UBE2W Gene
protein-coding GIFtS: 56
GCID: GC08M074692
|
|
ubiquitin-conjugating enzyme E2W (putative)
| |
Aliases
for UBE2W gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin-Conjugating Enzyme E2W (Putative)1 2 | | UBC162 3 | | Ubiquitin Carrier Protein W2 3 | | EC 6.3.2.193 8 | | Ubiquitin-Conjugating Enzyme 162 3 | | FLJ110111 | | Ubiquitin-Protein Ligase W2 3 | | Ubiquitin-Conjugating Enzyme 2W2 | | UBC-162 3 | | Ubiquitin-Conjugating Enzyme E2 W2 |
Export aliases for UBE2W gene to outside databasesPrevious GC identifers: GC08M074866 GC08M074702 GC08M070193 |
Summaries
for UBE2W gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UBE2W:
This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) andligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded proteinpromotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNAdamage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcriptvariants. (provided by RefSeq, Aug 2012)
UniProtKB/Swiss-Prot: UBE2W_HUMAN, Q96B02Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzesmonoubiquitination. Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination ofSTUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length ofubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC)treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Invitro catalyzes 'Lys-11'-linked polyubiquitination
|
Genomic Views
for UBE2W gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008183.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBE2W gene promoter:
STAT5B AML1a HNF-4alpha2 STAT5A Egr-4 HNF-4alpha1 GATA-1 AREB6 deltaCREB Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBE2W
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2W |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q21.11 Ensembl cytogenetic band: 8q21.11 HGNC cytogenetic band: 8q21.11UBE2W Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M074692: view genomic region
(about GC identifiers)
Start:
|
74,692,332 bp from pter |
End:
|
74,791,145 bp from pter |
Size:
|
98,814 bases |
Orientation:
|
minus strand |
|
Proteins
for UBE2W gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBE2W_HUMAN, Q96B02 (See
protein sequence)Recommended Name: Ubiquitin-conjugating enzyme E2 W Size: 151 amino acids; 17331 Da
Subunit: Homodimer. Interacts with FANCL. Interacts with STUB1/CHIP (By similarity)
Subcellular location: Nucleus. Note=In the nucleus, colocalizes with FANCL
1 PDB 3D structure from  and Proteopedia  for UBE2W:2A7L (3D)
Secondary accessions: B4DIV1 Q1XBE0 Q9H823 Q9HAG6 Q9NV07Alternative splicing: 3 isoforms: Q96B02-1 Q96B02-2 Q96B02-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBE2W: NX_Q96B02
Post-translational modifications:
Ubiquitinated in vitro in the presence of FANCL (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96B02
2 DME Specific Peptides for UBE2W (Q96B02)
UBE2W Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001001481.2 NP_001257944.1 NP_060769.4
ENSEMBL proteins: ENSP00000428835 ENSP00000428813 ENSP00000414771 ENSP00000397453 ENSP00000430254 ENSP00000429136 ENSP00000403764 Reactome Protein details: Q96B02
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
UBE2W for ontologies About GeneDecksing
UBE2W Antibody Products:
Assay Products for UBE2W: |
Protein
Domains /
Families
for UBE2W gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBE2W for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96B02ProtoNet protein and cluster: Q96B02 1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes
UniProtKB/Swiss-Prot: UBE2W_HUMAN, Q96B02Similarity: Belongs to the ubiquitin-conjugating enzyme family |
Function
for UBE2W gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBE2W_HUMAN, Q96B02Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzesmonoubiquitination. Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination ofSTUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length ofubiquitin chain attached to STUB1/CHIP substrates by ATXN3. After UV irradiation, but not after mitomycin-C (MMC)treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Invitro catalyzes 'Lys-11'-linked polyubiquitinationCatalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysineEnzyme Number (IUBMB): EC 6.3.2.191 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2W (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2W (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 2): UBE2W (NM_018299) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2W | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2W |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2W |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
