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UBE2G2 Gene

protein-coding GIFtS: 63

GC21M045013

ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
(Previous name: ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase, and/or ⁹Nature:405,311-319 and CroW21)
About This Section

Aliases
EC 6.3.2.19 ^³
UBC7 ^¹, ², ⁵

Descriptions
Ubiquitin carrier protein G2 ^², ³
Ubiquitin-protein ligase G2 ^², ³
human ubiquitin conjugating enzyme G2 ⁹
ubiquitin conjugating enzyme 7 ^²
ubiquitin conjugating enzyme G2 ^²
ubiquitin-conjugating enzyme E2G 2 ^²
ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) ^²
ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7) ^¹, ²

External Ids
HGNC: 12483¹
Entrez Gene: 7327²
UniProtKB: P60604³
Ensembl: ENSG00000184787⁷

Search outside databases for aliases for UBE2G2 gene

Previous GC identifers: GC21M042698 GC21M045045

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for UBE2G2:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting

abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes

of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and

ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating

enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This

gene is ubiquitously expressed, with high expression seen in adult muscle. Two alternatively

spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by

RefSeq]

UniProtKB/Swiss-Prot: UB2G2_HUMAN, P60604

Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Involved in endoplasmic

reticulum-associated degradation (ERAD)

Gene Wiki entry for UBE2G2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.3 Ensembl cytogenetic band: 21q22.3 HGNC cytogenetic band: 21q22.3
Nature(405: 311-319) cytogenetic band: 21q22.3

UBE2G2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 21 GeneLoc Exon Structure

(about GC identifiers)

GC21M045013:	GeneLoc	Nature:405,311-319
Start:	45,013,383 bp from pter	31,698,366 bp from centromere
End:	45,046,166 bp from pter	31,731,118 bp from centromere
Size:	32,784 bases	32,753 bases
Orientation:	minus strand	minus strand

RefSeq DNA sequence:

NC_000021.7 NT_011515.11

Whole chromosome sequencing:
cDNA sequence:	AF032456
genomic clones:	P225L15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: UB2G2_HUMAN, P60604 (See protein sequence)

Recommended Name: Ubiquitin-conjugating enzyme E2 G2

Size: 165 amino acids; 18566 Da

PDB structures from and Proteopedia :

2CYX (3D)

Secondary accessions: P56554

REFSEQ proteins (2 alternative transcripts):

NP_003334.2 NP_872630.1

ENSEMBL proteins:

ENSP00000381001 ENSP00000338348 ENSP00000331384 ENSP00000381000

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant UBE2G2 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Ube2G2)
	Human Recombinant Proteins from Abnova (UBE2G2)

OriGene Purified Recombinant Human Proteins (see all 2): UBE2G2

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	IDA	16780588

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Antibodies for UBE2G2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of UBE2G2
	Sigma-Aldrich Antibodies for UBE2G2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Ube2G2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (UBE2G2)
	Novus Biologicals Antibodies for UBE2G2

Assays for UBE2G2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P60604

ProtoNet protein and cluster: P60604

1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes

UniProtKB/Swiss-Prot: UB2G2_HUMAN, P60604

Similarity: Belongs to the ubiquitin-conjugating enzyme family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE2G2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE2G2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_003343

Applied Biosystems Silencer® siRNAs for UBE2G2

Sigma-Aldrich siRNA and siRNA Panels for UBE2G2

Sigma-Aldrich shRNA Panels and shRNA for UBE2G2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003343
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003343
untagged cDNA clones in CMV expression vector (see all 2): NM_003343

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003343

UniProtKB/Swiss-Prot: UB2G2_HUMAN, P60604

Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Involved in endoplasmic

reticulum-associated degradation (ERAD)

Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein

N-ubiquityllysine

Enzyme Number (IUBMB): EC 6.3.2.19

Genatlas biochemistry entry for UBE2G2:

ubiquitin conjugating enzyme,homolog to yeast UBC7,with two transcript,ubiquitously expressed

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004842	ubiquitin-protein ligase activity	IEA	--
GO:0005515	protein binding	IPI	17681147
GO:0016874	ligase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for UBE2G2 (Your Favorite Gene powered by Ingenuity)

Protein Ubiquitination Pathway
Hypoxia Signaling in the Cardiovascular System

GeneDecks UBE2G2 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: UB2G2_HUMAN, P60604

