UBE2S Gene
protein-coding GIFtS : 60
GCID: GC19 M055912
ubiquitin-conjugating enzyme E2S
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Aliasesfor UBE2S gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Ubiquitin-Conjugating Enzyme E2S 1 2 Ubiquitin-Protein Ligase S2 3 E2-EPF1 2 3 EC 6.3.2.193 8 E2EPF2 3 5 EPF52 5 Ubiquitin Carrier Protein S2 3 E2-EPF52 Ubiquitin-Conjugating Enzyme E2-24 KDa2 3 Ubiquitin-Conjugating Enzyme E2 S2 Ubiquitin-Conjugating Enzyme E2-EPF52 3 Ubiquitin-Conjugating Enzyme E2-24 KD2
Export aliases for UBE2S gene to outside databases Previous GC identifers: GC19M060604 GC19M052233
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Summariesfor UBE2S gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for UBE2S : This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: UBE2S_HUMAN, Q16763 Function : Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination
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Genomic Viewsfor UBE2S gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000019.9 NC_018930.1 NT_011109.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the UBE2S gene promoter: Egr-3 SRF RREB-1 SRF (504 AA) MEF-2 Egr-4 MEF-2A SEF-1 (1) aMEF-2 RSRFC4 Other transcription factors Search SABiosciences Chromatin IP Primers for UBE2S Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat UBE2S
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 19q13.43 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.43 UBE2S Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 19 GeneLoc Exon Structure
GeneLoc location for GC19M055912: view genomic region
(about GC identifiers )
Start:
55,912,650 bp from pter
End:
55,919,325 bp from pter
Size:
6,676 bases
Orientation:
minus strand
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Proteinsfor UBE2S gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: UBE2S_HUMAN, Q16763 (See
protein sequence )Recommended Name: Ubiquitin-conjugating enzyme E2 S Size : 222 amino acids; 23845 Da
Subunit : Component of the APC/C complex. Interacts with CDC20, FZR1/CDH1 and VHL
1 PDB 3D structure from and Proteopedia for UBE2S :1ZDN (3D)
 
Secondary accessions : Q9BTC1Explore the universe of human proteins at neXtProt for UBE2S: NX_Q16763 Post-translational modifications:
Autoubiquitinated by the APC/C complex during G1, leading to its degradation by the proteasome1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q16763 2 DME Specific Peptides for UBE2S (Q16763 ) UBE2S Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_055316.2 ENSEMBL proteins: ENSP00000264552 ENSP00000467409 ENSP00000466388 Reactome Protein details: Q16763 Human Recombinant Protein Products for UBE2S: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
UBE2S for ontologies About GeneDecksing UBE2S Antibody Products: Assay Products for UBE2S:
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Protein
Domains / Familiesfor UBE2S gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
UBE2S for domains About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q16763 ProtoNet protein and cluster: Q16763
1 Blocks protein family : IPB000608 Ubiquitin-conjugating enzymes UniProtKB/Swiss-Prot: UBE2S_HUMAN, Q16763 Similarity : Belongs to the ubiquitin-conjugating enzyme family
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Functionfor UBE2S gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: UBE2S_HUMAN, Q16763 Function : Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination Catalytic activity : ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine Enzyme Number (IUBMB): EC 6.3.2.19 1 2
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
UBE2S for ontologies About GeneDecksing Phenotypes: 3 GenomeRNAi human phenotypes for UBE2S :Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UBE2S (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UBE2S (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: UBE2S (NM_014501 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2S Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UBE2S
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Pathways & Interactionsfor UBE2S gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 Antigen processing: Ubiquitination & Proteasome degradation 2 Immune System 3 Protein Stability 4 Cell Cycle / Checkpoint Control
Pathway sources See GeneCards unified pathways Show all pathways 2
Cell Signaling Technology (CST) Pathways for UBE2S 5
Reactome Pathways for UBE2S 1
Kegg Pathway (Kegg details for UBE2S) :UniProtKB/Swiss-Prot: UBE2S_HUMAN, Q16763 Pathway : Protein modification; protein ubiquitination
UBE2S for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UBE2S STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/565 Interacting proteins for UBE2S (Q16763 2 , 3 ENSP00000264552 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 565 )
About this table Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11 ): About this table
UBE2S for ontologies About GeneDecksing
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Drugs & Compoundsfor UBE2S gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for UBE2S 4 HMDB Compounds for UBE2S About this table Search CenterWatch for drugs/clinical trials and news about UBE2S
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Transcriptsfor UBE2S gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for UBE2S gene: NM_014501.2 Unigene Cluster for UBE2S:
Ubiquitin-conjugating enzyme E2S Hs.396393 [show with all ESTs ] Unigene Representative Sequence: BM479313 4 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000264552 (uc002qkx.1 ) ENST00000587845 ENST00000589978 ENST00000592570 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UBE2S (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UBE2S (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: UBE2S (NM_014501 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2S Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UBE2S
Additional cDNA sequence: AB062397.1 BC004236.2 BC007554.1 BC065364.1 BC066948.1 M91670.1
21 DOTS entries : DT.99948312 DT.100793466
DT.451729 DT.121503213 DT.100793470 DT.120974316 DT.121503215 DT.100793463 DT.91762377 DT.95269991 DT.100793465 DT.121004353 DT.436623 DT.92412032 DT.99991873 DT.120974360 DT.121503180 DT.121503189 DT.121503229 DT.91653365 DT.91762375 24/385 AceView cDNA sequences (see all 385 ):
BG114410 BQ018306 BQ926180 M91670 BG179097 BE262243 BC065364 BE781600 BG250687 BU623599 BU739658 BE253593 BE791805 BM782899 BM794482 BG283238 NM_014501 BI060905 BE793231 BC047644 AW104280 BE269633 CR594048 BF035772 GeneLoc Exon Structure
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Expression for UBE2S gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section UBE2S expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: CTGGCGAGCGAbout this image UBE2S expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Gut Tube Ventral Foregut Endoderm Gut Tube Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See UBE2S Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for UBE2S SOURCE GeneReport for Unigene cluster: Hs.396393 SABiosciences Expression via Pathway-Focused PCR Array including UBE2S : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for UBE2SBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat UBE2S QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat UBE2S QIAGEN QuantiFast Probe-based Assays in human , mouse , rat UBE2S
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Orthologsfor UBE2S gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBE2S gene from 6/28 species (see all 28 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
lizard (Anolis carolinensis)
Reptilia
UBE2S6
--
84(a)
1 ↔ 1
GL343279.1(1389848-1392064)
African clawed frog (Xenopus laevis)
Amphibia
MGC528312
hypothetical protein MGC52831
73.52(n)
 
