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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

UBE2Q1 Gene

protein-coding   GIFtS: 53
GCID: GC01M154521

ubiquitin-conjugating enzyme E2Q family member 1

(Previous name: ubiquitin-conjugating enzyme E2Q (putative) )
(Previous symbol: UBE2Q)
 Explore 1 disease affiliated with
UBE2Q1 via our new
 Human Malady Compendium 
Biological research products
for UBE2Q1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ubiquitin-Conjugating Enzyme E2Q Family Member 11 2     PRO30941
UBE2Q1 2 3     Ubiquitin-Conjugating Enzyme E2Q (Putative)1
NICE-51 2     GTAP2
Protein NICE-52 3     Galactosyl Transferase-Associated Protein2
Ubiquitin Carrier Protein Q12 3     Ubiquitin-Conjugating Enzyme E2 Q12
Ubiquitin-Protein Ligase Q12 3     Ubiquitin-Conjugating Enzyme E2Q (Putative) 12
EC 6.3.2.193 8     NICE53

External Ids:    HGNC: 156981   Entrez Gene: 555852   Ensembl: ENSG000001607147   UniProtKB: Q7Z7E83   

Export aliases for UBE2Q1 gene to outside databases

Previous GC identifers: GC01M151336 GC01M152787 GC01M125884


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for UBE2Q1:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived
proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes
(E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2
ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. (provided by
RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: UB2Q1_HUMAN, Q7Z7E8
Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the UBE2Q1 gene promoter:
         Egr-3   AhR   AP-1   HOXA3   NRSF form 1   CUTL1   NRSF form 2   Arnt   GATA-2   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidUBE2Q1 promoter sequence
   Search SABiosciences Chromatin IP Primers for UBE2Q1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2Q1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q22

UBE2Q1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
UBE2Q1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M154521:  view genomic region     (about GC identifiers)

Start:
154,521,051 bp from pter      End:
154,531,504 bp from pter
Size:
10,454 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UB2Q1_HUMAN, Q7Z7E8 (See protein sequence)
Recommended Name: Ubiquitin-conjugating enzyme E2 Q1  
Size: 422 amino acids; 46127 Da
Sequence caution: Sequence=AAF71141.1; Type=Erroneous initiation; Sequence=AAH61583.1; Type=Erroneous initiation;
Sequence=AAH87836.1; Type=Erroneous initiation; Sequence=AAI07058.1; Type=Erroneous initiation; Sequence=BAB71173.1;
Type=Erroneous initiation; Sequence=CAB65097.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for UBE2Q1:
2QGX (3D)    
Secondary accessions: B4DF92 Q3B841 Q5I0X2 Q6IS04 Q6P7P2 Q96MV4 Q9BVX5 Q9UGL6
Alternative splicing: 2 isoforms:  Q7Z7E8-1   Q7Z7E8-2   

Explore the universe of human proteins at neXtProt for UBE2Q1: NX_Q7Z7E8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q7Z7E8

  • 4/9 DME Specific Peptides for UBE2Q1 (Q7Z7E8) (see all 9)
     HCNITESYP  DLQILKEKEG  LNGAVSGSVQA  EDLDHYEMKEEEP 

    UBE2Q1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060052.3  
    ENSEMBL proteins: 
     ENSP00000292211  
    Reactome Protein details: Q7Z7E8
    Human Recombinant Protein Products: 
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    Novus Biologicals UBE2Q1 Protein
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    Uscn Proteins for UBE2Q1


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    Uscn ELISAs and CLIAs for UBE2Q1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    UBE2Q1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR016135 UBQ-conjugating_enzyme/RWD
     IPR000608 UBQ-conjugat_E2

    Graphical View of Domain Structure for InterPro Entry Q7Z7E8

    ProtoNet protein and cluster: Q7Z7E8

    1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes

    UniProtKB/Swiss-Prot: UB2Q1_HUMAN, Q7Z7E8
    Similarity: Belongs to the ubiquitin-conjugating enzyme family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: UB2Q1_HUMAN, Q7Z7E8
    Function: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity)
    Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine

    Enzyme Number (IUBMB): EC 6.3.2.191 2

    miRNA
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    miRTarBase miRNAs that target UBE2Q1:
    hsa-mir-338-3p (MIRT003038)

