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UBE4A Gene

protein-coding GIFtS: 60

GC11P117735

ubiquitination factor E4A (UFD2 homolog, yeast)
(Previous name: ubiquitination factor E4A (homologous to yeast UFD2) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
E4 ^¹, ², ⁵
KIAA0126 ^¹, ², ³
MGC133315 ^²
UBOX2 ^¹, ²
UFD2 ^¹, ², ⁵

Descriptions
homologous to yeast UFD2 ^²
ubiquitin conjugation factor E4 A ^²
ubiquitination factor E4A ^²
ubiquitination factor E4A (UFD2 homolog, yeast) ^²
ubiquitination factor E4A (homologous to yeast UFD2) ^¹, ²

External Ids
HGNC: 12499¹
Entrez Gene: 9354²
UniProtKB: Q14139³
Ensembl: ENSG00000110344⁷

Search outside databases for aliases for UBE4A gene

Previous GC identifers: GC11P120587 GC11P119742 GC11P118264 GC11P117767

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for UBE4A:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting

abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes

of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and

ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which

is involved in multiubiquitin chain assembly. [provided by RefSeq]

UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139

Function: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain

assembly in conjunction with E1, E2, and E3 (By similarity)

Gene Wiki entry for UBE4A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the UBE4A gene

Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3

UBE4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P117735: (about GC identifiers)

Start:	117,735,512 bp from pter
End:	117,775,136 bp from pter
Size:	39,625 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033899.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139 (See protein sequence)

Recommended Name: Ubiquitin conjugation factor E4 A

Size: 1066 amino acids; 122561 Da

Sequence caution: Sequence=AAH52643.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence.

Potential poly-A sequence; Sequence=AAH62695.1; Type=Miscellaneous discrepancy; Note=Contaminating

sequence. Potential poly-A sequence;

PDB structures from and Proteopedia :

1WGM (3D)

Secondary accessions: Q2M1H0 Q6P5T4 Q7Z639

Alternative splicing: 2 isoforms: Q14139-1 Q14139-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004779.2

ENSEMBL proteins:

ENSP00000252108

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Ube4a)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000151	ubiquitin ligase complex	TAS	10089879
GO:0005737	cytoplasm	IEA	--

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Antibodies for UBE4A:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for UBE4A
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Ube4a), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (UBE4A)
	Novus Biologicals Antibody for UBE4A

Assays for UBE4A:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q14139

ProtoNet protein and cluster: Q14139

1 Blocks protein family: IPB003613 Zn-finger

UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139

Similarity: Belongs to the ubiquitin conjugation factor E4 family

Similarity: Contains 1 U-box domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE4A)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE4A)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004788

Applied Biosystems Silencer® siRNAs for UBE4A

Sigma-Aldrich siRNA and siRNA Panels for UBE4A

Sigma-Aldrich shRNA Panels and shRNA for UBE4A

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004788
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004788
untagged cDNA clone in CMV expression vector: NM_004788

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004788

UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139

Function: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain

assembly in conjunction with E1, E2, and E3 (By similarity)

Genatlas biochemistry entry for UBE4A:

ubiquitination factor E4A,homologous to yeast UFD2,expressed in brain,required for multiubiquitin

chain assembly,in association with E1,E2,E3,related to Drosophila NOSA

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	17353931
GO:0034450	ubiquitin-ubiquitin ligase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for UBE4A (Your Favorite Gene powered by Ingenuity)

Protein Ubiquitination Pathway

GeneDecks UBE4A for the pathways selected above

About GeneDecksing

5/33 Interacting proteins for UBE4A (ENSP00000252108³ Q14139¹) via UniProtKB, MINT, and/or STRING (see all 33 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PTP4A3	O75365¹	EBI-1048119, EBI-1043866
UBE4B	ENSP00000343001³	STRING (score=.918)
BARD1	ENSP00000260947³	STRING (score=.91)
UBE2L3	ENSP00000344259³	STRING (score=.91)
BRCA1	ENSP00000350283³	STRING (score=.909)

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000209	protein polyubiquitination	IEA	--
GO:0006511	ubiquitin-dependent protein catabolic process	TAS	10089879

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for UBE4A

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE4A)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE4A)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004788

Sigma-Aldrich siRNA and siRNA Panels for UBE4A

Sigma-Aldrich shRNA Panels and shRNA for UBE4A

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004788

REFSEQ mRNAs for UBE4A gene:

