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UBL3 Gene

protein-coding GIFtS: 52
GCID: GC13M030338

Ubiquitin-Like 3

(Previous symbol: PNSC1)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Ubiquitin-Like 3¹ ²		HCG-1²
PNSC1¹ ² ³		hsMUB²
Membrane-Anchored Ubiquitin-Fold Protein² ³		Ubiquitin-Like Protein 3²
Protein HCG-1² ³		HsMUB³
MUB² ³

External Ids:	HGNC: 12504¹	Entrez Gene: 5412²	Ensembl: ENSG00000122042⁷	OMIM: 604711⁵	UniProtKB: O95164³

Export aliases for UBL3 gene to outside databases

Previous GC identifers: GC13M028318 GC13M024318 GC13M029268 GC13M028136 GC13M029236 GC13M011152

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UBL3 Gene:

UBL3 (ubiquitin-like 3) is a protein-coding gene. Diseases associated with UBL3 include biliary atresia, and alcohol abuse.

Gene Wiki entry for UBL3 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000013.11 NC_018924.2 NT_024524.15

Regulatory elements:

Regulatory transcription factor binding sites in the UBL3 gene promoter:
HOXA3 AML1a MyoD AP-4 IRF-1 CUTL1 AP-2gamma LCR-F1 Egr-4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: UBL3 promoter sequence

Search Chromatin IP Primers for UBL3

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBL3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12-q13 Ensembl cytogenetic band: 13q12.3 HGNC cytogenetic band: 13q12-q13

UBL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBL3 gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13M030338: view genomic region (about GC identifiers)

Start:	30,338,508 bp from pter	End:	30,424,821 bp from pter
Size:	86,314 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: UBL3_HUMAN, O95164 (See protein sequence)

Recommended Name: Ubiquitin-like protein 3 precursor

Size: 117 amino acids; 13157 Da

1 PDB 3D structure from and Proteopedia for UBL3:

2GOW (3D)

Secondary accessions: B2R4J1 Q5RL72 Q5VZS0 Q6FIG8 Q96SG7

Explore the universe of human proteins at neXtProt for UBL3: NX_O95164

Explore proteomics data for UBL3 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See UBL3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_009037.1

ENSEMBL proteins:

ENSP00000370055

UBL3 Human Recombinant Protein Products:

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UBL3 Antibody Products:

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UBL3 Assay Products:

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	Cloud-Clone Corp. ELISAs for UBL3 Cloud-Clone Corp. CLIAs for UBL3

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:

IPR000626 Ubiquitin_dom

IPR017000 M-anchored_Ub-fold_HCG-1

Graphical View of Domain Structure for InterPro Entry O95164

ProtoNet protein and cluster: O95164

1 Blocks protein domain: IPB000626 Ubiquitin domain

UniProtKB/Swiss-Prot: UBL3_HUMAN, O95164

Similarity: Contains 1 ubiquitin-like domain

UBL3 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

Genatlas biochemistry entry for UBL3:

ubiquitin-like protein 3, Drosophila homolog,highly conserved in man and C elegans

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

UBL3 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for UBL3:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UBL3

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for UBL3

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UBL3

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UBL3

miRNA Products:		miRTarBase miRNAs that target UBL3: hsa-mir-215-5p (MIRT024892), hsa-mir-26b-5p (MIRT029836), hsa-mir-30a-5p (MIRT028556), hsa-mir-186-5p (MIRT045013), hsa-mir-192-5p (MIRT026728)

		Block miRNA regulation of human, mouse, rat UBL3 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate UBL3 (see all 84):
		hsa-miR-3678-3p hsa-miR-579 hsa-miR-607 hsa-miR-520f hsa-miR-300 hsa-miR-4272 hsa-miR-15a hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: UBL3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for UBL3
		Predesigned siRNA for gene silencing in human, mouse, rat UBL3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for UBL3

Clone Products:		OriGene clones in human, mouse for UBL3 (see all 7) OriGene ORF clones in mouse, rat for UBL3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		Sino Biological Human cDNA Clone for UBL3
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBL3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for UBL3
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBL3

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

UBL3_HUMAN, O95164: Cell membrane; Lipid-anchor (By similarity)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
plasma membrane	5
cytosol	3
nucleus	2
endoplasmic reticulum	1
extracellular	1
mitochondrion	1
peroxisome	1

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Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IDA	--
GO:0005886	plasma membrane	IEA	--
GO:0070062	extracellular vesicular exosome	IDA	19056867

UBL3 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for UBL3
Interactions:

Search GeneGlobe Interaction Network for UBL3

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for UBL3 (ENSP00000370055⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for UBL3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for UBL3 gene:

NM_007106.3

Unigene Cluster for UBL3:

