UBE3B Gene
protein-coding GIFtS: 57
GCID: GC12P109915
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|
ubiquitin protein ligase E3B
| |
Aliases
for UBE3B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin Protein Ligase E3B1 2 | | Ubiquitin-Protein Ligase E3B2 | | EC 6.3.2.-3 | | EC 6.3.28 |
Export aliases for UBE3B gene to outside databasesPrevious GC identifers: GC12P108973 GC12P109754 GC12P108378 GC12P106933 |
Summaries
for UBE3B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UBE3B:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes,E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers theubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longerisoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorterisoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes.Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. (provided byRefSeq, Jul 2012)
UniProtKB/Swiss-Prot: UBE3B_HUMAN, Q7Z3V4Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of athioester and then directly transfers the ubiquitin to targeted substrates (By similarity)
|
Genomic Views
for UBE3B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBE3B gene promoter:
FAC1 HOXA3 GCNF-1 GCNF GCNF-2 Nkx5-1 YY1
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBE3B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE3B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.11 Ensembl cytogenetic band: 12q24.11 HGNC cytogenetic band: 12q24.12UBE3B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P109915: view genomic region
(about GC identifiers)
Start:
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109,915,207 bp from pter |
End:
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109,974,507 bp from pter |
Size:
|
59,301 bases |
Orientation:
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plus strand |
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Proteins
for UBE3B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBE3B_HUMAN, Q7Z3V4 (See
protein sequence)Recommended Name: Ubiquitin-protein ligase E3B Size: 1068 amino acids; 123098 Da
Secondary accessions: A5D8Z3 Q05BX9 Q659F7 Q7Z7Q1 Q9BXZ4Alternative splicing: 3 isoforms: Q7Z3V4-1 Q7Z3V4-2 Q7Z3V4-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBE3B: NX_Q7Z3V4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z3V4
2 DME Specific Peptides for UBE3B (Q7Z3V4)
UBE3B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001257378.1 NP_001257379.1 NP_001257380.1 NP_569733.2 NP_904324.1
ENSEMBL proteins: ENSP00000391529 ENSP00000440585 ENSP00000443131 ENSP00000340596 ENSP00000342614 ENSP00000443565 ENSP00000395802 ENSP00000437694 ENSP00000442825 ENSP00000446233 ENSP00000442276 ENSP00000280774 Reactome Protein details: Q7Z3V4
Human Recombinant Protein Products for UBE3B:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
UBE3B for ontologies About GeneDecksing
UBE3B Antibody Products:
Assay Products for UBE3B: |
Protein
Domains /
Families
for UBE3B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBE3B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7Z3V4ProtoNet protein and cluster: Q7Z3V4 1 Blocks protein family: IPB000569 HECT domain (Ubiquitin-protein ligase)
UniProtKB/Swiss-Prot: UBE3B_HUMAN, Q7Z3V4Similarity: Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domainSimilarity: Contains 1 IQ domain |
Function
for UBE3B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: UBE3B_HUMAN, Q7Z3V4Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of athioester and then directly transfers the ubiquitin to targeted substrates (By similarity) Enzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004842 | ubiquitin-protein ligase activity |
IBA | -- | | GO:0016881 | acid-amino acid ligase activity |
-- | -- |
UBE3B for ontologies About GeneDecksing
Phenotypes:
5 GenomeRNAi human phenotypes for UBE3B:
8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ube3b):
UBE3B for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE3B (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE3B (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): UBE3B (NM_183415) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE3B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE3B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE3B |
|
Pathways & Interactions
for UBE3B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | | | 3 | Ubiquitin-Proteasome Dependent Proteolysis | | | 4 | SMAD Signaling Network | | | 5 | PEDF Induced Signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for UBE3B
5 
Reactome Pathways for UBE3B
1 
Kegg Pathway (Kegg details for UBE3B):
UniProtKB/Swiss-Prot: UBE3B_HUMAN, Q7Z3V4Pathway: Protein modification; protein ubiquitination
UBE3B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBE3B
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
5/33 Interacting proteins for UBE3B (Q7Z3V43 ENSP000003405964) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006464 | cellular protein modification process |
-- | -- | | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
IBA | -- |
UBE3B for ontologies About GeneDecksing
|
Drugs & Compounds
for UBE3B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBE3B
4 HMDB Compounds for UBE3B About this table
Search CenterWatch for drugs/clinical trials and news about UBE3B
|
Transcripts
for UBE3B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBE3B gene (6 alternative transcripts): NM_001270449.1 NM_001270450.1 NM_001270451.1 NM_130466.3 NM_183415.2 NM_183414.1 Unigene Cluster for UBE3B: Ubiquitin protein ligase E3B Hs.374067 [show with all ESTs]Unigene Representative Sequence: NM_13046614 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000434735(uc009zvj.1 uc001toq.3 uc001tos.3 uc001tot.3)
ENST00000539843 ENST00000536398(uc001ton.3) ENST00000539599 ENST00000342494(uc001top.3)
ENST00000340074(uc001tom.3) ENST00000540230(uc001tor.3) ENST00000449510(uc001too.1)