Pathway: Protein modification; protein ubiquitination

5/7 Interacting proteins for UBE2G2 (ENSP00000338348³ P60604¹) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AMFR	Q9UKV5¹	STRING (score=.976) EBI-1051028, EBI-1046367
ALG11	Q2TAA5¹	EBI-1051028, EBI-1048799
AUP1	Q9Y679¹	EBI-1051028, EBI-1058701
CORO1A	P31146¹	EBI-1051028, EBI-1046676
MALT1	Q9UDY8¹	EBI-1051028, EBI-1047372

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006511	ubiquitin-dependent protein catabolic process	TAS	9693041
GO:0043687	post-translational protein modification	IEA	--
GO:0051246	regulation of protein metabolic process	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for UBE2G2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (UBE2G2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (UBE2G2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_003343

Sigma-Aldrich siRNA and siRNA Panels for UBE2G2

Sigma-Aldrich shRNA Panels and shRNA for UBE2G2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003343 NM_182688

REFSEQ mRNAs for UBE2G2 gene (2 alternative transcripts):

NM_003343.4 NM_182688.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003343 NM_182688

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003343
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003343
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_003343

Additional cDNA sequence: BC017241.2

19 DOTS entries:

DT.121132559 DT.454521 DT.92449943 DT.100840051 DT.40116400 DT.424690 DT.438750 DT.100030109

DT.121132538 DT.95226324 DT.100778705 DT.100778709 DT.121132556 DT.121132557 DT.92449941 DT.95226297

DT.100695636 DT.100778710 DT.92449945

24/379 AceView cDNA sequences (see all 379 ):

AA700565 BM312498 AA659503 CA436766 CK822080 CD367486 BP341530 BU191548

CK430987 AW731802 AA311312 AA443634 BQ218385 CA748881 AW188157 BC011569

BU630302 BM480344 BU782522 AW068356 AA449337 BU184932 CR593095 BM353079

highest scoring ESTs for UBE2G2:

AA100375 AF032456 AI215057 AL038702 AL530398 AL598640 AL603453 AU098906 AW672742 BC001738

Unigene Clusters for UBE2G2:

Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)

Hs.529420 [show with all ESTs], Hs.701398 [show with all ESTs]

Unigene Representative Sequences: AK122700, BC017241

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2G2 (see all 8 )

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	^	7a	·	7b	^	8a	·	8b	·	8c
SP1:													-		-		-		-		-		-
SP2:													-		-						-		-
SP3:													-
SP4:					-		-		-				-		-		-		-		-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for UBE2G2

4 Ensembl transcripts including schematic representations:

ENST00000397904 ENST00000345496 ENST00000330942 ENST00000397903

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

UBE2G2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for UBE2G2

¹ / ² / ³

9 probe-sets matching UBE2G2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32236_at²^{, 3}	U95-A	1	1.00	1.00	0.66	1.42	AF032456	0.80	1.00	0.91	1
76889_at²^{, 3}	U95-E	1	1.00	1.00	0.83	0.59	AI215057	0.80	1.00	0.91	1
232755_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AL355686	0.60	1.00	0.82	1
209042_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BC001738	0.80	1.00	0.91	1
209041_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BG395660	0.60	1.00	0.82	1
232755_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209042_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1557053_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209041_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene clusters: Hs.529420 Hs.701398
Expression variation in blood from EXPOLDB for UBE2G2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for UBE2G2 gene from 5/20 species (see all 20 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	UBE2G2¹	--	ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)	90.29(n) 95.36(a)	611581 XM_535603.2 XP_535603.2
chimpanzee (Pan troglodytes)	UBE2G2¹	--	ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)	99.39(n) 100(a)	474042 XM_531493.2 XP_531493.1
cow (Bos taurus)	UBE2G2¹	--	ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)	91.52(n) 99.39(a)	614471 NM_001076328.1 NP_001069796.1
rat (Rattus norvegicus)	Ube2g2¹	--	ubiquitin-conjugating enzyme E2G 2	89.49(n) 100(a)	294331 XM_215371.4 XP_215371.3
mouse (Mus musculus)	Ube2g2^{1, 5}	10 (41.60 cM)⁵	ubiquitin-conjugating enzyme E2G 2^{1, 5}	89.49(n)¹ 100(a)¹	22213¹ NM_019803.3¹ NP_062777.2¹ AF296657⁵ AI839191⁵ (see all 21)

About this table Species with no ortholog for UBE2G2

ENSEMBL Gene Tree for UBE2G2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for UBE2G2 gene

UBE2G1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/209 NCBI SNPs in UBE2G2 are shown (see all 209 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 111)

