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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UBE2Z Gene

protein-coding   GIFtS: 60
GCID: GC17P046985

Ubiquitin-Conjugating Enzyme E2Z

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ubiquitin-Conjugating Enzyme E2Z1 2     EC 6.3.2.193 8
UBA6-Specific Enzyme E21 2     USE12
Uba6-Specific E2 Conjugating Enzyme 12 3     Ubiquitin-Conjugating Enzyme E2 Z2
Ubiquitin Carrier Protein Z2 3     Use13
Ubiquitin-Protein Ligase Z2 3     

External Ids:    HGNC: 258471   Entrez Gene: 652642   Ensembl: ENSG000001592027   OMIM: 6113625   UniProtKB: Q9H8323   

Export aliases for UBE2Z gene to outside databases

Previous GC identifers: GC17P044341 GC17P042357


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UBE2Z Gene:
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis.
(provided by RefSeq, Feb 2012)

GeneCards Summary for UBE2Z Gene: 
UBE2Z (ubiquitin-conjugating enzyme E2Z) is a protein-coding gene. Diseases associated with UBE2Z include gigantism, and among its related super-pathways are Antigen processing: Ubiquitination & Proteasome degradation and Immune System. GO annotations related to this gene include ubiquitin-protein ligase activity and ATP binding. An important paralog of this gene is UBE2O.

UniProtKB/Swiss-Prot: UBE2Z_HUMAN, Q9H832
Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for
UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UBE2Z gene promoter:
         GR   Pax-5   Bach2   RREB-1   Evi-1   PPAR-alpha   HSF2   Chx10   ARP-1   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUBE2Z promoter sequence
   Search SABiosciences Chromatin IP Primers for UBE2Z

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2Z


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.32   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.32

UBE2Z Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBE2Z gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P046985:  view genomic region     (about GC identifiers)

Start:
46,985,731 bp from pter      End:
47,006,422 bp from pter
Size:
20,692 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: UBE2Z_HUMAN, Q9H832 (See protein sequence)
Recommended Name: Ubiquitin-conjugating enzyme E2 Z  
Size: 354 amino acids; 38210 Da
Subcellular location: Cytoplasm. Nucleus
Sequence caution: Sequence=AAH15890.1; Type=Erroneous initiation; Sequence=BAB14724.1; Type=Erroneous initiation;
Secondary accessions: A6N8M6 A6NC60 Q7L354 Q8TCM4 Q9H893
Alternative splicing: 2 isoforms:  Q9H832-1   Q9H832-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for UBE2Z: NX_Q9H832

Explore proteomics data for UBE2Z at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H832

  • 4 DME Specific Peptides for UBE2Z (Q9H832)
     MQDPFGEKRGHFDYQSLL  GDSKNYNECIRHETIRVAVC  SSVLISIQSLMTENPYHNEPGFEQERH  FRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLS 

    UBE2Z Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    UBE2Z Protein Expression
    REFSEQ proteins: NP_075567.2  
    ENSEMBL proteins: 
     ENSP00000354201   ENSP00000424543   ENSP00000425398   ENSP00000461147   ENSP00000460759  
     ENSP00000459473  
    Reactome Protein details: Q9H832
    Human Recombinant Protein Products for UBE2Z: 
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    Novus Biologicals UBE2Z Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for UBE2Z 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    UBE2Z for ontologies           About GeneDecksing



    UBE2Z Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    UBE2: Ubiquitin-conjugating enzymes E2

    2 InterPro protein domains:
     IPR016135 UBQ-conjugating_enzyme/RWD
     IPR000608 UBQ-conjugat_E2

    Graphical View of Domain Structure for InterPro Entry Q9H832

    ProtoNet protein and cluster: Q9H832

    1 Blocks protein domain: IPB000608 Ubiquitin-conjugating enzymes

    UniProtKB/Swiss-Prot: UBE2Z_HUMAN, Q9H832
    Similarity: Belongs to the ubiquitin-conjugating enzyme family


    UBE2Z for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: UBE2Z_HUMAN, Q9H832
    Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for
    UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation
    Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine

         Enzyme Number (IUBMB): EC 6.3.2.191 2

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0016881acid-amino acid ligase activity ----
         
