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UBE2U Gene

protein-coding   GIFtS: 51
GCID: GC01P064669

Ubiquitin-Conjugating Enzyme E2U (Putative)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ubiquitin-Conjugating Enzyme E2U (Putative)1 2
Ubiquitin Carrier Protein U2 3
Ubiquitin-Protein Ligase U2 3
Ubiquitin-Conjugating Enzyme E2 U2
EC 6.3.2.193

External Ids:    HGNC: 285591   Entrez Gene: 1485812   Ensembl: ENSG000001774147   UniProtKB: Q5VVX93   

Export aliases for UBE2U gene to outside databases

Previous GC identifers: GC01P064382 GC01P062778


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for UBE2U Gene:
UBE2U (ubiquitin-conjugating enzyme E2U (putative)) is a protein-coding gene. Diseases associated with UBE2U include crohn's disease. GO annotations related to this gene include ubiquitin-protein ligase activity. An important paralog of this gene is UBE2B.

UniProtKB/Swiss-Prot: UBE2U_HUMAN, Q5VVX9
Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the UBE2U gene promoter:
         ER-alpha   Sox5   RREB-1   Pax-2   Nkx2-5   Ik-3   Evi-1   AREB6   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUBE2U promoter sequence
   Search Chromatin IP Primers for UBE2U

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat UBE2U


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.3   Ensembl cytogenetic band:  1p31.3   HGNC cytogenetic band: 1p31.3

UBE2U Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBE2U gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P064669:  view genomic region     (about GC identifiers)

Start:
64,669,310 bp from pter      End:
64,733,051 bp from pter
Size:
63,742 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: UBE2U_HUMAN, Q5VVX9 (See protein sequence)
Recommended Name: Ubiquitin-conjugating enzyme E2 U  
Size: 321 amino acids; 37741 Da
1 PDB 3D structure from and Proteopedia for UBE2U:
1YRV (3D)    
Secondary accessions: Q8N1D4
Alternative splicing: 2 isoforms:  Q5VVX9-1   Q5VVX9-2   

Explore the universe of human proteins at neXtProt for UBE2U: NX_Q5VVX9

Explore proteomics data for UBE2U at MOPED


See UBE2U Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_689702.1  
ENSEMBL proteins: 
 ENSP00000360117   ENSP00000360116   ENSP00000477356   ENSP00000476556  
Reactome Protein details: Q5VVX9

UBE2U Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for UBE2U

UBE2U Antibody Products:

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UBE2U Assay Products:

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Cloud-Clone Corp. CLIAs for UBE2U


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
UBE2: Ubiquitin-conjugating enzymes E2

3 InterPro protein domains:
 IPR023313 UBQ-conjugating_AS
 IPR000608 UBQ-conjugat_E2
 IPR016135 UBQ-conjugating_enzyme/RWD

Graphical View of Domain Structure for InterPro Entry Q5VVX9

ProtoNet protein and cluster: Q5VVX9

1 Blocks protein domain: IPB000608 Ubiquitin-conjugating enzymes

UniProtKB/Swiss-Prot: UBE2U_HUMAN, Q5VVX9
Similarity: Belongs to the ubiquitin-conjugating enzyme family


UBE2U for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: UBE2U_HUMAN, Q5VVX9
Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity)
Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine

     Enzyme Number (IUBMB): EC 6.3.2.191

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004842ubiquitin-protein ligase activity IEA--
GO:0005524ATP binding IEA--
GO:0016881acid-amino acid ligase activity ----
     
UBE2U for ontologies           About GeneDecksing


Phenotypes:
     2 GenomeRNAi human phenotypes for UBE2U:
 Increased cell number in G2M,   Synthetic lethal with Ras 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for UBE2U
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for UBE2U

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for UBE2U
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for UBE2U

miRNA
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1 qRT-PCR Assays for microRNA that regulate UBE2U:
hsa-miR-450b-5p
SwitchGear 3'UTR luciferase reporter plasmidUBE2U 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for UBE2U
Predesigned siRNA for gene silencing in human, mouse, rat UBE2U

