Aliases for UBL3 Gene
Aliases for UBL3 Gene
External Ids for UBL3 Gene
- HGNC: 12504
- Entrez Gene: 5412
- Ensembl: ENSG00000122042
- OMIM: 604711
- UniProtKB: O95164
Previous HGNC Symbols for UBL3 Gene
- PNSC1
Previous GeneCards Identifiers for UBL3 Gene
- GC13M028318
- GC13M024318
- GC13M029268
- GC13M028136
- GC13M029236
- GC13M030338
- GC13M011152
Summaries for UBL3 Gene
GeneCards Summary for UBL3 Gene
UBL3 (Ubiquitin Like 3) is a Protein Coding gene.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBL3 Gene
Genomics for UBL3 Gene
Regulatory Elements for UBL3 Gene
Enhancers for UBL3 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around UBL3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for UBL3 Gene
- Chromosome:
- 13
- Start:
- 29,764,371 bp from pter
- End:
- 29,850,684 bp from pter
- Size:
- 86,314 bases
- Orientation:
- Minus strand
Genomic View for UBL3 Gene
Genes around UBL3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q12.3 by Ensembl
- 13q12-q13 by Entrez Gene
- 13q12-q13 by HGNC
UBL3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for UBL3 Gene
Proteins for UBL3 Gene
-
Protein details for UBL3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95164-UBL3_HUMAN
- Recommended name:
- Ubiquitin-like protein 3
- Protein Accession:
- O95164
- B2R4J1
- Q5RL72
- Q5VZS0
- Q6FIG8
- Q96SG7
Protein attributes for UBL3 Gene
- Size:
- 117 amino acids
- Molecular mass:
- 13157 Da
- Quaternary structure:
- No Data Available
Protein Expression for UBL3 Gene
Post-translational modifications for UBL3 Gene
Other Protein References for UBL3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for UBL3
- Abcam antibodies for UBL3
- GeneTex Cd4 antibody for UBL3
-
Custom Antibody ServicesProSci Antibodies for UBL3
-
Santa Cruz Biotechnology (SCBT) Antibodies for UBL3
Protein Products
-
OriGene Purified Proteins for UBL3
- Search Origene for MassSpec and Protein Over-expression Lysates for UBL3
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- ProSpec Recombinant Proteins for UBL3
- Search GeneTex for Proteins for UBL3
- Abcam proteins for UBL3
Assay Products
No data available for DME Specific Peptides for UBL3 Gene
Domains & Families for UBL3 Gene
Protein Domains for UBL3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for UBL3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O95164- Domain:
-
- Contains 1 ubiquitin-like domain.
No data available for Gene Families for UBL3 Gene
Function for UBL3 Gene
Molecular function for UBL3 Gene
- GENATLAS Biochemistry:
- ubiquitin-like protein 3, Drosophila homolog,highly conserved in man and C elegans
Phenotypes for UBL3 Gene
- GenomeRNAi human phenotypes for UBL3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for UBL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for UBL3 gene
- Search ViGene Biosciences for UBL3
CRISPR Products
-
OriGene CRISPR knockouts for UBL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for UBL3
- GenScript: Design CRISPR guide RNA sequences for UBL3
miRNA for UBL3 Gene
- miRTarBase miRNAs that target UBL3
-
- hsa-mir-215-5p (MIRT024892)
- hsa-mir-192-5p (MIRT026728)
- hsa-mir-30a-5p (MIRT028556)
- hsa-mir-26b-5p (MIRT029836)
- hsa-mir-186-5p (MIRT045013)
- hsa-mir-181a-5p (MIRT437654)
- hsa-mir-192-3p (MIRT443168)
- hsa-mir-3915 (MIRT443169)
- hsa-mir-3928-3p (MIRT443170)
- hsa-mir-4502 (MIRT443171)
- hsa-mir-365b-3p (MIRT443172)
- hsa-mir-365a-3p (MIRT443173)
- hsa-mir-5692a (MIRT443174)
- hsa-mir-155-5p (MIRT553121)
- hsa-mir-5700 (MIRT553122)
- hsa-mir-5002-5p (MIRT553123)
- hsa-mir-3591-5p (MIRT683174)
- hsa-mir-374b-3p (MIRT683175)
- hsa-mir-4473 (MIRT683176)
- hsa-mir-4671-3p (MIRT683177)
- hsa-mir-6847-3p (MIRT683178)
- hsa-mir-512-3p (MIRT683179)
- hsa-mir-6854-5p (MIRT683180)
- hsa-mir-520f-3p (MIRT683181)
- hsa-mir-302c-3p (MIRT683182)
- hsa-mir-19b-3p (MIRT683183)
- hsa-mir-19a-3p (MIRT683184)
- hsa-mir-5587-5p (MIRT697829)
- hsa-mir-4693-5p (MIRT697830)
- hsa-mir-3143 (MIRT697831)
- hsa-mir-194-5p (MIRT697832)
- hsa-mir-6505-3p (MIRT697833)
- hsa-mir-617 (MIRT697834)
- hsa-mir-4744 (MIRT697835)
- hsa-mir-1183 (MIRT697836)
- hsa-mir-543 (MIRT697837)
- hsa-mir-5582-3p (MIRT697838)
- hsa-mir-548f-3p (MIRT697839)
- hsa-mir-548e-3p (MIRT697840)
- hsa-mir-548az-3p (MIRT697841)
- hsa-mir-548ar-3p (MIRT697842)
- hsa-mir-548a-3p (MIRT697843)
miRNA Products
- Search ViGene Biosciences for UBL3
Clone Products
- OriGene clones in human for UBL3
- OriGene ORF clones in human,mouse,rat for UBL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for UBL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for UBL3
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for UBL3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for UBL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for UBL3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UBL3 Gene
Localization for UBL3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for UBL3 Gene
- Cell membrane; Lipid-anchor.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 3 |
| plasma membrane | 3 |