ENST00000537063 ENST00000535900 ENST00000539584 ENST00000538070(uc010sxp.1)
ENST00000535089 ENST00000280774
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE3B (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE3B (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): UBE3B (NM_183415) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE3B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE3B |
Additional cDNA sequence: AF130072.1 AF251046.2 AK056015.1 AK301036.1 AK304678.1 AK307385.1 BC013182.1 BC020348.1 BC032301.1 BC040155.1 BC051266.1 BC068221.1 BC108705.1 BC141880.1 BC144684.1 BC150637.1 BX537403.1 24 DOTS entries: DT.454561 DT.92441920 DT.99989375 DT.95313051 DT.95313053 DT.101983921 DT.99981676 DT.75127322 DT.100784663 DT.95179168 DT.100703058 DT.65286904 DT.207681 DT.40125574 DT.75103797 DT.92441918 DT.100695974 DT.92059583 DT.97812263 DT.100705342 DT.121205054 DT.75119309 DT.91741005 DT.91863694 24/400 AceView cDNA sequences (see all 400): AA323742 AI524358 AA781622 AA486538 BC032301 AA312078 AW576512 AI913742 NM_183415 AA644394 BX404957 BC020348 BQ061239 AI264287 AI522191 CR613548 BF529297 AA978104 AI394278 AW118987 BF059032 CA488803 AI038813 CR616108
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for UBE3B (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ |
|---|
|
| SP1: | | | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UBE3B
|
Expression
for UBE3B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBE3B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGATTTTTG
About this image
See UBE3B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBE3B
SOURCE GeneReport for Unigene cluster: Hs.374067
UniProtKB/Swiss-Prot: UBE3B_HUMAN, Q7Z3V4Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Array including UBE3B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE3B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UBE3B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE3B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE3B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE3B |
Orthologs
for UBE3B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBE3B gene from 6/24 species (see all 24) About this table
ENSEMBL Gene Tree for UBE3B (if available)
TreeFam Gene Tree for UBE3B (if available) |
Paralogs
for UBE3B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBE3B gene
- UBE3C2
6 SIMAP similar genes for UBE3B using alignment to 7 protein entries: UBE3B_HUMAN (see all proteins):UBE3A NEDD4L DKFZp564H223 HUWE1 SMURF2 WWP2
UBE3B for paralogs About GeneDecksing
|
Genomic Variants
for UBE3B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBE3B (109915207 - 109974507 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for UBE3B: --
Human Gene Mutation Database (HGMD): UBE3B
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE3B |
|
Disorders
/ Diseases
for UBE3B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBE3B for disorders About GeneDecksing
OMIM gene information: 608047
OMIM disorders: --
2  diseases for UBE3B: About MalaCardsautosomal dominant nonsyndromic deafness nonsyndromic deafness
1 disease from the University of Copenhagen DISEASES database for UBE3B:Blepharophimosis Human Genome Epidemiology (HuGE) Navigator: UBE3B (1 document)
Export disorders for UBE3B gene to outside databases
|
Publications
for UBE3B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBE3B gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with UBE3B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Characterization of the human UBE3B gene: structure, expression, evolution, and alternative splicing. (PubMed id 12837265)1, 2 Gong T.-W.L.... Lomax M.I. (2003)
- Deficiency for the ubiquitin ligase UBE3B in a blephar ophimosis-ptosis-intellectual-disability syndrome. (PubMed id 23200864)1 Basel-Vanagaite L....Borck G. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (PubMed id 20864672)1 Waterworth D.M....Sandhu M.S. (2010)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
- Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1 Meierhofer D.... Kaiser P. (2008)
- Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PubMed id 17672918)1 Szafranski K....Platzer M. (2007)
|
External Searches for UBE3B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE3B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBE3B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBE3B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBE3B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBE3B gene:
Search GeneIP for patents involving UBE3B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBE3B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UBE3B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE3B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE3B | | | OriGene Protein Over-expression Lysate for UBE3B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBE3B | | OriGene 3'-UTR Clone for UBE3B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE3B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE3B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBE3B | | OriGene Custom Protein Services for UBE3B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE3B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE3B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE3B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE3B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE3B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE3B |
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| | | | Search Tocris compounds for UBE3B |
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 | | | UBE3B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE3B |
|  |  |  |  | | | | Search ThermoFisher Antibodies for UBE3B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE3B |
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