UBE2V1 Gene
protein-coding GIFtS: 60
GCID: GC20M048698
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|
ubiquitin-conjugating enzyme E2 variant 1
(Previous symbol: UBE2V)
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Aliases
for UBE2V1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin-Conjugating Enzyme E2 Variant 11 2 | | UEV12 3 5 | | CROC-11 2 3 | | UEV1A1 2 | | CROC11 2 3 | | TRAF6-Regulated IKK Activator 1 Beta Uev1A2 3 | | UBE2V1 2 3 | | CIR12 | | UEV-11 2 3 | | DNA-Binding Protein2 |
Export aliases for UBE2V1 gene to outside databasesPrevious GC identifers: GC20M048426 GC20M049336 GC20M049383 GC20M048132 GC20M045447 |
Summaries
for UBE2V1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UBE2V1:
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. Theyhave sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that iscritical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can causetranscriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control ofdifferentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoformshave been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription ofthis gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion proteincomprised of sequence sharing identity with each individual gene product. (provided by RefSeq, Apr 2012)
UniProtKB/Swiss-Prot: UB2V1_HUMAN, Q13404Function: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis ofnon-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK anddoes not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediatedby IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control ofprogress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributesto the survival of cells after DNA damage. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2Nheterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes
Gene Wiki entry for UBE2V1
|
Genomic Views
for UBE2V1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBE2V1 gene promoter:
NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBE2V1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2V1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.2 Ensembl cytogenetic band: 20q13.13 HGNC cytogenetic band: 20q13.2UBE2V1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M048698: view genomic region
(about GC identifiers)
Start:
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48,697,661 bp from pter |
End:
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48,732,496 bp from pter |
Size:
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34,836 bases |
Orientation:
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minus strand |
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Proteins
for UBE2V1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UB2V1_HUMAN, Q13404 (See
protein sequence)Recommended Name: Ubiquitin-conjugating enzyme E2 variant 1 Size: 147 amino acids; 16495 Da
Subunit: Heterodimer with UBE2N. Interacts (UBE2V2-UBE2N heterodimer) with the E3 ligase STUB1 (via the U-box domain);the complex has a specific 'Lys-63'-linked polyubiquitination activity. Interacts with TRAF6
Subcellular location: Nucleus. Note=Excluded from the nucleolus
Miscellaneous: In human, TMEM189/KUA and UBE2V1/UEV1 are adjacent genes which can produce independent proteins and canalso be fused to form a TMEM189-UBE2V1 hybrid protein
Sequence caution: Sequence=AAH08944.2; Type=Erroneous initiation; Sequence=CAC16955.2; Type=Erroneous initiation;Note=Translation N-terminally shortened;
3 PDB 3D structures from  and Proteopedia  for UBE2V1:2A4D (3D)
2C2V (3D)
2HLW (3D)
Secondary accessions: E1P629 Q13403 Q13532 Q5TGE0 Q5TGE3 Q96H34 Q9GZT0 Q9GZW1 Q9H4J3 Q9H4J4 Q9UKL1Q9UM48 Q9UM49 Q9UM50Alternative splicing: 6 isoforms: Q13404-4 Q13404-1 Q13404-2 Q13404-6 Q13404-7 Q13404-8 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for UBE2V1: NX_Q13404
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13404
UBE2V1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (11 alternative transcripts):
NP_001027459.1 NP_001244322.1 NP_001244323.1 NP_001244324.1 NP_001244325.1 NP_001244326.1 NP_001244327.1 NP_001244328.1 NP_068823.2 NP_071887.1 NP_954595.1
ENSEMBL proteins: ENSP00000360720 ENSP00000360739 ENSP00000340305 ENSP00000407770 ENSP00000360742 ENSP00000421351 ENSP00000395264 Reactome Protein details: Q13404
Human Recombinant Protein Products for UBE2V1:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
UBE2V1 for ontologies About GeneDecksing
UBE2V1 Antibody Products:
Assay Products for UBE2V1: |
Protein
Domains /
Families
for UBE2V1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBE2V1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13404ProtoNet protein and cluster: Q13404 1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes
UniProtKB/Swiss-Prot: UB2V1_HUMAN, Q13404Similarity: Belongs to the ubiquitin-conjugating enzyme family |
Function
