Aliases for UBE2NL Gene
External Ids for UBE2NL Gene
Previous GeneCards Identifiers for UBE2NL Gene
This gene is intronless and encodes a member of the ubiquitin-conjugating enzyme family. The protein product is 91% identical to ubiquitin-conjugating enzyme E2N, a multi-exon gene product. This locus represents a polymorphic pseudogene, where some individuals contain an allele that can encode a full-length protein, while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence. [provided by RefSeq, Jun 2014]
GeneCards Summary for UBE2NL Gene
UBE2NL (Ubiquitin Conjugating Enzyme E2 N Like (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with UBE2NL include Migraine With Or Without Aura 1. Among its related pathways are Ubiquitin mediated proteolysis and protein ubiquitylation. GO annotations related to this gene include ubiquitin protein ligase binding and ubiquitin-like protein transferase activity. An important paralog of this gene is UBE2N.