UBE4A Gene
protein-coding GIFtS: 62
GCID: GC11P118264
|
|
ubiquitination factor E4A(Previous names: ubiquitination factor E4A (homologous to yeast UFD2), ubiquitination...)
| |
Aliases
for UBE4A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitination Factor E4A1 2 | | Ubiquitination Factor E4A (UFD2 Homolog, Yeast)1 2 | | E41 2 5 | | KIAA01261 3 | | UFD21 2 5 | | Ubiquitination Factor E4A (Homologous To Yeast UFD2)1 | | UBOX21 2 | | Ubiquitin Conjugation Factor E4 A2 |
Export aliases for UBE4A gene to outside databasesPrevious GC identifers: GC11P120587 GC11P119742 GC11P117767 GC11P117735 GC11P114164 |
Summaries
for UBE4A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UBE4A:
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitinchain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination ofsecurin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogeneof this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multipleisoforms have been observed for this gene. (provided by RefSeq, Feb 2011)
UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139Function: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunctionwith E1, E2, and E3 (By similarity)
Gene Wiki entry for UBE4A
|
Genomic Views
for UBE4A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBE4A gene promoter:
TBP NF-1/L RP58 NF-1 RFX1 ATF-2 POU3F2 GATA-1 FOXO4 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBE4A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE4A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3UBE4A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P118264: view genomic region
(about GC identifiers)
Start:
|
118,230,300 bp from pter |
End:
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118,269,926 bp from pter |
Size:
|
39,627 bases |
Orientation:
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plus strand |
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Proteins
for UBE4A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139 (See
protein sequence)Recommended Name: Ubiquitin conjugation factor E4 A Size: 1066 amino acids; 122561 Da
Sequence caution: Sequence=AAH52643.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=AAH62695.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;Sequence=BAA09475.2; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for UBE4A:1WGM (3D)
Secondary accessions: B0YJB6 Q2M1H0 Q6P5T4 Q7Z639Alternative splicing: 2 isoforms: Q14139-1 Q14139-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBE4A: NX_Q14139
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14139
UBE4A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001191006.1 NP_004779.2
ENSEMBL proteins: ENSP00000252108 ENSP00000387362 ENSP00000438918 Reactome Protein details: Q14139
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000151 | ubiquitin ligase complex |
IEA | -- | | GO:0005737 | cytoplasm |
IEA | -- |
UBE4A for ontologies About GeneDecksing
UBE4A Antibody Products:
Assay Products for UBE4A: |
Protein
Domains /
Families
for UBE4A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBE4A for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14139ProtoNet protein and cluster: Q14139 1 Blocks protein family: IPB003613 Zn-finger
UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139Similarity: Belongs to the ubiquitin conjugation factor E4 familySimilarity: Contains 1 U-box domain |
Function
for UBE4A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBE4A_HUMAN, Q14139Function: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunctionwith E1, E2, and E3 (By similarity) Genatlas biochemistry entry for UBE4A:ubiquitination factor E4A,homologous to yeast UFD2,expressed in brain,required for multiubiquitin chain assembly,inassociation with E1,E2,E3,related to Drosophila NOSA
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE4A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE4A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): UBE4A (NM_004788) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE4A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE4A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE4A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004842 | ubiquitin-protein ligase activity |
-- | -- | | GO:0005515 | protein binding |
IPI | -- | | GO:0034450 | ubiquitin-ubiquitin ligase activity |
IEA | -- |
UBE4A for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for UBE4A:
|
Pathways & Interactions
for UBE4A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Reactome Pathways for UBE4A
1 
Kegg Pathway (Kegg details for UBE4A):
UBE4A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBE4A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/16 Interacting proteins for UBE4A (Q141391, 3 ENSP000002521084) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000209 | protein polyubiquitination |
IEA | -- | | GO:0006511 | ubiquitin-dependent protein catabolic process |
IEA | -- |
UBE4A for ontologies About GeneDecksing
|
Drugs & Compounds
for UBE4A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBE4A
4 HMDB Compounds for UBE4A About this table
Search CenterWatch for drugs/clinical trials and news about UBE4A
|
Transcripts
for UBE4A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBE4A gene (2 alternative transcripts): NM_001204077.1 NM_004788.3 Unigene Cluster for UBE4A: Ubiquitination factor E4A Hs.75275 [show with all ESTs]Unigene Representative Sequence: NM_0047883 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000252108(uc001psw.3 uc001psv.3) ENST00000431736 ENST00000545354
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE4A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE4A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): UBE4A (NM_004788) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE4A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE4A |
