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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

UBL5 Gene

protein-coding GIFtS: 53
GCID: GC19P009938

ubiquitin-like 5

Explore 8 diseases affiliated with
UBL5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ubiquitin-Like 5¹ ²
HUB1² ⁵
Beacon¹
Ubiquitin-Like Protein 5²

External Ids:	HGNC: 13736¹	Entrez Gene: 59286²	Ensembl: ENSG00000198258⁷	OMIM: 606849⁵	UniProtKB: Q9BZL1³

Export aliases for UBL5 gene to outside databases

Previous GC identifers: GC19P010060 GC19P010161 GC19P009783 GC19P009799 GC19P009766 GC19P009520

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UBL5:

This gene encodes a member of a group of proteins similar to ubiquitin. The encoded protein is not thought to degrade

proteins like ubiquitin but to affect their function through being bound to target proteins by an isopeptide bond. The

gene product has been studied as a link to predisposition to obesity based on its expression in Psammomys obesus, the

fat sand rat, which is an animal model for obesity studies. Variation in this gene was found to be significantly

associated with some metabolic traits (PMID: 15331561) but not associated with childhood obesity (PMID: 19189687).

Pseudogenes of this gene are located on chromosomes 3, 5 and 17. Multiple alternatively spliced variants, encoding the

same protein, have been identified. (provided by RefSeq, Jan 2013)

Gene Wiki entry for UBL5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011295.11

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the UBL5 gene promoter:
CREB Elk-1 Pax-5 AP-1 deltaCREB ATF-2 STAT3 c-Jun LCR-F1 E47
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UBL5 promoter sequence

Search SABiosciences Chromatin IP Primers for UBL5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBL5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2

UBL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBL5 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P009938: view genomic region (about GC identifiers)

Start:	9,938,568 bp from pter	End:	9,940,797 bp from pter
Size:	2,230 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UBL5_HUMAN, Q9BZL1 (See protein sequence)

Recommended Name: Ubiquitin-like protein 5

Size: 73 amino acids; 8547 Da

Subunit: Interacts with CLK1, CLK3 and CLK4

Subcellular location: Cytoplasm

1 PDB 3D structure from and Proteopedia for UBL5:

1P0R (3D)

Secondary accessions: Q2NL89

Explore the universe of human proteins at neXtProt for UBL5: NX_Q9BZL1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BZL1

UBL5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001041706.1 NP_077268.1

ENSEMBL proteins:

ENSP00000468656 ENSP00000351492 ENSP00000466910 ENSP00000467663

Human Recombinant Protein Products:

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	Novus Biologicals UBL5 Proteins Novus Biologicals UBL5 Lysates
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	ProSpec Recombinant Protein for UBL5
	Uscn Proteins for UBL5

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	11161819

UBL5 for ontologies About GeneDecksing

UBL5 Antibody Products:

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	Search ThermoFisher Antibodies for UBL5

Assay Products for UBL5:

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	GenScript Custom Assay Services for UBL5
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	Uscn ELISAs and CLIAs for UBL5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

UBL5 for domains About GeneDecksing

1 InterPro domain/family:

IPR000626 Ubiquitin

Graphical View of Domain Structure for InterPro Entry Q9BZL1

ProtoNet protein and cluster: Q9BZL1

1 Blocks protein family: IPB000626 Ubiquitin domain

UniProtKB/Swiss-Prot: UBL5_HUMAN, Q9BZL1

Similarity: Contains 1 ubiquitin-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 2): UBL5 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UBL5
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate UBL5
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBL5 (see all 7) OriGene shRNA RFP: UBL5 OriGene siRNA: UBL5
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for UBL5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBL5 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBL5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for UBL5
		Search LifeMap BioReagents cell lines for UBL5

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for UBL5

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

UBL5 for ontologies About GeneDecksing

6 GenomeRNAi human phenotypes for UBL5:

Decreased homologous recombina	Decreased influenza A virus in	Decreased viability of wild-ty	Increased cell death HMECs cel
Increased gamma-H2AX phosphory	Wnt reporter downregulated