    OriGene 3'-UTR Clone: UBE2Q1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UBE2Q1
    8/83 QIAGEN miScript miRNA Assays for microRNAs that regulate UBE2Q1 (see all 83):
    hsa-miR-323-3p hsa-miR-607 hsa-miR-1321 hsa-miR-15a hsa-miR-485-3p hsa-miR-3142 hsa-miR-3613-3p hsa-miR-3116
    SwitchGear 3'UTR luciferase reporter plasmidUBE2Q1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE2Q1 (see all 6)
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE2Q1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2Q1

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity IEA--
    GO:0005515protein binding IPI16275660
    GO:0005524ATP binding IEA--


    UBE2Q1 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Antigen processing: Ubiquitination & Proteasome degradation
    Antigen processing: Ubiquitination & Proteasome degradation1.00
    Polyubiquitination of substrate0.75
    Class I MHC mediated antigen processing & presentation0.83
    Ubiquitin mediated proteolysis0.36
    2Immune System
    Immune System1.00
    Adaptive Immune System0.59

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for UBE2Q1
        Antigen processing: Ubiquitination & Proteasome degradation
    Polyubiquitination of substrate
    Adaptive Immune System
    Class I MHC mediated antigen processing & presentation
    Immune System


    1         Kegg Pathway  (Kegg details for UBE2Q1):
        Ubiquitin mediated proteolysis

    UniProtKB/Swiss-Prot: UB2Q1_HUMAN, Q7Z7E8
    Pathway: Protein modification; protein ubiquitination


    UBE2Q1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBE2Q1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/565 Interacting proteins for UBE2Q1 (Q7Z7E81, 2, 3 ENSP000002922114) via UniProtKB, MINT, STRING, and/or I2D (see all 565)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    STUB1Q9UNE71, 3, ENSP000002195484EBI-1783287,EBI-357085 I2D: score=2 STRING: ENSP00000219548
    IRF2BPLQ9H1B73, ENSP000002386474I2D: score=2 STRING: ENSP00000238647
    RNF26Q9BY783, ENSP000003124394I2D: score=2 STRING: ENSP00000312439
    RNF7Q9UBF63, ENSP000002734804I2D: score=2 STRING: ENSP00000273480
    EXOSC7Q150243, ENSP000002655644I2D: score=1 STRING: ENSP00000265564
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for UBE2Q1
    Search CenterWatch for drugs/clinical trials and news about UBE2Q1 / UB2Q1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for UBE2Q1 gene: 
    NM_017582.6  

    Unigene Cluster for UBE2Q1:

    Ubiquitin-conjugating enzyme E2Q family member 1
    Hs.607928  [show with all ESTs]
    Unigene Representative Sequence: AY112698
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000292211(uc001fff.1) ENST00000467683 ENST00000491572 ENST00000476612
    ENST00000483639 ENST00000474181 ENST00000497453

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat UBE2Q1
    8/83 QIAGEN miScript miRNA Assays for microRNAs that regulate UBE2Q1 (see all 83):
    hsa-miR-323-3p hsa-miR-607 hsa-miR-1321 hsa-miR-15a hsa-miR-485-3p hsa-miR-3142 hsa-miR-3613-3p hsa-miR-3116
    SwitchGear 3'UTR luciferase reporter plasmidUBE2Q1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE2Q1 (see all 6)
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    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: UBE2Q1 (NM_017582)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2Q1 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2Q1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2Q1

    Additional cDNA sequence: 

    AF116721.1 AJ243666.1 AK056388.1 AK293986.1 AY112698.1 AY948200.1 BC000848.1 BC009286.2 
    BC015316.1 BC061583.1 BC070158.1 BC087836.1 BC107057.2 BC148185.2 CR457219.1 

    12 DOTS entries:

    DT.445463  DT.100787963  DT.95177258  DT.95177259  DT.95177260  DT.97848196  DT.86845719  DT.100731176 
    DT.100787949  DT.121368402  DT.121609964  DT.91741799 

    24/341 AceView cDNA sequences (see all 341):