Additional cDNA sequence: AF087968.1 AK296369.1 AK302328.1 AK307737.1 BC010938.1 BC030973.1 BC039240.1 BC052643.1 BC062695.1 BC111417.1 BC112367.1 D50916.1 18 DOTS entries: DT.101983809 DT.101966714 DT.95219286 DT.95228417 DT.92439681 DT.317845 DT.120693753 DT.40115731 DT.101965579 DT.92439680 DT.92439683 DT.95292093 DT.100744038 DT.100792366 DT.40314850 DT.91685705 DT.100645178 DT.317847 24/1072 AceView cDNA sequences (see all 1072): BG623427 AW328279 W76357 BM464836 AA035042 BU542659 BP871644 F18594 AA810789 BM833121 AA877923 BQ717371 CA866089 CD678226 AA278832 AA777895 AA291167 AI833043 AA862560 AI001866 CB242044 AA478793 F26425 AA720965
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for UBE4A (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | ^ |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | - | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 |
|---|
|
| SP1: | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for UBE4A
|
Expression
for UBE4A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBE4A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAGAGGCTG
About this image
See UBE4A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBE4A
SOURCE GeneReport for Unigene cluster: Hs.75275
SABiosciences Expression via Pathway-Focused PCR Arrays including UBE4A: | Ubiquitination (Ubiquitylation) Pathway in human mouse rat | | Ubiquitin Ligases in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE4A
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE4A |
Orthologs
for UBE4A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for UBE4A gene from 5/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
UBE4A1 |
ubiquitination factor E4A |
79.64(n)
88.27(a) |
|
419758 NM_001030910.1 NP_001026081.1 |
lizard
(Anolis carolinensis) |
Reptilia |
UBE4A6 |
-- |
85(a) |
1 ↔ 1 |
GL343767.1(84070-94259) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BJ041478.12 |
-- |
75.9(n) |
|
BJ041478.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
ube4a1 |
ubiquitination factor E4A (UFD2 homolog, yeast) |
70.64(n)
77.75(a) |
|
557121 XM_001922926.3 XP_001922961.2 |
fruit fly
(Drosophila melanogaster) |
Insecta |
BcDNA:LD344753
CG110701 |
ubiquitin-dependent protein catabolism3
CG110701 |
34(a)3
49.91(n)1
38.96(a)1 |
|
339321 NM_135216.31 NP_609060.11 |
ENSEMBL Gene Tree for UBE4A (if available)
TreeFam Gene Tree for UBE4A (if available) |
Paralogs
for UBE4A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBE4A gene
- UBE4B2
1 SIMAP similar gene for UBE4A using alignment to 4 protein entries: UBE4A_HUMAN (see all proteins):Ube4B
UBE4A for paralogs About GeneDecksing
|
Genomic Variants
for UBE4A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBE4A (118230300 - 118269926 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for UBE4A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE4A |
|
Disorders
/ Diseases
for UBE4A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBE4A for disorders About GeneDecksing
OMIM gene information: 603753
OMIM disorders: --
9  diseases for UBE4A: About MalaCardscrohn's disease scleroderma serous cystadenocarcinoma ovarian serous cystadenocarcinoma
cystadenocarcinoma inflammatory bowel disease conjunctivitis neuroblastoma
malaria
1 disease from the University of Copenhagen DISEASES database for UBE4A:Ovarian serous cystadenocarcinoma Export disorders for UBE4A gene to outside databases
|
Publications
for UBE4A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBE4A gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with UBE4A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. (PubMed id 10089879)1, 3 Koegl M....Jentsch S. (1999)
- Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2 Nagase T....Nomura N. (1995)
- Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissues. (PubMed id 15019985)1, 9 Contino G....Novelli G. (2004)
- Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. (PubMed id 18069675)1, 9 Sakiyama T....Tsubouchi H. (2008)
- [Differential expression of USP2, USP14 and UBE4A between ovarian serous cystadenocarcinoma and adjacent normal tissues] (PubMed id 17553343)1, 9 Yang Y....Yang H.J. (2007)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for UBE4A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE4A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBE4A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing UBE4A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBE4A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBE4A gene:
Search GeneIP for patents involving UBE4A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBE4A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for UBE4A | | OriGene shRNA RFP for UBE4A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE4A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE4A | | | OriGene Protein Over-expression Lysate for UBE4A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBE4A | | OriGene 3'-UTR Clone for UBE4A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE4A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE4A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBE4A | | OriGene Custom Protein Services for UBE4A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE4A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE4A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE4A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE4A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE4A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE4A |
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| | | | Search Tocris compounds for UBE4A |
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 | | | UBE4A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE4A |
|  |  |  | | | | ThermoFisher Antibody for UBE4A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE4A |
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