NM_004788.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004788

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004788
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004788
                                 untagged cDNA clone in CMV expression vector: NM_004788

Additional cDNA sequence:

AF087968.1 AK296369.1 AK302328.1 AK307737.1 BC010938.1 BC030973.1 BC039240.1 BC052643.1

BC062695.1 BC111417.1 BC112367.1 D50916.1

17 DOTS entries:

DT.101983809 DT.101966714 DT.95219286 DT.95228417 DT.317845 DT.92439681 DT.40115731 DT.120693753

DT.101965579 DT.92439683 DT.95292093 DT.100744038 DT.100792366 DT.40314850 DT.91685705 DT.100645178

DT.92439680

24/1072 AceView cDNA sequences (see all 1072 ):

BC052643 BM670047 AI709266 CA866089 BX482035 AI076160 AI298063 BM663670

AI752895 AI343302 AA258888 AW328279 BM840231 AI707661 AA885928 AA721413

BX281788 AA862560 AW512408 BP871644 BQ685207 AI342107 W69159 AA936162

highest scoring ESTs for UBE4A:

D50916 AA007377 AA018397 AA018398 AA019500 AA116126 AA116127 AA127334 AA127335 AA195353

Unigene Cluster for UBE4A:

Ubiquitination factor E4A (UFD2 homolog, yeast)

Hs.75275 [show with all ESTs]

Unigene Representative Sequence: NM_004788

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for UBE4A (see all 6 )

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	^	10a	·	10b	·	10c	^	11	^	12	^	13	^	14	^	15	^	16a	·	16b	^	17a	·	17b	^
SP1:							-																				-																								-
SP2:							-												-								-
SP3:
SP4:
SP5:

ExUns:	18	^	19	^	20a	·	20b	^	21
SP1:					-
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for UBE4A

1 Ensembl transcript including schematic representation:

ENST00000252108

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

UBE4A expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for UBE4A

¹ / ² / ³

5 probe-sets matching UBE4A gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36579_at²^{, 3}	U95-A	1	1.00	1.00	0.17	1.43	D50916	1.00	0.90	0.95	1
71836_at²^{, 3}	U95-E	1	0.94	1.00	0.35	0.91	AI343302	0.60	0.83	0.73	1
80158_at²^{, 3}	U95-E	1	0.81	1.00	0.92	0.69	AI524815	0.80	0.88	0.84	1
202038_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004788	0.60	0.83	0.73	1
202038_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.75275
Expression variation in blood from EXPOLDB for UBE4A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for UBE4A gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	UBE4A¹	--	ubiquitination factor E4A (UFD2 homolog, yeast)	95.06(n) 98.59(a)	479418 XM_844988.1 XP_850081.1
chimpanzee (Pan troglodytes)	UBE4A¹	--	ubiquitination factor E4A (UFD2 homolog, yeast)	99.75(n) 99.72(a)	451586 XM_508791.2 XP_508791.2
cow (Bos taurus)	UBE4A¹	--	ubiquitination factor E4A (UFD2 homolog, yeast)	93.45(n) 96.83(a)	517544 XM_867226.2 XP_872319.1
rat (Rattus norvegicus)	Ube4a¹	--	ubiquitination factor E4A	91.59(n) 96.9(a)	315608 NM_207610.1 NP_997493.1
mouse (Mus musculus)	Ube4a^{1, 5}	9⁵	ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)^{1, 5}	92.28(n)¹ 97.28(a)¹	140630¹ NM_145400.2¹ NP_663375.2¹ AC061963⁵ AI390103⁵ (see all 17)

