

    Find genes that share phenotypes with UBP1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Ubp1tm1Jmc for UBP1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UBP1
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    miRNA
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    miRTarBase miRNAs that target UBP1:
    hsa-mir-34a-5p (MIRT025583), hsa-mir-182-5p (MIRT047198), hsa-mir-183-5p (MIRT025006)

    Block miRNA regulation of human, mouse, rat UBP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate UBP1 (see all 44):
    hsa-miR-193a-3p hsa-miR-449a hsa-miR-570 hsa-miR-508-3p hsa-miR-548m hsa-miR-3150b-3p hsa-miR-181b hsa-miR-193b
    SwitchGear 3'UTR luciferase reporter plasmidUBP1 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBP1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    UBIP1_HUMAN, Q9NZI7: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    cytoskeleton1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS8114710

    Find genes that share ontologies with UBP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UBP1
    Interactions:

        Search GeneGlobe Interaction Network for UBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for UBP1 (Q9NZI73 ENSP000002836284) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206454Q018603I2D: score=1 
    ENSG00000229094Q018603I2D: score=1 
    ENSG00000230336Q018603I2D: score=1 
    ENSG00000233911Q018603I2D: score=1 
    ENSG00000235068Q018603I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001525angiogenesis IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS8114710
    GO:0019079viral genome replication TAS8114710
    GO:0045892negative regulation of transcription, DNA-templated TAS8114710

    Find genes that share ontologies with UBP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for UBP1 (UBIP1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for UBP1 gene (3 alternative transcripts): 
    NM_001128160.1  NM_001128161.1  NM_014517.4  

    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283629(uc003cfq.4 uc003cfr.4 uc010hga.3) ENST00000492136
    ENST00000447368 ENST00000466441 ENST00000283628 ENST00000486388 ENST00000464787
    ENST00000411650 ENST00000490112 ENST00000467613 ENST00000481761 ENST00000456378
    ENST00000496310
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate UBP1 (see all 44):
    hsa-miR-193a-3p hsa-miR-449a hsa-miR-570 hsa-miR-508-3p hsa-miR-548m hsa-miR-3150b-3p hsa-miR-181b hsa-miR-193b
    SwitchGear 3'UTR luciferase reporter plasmidUBP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat UBP1
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    GenScript: all cDNA clones in your preferred vector: UBP1 (NM_002484)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBP1
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    OriGene qPCR primer pairs and template standards for UBP1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat UBP1
      QuantiTect SYBR Green Assays in human, mouse, rat UBP1
      QuantiFast Probe-based Assays in human, mouse, rat UBP1

    Selected AceView cDNA sequences (see all 233):

    CB145391 BI714831 BE468230 AI082293 BE669461 AL831847 BP432631 AA299061 
    BF085922 AI126984 AI336292 AA286809 BX384446 BE043066 H88344 AL133032 
    AW015715 BM460126 AW198184 AA322784 AA630956 BE047279 AI632968 BQ130929 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for UBP1 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                                                                -                                                                           
    SP2:                                                                                -                                         -                                 
    SP3:                                                                                                                                                            
    SP4:                                -     -                                         -                                                                           
    SP5:              -     -     -     -     -     -     -                             -                                                                           

    ExUns: 19 ^ 20 ^ 21 ^ 22a · 22b
    SP1:              -               
    SP2:              -               
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for UBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    UBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTCTGTAC
    UBP1 Expression
    About this image

    UBP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    UBP1 Protein Expression