UBE2W for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for UBE2W:
|
Pathways & Interactions
for UBE2W gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Reactome Pathways for UBE2W
1 
Kegg Pathway (Kegg details for UBE2W):
UniProtKB/Swiss-Prot: UBE2W_HUMAN, Q96B02Pathway: Protein modification; protein ubiquitination
UBE2W for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBE2W
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/83 Interacting proteins for UBE2W (Q96B022, 3 ENSP000003974534) via UniProtKB, MINT, STRING, and/or I2D (see all 83)
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006281 | DNA repair |
IEA | -- | | GO:0006513 | protein monoubiquitination |
IMP | -- | | GO:0006515 | misfolded or incompletely synthesized protein catabolic process |
ISS | -- | | GO:0043161 | proteasomal ubiquitin-dependent protein catabolic process |
ISS | -- | | GO:0070979 | protein K11-linked ubiquitination |
IDA | -- |
UBE2W for ontologies About GeneDecksing
|
Drugs & Compounds
for UBE2W gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBE2W
4 HMDB Compounds for UBE2W About this table
Search CenterWatch for drugs/clinical trials and news about UBE2W
|
Transcripts
for UBE2W gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBE2W gene (4 alternative transcripts): NM_001001481.2 NM_001271015.1 NM_018299.4 NM_001001482.1 Unigene Cluster for UBE2W: Ubiquitin-conjugating enzyme E2W (putative) Hs.128841 [show with all ESTs]Unigene Representative Sequence: NM_0010014817 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523278 ENST00000517608(uc003xzu.3 uc003xzv.3) ENST00000422906(uc003xzw.3)
ENST00000419880 ENST00000519277 ENST00000519255 ENST00000453587(uc003xzt.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2W (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2W (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): UBE2W (NM_018299) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2W | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2W |
Additional cDNA sequence: AK001873.1 AK021735.1 AK024050.1 AK123531.1 AK225554.1 AK295792.1 AL833723.1 AY948289.1 BC010900.1 BC016326.1 BX538145.1 BX648427.1 CR457275.1 NR_073119.1 NR_073120.1 NR_073121.1 12 DOTS entries: DT.100821509 DT.100640421 DT.212257 DT.102842 DT.75189561 DT.40127576 DT.95375728 DT.100821506 DT.65287833 DT.95315344 DT.212259 DT.40250693 24/446 AceView cDNA sequences (see all 446): Z40600 BU178550 AW242030 F01972 AI301037 AA252578 AI351764 AI359541 AL600889 NM_018299 BX399252 CA311925 AA593175 AL708648 BI553990 AA813913 BG941862 BC016326 BM682964 BQ721043 N51374 BU150974 AA256013 AI040886
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2W About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for UBE2W
|
Expression
for UBE2W gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBE2W expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See UBE2W Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBE2W
SOURCE GeneReport for Unigene cluster: Hs.128841
UniProtKB/Swiss-Prot: UBE2W_HUMAN, Q96B02Tissue specificity: Widely expressed, with highest expression in brain, liver, pancreas and heart
SABiosciences Expression via Pathway-Focused PCR Array including UBE2W: | Ubiquitination (Ubiquitylation) Pathway in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2W
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UBE2W | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2W | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2W | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2W |
Orthologs
for UBE2W gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBE2W gene from 8/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ube2w1 , 5 |
ubiquitin-conjugating enzyme E2W (putative)1, 5 |
94.07(n)1
95.56(a)1 |
|
1 (5.10 cM)5
667991 NM_025773.31 NP_080049.21
165697825 |
chicken
(Gallus gallus) |
Aves |
UBE2W1 |
ubiquitin-conjugating enzyme E2W (putative) |
90.95(n)
99.34(a) |
|
420185 NM_001199481.1 NP_001186410.1 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.199992 |
Transcribed sequence with strong similarity to protein refNP_060769.1 (H.sapiens) hypothetical protein FLJ11011 [Homo sapiens] less |
85.94(n) |
|
AL890226.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.176652 |
Danio rerio clone RK115A3B02 hypothetical protein FLJ11011 mRNA, complete cds less |
83.05(n) |
|
AY398346.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG72201 |
CG7220 |
65.07(n)
72.6(a) |
|
36129 NM_136760.3 NP_610604.3 |
worm