About this table Species with no ortholog for UBE4A

ENSEMBL Gene Tree for UBE4A

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for UBE4A gene

UBE4B²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/129 NCBI SNPs in UBE4A are shown (see all 129 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 79)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs7110197^1,2	A,C,F,H	117733834(+)	`tttcaG/Cttagc`	1	--	ng5¹		4	EU EA WA	420
	rs2276418^1,2	C,F,H,O	117735474(+)	`CGGAGA/TTGAAC`	1	--	ng5¹		24	EA NS NA MN EU WA	3484
	rs2276417^1,2	A,C,F,H	117735433(+)	`CGCCGT/GTCCCC`	1	--	ng5¹		7	MN EA EU WA NS	1708
	rs2276419^1,2	C,F,H	117735569(+)	`TCTGTC/TGTGTC`	1	--	ut5¹ ese³		17	EA NA EU WA	2180
	rs34452332^1,2	C,F	117749088(+)	`TTCCAG/CAAGTC`	1	Q/E	mis¹		5	NA EU EA WA	460
--	rs35865949^1,2	C,F	117734271(+)	`TTTTTT/ATTTTC`	1	--	ng5¹		1	NS	18
--	rs45489394^1,2	F	117734178(+)	`GCATAC/GGGTTT`	1	--	ng5¹		1	NS	30
	rs531396^1,2	H	117735536(-)	`CACTTC/TCGACT`	1	--	ut5¹ ese³		4	EU EA WA	420
--	rs45474998^1,2	F	117734889(+)	`TATGTG/ATATCC`	1	--	ng5¹		1	NS	38
--	rs502514^1,2	A,C,F,H,O	117747205(+)	`cctacC/Tctatg`	1	--	int¹		16	EA NA EU WA	1298

About this table

HapMap Linkage Disequilibrium images for UBE4A (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603753

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/14 PubMed articles for UBE4A gene (see all 14 ):

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{3, 4} Gevaert K.... Vandekerckhove J. (2003)
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. (PubMed id 10089879)^{2, 3} Koegl M....Jentsch S. (1999)
Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)^{3, 4} Nagase T....Nomura N. (1995)
Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissues. (PubMed id 15019985)^{1, 3} Contino G....Novelli G. (2004)
Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. (PubMed id 18069675)^{1, 3} Sakiyama T....Tsubouchi H. (2008)
[Differential expression of USP2, USP14 and UBE4A between ovarian serous cystadenocarcinoma and adjacent normal tissues] (PubMed id 17553343)^{1, 3} Yang Y....Yang H.J. (2007)
Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)³ Ewing R.M....Figeys D. (2007)
Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation. (PubMed id 15611659)³ Spinette S....Rosen A. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9354	HGNC: 12499	AceView: UBE4AandATP5L	Ensembl:ENSG00000110344	euGenes: HUgn9354
ECgene: UBE4A	H-InvDB: UBE4A

(According to HUGE)
About This Section

HUGE: KIAA0126

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for UBE4A
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for UBE4A:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for UBE4A-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for UBE4A		Antibodies for UBE4A
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for UBE4A		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Antibodies for UBE4A

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UBE4A Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for UBE4A

Summaries
for UBE4A

Genomic Location
for UBE4A

Proteins
for UBE4A

Protein Domains/
Families
for UBE4A

Gene Function
for UBE4A

Pathways & Interactions
for UBE4A

Drugs & Compounds
for UBE4A

Transcripts
for UBE4A

Expression
for UBE4A

Orthologs
for UBE4A

Paralogs
for UBE4A

SNPs/Variants
for UBE4A

Disorders & Mutations
for UBE4A

Medical News
for UBE4A

Publications
for UBE4A

Search for UBE4A

Genome Databases showing UBE4A

Other Databases showing UBE4A

Specialized Databases showing UBE4A

Licensable Technologies
for UBE4A

Services
for UBE4A

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

UBE4A Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor UBE4A

Summariesfor UBE4A

Genomic Locationfor UBE4A

Proteinsfor UBE4A

Protein Domains/Familiesfor UBE4A

Gene Functionfor UBE4A

Pathways & Interactionsfor UBE4A

Drugs & Compoundsfor UBE4A

Transcriptsfor UBE4A

Expression for UBE4A

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Disorders & Mutationsfor UBE4A

Medical Newsfor UBE4A

Publicationsfor UBE4A

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Genome Databases showing UBE4A

Other Databases showing UBE4A

Specialized Databases showing UBE4A

Licensable Technologiesfor UBE4A

Servicesfor UBE4A

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for UBE4A

Summaries
for UBE4A

Genomic Location
for UBE4A

Proteins
for UBE4A

Protein Domains/
Families
for UBE4A

Gene Function
for UBE4A

Pathways & Interactions
for UBE4A

Drugs & Compounds
for UBE4A

Transcripts
for UBE4A

Expression
for UBE4A

Orthologs
for UBE4A

Paralogs
for UBE4A

SNPs/Variants
for UBE4A

Disorders & Mutations
for UBE4A

Medical News
for UBE4A

Publications
for UBE4A

Licensable Technologies
for UBE4A

Services
for UBE4A