UBE2M Gene
protein-coding GIFtS: 66
GCID: GC19M059067
|
|
ubiquitin-conjugating enzyme E2M(Previous names: ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12),...)
| |
Aliases
for UBE2M gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin-Conjugating Enzyme E2M1 2 | | NEDD8-Conjugating Enzyme Ubc122 | | UBC121 2 3 | | Ubiquitin Carrier Protein M2 | | HUbc121 | | Ubiquitin-Protein Ligase M2 | | Ubiquitin-Conjugating Enzyme E2M (UBC12 Homolog, Yeast)1 2 | | Yeast UBC12 Homolog2 | | NEDD8 Carrier Protein2 3 | | EC 6.3.2.-3 | | NEDD8 Protein Ligase2 3 | | Ubiquitin-Conjugating Enzyme E2 M3 | | Ubiquitin-Conjugating Enzyme E2M (Homologous To Yeast UBC12)1 | | EC 6.3.28 | | UBC-RS22 | | |
Export aliases for UBE2M gene to outside databasesPrevious GC identifers: GC19M059965 GC19M059521 GC19M063742 GC19M063758 |
Summaries
for UBE2M gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UBE2M:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, orE1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of theE2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which canbe conjugated to cellular proteins, such as Cdc53/culin. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: UBC12_HUMAN, P61081Function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachmentto other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that theRBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cellproliferation
Gene Wiki entry for UBE2M
|
Genomic Views
for UBE2M gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBE2M gene promoter:
AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBE2M
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2M |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.43 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.43UBE2M Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M059067: view genomic region
(about GC identifiers)
Start:
|
59,067,079 bp from pter |
End:
|
59,070,343 bp from pter |
Size:
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3,265 bases |
Orientation:
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minus strand |
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Proteins
for UBE2M gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UBC12_HUMAN, P61081 (See
protein sequence)Recommended Name: NEDD8-conjugating enzyme Ubc12 Size: 183 amino acids; 20900 Da
Subunit: Interacts with UBA3, DCUN1D1 and RBX1
6 PDB 3D structures from  and Proteopedia  for UBE2M:1TT5 (3D)
1Y8X (3D)
2NVU (3D)
3TDU (3D)
3TDZ (3D)
4GAO (3D)
Secondary accessions: O76069 Q8VC50Explore the universe of human proteins at neXtProt for UBE2M: NX_P61081
Post-translational modifications:
The acetylation of Met-1 is cotranslational, and not regulatory. The N-acetylmethionine increases affinity for DCUN1D1by about 2 orders of magnitude and is crucial for NEDD8 transfer to cullins1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P61081
4 DME Specific Peptides for UBE2M (P61081)
UBE2M Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003960.1
ENSEMBL proteins: ENSP00000253023 Reactome Protein details: P61081
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
UBE2M for ontologies About GeneDecksing
UBE2M Antibody Products:
Assay Products for UBE2M: |
Protein
Domains /
Families
for UBE2M gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBE2M for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P61081ProtoNet protein and cluster: P61081 1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes
UniProtKB/Swiss-Prot: UBC12_HUMAN, P61081Domain: Both the N-terminal docking peptide and the catalytic core domain must bind the UBA3-NAE1 complexsimultaneously for optimal transfer of NEDD8Similarity: Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily |
Function
for UBE2M gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: UBC12_HUMAN, P61081Function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachmentto other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that theRBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cellproliferationCatalytic activity: ATP + NEDD8 + protein lysine = AMP + diphosphate + protein N-NEDD8yllysineEnzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2M (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2M
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UBE2M (NM_003969) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2M | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2M |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2M |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
UBE2M for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for UBE2M:
|
Pathways & Interactions
for UBE2M gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | | | 3 | Protein Stability | | | 4 | Ubiquitin-Proteasome Dependent Proteolysis | | | 5 | Remodeling of Adherens Junctions | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for UBE2M
1 
Cell Signaling Technology (CST) Pathway for UBE2M
5 
Reactome Pathways for UBE2M
1 
Kegg Pathway (Kegg details for UBE2M):
UniProtKB/Swiss-Prot: UBC12_HUMAN, P61081Pathway: Protein modification; protein neddylation
UBE2M for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for UBE2M
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/860 Interacting proteins for UBE2M (P610811, 2, 3 ENSP000002530234) via UniProtKB, MINT, STRING, and/or I2D (see all 860)
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
UBE2M for ontologies About GeneDecksing
|
Drugs & Compounds
for UBE2M gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBE2M
4 HMDB Compounds for UBE2M About this table
Search CenterWatch for drugs/clinical trials and news about UBE2M / UBC12
|
Transcripts
for UBE2M gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBE2M gene: NM_003969.3 Unigene Cluster for UBE2M: Ubiquitin-conjugating enzyme E2M Hs.406068 [show with all ESTs]Unigene Representative Sequence: BM4235091 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000253023(uc002qtl.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2M (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2M
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UBE2M (NM_003969) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2M | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2M |