    UBE2Z for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for UBE2Z:
     Increased cell death HMECs cel  Synthetic lethal with Ras  Wnt reporter downregulated 

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidUBE2Z 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for UBE2Z About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Antigen processing: Ubiquitination & Proteasome degradation
    Antigen processing: Ubiquitination & Proteasome degradation0.83
    Ubiquitin mediated proteolysis0.36
    Class I MHC mediated antigen processing & presentation0.83
    2Immune System
    Immune System0.56
    Adaptive Immune System0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for UBE2Z
        Antigen processing: Ubiquitination & Proteasome degradation
    Adaptive Immune System
    Class I MHC mediated antigen processing & presentation
    Immune System


    1         Kegg Pathway  (Kegg details for UBE2Z):
        Ubiquitin mediated proteolysis

    UniProtKB/Swiss-Prot: UBE2Z_HUMAN, Q9H832
    Pathway: Protein modification; protein ubiquitination


    UBE2Z for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBE2Z

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/52 Interacting proteins for UBE2Z (Q9H8322, 3 ENSP000003542014) via UniProtKB, MINT, STRING, and/or I2D (see all 52)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLEKHF2Q9H8W42, 3, ENSP000003223734MINT-67937 I2D: score=5 STRING: ENSP00000322373
    LPLP068582, 3MINT-63417 I2D: score=5 
    RNF5Q999423, ENSP000003642354I2D: score=2 STRING: ENSP00000364235
    ENSG00000183574Q999423I2D: score=2 
    ENSG00000223767Q999423I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--

    UBE2Z for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UBE2Z

    4 HMDB Compounds for UBE2Z    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--

    Search CenterWatch for drugs/clinical trials and news about UBE2Z

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for UBE2Z gene: 
    NM_023079.4  

    Unigene Cluster for UBE2Z:

    Ubiquitin-conjugating enzyme E2Z
    Hs.514297  [show with all ESTs]
    Unigene Representative Sequence: AK091644
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000360943(uc002ioi.3) ENST00000508468 ENST00000506498 ENST00000511373
    ENST00000504684 ENST00000513342 ENST00000506271 ENST00000514948
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidUBE2Z 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2Z
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2Z

    Additional mRNA sequence: 

    AB025426.1 AK023917.1 AK024030.1 AK091644.1 AK122770.1 AK130303.1 AK296865.1 AL713782.1 
    BC015169.1 BC015890.1 CR457322.1 EF623992.1 

    22 DOTS entries:

    DT.101966986  DT.456081  DT.100826843  DT.97851377  DT.99957834  DT.100826844  DT.120911283  DT.120911314 
    DT.120911417  DT.75149705  DT.91759275  DT.91759295  DT.95223440  DT.101984794  DT.102844558  DT.120911414 
    DT.120911425  DT.75101708  DT.91759293  DT.100649701  DT.219192  DT.99942923 

    24/436 AceView cDNA sequences (see all 436):

    AL037894 AI561344 BQ029546 AW006025 AI280694 CA952898 AI138900 BI757130 
    AA445998 BE855832 BM450804 BM803464 BM995039 AI095613 AI215138 BE857552 
    CB852004 CB138049 AA278442 AA460943 BU181041 BQ223043 BQ130583 AA845421 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2Z    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b
    SP1:        -     -           -           -                                       
    SP2:                          -     -     -                                       
    SP3:                                      -                                       
    SP4:                                                                              
    SP5:                          -           -                                       


    ECgene alternative splicing isoforms for UBE2Z

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UBE2Z expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGGCATAG
    UBE2Z Expression
    About this image


    See UBE2Z Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UBE2Z

    SOURCE GeneReport for Unigene cluster: Hs.514297

    UniProtKB/Swiss-Prot: UBE2Z_HUMAN, Q9H832
    Tissue specificity: Widely expressed. Highly in placenta, pancreas, spleen and testis

        SABiosciences Expression via Pathway-Focused PCR Array including UBE2Z: 
              Ubiquitination (Ubiquitylation) Pathway in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2Z