for UBE2V1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: UB2V1_HUMAN, Q13404Function: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis ofnon-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK anddoes not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediatedby IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control ofprogress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributesto the survival of cells after DNA damage. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2Nheterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genesInduction: Down-regulated during differentiation of cultured colon adenocarcinoma cells Genatlas biochemistry entry for UBE2V1:ubiquitin conjugating enzyme E2 variant 1,expressed as at least four isoforms,transcriptional activator of FOSpromoter,underexpressed in hormone refractory prostate cancer,potentially involved in the control of differentiation
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
UBE2V1 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2V1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2V1 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): UBE2V1 (NM_022442) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2V1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2V1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2V1 |
|
Pathways & Interactions
for UBE2V1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/15 super-pathways (see all 15) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | TRAF6 Mediated Induction of proinflammatory cytokines | | | 2 | IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | | | 3 | Antigen processing: Ubiquitination & Proteasome degradation | | | 4 | Immune System | | | 5 | Immune response_IL-1 signaling pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for UBE2V1
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for UBE2V1
2  GeneGo (Thomson Reuters) Pathways for UBE2V1
1  BioSystems Pathway for UBE2V1
5/35 
Reactome Pathways for UBE2V1 (see all 35)
UBE2V1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UBE2V1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/46 Interacting proteins for UBE2V1 (Q134041, 2, 3 ENSP000003403054) via UniProtKB, MINT, STRING, and/or I2D (see all 46)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
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| UBE2N | P610881, 2, 3, ENSP000003161764 | EBI-1050671,EBI-1052908 MINT-50197 I2D:
score=5 STRING: ENSP00000316176 | | ZNRF1 | Q8ND251, 3, ENSP000003350914 | EBI-1050671,EBI-2129250 I2D:
score=2 STRING: ENSP00000335091 | | XIAP | P981701, 3, ENSP000003478584 | EBI-1050671,EBI-517127 I2D:
score=2 STRING: ENSP00000347858 | | BIRC8 | Q96P093, ENSP000004129574 | I2D:
score=2 STRING: ENSP00000412957 | | MKRN3 | Q130643, ENSP000003138814 | I2D:
score=2 STRING: ENSP00000313881 |
About this table
Gene Ontology (GO): 5/18 biological process terms (GO ID links to tree view) (see all 18): About this table
UBE2V1 for ontologies About GeneDecksing
|
Drugs & Compounds
for UBE2V1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBE2V1
Search CenterWatch for drugs/clinical trials and news about UBE2V1 / UB2V1
|
Transcripts
for UBE2V1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBE2V1 gene (11 alternative transcripts): NM_001032288.2 NM_001257393.1 NM_001257394.1 NM_001257395.1 NM_001257396.1 NM_001257397.1 NM_001257398.1 NM_001257399.1 NM_021988.5 NM_022442.5 NM_199144.2 Unigene Cluster for UBE2V1: Ubiquitin-conjugating enzyme E2 variant 1 Hs.420529 [show with all ESTs]Unigene Representative Sequence: NM_19920318/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000371657 ENST00000396059 ENST00000371674(uc002xvb.3 uc002xva.3)
ENST00000340309(uc002xve.3) ENST00000415862 ENST00000371677(uc002xvd.3)
ENST00000483534 ENST00000486653 ENST00000490555 ENST00000493090 ENST00000467839
ENST00000472923 ENST00000432266 ENST00000470565 ENST00000490289 ENST00000461960
ENST00000462217 ENST00000473860
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2V1 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2V1 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): UBE2V1 (NM_022442) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2V1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2V1 |
Additional cDNA sequence: AB044550.1 AF049671.1 AF155120.1 AK023028.1 AK304595.1 AK314754.1 AY008273.1 BC000468.2 BC005215.1 BC008944.2 BC018893.2 BC142966.1 BC144612.1 BT007382.1 BX647511.1 BX648147.1 NR_027889.1 NR_047553.1 NR_047554.1 NR_047555.1 NR_047556.1 U39360.1 U97280.1 U97281.1 24/65 DOTS entries (see all 65): DT.87017867 DT.100881989 DT.100881988 DT.86999436 DT.95190771 DT.100882004 DT.91927742 DT.101965698 DT.95279545 DT.97799662 DT.320480 DT.100758874 DT.100672690 DT.95108243 DT.100881995 DT.100881998 DT.120838136 DT.100881974 DT.75156062 DT.100881992 DT.120837985 DT.40305392 DT.97859427 DT.92467447 24/1050 AceView cDNA sequences (see all 1050): BG943639 BG105425 BU628670 CR612804 AI872729 BU955838 AL547316 AA641136 BM792698 CR597636 CR615526 BE619076 NM_022442 BQ889364 AA808342 BG034562 BM994499 AA972662 CR615402 CR607429 AI056308 CR596657 N56622 BQ004312
GeneLoc Exon Structure
|
Expression
for UBE2V1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBE2V1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTTGGTTTT
About this image
See UBE2V1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBE2V1