Gene Editing
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GenScript: all cDNA clones in your preferred vector: UBE2U (NM_152489)
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Cell Line
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In Situ Assay
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol3
nucleus2
cytoskeleton1
peroxisome1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for UBE2U About                                                                                                See pathways by source

SuperPathContained pathways About
1Class I MHC mediated antigen processing and presentation
Class I MHC mediated antigen processing and presentation0.84
Adaptive Immune System0.41
Antigen processing- Ubiquitination and Proteasome degradation0.84
Ubiquitin mediated proteolysis0.35

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


1 Reactome Pathway for UBE2U
    Antigen processing: Ubiquitination & Proteasome degradation


1 Kegg Pathway  (Kegg details for UBE2U):
    Ubiquitin mediated proteolysis

UniProtKB/Swiss-Prot: UBE2U_HUMAN, Q5VVX9
Pathway: Protein modification; protein ubiquitination


UBE2U for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for UBE2U
Interactions:

    Search GeneGlobe Interaction Network for UBE2U

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for UBE2U (Q5VVX93 ENSP000003601164) via UniProtKB, MINT, STRING, and/or I2D (see all 237)

InteractantInteraction Details
GeneCardExternal ID(s)
ENSG00000224145Q9C0193, ENSP000003982244I2D: score=2 STRING: ENSP00000398224
ENSG00000235960Q9C0193, ENSP000004116834I2D: score=2 STRING: ENSP00000411683
ENSG00000137384Q9C0193I2D: score=2 
ENSG00000227147Q9C0193I2D: score=2 
ENSG00000233599Q9C0193I2D: score=2 
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for UBE2U

4 HMDB Compounds for UBE2U    About this table
CompoundSynonyms CAS #PubMed Ids
Adenosine monophosphate5'-AMP (see all 28)61-19-8--
Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for UBE2U gene: 
NM_152489.1  

Unigene Cluster for UBE2U:

Ubiquitin-conjugating enzyme E2U (putative)
Hs.388746  [show with all ESTs]
Unigene Representative Sequence: BC029895
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000371077 ENST00000371076(uc001dbn.1) ENST00000608020 ENST00000464349
ENST00000608956
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat UBE2U using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate UBE2U:
hsa-miR-450b-5p
SwitchGear 3'UTR luciferase reporter plasmidUBE2U 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for UBE2U
Predesigned siRNA for gene silencing in human, mouse, rat UBE2U
Clone
Products:
     
OriGene clones in human, mouse for UBE2U (see all 5)
OriGene ORF clones in mouse, rat for UBE2U
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: UBE2U (NM_152489)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for UBE2U
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2U
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for UBE2U
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat UBE2U
  QuantiTect SYBR Green Assays in human, mouse, rat UBE2U
  QuantiFast Probe-based Assays in human, mouse, rat UBE2U

Additional mRNA sequence: BC029895.1 

3 DOTS entries:

DT.100015008  DT.70100712  DT.70103714 

21 AceView cDNA sequences:

AI198955 AI538316 NM_152489 BQ022574 BC029895 AI208348 BU193579 AA626174 
AI478778 BI825812 AI377288 BX116499 BG773201 AW136185 AI655911 BI462751 
BG773116 AI765312 R20805 BU561173 R20919 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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UBE2U expression in normal human tissues (normalized intensities)      UBE2U embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGCTTCAGAG
UBE2U Expression
About this image


UBE2U expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 5) fully expand
 
 Brain (Nervous System)    fully expand to see all 4 entries
         Cerebral Cortex
 
 Testis (Reproductive System)
         Leydig Cells Testis Interstitium
 
 Trophoblast (Extraembryonic Tissues)
         Trophoblast Cells Trophoblast
 
 Ovary (Reproductive System)
         Oviduct
 
 Liver (Hepatobiliary System)
         Hepatocytes Liver Lobule
UBE2U Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

UBE2U Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.388746
    Custom PCR Arrays for UBE2U
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Products:
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2U