BC041263.1
zebrafish (Danio rerio)
Actinopterygii
Dr.179702
Transcribed sequence with moderate similarity to protein more
76.39(n)
 
AL722209.1
fruit fly (Drosophila melanogaster)
Insecta
CG81881
CG8188
66.17(n) 63.5(a)
 
32751 NM_001038763.1 NP_001033852.1
thale cress (Arabidopsis thaliana)
eudicotyledons
UBC221
ubiquitin-conjugating enzyme E2 22
56.27(n) 58.6(a)
 
830390 NM_001085061.1 NP_001078530.1
rice (Oryza sativa)
Liliopsida
Os06g06607001
hypothetical protein
55.44(n) 56.99(a)
 
4341740 NM_001064806.1 NP_001058271.1
ENSEMBL Gene Tree for UBE2S (if available)TreeFam Gene Tree for UBE2S (if available)
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Paralogsfor UBE2S gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for UBE2S gene UBE2B 2 UBE2O 2 BIRC6 2 UBE2Z 2 UBE2A 2 18/24 SIMAP similar genes for UBE2S using alignment to 4 protein entries: UBE2S_HUMAN (see all proteins )
(see all similar genes ):UBE2H UBE2N UBE2D3 UBE2D4 UBE2D2 UBE2C UBE2I UBE2K UBE2D1 UBE2B UBE2NL UBE2E3 UBE2G1 UBE2M UBE2E1 UBE2A UBE2E2 UBE2T
UBE2S for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for UBE2S PGOHUM00000237265
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Genomic Variantsfor UBE2S gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 19 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for UBE2S (55912650 - 55919325 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for UBE2S: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing UBE2S
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Disorders
/ Diseasesfor UBE2S gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
UBE2S for disorders About GeneDecksing
OMIM gene information: 610309
OMIM disorders : --10 diseases for UBE2S : About MalaCards pemphigus foliaceus esophageal squamous cell carcinoma liddle syndrome squamous cell carcinoma pemphigus angelman syndrome renal cell carcinoma parkinson's disease esophagitis carcinoma Export disorders for UBE2S gene to outside databases
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Publicationsfor UBE2S gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for UBE2S gene, integrated from 9 sources (see all 37 ): (articles sorted by number of sources associating them with UBE2S) Utopia : connect your pdf to the dynamic world of online information
cDNA cloning of a novel human ubiquitin carrier protein. An antigenic domain specifically recognized by endemic pemphigus foliaceus autoantibodies is encoded in a secondary reading frame of this human epidermal transcript. (PubMed id 1379239) 1 , 2 , 3 Liu Z.... Giudice G.J. (1992) Lys11-linked ubiquitin chains adopt compact conformat ions and are preferentially hydrolyzed by the deubiquitinase Cezanne. (PubMed id 20622874) 1 , 2 Bremm A....Komander D. (2010) UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit. (PubMed id 19820702) 1 , 2 Garnett M.J.... Venkitaraman A.R. (2009) Identification of a physiological E2 module for the human anaphase- promoting complex. (PubMed id 19822757) 1 , 2 Williamson A....Rape M. (2009) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) A census of human soluble protein complexes. (PubMed id 22939629) 1 Havugimana P.C....Emili A. (2012) The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1. (PubMed id 22529100) 1 Huang N.J.... Kornbluth S. (2012) Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724) 1 Udeshi N.D....Carr S.A. (2012) Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931) 1 Oshikawa K....Nakayama K.I. (2012) E1-E2 interactions in ubiquitin and Nedd8 ligation pat hways. (PubMed id 22069333) 1 Tokgoz Z....Haas A.L. (2012)
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Specialized Databases showing UBE2S gene (According to PharmGKB ,
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About This Section Patent Information for UBE2S gene: Search GeneIP for patents involving UBE2S GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor UBE2S gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
OriGene Antibodies for UBE2S OriGene shRNA RFP for UBE2S OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for UBE2S OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for UBE2S OriGene Protein Over-expression Lysate for UBE2S Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for UBE2S OriGene 3'-UTR Clone for UBE2S OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for UBE2S OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for UBE2S Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for UBE2S OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for UBE2S OriGene Custom Protein Services for UBE2S OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE2S QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing UBE2S QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat UBE2S QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat UBE2S QIAGEN QuantiFast Probe-based Assays in human , mouse , rat UBE2S QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat UBE2S
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UBE2S Proteins, Antibodies, CLIAs, and ELISAs
ThermoFisher Antibody for UBE2S
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat UBE2S
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