SOURCE GeneReport for Unigene cluster: Hs.420529
UniProtKB/Swiss-Prot: UB2V1_HUMAN, Q13404Tissue specificity: Highly expressed in thyroid, pancreas, spinal cord, lymph node, trachea, adrenal gland, bone marrowand pancreas. Detected at low levels in heart, breast, placenta, brain, liver, kidney, stomach and lung
SABiosciences Custom PCR Arrays for UBE2V1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2V1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat UBE2V1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2V1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2V1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2V1 |
Orthologs
for UBE2V1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBE2V1 gene from 8/23 species (see all 23) About this table
ENSEMBL Gene Tree for UBE2V1 (if available)
TreeFam Gene Tree for UBE2V1 (if available) |
Paralogs
for UBE2V1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBE2V1 gene
- TMEM1892 UBE2V22 TMEM189-UBE2V12
2 SIMAP similar genes for UBE2V1 using alignment to 2 protein entries: UB2V1_HUMAN (see all proteins):TMEM189 UBE2V2
UBE2V1 for paralogs About GeneDecksing
5/12 Pseudogenes.org Pseudogenes for UBE2V1 (see all 12)
PGOHUM00000234971 PGOHUM00000244081 PGOHUM00000244417 PGOHUM00000247427 PGOHUM00000240968
|
Genomic Variants
for UBE2V1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBE2V1 (48697661 - 48732496 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for UBE2V1
1 CNV: 5140 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2V1 |
|
Disorders
/ Diseases
for UBE2V1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBE2V1 for disorders About GeneDecksing
OMIM gene information: 602995
OMIM disorders: --
9  diseases for UBE2V1: About MalaCardscolon adenocarcinoma conjunctivitis pancreatic cancer adenocarcinoma
prostate cancer pancreatitis prostatitis thyroiditis
malaria
1 Novoseek disease relationship for UBE2V1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
12.1 |
3 |
10329586 (1), 9705497 (1) |
Export disorders for UBE2V1 gene to outside databases
|
Publications
for UBE2V1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBE2V1 gene, integrated from 9 sources (see all 62):
(articles sorted by number of sources associating them with UBE2V1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Role of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29- M6 intestinal mucosecretory cells. (PubMed id 9418904)1, 2, 3 Sancho E.... Thomson T.M. (1998)
- CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter. (PubMed id 9305758)1, 2, 3 Rothofsky M.L. and Lin S.L. (1997)
- The products of the yeast MMS2 and two human homologs (hMMS2 and CROC-1) define a structurally and functionally conserved Ubc-like protein family. (PubMed id 9705497)1, 2, 9 Xiao W.... Wei Y.-F. (1998)
- Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene. (PubMed id 11076860)1, 2, 9 Thomson T.M.... Guigo R. (2000)
- Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. (PubMed id 11057907)1, 2, 9 Deng L.... Chen Z.J. (2000)
- TRIM5 is an innate immune sensor for the retrovirus c apsid lattice. (PubMed id 21512573)1, 2 Pertel T....Luban J. (2011)
- Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. (PubMed id 16307917)1, 2 Zhang M....Pearl L.H. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
|
External Searches for UBE2V1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE2V1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBE2V1 gene
(According to HUGE)
About This Section
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Specialized Databases showing UBE2V1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for UBE2V1 gene:
Search GeneIP for patents involving UBE2V1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for UBE2V1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | OriGene Antibodies for UBE2V1 | | OriGene shRNA RFP for UBE2V1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE2V1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2V1 | | | OriGene Protein Over-expression Lysate for UBE2V1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBE2V1 | | OriGene 3'-UTR Clone for UBE2V1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2V1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2V1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for UBE2V1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBE2V1 | | OriGene Custom Protein Services for UBE2V1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE2V1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2V1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2V1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE2V1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2V1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2V1 |
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| | | | Search Tocris compounds for UBE2V1 |
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 | | | UBE2V1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2V1 |
|  |  |  |  | | | | ThermoFisher Antibodies for UBE2V1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2V1 |
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