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for UBE2Z gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ube2z1 , 5 ubiquitin-conjugating enzyme E2Z (putative)1, 5 94.26(n)1
    99.44(a)1
      11 (59.28 cM)5
    2684701  NM_172300.31  NP_758504.31 
     960474325 
    chicken
    (Gallus gallus)
    Aves UBE2Z1 ubiquitin-conjugating enzyme E2Z 78.91(n)
    81.05(a)
      419991  XM_418113.3  XP_418113.1 
    lizard
    (Anolis carolinensis)
    Reptilia UBE2Z6
    Uncharacterized protein
    72(a)
    1 ↔ 1
    6(75952159-75969979)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC691552 hypothetical protein MGC69155 79.33(n)    BC059343.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.288572 Transcribed sequence with moderate similarity to protein more 77.78(n)    CF999866.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RAD66
    Ubiquitin-conjugating enzyme (E2), involved in pos...
    24(a)
    1 → many
    VII(393986-394504)


    ENSEMBL Gene Tree for UBE2Z (if available)
    TreeFam Gene Tree for UBE2Z (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UBE2Z gene
    UBE2O2  BIRC62  
    12 SIMAP similar genes for UBE2Z using alignment to 7 protein entries:     UBE2Z_HUMAN (see all proteins):
    UBE2D3    UBE2D4    HR6A    UBE2D2    UBE2O    UBE2N
    UBE2DNL    UBE2D1    BIRC6    UBE2B    UBE2T    UBE2G2

    UBE2Z for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/442 SNPs in UBE2Z are shown (see all 442)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs286354661,2
    C,F--46983820(+) CCTGCG/ATGACA 1 -- us2k19Minor allele frequency- A:0.27NA WA EA 370
    rs2015663981,2
    --46983887(+) GACTC-/TTTTTT 1 -- us2k10--------
    rs99021311,2
    C,F,A--46984042(+) ccggcT/Aaattt 1 -- us2k12Minor allele frequency- A:0.50NA 4
    rs348997721,2
    C,F,H--46984425(+) TGAGAC/TGGAGT 1 -- us2k14Minor allele frequency- T:0.08NS NA 678
    rs1837007301,2
    C--46984584(+) TTTTTA/GGTAGA 1 -- us2k10--------
    rs562366201,2
    C--46984832(+) TGCAAC/ACTCCG 1 -- us2k11Minor allele frequency- A:0.00NA 2
    rs558193561,2
    C--46984859(+) GATCCT/ACCTGC 1 -- us2k11Minor allele frequency- A:0.00NA 2
    rs1880172911,2
    --46984958(+) GTTAGA/GCTGGT 1 -- us2k10--------
    rs1132122621,2
    C,F--46985088(+) AGAATC/TCTCAG 1 -- us2k10--------
    rs1807844881,2
    --46985094(+) CTCAGC/GGTTTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for UBE2Z (46985731 - 47006422 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for UBE2Z:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv2073CNV Insertion18451855
    nsv482969CNV Loss15286789
    nsv833472CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611362    OMIM disorders: --

    2 diseases for UBE2Z:    About MalaCards
    gigantism    


    UBE2Z for disorders           About GeneDecksing

    Genetic Association Database (GAD): UBE2Z
    Human Genome Epidemiology (HuGE) Navigator: UBE2Z (1 document)

    Export disorders for UBE2Z gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for UBE2Z gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with UBE2Z)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. (PubMed id 17597759)1, 2, 3 Jin J.... Harper J.W. (2007)
    2. Cloning and characterization of a gene encoding the human putative ubiquitin conjugating enzyme E2Z (UBE2Z). (PubMed id 17160626)1, 2, 9 Gu X.... Mao Y. (2007)
    3. Large-scale association analysis identifies 13 new su sceptibility loci for coronary artery disease. (PubMed id 21378990)1, 4 Schunkert H....Samani N.J. (2011)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Bcl2-associated Athanogene 3 Interactome Analysis Reve als a New Role in Modulating Proteasome Activity. (PubMed id 23824909)1 Chen Y....Ge F. (2013)
    7. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. Protein phosphatase 1a interacting proteins in the hum an brain. (PubMed id 22321011)1 Esteves S.L....da Cruz e Silva E.F. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 65264 HGNC: 25847 AceView: FLJ13855 Ensembl:ENSG00000159202 euGenes: HUgn65264
    ECgene: UBE2Z Kegg: 65264 H-InvDB: UBE2Z

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UBE2Z Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for UBE2Z gene:
    Search GeneIP for patents involving UBE2Z

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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