Ubiquitin-like 3

Hs.145575 [show with all ESTs]

Unigene Representative Sequence: NM_007106

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000380680(uc001usp.3)

miRNA Products:		Block miRNA regulation of human, mouse, rat UBL3 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate UBL3 (see all 84):
		hsa-miR-3678-3p hsa-miR-579 hsa-miR-607 hsa-miR-520f hsa-miR-300 hsa-miR-4272 hsa-miR-15a hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: UBL3 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for UBL3
		Predesigned siRNA for gene silencing in human, mouse, rat UBL3

Clone Products:		OriGene clones in human, mouse for UBL3 (see all 7) OriGene ORF clones in mouse, rat for UBL3 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: UBL3 (NM_007106)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for UBL3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBL3

Primer Products:		OriGene qPCR primer pairs and template standards for UBL3 OriGene qSTAR qPCR primer pairs in human, mouse for UBL3
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat UBL3
		QuantiTect SYBR Green Assays in human, mouse, rat UBL3
		QuantiFast Probe-based Assays in human, mouse, rat UBL3

Additional mRNA sequence:

AF044221.1 AK056580.1 AK307361.1 AK309253.1 AK311846.1 AL080177.1 BC044582.1 BC059385.1

CR533458.1

15 DOTS entries:

DT.445834 DT.100681183 DT.95352397 DT.100783450 DT.91769174 DT.120777901 DT.99951603 DT.99949567

DT.95356482 DT.120777923 DT.120778009 DT.91769155 DT.95352395 DT.91739663 DT.91920372

Selected AceView cDNA sequences (see all 307):

AA490497 AI378191 CA312862 BQ024888 BE855788 AI307685 BM129174 AA508749

BM128734 Z40758 BP367998 AI953783 AA970077 AI568179 BM980660 CA389150

BQ215497 BM782563 BM974929 BM667282 AI252639 N20041 R44787 AK056580

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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UBL3 expression in normal human tissues (normalized intensities) UBL3 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GAAAAATACA

About this image

UBL3 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 3) fully expand


Brain (Nervous System)
Cerebral Cortex

Placenta (Extraembryonic Tissues)

Stomach (Gastrointestinal Tract)

UBL3 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

UBL3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.145575

UniProtKB/Swiss-Prot: UBL3_HUMAN, O95164

Tissue specificity: Ubiquitous

Custom PCR Arrays for UBL3

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		Pre-validated RT² qPCR Primer Assay in human, mouse, rat UBL3
		QuantiTect SYBR Green Assays in human, mouse, rat UBL3
		QuantiFast Probe-based Assays in human, mouse, rat UBL3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBL3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for UBL3 gene from Selected species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ubl3^{1 , 5}	ubiquitin-like 3^{1, 5}	88.32(n)¹ 99.15(a)¹		5 (88.66 cM)⁵ 24109¹ NM_011908.2¹ NP_036038.1¹ 148504631⁵
chicken (Gallus gallus)	Aves	UBL3¹	ubiquitin-like 3	86.89(n) 98.29(a)		418921 NM_001012829.1 NP_001012847.1
lizard (Anolis carolinensis)	Reptilia	UBL3⁶	ubiquitin-like 3	97(a)	1 ↔ 1	3(184824229-184870588)
African clawed frog (Xenopus laevis)	Amphibia	Xl.21417²	Xenopus laevis, clone IMAGE5570630, mRNA, partial cds	79.15(n)		BC044683.1
zebrafish (Danio rerio)	Actinopterygii	ubl3a¹	ubiquitin-like 3a	79.2(n) 93.16(a)		324710 NM_212686.1 NP_997851.1
fruit fly (Drosophila melanogaster)	Insecta	UBL3^{1 , 3}	UBL3¹	71(a)³ 63.74(n)¹ 71.05(a)¹		1 13F13³ 32541¹ NM_001169292.1¹ NP_001162763.1¹
worm (Caenorhabditis elegans)	Secernentea	C46F11.6¹	C46F11.6	55.15(n) 56.36(a)		259497 NM_001026051.4 NP_001021222.1