(Caenorhabditis elegans) |
Secernentea |
ubc-161 |
Protein UBC-16 |
58.85(n)
61.38(a) |
|
173354 NM_061186.3 NP_493587.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
UBC161 |
putative ubiquitin-conjugating enzyme E2 16 |
59.71(n)
53.96(a) |
|
843880 NM_106198.4 NP_565110.1 |
rice
(Oryza sativa) |
Liliopsida |
---- |
ubiquitin-conjugating enzyme E2 W, putative, expre...ubiquitin-conjugating enzyme E2 W, putative, expre... |
48(a)48(a) |
many ↔ manymany ↔ many |
12(27261821-27265138) 3(27104494-27109585) |
ENSEMBL Gene Tree for UBE2W (if available)
TreeFam Gene Tree for UBE2W (if available) |
Paralogs
for UBE2W gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBE2W gene
- UBE2D32 ENSG000002586772 UBE2L62 UBE2D12 UBE2D22 UBE2E32 UBE2D42 UBE2E12
- UBE2E22 UBE2L32
14 SIMAP similar genes for UBE2W using alignment to 5 protein entries: UBE2W_HUMAN (see all proteins):UBE2N UBE2E3 UBE2E2 UBE2E1 UBE2B HR6A
UBE2A UBE2D4 UBE2C UBE2D2 UBE2D3 UBE2I
UBE2D1 UBE2L6
UBE2W for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for UBE2W
PGOHUM00000259569
|
Genomic Variants
for UBE2W gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBE2W (74692332 - 74791145 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for UBE2W
1 Indel: 10914 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2W |
|
Disorders
/ Diseases
for UBE2W gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBE2W for disorders About GeneDecksing
OMIM gene information: 614277
OMIM disorders: --
3  diseases for UBE2W: About MalaCardsfanconi's anemia anemia malaria
Export disorders for UBE2W gene to outside databases
|
Publications
for UBE2W gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBE2W gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with UBE2W) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- UBE2W interacts with FANCL and regulates the monoubiq uitination of Fanconi anemia protein FANCD2. (PubMed id 21229326)1, 2 Zhang Y....Huang P. (2011)
- Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI. (PubMed id 19111657)1, 2 Alpi A.F....Patel K.J. (2008)
- Cloning, characterization and subcellular localization of a gene encoding a human Ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana UBC-16 gene product. (PubMed id 16368532)1, 2 Yin G....Mao Y. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. (PubMed id 17873885)1, 9 Christensen D.E....Klevit R.E. (2007)
- Profiling of autoantibodies in IgA nephropathy, an int egrative antibiomics approach. (PubMed id 22157707)1 Sigdel T.K....Lafayette R.A. (2011)
- E3 ligases determine ubiquitination site and conjugat e type by enforcing specificity on E2 enzymes. (PubMed id 21965653)1 David Y....Navon A. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
|
External Searches for UBE2W gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE2W gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBE2W gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBE2W gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBE2W | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBE2W gene:
Search GeneIP for patents involving UBE2W
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for UBE2W gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UBE2W | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE2W | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2W | | | OriGene Protein Over-expression Lysate for UBE2W | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBE2W | | OriGene 3'-UTR Clone for UBE2W | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2W | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2W | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for UBE2W | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBE2W | | OriGene Custom Protein Services for UBE2W | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE2W | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2W | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2W | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE2W | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2W | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2W |
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| | | | Search Tocris compounds for UBE2W |
| |  |  |  |  | | | | | | Recombinant Protein for UBE2W |
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 | | | UBE2W Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2W |
|  |  |  | | | | Search ThermoFisher Antibodies for UBE2W |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2W |
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