    AI347988 BC009286 BM969062 CR597936 AI199704 AA641342 AI675917 BG029803 
    BE677811 CA439626 BM468040 NM_017582 BC015316 BM698867 AI811270 N39701 
    CA436833 CA412811 AA311601 BG680591 BX419858 AI434631 AI190688 BG478026 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2Q1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12
    SP1:                                                                                    
    SP2:                                                                                    
    SP3:                                                                    -     -         


    ECgene alternative splicing isoforms for UBE2Q1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    UBE2Q1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TACACTGCTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See UBE2Q1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for UBE2Q1

    SOURCE GeneReport for Unigene cluster: Hs.607928

    UniProtKB/Swiss-Prot: UB2Q1_HUMAN, Q7Z7E8
    Tissue specificity: Widely expressed

        SABiosciences Expression via Pathway-Focused PCR Array including UBE2Q1: 
              Ubiquitination (Ubiquitylation) Pathway in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2Q1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for UBE2Q1 gene from 3/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves LOC1008585641 ubiquitin-conjugating enzyme E2 Q1-like 85.52(n)
    94.89(a)
      100858564  XM_003643367.1  XP_003643415.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG29246
    --
    52(a)
    1 → many
    X(2159024-2164789)
    worm
    (Caenorhabditis elegans)
    Secernentea ubc-256
    UBiquitin Conjugating enzyme family member (ubc-25...
    46(a)
    1 → many
    I(10562957-10564903)


    ENSEMBL Gene Tree for UBE2Q1 (if available)
    TreeFam Gene Tree for UBE2Q1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for UBE2Q1 gene
    UBE2Q22  UBE2QL12  
    3 SIMAP similar genes for UBE2Q1 using alignment to 2 protein entries:     UB2Q1_HUMAN (see all proteins):
    GTAP    UBE2Q2    UBE2QL1

    UBE2Q1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/166 NCBI SNPs in UBE2Q1 are shown (see all 166    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1412867001,2
    --154520592(+) TAACCA/TATGAG 3 -- ds5001 ut310--------
    rs1886302431,2
    --154520667(+) ACTGCC/TCTGCC 3 -- ds50010--------
    rs1462724721,2
    --154520860(+) TGTTTA/CTTTTT 3 -- ds50010--------
    rs1810392751,2
    --154520997(+) CCTCTA/GTGTCA 3 -- ds50010--------
    rs1394146971,2
    --154521055(+) AACTAC/TTTAAA 3 -- ut31 ds50010--------
    rs802722151,2
    C,F,--154521259(+) GTCCCG/ATCTTT 1 -- ut311Minor allele frequency- A:0.03WA 118
    rs412699151,2
    C,F,--154521584(+) GTAGGT/ACCTAA 1 -- ut317Minor allele frequency- A:0.18WA NA CSA EA 366
    rs1836523871,2
    --154521831(+) CCTTGG/TGGGAG 1 -- ut310--------
    rs1463093191,2
    --154521885(+) AGCTAC/GGTCTG 1 -- ut310--------
    rs1883166571,2
    --154522006(+) ACAGCA/GAAGAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for UBE2Q1 (154521051 - 154531504 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for UBE2Q1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2Q1
    DNA2.0 Custom Variant and Variant Library Synthesis for UBE2Q1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    UBE2Q1 for disorders           About GeneDecksing

    1 disease for UBE2Q1:    About MalaCards
    choroiditis


    Export disorders for UBE2Q1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for UBE2Q1 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with UBE2Q1)
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    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Identification of human epidermal differentiation complex (EDC)- encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. (PubMed id 11230159)1, 2 Marenholz I....Mischke D. (2001)
    5. Expression of the novel human gene, UBE2Q1, in breast tumors. (PubMed id 22167327)1 Seghatoleslam A....Owji A.A. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Frameshift mutations of ubiquitination-related genes H ERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability. (PubMed id 22124266)1 Yoo N.J....Lee S.H. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. (PubMed id 20682791)1 Gorbea C.... Rechsteiner M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55585 HGNC: 15698 AceView: UBE2Q Ensembl:ENSG00000160714 euGenes: HUgn55585
    ECgene: UBE2Q1 Kegg: 55585 H-InvDB: UBE2Q1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for UBE2Q1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for UBE2Q1 gene:
    Search GeneIP for patents involving UBE2Q1

    GeneCards and IP:
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