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Aliases for UBL4B Gene

Aliases for UBL4B Gene

  • Ubiquitin-Like 4B 2 3

External Ids for UBL4B Gene

Previous GeneCards Identifiers for UBL4B Gene

  • GC01P110368
  • GC01P110456
  • GC01P110655
  • GC01P108524

Summaries for UBL4B Gene

GeneCards Summary for UBL4B Gene

UBL4B (Ubiquitin-Like 4B) is a Protein Coding gene. An important paralog of this gene is UBL4A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBL4B Gene

Genomics for UBL4B Gene

Regulatory Elements for UBL4B Gene

Genomic Location for UBL4B Gene

Start:
110,112,440 bp from pter
End:
110,113,947 bp from pter
Size:
1,508 bases
Orientation:
Plus strand

Genomic View for UBL4B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBL4B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBL4B Gene

Proteins for UBL4B Gene

  • Protein details for UBL4B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7F7-UBL4B_HUMAN
    Recommended name:
    Ubiquitin-like protein 4B
    Protein Accession:
    Q8N7F7
    Secondary Accessions:

    Protein attributes for UBL4B Gene

    Size:
    174 amino acids
    Molecular mass:
    19909 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • May have arisen from retrotransposition of the X-linked UBL4A gene during mammalian evolution

neXtProt entry for UBL4B Gene

Proteomics data for UBL4B Gene at MOPED

Post-translational modifications for UBL4B Gene

No Post-translational modifications

Other Protein References for UBL4B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBL4B Gene

Domains for UBL4B Gene

Protein Domains for UBL4B Gene

Suggested Antigen Peptide Sequences for UBL4B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N7F7

UniProtKB/Swiss-Prot:

UBL4B_HUMAN :
  • Q8N7F7
Domain:
  • Contains 1 ubiquitin-like domain.
genes like me logo Genes that share domains with UBL4B: view

No data available for Gene Families for UBL4B Gene

Function for UBL4B Gene

Gene Ontology (GO) - Molecular Function for UBL4B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with UBL4B: view

Phenotypes for UBL4B Gene

GenomeRNAi human phenotypes for UBL4B:
genes like me logo Genes that share phenotypes with UBL4B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for UBL4B Gene

Localization for UBL4B Gene

Subcellular locations from UniProtKB/Swiss-Prot for UBL4B Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UBL4B Gene COMPARTMENTS Subcellular localization image for UBL4B gene
Compartment Confidence
cytosol 2
mitochondrion 2
cytoskeleton 1
extracellular 1

Gene Ontology (GO) - Cellular Components for UBL4B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with UBL4B: view

Pathways for UBL4B Gene

SuperPathways for UBL4B Gene

No Data Available

Gene Ontology (GO) - Biological Process for UBL4B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with UBL4B: view

No data available for Pathways by source for UBL4B Gene

Transcripts for UBL4B Gene

mRNA/cDNA for UBL4B Gene

(13) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for UBL4B Gene

Ubiquitin-like 4B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for UBL4B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBL4B Gene

No ASD Table

Relevant External Links for UBL4B Gene

GeneLoc Exon Structure for
UBL4B
ECgene alternative splicing isoforms for
UBL4B

Expression for UBL4B Gene

mRNA expression in normal human tissues for UBL4B Gene

mRNA differential expression in normal tissues according to GTEx for UBL4B Gene

This gene is overexpressed in Testis (47.8).

SOURCE GeneReport for Unigene cluster for UBL4B Gene Hs.374027

genes like me logo Genes that share expressions with UBL4B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for UBL4B Gene

Orthologs for UBL4B Gene

This gene was present in the common ancestor of animals.

Orthologs for UBL4B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBL4B 35
  • 99.03 (n)
  • 98.26 (a)
UBL4B 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UBL4B 35
  • 80.08 (n)
  • 71.95 (a)
UBL4B 36
  • 68 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UBL4B 35
  • 81.59 (n)
  • 79.65 (a)
UBL4B 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ubl4b 35
  • 75.11 (n)
  • 72.73 (a)
Ubl4b 16
Ubl4b 36
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia UBL4B 36
  • 42 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 42 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii UBL4A 36
  • 38 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG7215 36
  • 22 (a)
OneToMany
Species with no ortholog for UBL4B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UBL4B Gene

ENSEMBL:
Gene Tree for UBL4B (if available)
TreeFam:
Gene Tree for UBL4B (if available)

Paralogs for UBL4B Gene

Paralogs for UBL4B Gene

Selected SIMAP similar genes for UBL4B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with UBL4B: view

Variants for UBL4B Gene

Sequence variations from dbSNP and Humsavar for UBL4B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs665706 -- 110,111,081(+) TGAGC(C/T)GGGGG upstream-variant-2KB
rs705285 -- 110,110,912(+) CAGTT(C/T)TAAAA upstream-variant-2KB
rs705286 -- 110,113,607(+) CAGCA(A/G)AGGTG utr-variant-3-prime
rs4284264 -- 110,111,717(+) cactc(C/T)agcct upstream-variant-2KB
rs4641310 -- 110,111,876(+) TGCAC(A/G)TTTTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for UBL4B Gene

Variant ID Type Subtype PubMed ID
nsv2343 CNV Insertion 18451855
nsv509424 CNV Insertion 20534489

Relevant External Links for UBL4B Gene

HapMap Linkage Disequilibrium report
UBL4B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBL4B Gene

Disorders for UBL4B Gene

No disorders were found for UBL4B Gene.

No data available for UniProtKB/Swiss-Prot for UBL4B Gene

Publications for UBL4B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Ubl4b, an X-derived retrogene, is specifically expressed in post-meiotic germ cells in mammals. (PMID: 16872915) Yang F. … Wang P.J. (Gene Expr. Patterns 2007) 2 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3

Products for UBL4B Gene

Sources for UBL4B Gene

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