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for UBE2U gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Ube2u1 , 5 ubiquitin-conjugating enzyme E2U (putative)1, 5 73.3(n)1
57.08(a)1
  4 (45.72 cM)5
3815341  NM_001033773.41  NP_001028945.21 
 1004788495 
lizard
(Anolis carolinensis)
Reptilia UBE2U6
ubiquitin-conjugating enzyme E2U (putative)
41(a)
1 ↔ 1
4(98825482-98845164)
tropical clawed frog
(Xenopus tropicalis)
Amphibia ube2u1 ubiquitin-conjugating enzyme E2U (putative) 56.48(n)
48.7(a)
  101733423  XM_004913929.1  XP_004913986.1 
zebrafish
(Danio rerio)
Actinopterygii zgc:555126
zgc:55512
34(a)
many ↔ many
9(9024874-9028935) ENSDARG00000003017
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RAD66
Ubiquitin-conjugating enzyme (E2), involved in pos...
29(a)
1 → many
VII(393986-394504) YGL058W


ENSEMBL Gene Tree for UBE2U (if available)
TreeFam Gene Tree for UBE2U (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for UBE2U gene
UBE2B2  UBE2S2  UBE2A2  
14 SIMAP similar genes for UBE2U using alignment to 3 protein entries:     UBE2U_HUMAN (see all proteins):
UBE2C    HR6A    UBE2A    UBE2B    UBE2L6    UBE2G1
UBE2D1    UBE2D2    UBE2D3    UBE2D4    UBE2N    UBE2DNL
UBE2G2    UBE2I

UBE2U for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for UBE2U
PGOHUM00000246298


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for UBE2U (see all 825)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs29352061,2
C--64667621(+) ttcttC/Ttgcct 1 -- us2k11Minor allele frequency- T:0.00NA 2
rs1998276841,2
C--64667729(+) ATGTGC/GTTTGT 1 -- us2k10--------
rs344003021,2
C--64667951(+) TAAAT-/AAAT  
        
CAGAG
1 -- us2k10--------
rs49159501,2
C,A,H--64667955(+) taaaaA/Taaata 1 -- us2k1 tfbs32Minor allele frequency- T:0.00NA 4
rs120346401,2
C--64667959(+) ataaaA/Taaata 1 -- us2k1 tfbs31Minor allele frequency- T:0.00NA 2
rs49159511,2
C,F--64667963(+) ataaaA/Taaata 1 -- us2k1 tfbs32Minor allele frequency- T:0.00NA 4
rs1449022131,2
--64668002(+) ACACTC/TTCCTG 1 -- us2k10--------
rs118099541,2
C,F,H--64668005(+) CTCTCC/TTGTTT 1 -- us2k14Minor allele frequency- T:0.02NS NA 186
rs1913030931,2
--64668065(+) CTACTC/GTATAG 1 -- us2k10--------
rs1417404041,2
--64668304(+) ATGACC/TTACCC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for UBE2U (64669310 - 64733051 bp)

Structural Variations
     Database of Genomic Variants (DGV) 6 variations for UBE2U:    About this table    
Variant IDTypeSubtypePubMed ID
esv2749096CNV Deletion23290073
esv2749107CNV Deletion23290073
esv2749118CNV Deletion23290073
esv1385597CNV Deletion17803354
nsv871805CNV Loss21882294
dgv55e1CNV Complex17122850

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing UBE2U
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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1 disease for UBE2U:    About MalaCards
crohn's disease


UBE2U for disorders           About GeneDecksing

Genetic Association Database (GAD): UBE2U

Export disorders for UBE2U gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for UBE2U gene integrated from 10 sources:
(articles sorted by number of sources associating them with UBE2U)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  4. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)1 Markson G....Sanderson C.M. (Genome Res. 2009)
  5. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)1 van Wijk S.J....Timmers H.T. (Mol. Syst. Biol. 2009)
  6. Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. (PubMed id 18069675)9 Sakiyama T....Tsubouchi H. (Inflamm. Bowel Dis. 2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 148581 HGNC: 28559 AceView: MGC35130 Ensembl:ENSG00000177414 euGenes: HUgn148581
ECgene: UBE2U Kegg: 148581 H-InvDB: UBE2U

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for UBE2U Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for UBE2U gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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