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for UBL5

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/47 Interacting proteins for UBL5 (Q9BZL1^{2, 3} ENSP00000351492⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 47)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SART1	O43290²^,³, ENSP00000310448⁴	MINT-8336584 I2D: score=4 STRING: ENSP00000310448
WDR83	Q9BRX9², ENSP00000242796⁴	MINT-8337629 MINT-8332108 STRING: ENSP00000242796
CLK4	Q9HAZ1³, ENSP00000316948⁴	I2D: score=3 STRING: ENSP00000316948
CLK1	P49759³, ENSP00000326830⁴	I2D: score=2 STRING: ENSP00000326830
BUD31	P41223³, ENSP00000222969⁴	I2D: score=1 STRING: ENSP00000222969

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

UBL5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for UBL5
Search CenterWatch for drugs/clinical trials and news about UBL5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for UBL5 gene (2 alternative transcripts):

NM_001048241.2 NM_024292.3

Unigene Cluster for UBL5:

Ubiquitin-like 5

Hs.534477 [show with all ESTs]

Unigene Representative Sequence: BQ924266

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000586895 ENST00000358666(uc002mmi.2 uc002mmj.1) ENST00000590068

ENST00000589960 ENST00000593087 ENST00000588595 ENST00000588141 ENST00000589372

miRNA Products:		OriGene 3'-UTR Clone (see all 2): UBL5 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UBL5
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate UBL5
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBL5 (see all 7) OriGene shRNA RFP: UBL5 OriGene siRNA: UBL5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBL5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBL5 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBL5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): UBL5 (NM_024292)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for UBL5
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBL5

Additional cDNA sequence:

AF313915.1 AK128885.1 AK311889.1 BC007053.1 BC110839.1 BT007355.1

20 DOTS entries:

DT.97858080 DT.448016 DT.121504701 DT.100670834 DT.121504698 DT.100670832 DT.99955281 DT.91775031

DT.121504695 DT.121504693 DT.121504715 DT.121504720 DT.100670829 DT.100670833 DT.100670836 DT.121504709

DT.121504713 DT.121504727 DT.95354129 DT.97865281

24/370 AceView cDNA sequences (see all 370):

CB113914 AI719437 R98380 AI369744 BM876552 CA502897 BM784424 AA226340

CR593093 BQ421216 BP375512 CD676888 BQ221631 CD523456 BE336891 AA861810

F29996 AA010642 CB242938 BE858122 N99973 AW163422 BM693246 AA316722

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for UBL5 (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	^	2	^	3a	·	3b	^	4a	·	4b	^	5
SP1:									-						-
SP2:									-						-		-
SP3:									-						-		-
SP4:															-		-
SP5:															-		-

ECgene alternative splicing isoforms for UBL5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

UBL5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

UBL5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Renal Vesicle

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See UBL5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBL5

SOURCE GeneReport for Unigene cluster: Hs.534477

UniProtKB/Swiss-Prot: UBL5_HUMAN, Q9BZL1

Tissue specificity: Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and

lymphoblasts

SABiosciences Custom PCR Arrays for UBL5

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBL5

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for UBL5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for UBL5 gene from 6/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ubl5^{1 , 5}	ubiquitin-like 5^{1, 5}	88.58(n)¹ 100(a)¹		9 (7.60 cM)⁵ 66177¹ NM_025401.3¹ NP_079677.1¹ 20642878⁵
zebrafish (Danio rerio)	Actinopterygii	zgc:66388¹	zgc:66388	83.8(n) 94.44(a)		394116 NM_201141.1 NP_957435.1
fruit fly (Drosophila melanogaster)	Insecta	CG3450³	--	86(a)		42D1 --
worm (Caenorhabditis elegans)	Secernentea	ubl-5⁶	Ubiquitin-like protein 5	81(a)	1 ↔ 1	I(5607825-5608843)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G45180¹	ubiquitin family protein	69.91(n) 79.17(a)		823654 NM_114387.1 NP_190104.1
rice (Oryza sativa)	Liliopsida	Os12g0143150¹	hypothetical protein	73.61(n) 80.56(a)		9269502 NM_001189859.1 NP_001176788.1

