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Aliases for UBE2Q2L Gene

Aliases for UBE2Q2L Gene

  • Ubiquitin Conjugating Enzyme E2 Q2 Like 2 3 5
  • Ubiquitin-Conjugating Enzyme E2Q Family Member 2-Like 2

External Ids for UBE2Q2L Gene

Previous GeneCards Identifiers for UBE2Q2L Gene

  • GC15P084843

Summaries for UBE2Q2L Gene

GeneCards Summary for UBE2Q2L Gene

UBE2Q2L (Ubiquitin Conjugating Enzyme E2 Q2 Like) is a Protein Coding gene. An important paralog of this gene is ENSG00000279287.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBE2Q2L Gene

Genomics for UBE2Q2L Gene

Regulatory Elements for UBE2Q2L Gene

Enhancers for UBE2Q2L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15F084714 1.2 ENCODE 11.1 +543.5 543472 3.4 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 GOLGA6L5P NMB UBE2Q2P1 GOLGA6L4 GOLGA6L3 WDR73 DNM1P51 SEC11A LINC00933 CSPG4P12
GH15F084979 1.2 ENCODE 10.4 +809.3 809309 4.7 HDGF PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 GOLGA6L4 GOLGA6L5P UBE2Q2P1 LINC00933 ZNF592 CSPG4P12 GOLGA6L3 WDR73 CSPG4P11 ENSG00000259544
GH15F084816 1.5 FANTOM5 Ensembl ENCODE 4.2 +648.9 648918 9.6 ELF3 HDGF HDAC1 PKNOX1 ARNT ARID4B DMAP1 ZSCAN9 ZBTB40 RAD21 WDR73 ZNF592 ALPK3 NMB GOLGA6L5P ENSG00000200991 SLC28A1 GOLGA6L3 SEC11A ENSG00000259683
GH15F084833 1.3 Ensembl ENCODE 4.2 +665.5 665467 10.4 HDGF ATF1 PKNOX1 ARID4B SIN3A GLI4 FEZF1 ZNF2 YY1 GLIS2 NMB ALPK3 WDR73 ZNF592 GOLGA6L5P GOLGA6L4 LINC00933 CSPG4P11 SCAND2P ENSG00000259683
GH15F083970 0.5 ENCODE 6 -201.9 -201930 0.7 ZNF316 ZNF362 MAFK RNU6-401P UBE2Q2L RN7SL331P ENSG00000274128 LOC642677
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around UBE2Q2L on UCSC Golden Path with GeneCards custom track

Promoters for UBE2Q2L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001797613 910 2400 PKNOX1 ESRRA ZIC2 THRB RAD21 YY1 RARA CTBP1 GLIS2 GATA3

Genomic Location for UBE2Q2L Gene

Chromosome:
15
Start:
84,172,490 bp from pter
End:
84,182,234 bp from pter
Size:
9,745 bases
Orientation:
Plus strand

Genomic View for UBE2Q2L Gene

Genes around UBE2Q2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBE2Q2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBE2Q2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2Q2L Gene

Proteins for UBE2Q2L Gene

  • Protein details for UBE2Q2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H0YL09-U2Q2L_HUMAN
    Recommended name:
    Putative ubiquitin-conjugating enzyme E2Q2-like protein
    Protein Accession:
    H0YL09

    Protein attributes for UBE2Q2L Gene

    Size:
    131 amino acids
    Molecular mass:
    14853 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2Q2L Gene

Post-translational modifications for UBE2Q2L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UBE2Q2L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBE2Q2L Gene

Domains & Families for UBE2Q2L Gene

Protein Domains for UBE2Q2L Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

H0YL09

UniProtKB/Swiss-Prot:

U2Q2L_HUMAN :
  • Belongs to the ubiquitin-conjugating enzyme family.
Family:
  • Belongs to the ubiquitin-conjugating enzyme family.
genes like me logo Genes that share domains with UBE2Q2L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for UBE2Q2L Gene

Function for UBE2Q2L Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBE2Q2L Gene

Localization for UBE2Q2L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for UBE2Q2L Gene

Pathways & Interactions for UBE2Q2L Gene

SuperPathways for UBE2Q2L Gene

No Data Available

Interacting Proteins for UBE2Q2L Gene

Gene Ontology (GO) - Biological Process for UBE2Q2L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for UBE2Q2L Gene

Transcripts for UBE2Q2L Gene

mRNA/cDNA for UBE2Q2L Gene

(3) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2Q2L Gene

No ASD Table

Relevant External Links for UBE2Q2L Gene

GeneLoc Exon Structure for
UBE2Q2L
ECgene alternative splicing isoforms for
UBE2Q2L

Expression for UBE2Q2L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UBE2Q2L Gene

mRNA differential expression in normal tissues according to GTEx for UBE2Q2L Gene

This gene is overexpressed in Testis (x6.7).

NURSA nuclear receptor signaling pathways regulating expression of UBE2Q2L Gene:

UBE2Q2L
genes like me logo Genes that share expression patterns with UBE2Q2L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for UBE2Q2L Gene

Orthologs for UBE2Q2L Gene

Evolution for UBE2Q2L Gene

ENSEMBL:
Gene Tree for UBE2Q2L (if available)
TreeFam:
Gene Tree for UBE2Q2L (if available)

No data available for Orthologs for UBE2Q2L Gene

Paralogs for UBE2Q2L Gene

Paralogs for UBE2Q2L Gene

Pseudogenes.org Pseudogenes for UBE2Q2L Gene

genes like me logo Genes that share paralogs with UBE2Q2L: view

Variants for UBE2Q2L Gene

Sequence variations from dbSNP and Humsavar for UBE2Q2L Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1061613 -- 84,182,151(+) GTTAA(A/G)TGATA intron-variant, utr-variant-3-prime
rs111709212 -- 84,170,865(+) GATTT(A/G)CCAAA nc-transcript-variant, upstream-variant-2KB
rs111883629 -- 84,180,303(+) CCAGC(C/T)TGGGC intron-variant
rs112460502 -- 84,180,199(+) TGGCA(C/G)GTGCC intron-variant
rs112900811 -- 84,184,938(+) CCTGA(G/T)TTTCA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for UBE2Q2L Gene

Variant ID Type Subtype PubMed ID
dgv2638n100 CNV gain 25217958
dgv2639n100 CNV loss 25217958
dgv2640n100 CNV gain 25217958
dgv2641n100 CNV loss 25217958
dgv2642n100 CNV gain+loss 25217958
dgv752e212 CNV loss 25503493
esv2760048 CNV gain+loss 17122850
esv29092 CNV gain+loss 19812545
esv3569809 CNV gain 25503493
nsv1038297 CNV gain+loss 25217958
nsv1070290 CNV deletion 25765185
nsv1126405 CNV deletion 24896259
nsv1141271 CNV duplication 24896259
nsv428310 CNV gain+loss 18775914
nsv518289 CNV loss 19592680
nsv827418 CNV loss 20364138
nsv833075 CNV gain 17160897
nsv833076 CNV loss 17160897
nsv9290 CNV gain+loss 18304495
nsv976960 CNV duplication 23825009
nsv977803 CNV duplication 23825009

Variation tolerance for UBE2Q2L Gene

Gene Damage Index Score: 0.38; 8.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for UBE2Q2L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UBE2Q2L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBE2Q2L Gene

Disorders for UBE2Q2L Gene

Relevant External Links for UBE2Q2L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UBE2Q2L

No disorders were found for UBE2Q2L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBE2Q2L Gene

Publications for UBE2Q2L Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4 64

Products for UBE2Q2L Gene

Sources for UBE2Q2L Gene

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