| cytoskeleton | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005622 | intracellular | IDA | -- |
| GO:0070062 | extracellular exosome | IDA | 19056867 |
Pathways & Interactions for UBL3 Gene
More details on SuperPathways for UBL3
No Data Available
Interacting Proteins for UBL3 Gene
No data available for Pathways by source and SIGNOR curated interactions for UBL3 Gene
Transcripts for UBL3 Gene
mRNA/cDNA for UBL3 Gene
- (2) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (307) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for UBL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for UBL3
- GenScript: Design CRISPR guide RNA sequences for UBL3
miRNA Products
- Search ViGene Biosciences for UBL3
Clone Products
- OriGene clones in human for UBL3
- OriGene ORF clones in human,mouse,rat for UBL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for UBL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for UBL3
Flow Cytometry Products
Expression for UBL3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Cervix (43.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for UBL3 Gene
SOURCE GeneReport for Unigene cluster for UBL3 Gene Hs.145575
mRNA Expression by UniProt/SwissProt for UBL3 Gene
O95164-UBL3_HUMAN
Tissue specificity:
Ubiquitous.
Primer Products
-
OriGene qPCR primer pairs and template standards for UBL3
-
OriGene qPCR primer pairs for UBL3
No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for UBL3 Gene
Orthologs for UBL3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | UBL3 35 |
|
||
| UBL3 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | UBL3 35 |
|
||
| UBL3 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Ubl3 35 |
|
||
| Ubl3 16 |
|
||||
| Ubl3 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | UBL3 35 |
|
||
| UBL3 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Ubl3 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | UBL3 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | UBL3 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | UBL3 35 |
|
||
| UBL3 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | UBL3 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.5748 35 |
|
||
| ubl3 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.21417 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ubl3a 35 |
|
||
| ubl3a 36 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | UBL3 37 |
|
|
|
| UBL3 35 |
|
||||
| UBL3 36 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP013294 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | C46F11.6 35 |
|
||
| C46F11.6 36 |
|
OneToOne |
- Species with no ortholog for UBL3:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for UBL3 Gene
No data available for Paralogs for UBL3 Gene
Variants for UBL3 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs166760 | -- | 29,846,101(-) | ACTTA(C/T)GTTAA | intron-variant | |
| rs175875 | -- | 29,847,845(+) | GTATG(A/G)AGGAA | intron-variant | |
| rs278031 | -- | 29,845,421(-) | TTTCT(A/C)TTCCT | intron-variant | |
| rs278032 | -- | 29,844,800(-) | ATGGT(A/G)CTAAT | intron-variant | |
| rs278033 | -- | 29,842,825(+) | AGCCC(C/T)CCTAA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv899961 | CNV | Gain | 21882294 |
| esv1537429 | CNV | Deletion | 17803354 |
Residual Variation Intolerance Score:
64.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.12;
2.76% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for UBL3 Gene
Disorders for UBL3 Gene
Relevant External Links for UBL3
No disorders were found for UBL3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBL3 Gene
Publications for UBL3 Gene
- Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene. (PMID: 10375635) Chadwick B.P. … Frischauf A.-M. (Gene 1999) 2 3 4 67
- Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
- A genome-wide association study for reading and language abilities in two population cohorts. (PMID: 23738518) Luciano M. … Bates T.C. (Genes Brain Behav. 2013) 3
- Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
Products for UBL3 Gene
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- OriGene qPCR primer pairs for UBL3
- OriGene qPCR primer pairs and template standards for UBL3
- OriGene CRISPR knockouts for UBL3
- OriGene clones in human for UBL3
- OriGene ORF clones in human,mouse,rat for UBL3
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- Novus Biologicals proteins and lysates for UBL3
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- Abcam antibodies for UBL3
- Abcam proteins for UBL3
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- ViGene Biosciences ready-to-package AAV shRNAs for UBL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for UBL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for UBL3 gene
- Search ViGene Biosciences for UBL3
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- Santa Cruz Biotechnology (SCBT) Antibodies for UBL3
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- Santa Cruz Biotechnology (SCBT) CRISPR for UBL3
- Custom Antibody ServicesProSci Antibodies for UBL3
Sources for UBL3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon