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UBE2J1 Gene

protein-coding GIFtS: 56

GC06M090093

ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
CGI-76 ^¹, ²
EC 6.3.2.19 ^³
HSPC153 ^¹, ²
HSPC205 ^²
HSU93243 ^²
HSUBC6e ^³
MGC12555 ^²
NCUBE1 ^¹, ², ³
OTTHUMP00000016852 ^²
Ubc6p ^²

Descriptions
Non-canonical ubiquitin-conjugating enzyme 1 ^³
Yeast ubiquitin-conjugating enzyme UBC6 homolog E ^³
non-canonical ubquitin conjugating enzyme 1 ^²
ubiquitin-conjugating enzyme E2, J1 ^²
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) ^²

External Ids
HGNC: 17598¹
Entrez Gene: 51465²
UniProtKB: Q9Y385³
Ensembl: ENSG00000198833⁷

Search outside databases for aliases for UBE2J1 gene

Previous GC identifers: GC06M090003 GC06M090032 GC06M090031

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for UBE2J1:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting

abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes

of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and

ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating

enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may

contribute to quality control ER-associated degradation by the ubiquitin-proteasome system.

[provided by RefSeq]

UniProtKB/Swiss-Prot: UB2J1_HUMAN, Q9Y385

Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in

the selective degradation of misfolded membrane proteins from the endoplasmic reticulum

Gene Wiki entry for UBE2J1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the UBE2J1 gene

Entrez Gene cytogenetic band: 6q15 Ensembl cytogenetic band: 6q15 HGNC cytogenetic band: 6q16.1

UBE2J1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M090093: (about GC identifiers)

Start:	90,093,063 bp from pter
End:	90,119,338 bp from pter
Size:	26,276 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000006.10 NT_007299.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: UB2J1_HUMAN, Q9Y385 (See protein sequence)

Recommended Name: Ubiquitin-conjugating enzyme E2 J1

Size: 318 amino acids; 35199 Da

Subcellular location: Endoplasmic reticulum membrane; Single-pass type IV membrane protein

Sequence caution: Sequence=AAF36125.1; Type=Frameshift; Positions=119;

Secondary accessions: A8K3F9 Q5W0N4 Q9BZ32 Q9NQL3 Q9NY66 Q9P011 Q9P0S0 Q9UF10

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_057105.2

ENSEMBL proteins:

ENSP00000354684

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (UBC6e)
	Human Recombinant Proteins from Abnova (UBE2J1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for UBE2J1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for UBE2J1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (UBC6e), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (UBE2J1)
	Novus Biologicals Antibodies for UBE2J1

Assays for UBE2J1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q9Y385

ProtoNet protein and cluster: Q9Y385

1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes

UniProtKB/Swiss-Prot: UB2J1_HUMAN, Q9Y385

Similarity: Belongs to the ubiquitin-conjugating enzyme family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE2J1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE2J1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_016336

Applied Biosystems Silencer® siRNAs for UBE2J1

Sigma-Aldrich siRNA and siRNA Panels for UBE2J1

Sigma-Aldrich shRNA Panels and shRNA for UBE2J1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_016021
Myc/DDK tagged cDNA clone in CMV expression vector: NM_016021
untagged cDNA clones in CMV expression vector (see all 2): NM_016021

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_016021

UniProtKB/Swiss-Prot: UB2J1_HUMAN, Q9Y385

Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in

the selective degradation of misfolded membrane proteins from the endoplasmic reticulum

Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein

N-ubiquityllysine

Enzyme Number (IUBMB): EC 6.3.2.19

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004842	ubiquitin-protein ligase activity	IEA	--
GO:0016874	ligase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for UBE2J1 (Your Favorite Gene powered by Ingenuity)

Protein Ubiquitination Pathway
Hypoxia Signaling in the Cardiovascular System

GeneDecks UBE2J1 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: UB2J1_HUMAN, Q9Y385

Pathway: Protein modification; protein ubiquitination

5 Interacting proteins for UBE2J1 (ENSP00000354684³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DERL1	ENSP00000259512³	STRING (score=.881)
HSPA8	ENSP00000227378³	STRING (score=.843)
STUB1	ENSP00000219548³	STRING (score=.836)
CFTR	ENSP00000003084³	STRING (score=.827)
PARK2	ENSP00000355865³	STRING (score=.713)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0019941	modification-dependent protein catabolic process	IEA	--
GO:0043687	post-translational protein modification	IEA	--
GO:0051246	regulation of protein metabolic process	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for UBE2J1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE2J1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE2J1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_016336

Sigma-Aldrich siRNA and siRNA Panels for UBE2J1

Sigma-Aldrich shRNA Panels and shRNA for UBE2J1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_016021

REFSEQ mRNAs for UBE2J1 gene:

NM_016021.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_016021

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_016021
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_016021
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_016021

Additional cDNA sequence:

AB075487.1 AF151039.1 AF151834.1 AF161502.1 AJ245898.1 AJ420479.1 AJ420522.1 AJ420578.1

AJ420600.1 AK223464.1 AK290574.1 AK300629.1 BC013973.1 CR593056.1 CR608832.1 CR618158.1

U93243.1

13 DOTS entries:

DT.452520 DT.91754919 DT.91754932 DT.92035712 DT.100726380 DT.100645848 DT.100645843 DT.91754923

DT.87001128 DT.95224761 DT.101976909 DT.121383951 DT.95141421

24/349 AceView cDNA sequences (see all 349 ):

AW118565 AW117721 BM984150 AA165621 BM712541 AA553859 AA622355 AA435533

CB997305 BU507628 AI338294 AA676862 W68181 AL525571 CA397036 AA705068

AW296841 BX645216 BX482869 BU509302 BQ009872 CA941012 BU688929 AL538922

highest scoring ESTs for UBE2J1:

AA018130 AA044667 AA156816 AA211896 AA371039 AA478628 AA491236 AA574142 AA614686 AA631316

Unigene Cluster for UBE2J1:

Ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)

Hs.163776 [show with all ESTs]

Unigene Representative Sequence: NM_016021

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2J1

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	·	6c	^	7a	·	7b	^	8a	·	8b	·	8c	·	8d
SP1:													-						-		-				-
SP2:													-
SP3:
SP4:																			-		-
SP5:																									-

About this scheme

ECgene alternative splicing isoforms for UBE2J1

1 Ensembl transcript including schematic representation:

ENST00000361333

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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UBE2J1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for UBE2J1

¹ / ² / ³

14 probe-sets matching UBE2J1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
57780_at²^{, 3}	U95-C	1	1.00	1.00	0.64	0.73	N57554	0.80	1.00	0.91	1
57081_at²^{, 3}	U95-B	1	1.00	1.00	0.76	1.13	AA044667	0.80	1.00	0.91	1
39039_s_at²^{, 3}	U95-A	1	1.00	1.00	0.93	1.22	AI557497	0.60	1.00	0.82	1
39040_at²^{, 3}	U95-A	2	1.00	0.97	0.84	0.93	W28360	0.80	1.00	0.91	1
217826_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_016021	0.60	1.00	0.82	1
217824_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AW500009	0.40	1.00	0.76	1
222435_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AF161502	0.80	1.00	0.91	1
217823_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL562528	0.40	1.00	0.76	1
217825_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF151039	0.60	1.00	0.82	1
217826_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
217824_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
222435_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
217823_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
217825_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks UBE2J1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
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CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.163776
Expression variation in blood from EXPOLDB for UBE2J1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for UBE2J1 gene from 5/13 species (see all 13 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	UBE2J1¹	--	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, more	92.19(n) 94.39(a)	474993 XM_532230.2 XP_532230.2
chimpanzee (Pan troglodytes)	UBE2J1¹	--	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, more	99.69(n) 99.69(a)	462883 XM_518636.2 XP_518636.2
cow (Bos taurus)	UBE2J1¹	--	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, more	93.19(n) 95.6(a)	539754 XM_866344.2 XP_871437.2
rat (Rattus norvegicus)	Ube2j1¹	--	ubiquitin-conjugating enzyme E2, J1	88.68(n) 93.28(a)	297961 XM_216362.4 XP_216362.3
mouse (Mus musculus)	Ube2j1^{1, 5}	4⁵	ubiquitin-conjugating enzyme E2, J1^{1, 5}	88.16(n)¹ 92.45(a)¹	56228¹ NM_019586.3¹ NP_062532.2¹ AI848527⁵ AJ245899⁵ (see all 19)

About this table Species with no ortholog for UBE2J1

ENSEMBL Gene Tree for UBE2J1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for UBE2J1 gene

UBE2J2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/126 NCBI SNPs in UBE2J1 are shown (see all 126 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 64)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs9048^1,2	A,C,F,H,O	90094300(-)	`ACCGAC/TGGTAG`	1	--	ut3¹ ese³		10	MN EU EA WA	1210
	rs6931561^1,2	A,C,F,H	90095675(+)	`AGTTTT/CGCTTT`	1	--	ut3¹		12	EU EA WA NS NA	668
	rs9344925^1,2	A,C,F,H	90093702(+)	`AAATGT/GCATGA`	1	--	ut3¹ ese³		15	EU EA WA NA	1400
	rs17798549^1,2	C,F,H	90096063(+)	`CCCAAT/GGCAGA`	1	--	ut3¹ ese³		11	NA EU EA WA	972
	rs10502^1,2	C,F,H	90096389(+)	`CTGGAC/GTCCGT`	1	L/V	mis¹ ese³		20	EA NS MN NA EU WA	2803
	rs13215418^1,2	C,F,H	90093230(+)	`AAATGC/TATTAA`	1	--	ut3¹ ese³		20	EU EA WA NA	1818
	rs6552^1,2	A,F	90094687(+)	`AATTTT/GCCTTT`	1	--	ut3¹		2	MN	372
	rs8099^1,2	H	90108835(-)	`TGATGG/TAGGAG`	1	G/V	mis¹ ese³		5	MN EU EA WA	590
	rs12200375^1,2	H	90092738(+)	`GCTGAG/AGTCTG`	1	--	ng5¹		4	EU EA WA	410
--	rs16881705^1,2	F	90096095(+)	`TCACAG/TCTCAT`	1	--	ut3¹		1	MN	184

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HapMap Linkage Disequilibrium images for UBE2J1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/20 PubMed articles for UBE2J1 gene (see all 20 ):

Identification of a family of non-canonical ubiquitin-conjugating enzymes structurally related to yeast UBC6. (PubMed id 10708578)^{1, 2, 3, 4} Lester D.H.... Houston B. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{3, 4} Mungall A.J.... Beck S. (2003)
A role for mammalian Ubc6 homologues in ER-associated protein degradation. (PubMed id 12082160)^{3, 4} Lenk U....Sommer T. (2002)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{3, 4} Zhang Q.H....Chen Z. (2000)
Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)^{3, 4} Lai C.H....Lin W. (2000)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS Spectra. (PubMed id 17924679)⁴ Yu L.-R.... Veenstra T.D. (2007)
Human homologs of Ubc6p ubiquitin-conjugating enzyme and phosphorylation of HsUbc6e in response to endoplasmic reticulum stress. (PubMed id 16720581)³ Oh R.S....Rommens J.M. (2006)
TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination. (PubMed id 15861135)³ Wu C.J....Ashwell J.D. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 51465	HGNC: 17598	AceView: UBE2J1	Ensembl:ENSG00000198833	euGenes: HUgn51465
ECgene: UBE2J1	H-InvDB: UBE2J1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for UBE2J1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for UBE2J1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for UBE2J1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for UBE2J1		Antibodies for UBE2J1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for UBE2J1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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UBE2J1 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for UBE2J1

Summaries
for UBE2J1

Genomic Location
for UBE2J1

Proteins
for UBE2J1

Protein Domains/
Families
for UBE2J1

Gene Function
for UBE2J1

Pathways & Interactions
for UBE2J1

Drugs & Compounds
for UBE2J1

Transcripts
for UBE2J1

Expression
for UBE2J1

Orthologs
for UBE2J1

Paralogs
for UBE2J1

SNPs/Variants
for UBE2J1

Disorders & Mutations
for UBE2J1

Medical News
for UBE2J1

Publications
for UBE2J1

Search for UBE2J1

Genome Databases showing UBE2J1

Other Databases showing UBE2J1

Specialized Databases showing UBE2J1

Licensable Technologies
for UBE2J1

Services
for UBE2J1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

UBE2J1 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor UBE2J1

Summariesfor UBE2J1

Genomic Locationfor UBE2J1

Proteinsfor UBE2J1

Protein Domains/Familiesfor UBE2J1

Gene Functionfor UBE2J1

Pathways & Interactionsfor UBE2J1

Drugs & Compoundsfor UBE2J1

Transcriptsfor UBE2J1

Expression for UBE2J1

Orthologsfor UBE2J1

Paralogsfor UBE2J1

SNPs/Variantsfor UBE2J1

Disorders & Mutationsfor UBE2J1

Medical Newsfor UBE2J1

Publicationsfor UBE2J1

Search for UBE2J1

Genome Databases showing UBE2J1

Other Databases showing UBE2J1

Specialized Databases showing UBE2J1

Licensable Technologiesfor UBE2J1

Servicesfor UBE2J1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for UBE2J1

Summaries
for UBE2J1

Genomic Location
for UBE2J1

Proteins
for UBE2J1

Protein Domains/
Families
for UBE2J1

Gene Function
for UBE2J1

Pathways & Interactions
for UBE2J1

Drugs & Compounds
for UBE2J1

Transcripts
for UBE2J1

Expression
for UBE2J1

Orthologs
for UBE2J1

Paralogs
for UBE2J1

SNPs/Variants
for UBE2J1

Disorders & Mutations
for UBE2J1

Medical News
for UBE2J1

Publications
for UBE2J1

Licensable Technologies
for UBE2J1

Services
for UBE2J1