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Aliases for UBL3 Gene

Aliases for UBL3 Gene

  • Ubiquitin-Like 3 2 3
  • Membrane-Anchored Ubiquitin-Fold Protein 3 4
  • Protein HCG-1 3 4
  • HsMUB 3 4
  • PNSC1 3 4
  • MUB 3 4
  • Ubiquitin-Like Protein 3 3
  • HCG-1 3

External Ids for UBL3 Gene

Previous HGNC Symbols for UBL3 Gene

  • PNSC1

Previous GeneCards Identifiers for UBL3 Gene

  • GC13M028318
  • GC13M024318
  • GC13M029268
  • GC13M028136
  • GC13M029236
  • GC13M030338
  • GC13M011152

Summaries for UBL3 Gene

GeneCards Summary for UBL3 Gene

UBL3 (Ubiquitin-Like 3) is a Protein Coding gene.

Gene Wiki entry for UBL3 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBL3 Gene

Genomics for UBL3 Gene

Regulatory Elements for UBL3 Gene

Genomic Location for UBL3 Gene

Start:
29,764,371 bp from pter
End:
29,850,684 bp from pter
Size:
86,314 bases
Orientation:
Minus strand

Genomic View for UBL3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBL3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBL3 Gene

Proteins for UBL3 Gene

  • Protein details for UBL3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95164-UBL3_HUMAN
    Recommended name:
    Ubiquitin-like protein 3
    Protein Accession:
    O95164
    Secondary Accessions:
    • B2R4J1
    • Q5RL72
    • Q5VZS0
    • Q6FIG8
    • Q96SG7

    Protein attributes for UBL3 Gene

    Size:
    117 amino acids
    Molecular mass:
    13157 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for UBL3 Gene

neXtProt entry for UBL3 Gene

Proteomics data for UBL3 Gene at MOPED

Post-translational modifications for UBL3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UBL3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBL3 Gene

Domains for UBL3 Gene

Protein Domains for UBL3 Gene

Suggested Antigen Peptide Sequences for UBL3 Gene

Graphical View of Domain Structure for InterPro Entry

O95164

UniProtKB/Swiss-Prot:

UBL3_HUMAN :
  • O95164
Domain:
  • Contains 1 ubiquitin-like domain.
genes like me logo Genes that share domains with UBL3: view

No data available for Gene Families for UBL3 Gene

Function for UBL3 Gene

Molecular function for UBL3 Gene

GENATLAS Biochemistry: ubiquitin-like protein 3, Drosophila homolog,highly conserved in man and C elegans

Gene Ontology (GO) - Molecular Function for UBL3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with UBL3: view

Phenotypes for UBL3 Gene

GenomeRNAi human phenotypes for UBL3:
genes like me logo Genes that share phenotypes with UBL3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for UBL3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for UBL3 Gene

Localization for UBL3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UBL3 Gene

Cell membrane; Lipid-anchor.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for UBL3 Gene COMPARTMENTS Subcellular localization image for UBL3 gene
Compartment Confidence
plasma membrane 5
cytosol 3
nucleus 2
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for UBL3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
GO:0005886 plasma membrane IEA --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with UBL3: view

Pathways for UBL3 Gene

SuperPathways for UBL3 Gene

No Data Available

Interacting Proteins for UBL3 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000370055%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000370055 for UBL3 Gene via STRING

Gene Ontology (GO) - Biological Process for UBL3 Gene

None

No data available for Pathways by source for UBL3 Gene

Transcripts for UBL3 Gene

mRNA/cDNA for UBL3 Gene

(307) Selected AceView cDNA sequences:
(2) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for UBL3 Gene

Ubiquitin-like 3:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for UBL3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBL3 Gene

No ASD Table

Relevant External Links for UBL3 Gene

GeneLoc Exon Structure for
UBL3
ECgene alternative splicing isoforms for
UBL3

Expression for UBL3 Gene

mRNA expression in normal human tissues for UBL3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for UBL3 Gene

SOURCE GeneReport for Unigene cluster for UBL3 Gene Hs.145575

mRNA Expression by UniProt/SwissProt for UBL3 Gene

O95164-UBL3_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expressions with UBL3: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for UBL3 Gene

Orthologs for UBL3 Gene

This gene was present in the common ancestor of animals.

Orthologs for UBL3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBL3 35
  • 100 (n)
  • 100 (a)
UBL3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UBL3 35
  • 93.16 (n)
  • 100 (a)
UBL3 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UBL3 35
  • 97.72 (n)
  • 100 (a)
UBL3 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ubl3 35
  • 88.32 (n)
  • 99.15 (a)
Ubl3 16
Ubl3 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia UBL3 36
  • 99 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UBL3 36
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ubl3 35
  • 87.46 (n)
  • 99.15 (a)
chicken
(Gallus gallus)
Aves UBL3 35
  • 86.89 (n)
  • 98.29 (a)
UBL3 36
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UBL3 36
  • 97 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.21417 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.5748 35
ubl3 35
  • 84.62 (n)
  • 96.58 (a)
zebrafish
(Danio rerio)
Actinopterygii ubl3a 35
  • 79.2 (n)
  • 93.16 (a)
ubl3a 36
  • 93 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP013294 35
  • 64.01 (n)
  • 73.45 (a)
fruit fly
(Drosophila melanogaster)
Insecta UBL3 35
  • 63.74 (n)
  • 71.05 (a)
UBL3 36
  • 24 (a)
OneToOne
UBL3 37
  • 71 (a)
worm
(Caenorhabditis elegans)
Secernentea C46F11.6 35
  • 55.15 (n)
  • 56.36 (a)
C46F11.6 36
  • 51 (a)
OneToOne
Species with no ortholog for UBL3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UBL3 Gene

ENSEMBL:
Gene Tree for UBL3 (if available)
TreeFam:
Gene Tree for UBL3 (if available)

Paralogs for UBL3 Gene

No data available for Paralogs for UBL3 Gene

Variants for UBL3 Gene

Sequence variations from dbSNP and Humsavar for UBL3 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs166760 -- 29,846,101(-) ACTTA(C/T)GTTAA intron-variant
rs175875 -- 29,847,845(+) GTATG(A/G)AGGAA intron-variant
rs278031 -- 29,845,421(-) TTTCT(A/C)TTCCT intron-variant
rs278032 -- 29,844,800(-) ATGGT(A/G)CTAAT intron-variant
rs278033 -- 29,842,825(+) AGCCC(C/T)CCTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UBL3 Gene

Variant ID Type Subtype PubMed ID
nsv899961 CNV Gain 21882294
esv1537429 CNV Deletion 17803354

Relevant External Links for UBL3 Gene

HapMap Linkage Disequilibrium report
UBL3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBL3 Gene

Disorders for UBL3 Gene

Relevant External Links for UBL3

Genetic Association Database (GAD)
UBL3
Human Genome Epidemiology (HuGE) Navigator
UBL3
genes like me logo Genes that share disorders with UBL3: view

No data available for UniProtKB/Swiss-Prot for UBL3 Gene

Publications for UBL3 Gene

  1. Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene. (PMID: 10375635) Chadwick B.P. … Frischauf A.-M. (Gene 1999) 2 3 4
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for UBL3 Gene

Sources for UBL3 Gene

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