    UniProtKB/Swiss-Prot: UBIP1_HUMAN, Q9NZI7
    Tissue specificity: Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for UBP1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ubp11 , 5 upstream binding protein 11, 5 91.05(n)1
    94.07(a)1
      9 (64.14 cM)5
    222211  NM_001083319.11  NP_001076788.11 
     1139309345 
    chicken
    (Gallus gallus)
    Aves UBP11 upstream binding protein 1 (LBP-1a) 82.5(n)
    89.39(a)
      428458  XM_426018.4  XP_426018.3 
    lizard
    (Anolis carolinensis)
    Reptilia UBP16
    upstream binding protein 1 (LBP-1a)
    82(a)
    1 ↔ 1
    GL343324.1(824088-879229)
    zebrafish
    (Danio rerio)
    Actinopterygii ubp11 upstream binding protein 1 (LBP-1a) 68.77(n)
    74.14(a)
      100136855  NM_001114574.2  NP_001108046.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0070651 AgaP_AGAP007065 51.78(n)
    49.24(a)
      1270039  XM_308698.4  XP_308698.4 


    ENSEMBL Gene Tree for UBP1 (if available)
    TreeFam Gene Tree for UBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for UBP1 gene
    GRHL32  GRHL12  TFCP22  GRHL22  TFCP2L12  
    3 SIMAP similar genes for UBP1 using alignment to 3 protein entries:     UBIP1_HUMAN (see all proteins):
    DKFZp564C0164    TFCP2    TFCP2L1

    Find genes that share paralogs with UBP1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for UBP1
    PGOHUM00000259226


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for UBP1 (see all 1122)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349067301,2
    C--33376745(+) TCCAT-/CTCCTCAG 3 -- int11Minor allele frequency- CTC:0.00NA 2
    rs1128603331,2
    C--33429359(+) ATCAAA/GACCAT 3 -- ds50010--------
    rs130653591,2
    C,F--33429404(+) AAATAA/CAAAAA 3 -- ds50014Minor allele frequency- C:0.25NA WA 8
    rs46789481,2
    C,A--33429526(+) CACTGC/TACTCC 3 -- ds50011Minor allele frequency- T:0.50NA 2
    rs348606411,2
    C--33429562(+) GTCTC-/AAAAAAA 3 -- ds50011Minor allele frequency- AA:0.00NA 2
    rs1809643461,2
    --33429606(+) TTAAAA/GTCTGG 3 -- ds50010--------
    rs776770471,2
    C--33429636(+) TAGTTA/TGTTAG 3 -- ds50010--------
    rs750349021,2
    C--33429649(+) AGTTAA/TTGGAA 3 -- ds50010--------
    rs1835868591,2
    --33429726(+) AACCTC/TTTACT 3 -- ds50010--------
    rs1498034711,2
    C--33429809(+) TGGGA-/TTTTTA 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for UBP1 (33429828 - 33482863 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for UBP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv10259CNV Loss18304495
    dgv1445e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing UBP1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609784    OMIM disorders: --


    Find genes that share disorders with UBP1           About GenesLikeMe

    1 Novoseek inferred disease relationship for UBP1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    immunodeficiency 49.3 2 2006421 (1), 8114710 (1)

    Genetic Association Database (GAD): UBP1

    Export disorders for UBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UBP1 gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with UBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro. (PubMed id 8114710)1, 2, 3, 9 Yoon J.-B.... Roeder R.G. (Mol. Cell. Biol. 1994)
    2. Repression of HIV-1 transcription by a cellular protein. (PubMed id 2006421)1, 2, 9 Kato H.... Roeder R.G. (Science 1991)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc. (PubMed id 10644752)1, 2 Huang N. and Miller W.L. (J. Biol. Chem. 2000)
    6. LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells. (PubMed id 15471945)1, 9 Huang N. and Miller W.L. (Mol. Endocrinol. 2005)
    7. A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro. (PubMed id 7836461)1, 9 Parada C.A....Roeder R.G. (J. Biol. Chem. 1995)
    8. Transactivation activity of LBP-1 proteins and their dimerization in living cells. (PubMed id 19751393)1, 9 Katsura A....Sogawa K. (amp 2009)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7342 HGNC: 12507 AceView: UBP1 Ensembl:ENSG00000153560 euGenes: HUgn7342
    ECgene: UBP1 H-InvDB: UBP1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for UBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for UBP1 gene:
    Search GeneIP for patents involving UBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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