ENSEMBL Gene Tree for UBL3 (if available)
TreeFam Gene Tree for UBL3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76675026^1,2	F	--	30338152(+)	`CACAAA/TAACTG`	1	--	int¹		1		WA	118
rs145652863^1,2		--	30338267(+)	`CTCCAC/TTTGGC`	1	--	int¹		0	--	--	--	--
rs187893333^1,2		--	30338276(+)	`GCTAAC/TAAGTG`	1	--	int¹		0	--	--	--	--
rs192524614^1,2		--	30338323(+)	`ATGCTC/TGAAAA`	1	--	int¹		0	--	--	--	--
rs183344012^1,2		--	30338344(+)	`AAAAAC/TGGTAT`	1	--	int¹		0	--	--	--	--
rs9314976^1,2	C,F,H	--	30338359(+)	`GCATAT/CTAAAT`	1	--	int¹		30		NS NA EA WA	3000
rs117847911^1,2	F	--	30338684(+)	`TTAACG/ATGAAT`	1	--	ut3¹		2		NA EA	240
rs148758223^1,2		--	30338813(+)	`CAGAAC/TACTTA`	1	--	ut3¹		0	--	--	--	--
rs187257204^1,2		--	30338832(+)	`CAGGAC/GAATTT`	1	--	ut3¹		0	--	--	--	--
rs111654999^1,2	C	--	30338938(+)	`TTTAGA/GTAAGT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for UBL3 (30338508 - 30424821 bp)

Structural Variations
Database of Genomic Variants (DGV) 2 variations for UBL3: About this table

Variant ID	Type	Subtype	PubMed ID
esv1537429	CNV	Deletion	17803354
nsv899961	CNV	Gain	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing UBL3

DNA2.0 Custom Variant and Variant Library Synthesis for UBL3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 604711 OMIM disorders: --

2 diseases for UBL3: About MalaCards

biliary atresia alcohol abuse

UBL3 for disorders About GeneDecksing

Genetic Association Database (GAD): UBL3
Human Genome Epidemiology (HuGE) Navigator: UBL3 (1 document)

Export disorders for UBL3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for UBL3 gene, integrated from 10 sources (see all 20):
(articles sorted by number of sources associating them with UBL3)

Utopia: connect your pdf to the dynamic
world of online information

Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene. (PubMed id 10375635)^{1, 2, 3} Chadwick B.P.... Frischauf A.-M. (Gene 1999)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (Mol. Med. 2010)
Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. (PubMed id 20460270)^{1, 4} Garcia-BarcelA^ M.M....Tam P.K. (Hum. Mol. Genet. 2010)
MUBS: a family of ubiquitin-fold proteins that are plasma membrane- anchored by prenylation. (PubMed id 16831869)^{1, 2} Downes B.P.... Vierstra R.D. (J. Biol. Chem. 2006)
The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)^{1, 2} Dunham A.... Ross M.T. (Nature 2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (Genome Res. 2001)
A genome-wide association study for reading and language abilities in two population cohorts. (PubMed id 23738518)¹ Luciano M....Bates T.C. (Genes Brain Behav. 2013)
Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 5412	HGNC: 12504	AceView: UBL3	Ensembl:ENSG00000122042	euGenes: HUgn5412
ECgene: UBL3	H-InvDB: UBL3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for UBL3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for UBL3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for UBL3 gene:
Search GeneIP for patents involving UBL3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for UBL3
	OriGene qPCR primer pairs and template standards for UBL3		OriGene Protein Over-expression Lysate for UBL3
	OriGene MassSpec something-or-other for UBL3		OriGene clones in human, mouse for UBL3
	OriGene qSTAR qPCR primer pairs in human, mouse for UBL3		OriGene Purified Protein for UBL3
	OriGene ORF clones in mouse, rat for UBL3		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for UBL3		OriGene Custom Protein Services for UBL3

	Block miRNA regulation of human, mouse, rat UBL3 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing UBL3
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBL3		Predesigned siRNA for gene silencing in human, mouse, rat UBL3
	QuantiFast Probe-based Assays in human, mouse, rat UBL3		QuantiTect SYBR Green Assays in human, mouse, rat UBL3
	Custom PCR Arrays for UBL3		Search Chromatin IP Primers for UBL3
	Pre-validated RT² qPCR Primer Assay in human, mouse, rat UBL3		Search GeneGlobe Interaction Network for UBL3
	Regulatory tfbs in UBL3 promoter

	GenScript Custom Purified and Recombinant Proteins Services for UBL3		GenScript cDNA clones with any tag delivered in your preferred vector for UBL3
	GenScript Custom Assay Services for UBL3		GenScript Custom overexpressing Cell Line Services for UBL3
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

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Search Tocris compounds for UBL3

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	Novus Tissue Slides
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Recombinant Protein for UBL3

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	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBL3

	SwitchGear 3'UTR luciferase reporter plasmids for UBL3
	SwitchGear Promoter luciferase reporter plasmids for UBL3

Search ThermoFisher Antibodies for UBL3

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBL3

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UBL3
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for UBL3

LSBio Antibodies in human, mouse, rat for UBL3

Customized transgenic rodents for:

	Humanization
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	Off-target effect monitoring
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	Tissue-specific gene expresssion
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes UBL3 gene at Home site.

Version: 3.12.136 22 July 2014
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UBL3 Gene

Ubiquitin-Like 3

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