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Aliases &
Descriptions
for UBE2NL
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| | | Descriptions |
|---|
| ubiquitin-conjugating enzyme E2N-like 2 |
|
| |
Search outside databases for aliases for UBE2NL genePrevious GC identifers: GC0XP141661 GC0XP142692 |
Summaries
for UBE2NL(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location
for UBE2NL
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the UBE2NL gene 
Entrez Gene cytogenetic band: Xq27.3 Ensembl cytogenetic band: Xq27.3 HGNC cytogenetic band: Xq27.3UBE2NL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP142794:
(about GC identifiers)
Start:
|
142,794,839 bp from pter |
End:
|
142,796,028 bp from pter |
Size:
|
1,190 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011786.15
| Proteins
for UBE2NL
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: UE2NL_HUMAN, Q5JXB2 (See
protein sequence)Recommended Name: Putative ubiquitin-conjugating enzyme E2 N-like Size: 153 amino acids; 17377 Da
Caution: Could be the product of a pseudogene. The potential active site Cys residue in position 88
is replaced by a SerREFSEQ proteins: NP_001013007.1
ENSEMBL proteins: ENSP00000359525
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
Antibodies for UBE2NL:
Assays for UBE2NL: | Protein
Domains/
Families
for UBE2NL(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q5JXB2
ProtoNet protein and cluster: Q5JXB2 1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes
UniProtKB/Swiss-Prot: UE2NL_HUMAN, Q5JXB2Similarity: Belongs to the ubiquitin-conjugating enzyme family | Gene Function
for UBE2NL
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001012989
 Applied Biosystems Silencer® siRNAs for UBE2NL
 Sigma-Aldrich siRNA and siRNA Panels for UBE2NL
Sigma-Aldrich shRNA for UBE2NL
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001012989
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001012989
untagged cDNA clone in CMV expression vector: NM_001012989
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001012989
1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004842 | ubiquitin-protein ligase activity |
IEA | -- |
About this table | Pathways & Interactions
for UBE2NL
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
3 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process |
IEA | -- | | GO:0043687 | post-translational protein modification |
IEA | -- | | GO:0051246 | regulation of protein metabolic process |
IEA | -- |
About this table
|
Drugs & Compounds
for UBE2NL(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for UBE2NL
|
Transcripts
for UBE2NL(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001012989
Sigma-Aldrich siRNA and siRNA Panels for UBE2NL
Sigma-Aldrich shRNA for UBE2NL
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001012989 REFSEQ mRNAs for UBE2NL gene: NM_001012989.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001012989
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001012989
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001012989
untagged cDNA clone in CMV expression vector: NM_001012989
3 DOTS entries: DT.100855012 DT.100767810 DT.453669 1 AceView cDNA sequence:BV191502
 highest scoring ESTs for UBE2NL:NM_001012989 CN275855 CN275859 DA492651 DA937232 DW424639 T98324 AA323166 BP339429 CR986681 Unigene Cluster for UBE2NL: Ubiquitin-conjugating enzyme E2N-like Hs.585177 [show with all ESTs]Unigene Representative Sequence: NM_001012989
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000370494
|
Expression
for UBE2NL
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| UBE2NL expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for UBE2NL
1 / 2 4 probe-sets matching UBE2NL gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: AGCAGAGGCT
SOURCE GeneReport for Unigene cluster: Hs.585177
|
Orthologs
for UBE2NL
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for UBE2NL gene from 2 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
dog
(Canis familiaris) |
UBE2NL1 |
-- |
ubiquitin-conjugating enzyme E2N-like |
93.42(n)
90.13(a) |
610206 XM_848637.1 XP_853730.1 |
mouse
(Mus musculus) |
Ube2nl1, 5 |
75
|
ubiquitin-conjugating enzyme E2N-like1, 5 |
90.79(n)1
86.18(a)1 |
6209341 XM_885442.31 XP_890535.11 |
About this table Species with no ortholog for UBE2NL
ENSEMBL Gene Tree for UBE2NL | Paralogs
for UBE2NL(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for UBE2NL gene
- UBE2K2 UBE2T2 UBE2N2
|
SNPs/Variants
for UBE2NL(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for UBE2NL (up to first 250kb)
|
Disorders & Mutations
for UBE2NL
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for UBE2NL(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for UBE2NL (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 2 PubMed articles for UBE2NL gene: |
Search for UBE2NL
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE2NL
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing UBE2NL
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBE2NL(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for UBE2NL(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for UBE2NL:
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