Additional cDNA sequence: AB012191.1 BC058924.1 BT006754.1 15 DOTS entries: DT.100797337 DT.118760 DT.100797334 DT.95094085 DT.100797341 DT.100797332 DT.121473486 DT.121473585 DT.95114897 DT.100797343 DT.95094086 DT.97854659 DT.100797331 DT.121473483 DT.97869739 24/250 AceView cDNA sequences (see all 250): CR599501 BE257314 BQ934496 AA512976 CR614452 BI063316 AI141340 CF128617 BC058924 CR602537 CR600769 AB012191 BM833180 BM710465 CR625272 F30409 CB267928 BM700562 CR623679 NM_003969 BM453243 AA588183 BP432687 CR604136
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2M About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UBE2M
|
Expression
for UBE2M gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBE2M expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGATTAAGGT
About this image
See UBE2M Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBE2M
SOURCE GeneReport for Unigene cluster: Hs.406068
SABiosciences Expression via Pathway-Focused PCR Array including UBE2M:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2M
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UBE2M | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2M | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2M | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2M |
Orthologs
for UBE2M gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBE2M gene from 8/32 species (see all 32) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ube2m1 , 5 |
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)5
ubiquitin-conjugating enzyme E2M1 |
94.35(n)1
100(a)1 |
|
7 (7.73 cM)5
221921 NM_145578.31 NP_663553.11
130352385 |
chicken
(Gallus gallus) |
Aves |
LOC1008586411 |
NEDD8-conjugating enzyme Ubc12-like |
83.76(n)
91.03(a) |
|
100858641 XM_003643841.1 XP_003643889.1 |
lizard
(Anolis carolinensis) |
Reptilia |
UBE2M6 |
-- |
98(a) |
1 ↔ 1 |
GL343253.1(119455-130809) |
African clawed frog
(Xenopus laevis) |
Amphibia |
480591772 |
-- |
81.46(n) |
|
48059177 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb58e052 |
Transcribed sequence with moderate similarity to protein more |
81.07(n) |
|
CA469653.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG73751 , 3 |
ubiquitin conjugating enzyme3
CG73751 |
75(a)3
73.56(n)1
76.54(a)1 |
|
66B123
389161 NM_139930.11 NP_648187.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G186001 |
ubiquitin-conjugating enzyme E2 M |
59.89(n)
63.19(a) |
|
816375 NM_127416.3 NP_565440.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.146562 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
70.79(n) |
|
AK066484.1 |
ENSEMBL Gene Tree for UBE2M (if available)
TreeFam Gene Tree for UBE2M (if available) |
Paralogs
for UBE2M gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBE2M gene
- ENSG000002589842 UBE2F2
18 SIMAP similar genes for UBE2M using alignment to 3 protein entries: UBC12_HUMAN (see all proteins):HR6A UBE2D2 UBE2D4 UBE2D3 UBE2B UBE2K
UBE2A UBE2D1 UBE2F UBE2E2 UBE2E3 UBE2I
UBE2N UBE2E1 UBE2L6 UBE2C UBE2S UBE2L3
UBE2M for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for UBE2M
PGOHUM00000248853
|
Genomic Variants
for UBE2M gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBE2M (59067079 - 59070343 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for UBE2M
3 CNVs: 50240 50238 50239 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2M |
|
Disorders
/ Diseases
for UBE2M gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBE2M for disorders About GeneDecksing
OMIM gene information: 603173
OMIM disorders: --
2  diseases for UBE2M: About MalaCardsmalaria neuronitis
Export disorders for UBE2M gene to outside databases
|
Publications
for UBE2M gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBE2M gene, integrated from 9 sources (see all 58):
(articles sorted by number of sources associating them with UBE2M) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A new NEDD8-ligating system for cullin-4A. (PubMed id 9694792)1, 2, 3 Osaka F.... Kato S. (1998)
- A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo. (PubMed id 10828074)1, 2, 9 Wada H.... Kamitani T. (2000)
- N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. (PubMed id 21940857)1, 2 Scott D.C.... Schulman B.A. (2011)
- E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. (PubMed id 19250909)1, 2 Huang D.T....Schulman B.A. (2009)
- Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1. (PubMed id 15694336)1, 2 Huang D.T....Schulman B.A. (2005)
- A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. (PubMed id 15361859)1, 2 Huang D.T.... Schulman B.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway. (PubMed id 10207026)1, 2 Gong L. and Yeh E.T.H. (1999)
- The mechanism of poly-NEDD8 chain formation in vitro. (PubMed id 19245792)1, 9 Ohki Y....Chiba T. (2009)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
|
External Searches for UBE2M gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE2M gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBE2M gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBE2M gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBE2M | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBE2M gene:
Search GeneIP for patents involving UBE2M
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for UBE2M gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for UBE2M | | OriGene shRNA RFP for UBE2M | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE2M | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2M | | | OriGene Protein Over-expression Lysate for UBE2M | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBE2M | | OriGene 3'-UTR Clone for UBE2M | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2M | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2M | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBE2M | | OriGene Custom Protein Services for UBE2M | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE2M | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2M | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2M | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE2M | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2M | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2M |
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| | Antibodies & Assays for UBE2M |
| | | | Search Tocris compounds for UBE2M |
| |  |  |  |  | | | | | | Recombinant Protein for UBE2M |
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 | | | UBE2M Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2M |
|  |  |  | | | | ThermoFisher Antibodies for UBE2M |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2M |
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