ENSEMBL Gene Tree for UBL5 (if available)
TreeFam Gene Tree for UBL5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for UBL5 gene

UBL5 for paralogs About GeneDecksing

4 Pseudogenes.org Pseudogenes for UBL5
PGOHUM00000248725 PGOHUM00000237026 PGOHUM00000237642 PGOHUM00000235540

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs115403706^1,2		--	9936614(+)	`CCAGGC/TTTGTC`	2	--	us2k¹		1		WA	118
rs185308424^1,2		--	9936621(+)	`TGTCCG/TTAACC`	2	--	us2k¹		0	--	--	--	--
rs146016197^1,2		--	9936711(+)	`AAGGAC/TGGTCC`	2	--	us2k¹		0	--	--	--	--
rs190119575^1,2		--	9936821(+)	`TCGCAA/GGCATT`	2	--	us2k¹		0	--	--	--	--
rs148305413^1,2		--	9936919(+)	`AAATAC/TGTAAA`	2	--	us2k¹		0	--	--	--	--
rs150861006^1,2		--	9937045(+)	`TAAAGA/GCCGGG`	2	--	us2k¹		0	--	--	--	--
rs139295921^1,2		--	9937186(+)	`GGTGGA/GGGGCG`	2	--	us2k¹		0	--	--	--	--
rs145596503^1,2		--	9937220(+)	`GGCGGC/TTGAGG`	2	--	us2k¹		0	--	--	--	--
rs12461515^1,2	C,F,H,	--	9937271(+)	`agcccT/Agatca`	2	--	us2k¹		2		WA CSA	4
rs181553511^1,2		--	9937348(+)	`AAATTA/TAAAAA`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for UBL5 (9938568 - 9940797 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for UBL5: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBL5

DNA2.0 Custom Variant and Variant Library Synthesis for UBL5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

UBL5 for disorders           About GeneDecksing

OMIM gene information: 606849    OMIM disorders: --

8 diseases for UBL5:    About MalaCards

obesity autism spectrum disorder amyotrophic lateral sclerosis lateral sclerosis

hepatocellular carcinoma schizophrenia carcinoma malaria

Genetic Association Database (GAD): UBL5
Human Genome Epidemiology (HuGE) Navigator: UBL5 (18 documents)

Export disorders for UBL5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for UBL5 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with UBL5)

Utopia: connect your pdf to the dynamic
world of online information

Structural analysis of UBL5, a novel ubiquitin-like modifier. (PubMed id 12824502)^{1, 2, 9} McNally T....Reilly R.M. (2003)
Isolation of a ubiquitin-like (UBL5) gene from a screen identifying highly expressed and conserved iris genes. (PubMed id 11161819)^{1, 2, 9} Friedman J.S.... Walter M.A. (2001)
Genetic variation in BEACON influences quantitative variation in metabolic syndrome-related phenotypes. (PubMed id 15331561)^{1, 4} Jowett J.B....Blangero J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Beacon interacts with cdc2/cdc28-like kinases. (PubMed id 12705895)^{1, 2} Kantham L.... Collier G. (2003)
Beacon-like/ubiquitin-5-like immunoreactivity is highly expressed in human hypothalamus and increased in haloperidol-treated schizophrenics and a rat model of schizophrenia. (PubMed id 18191906)^{1, 9} Bernstein H.G....Bogerts B. (2008)
Identification of sequence variants in the UBL5 (ubiquitin-like 5 or BEACON) gene in obese children by PCR-SSCP: no evidence for association with obesity. (PubMed id 19189687)^{1, 9} Sentinelli F....Baroni M.G. (2008)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 59286	HGNC: 13736	AceView: UBL5	Ensembl:ENSG00000198258	euGenes: HUgn59286
ECgene: UBL5	H-InvDB: UBL5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for UBL5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for UBL5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for UBL5 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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