AB	SNP ID	Valid	Chr 21 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs235352^1,2	A,C,F,H,O	45013256(-)	`TGGCAC/TGTTTT`	2	--	ng5¹		12	NA EU EA WA	1000
	rs2838677^1,2	A,C,F,H,O	45014195(+)	`CTACTG/ATATGC`	2	--	ut3¹ ese³		9	NA EU EA WA	654
	rs1060564^1,2	A,C,F,H,O	45015602(-)	`AACCAC/TGGCAT`	2	--	ut3¹ ese³		9	NA MN EU EA WA	736
	rs11569^1,2	A,C,F,H	45015698(-)	`GGCGCA/GCACAC`	2	--	ut3¹		6	MN EU EA WA	770
	rs2838691^1,2	C,F,H,O	45047999(+)	`CACTGC/TAACAT`	2	--	ng3¹		7	NA EU EA	441
	rs84188^1,2	A,C,F,O	45046275(+)	`CTACGG/ATTCTC`	2	--	ng3¹		8	EA NA	1962
--	rs2838676^1,2	C,F,H,O	45013714(+)	`GCCCTG/CCGTTC`	2	--	ut3¹ ese³		8	NA EU EA WA	545
--	rs760431^1,2	A,C,F,H	45014079(+)	`AAGCCA/CGGCGT`	2	--	ut3¹		5	MN EU EA WA	600
	rs4818975^1,2	A,C,F,H	45015684(+)	`AGCTGC/ATTGGC`	2	--	ut3¹ ese³		8	MN NA EU EA WA	678
	rs8103^1,2	A,C,F,H	45013658(-)	`ACCTAT/AGTTGT`	2	--	ut3¹		12	NA MN EU EA	1006

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HapMap Linkage Disequilibrium images for UBE2G2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603124

1 PharmGKB disease relationship for UBE2G2 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/27 PubMed articles for UBE2G2 gene (see all 27 ):

Identification, expression, and chromosomal localization of ubiquitin conjugating enzyme 7 (UBE2G2), a human homologue of the Saccharomyces cerevisiae UBC7 gene. (PubMed id 9693041)^{1, 2, 3, 4} Katsanis N. and Fisher E.M.C. (1998)
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7). (PubMed id 16582478)^{1, 3, 4} Arai R.... Yokoyama S. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 21. (PubMed id 10830953)^{3, 4} Hattori M....Yaspo M.L. (2000)
Assignment1 of the ubiquitin conjugating enzyme gene, UBE2G2, to human chromosome band 21q22.3 by in situ hybridization. (PubMed id 9925943)^{2, 3} Rose S.A....Robinson P.A. (1998)
Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase. (PubMed id 17681147)³ Cao J....Song B.L. (2007)
Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)³ Ewing R.M....Figeys D. (2007)
The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site. (PubMed id 16407162)³ Chen B....Weissman A.M. (2006)
Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. (PubMed id 16780588)³ Hu Y.H....Janitz M. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 7327	HGNC: 12483	AceView: UBE2G2	Ensembl:ENSG00000184787	euGenes: HUgn7327
ECgene: UBE2G2	H-InvDB: UBE2G2

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for UBE2G2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for UBE2G2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for UBE2G2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for UBE2G2		Antibodies for UBE2G2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for UBE2G2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	shRNA in GFP-retroviral vector

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UBE2G2 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for UBE2G2

Summaries
for UBE2G2

Genomic Location
for UBE2G2

Proteins
for UBE2G2

Protein Domains/
Families
for UBE2G2

Gene Function
for UBE2G2

Pathways & Interactions
for UBE2G2

Drugs & Compounds
for UBE2G2

Transcripts
for UBE2G2

Expression
for UBE2G2

Orthologs
for UBE2G2

Paralogs
for UBE2G2

SNPs/Variants
for UBE2G2

Disorders & Mutations
for UBE2G2

Medical News
for UBE2G2

Publications
for UBE2G2

Search for UBE2G2

Genome Databases showing UBE2G2

Other Databases showing UBE2G2

Specialized Databases showing UBE2G2

Licensable Technologies
for UBE2G2

Services
for UBE2G2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

UBE2G2 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor UBE2G2

Summariesfor UBE2G2

Genomic Locationfor UBE2G2

Proteinsfor UBE2G2

Protein Domains/Familiesfor UBE2G2

Gene Functionfor UBE2G2

Pathways & Interactionsfor UBE2G2

Drugs & Compoundsfor UBE2G2

Transcriptsfor UBE2G2

Expression for UBE2G2

Orthologsfor UBE2G2

Paralogsfor UBE2G2

SNPs/Variantsfor UBE2G2

Disorders & Mutationsfor UBE2G2

Medical Newsfor UBE2G2

Publicationsfor UBE2G2

Search for UBE2G2

Genome Databases showing UBE2G2

Other Databases showing UBE2G2

Specialized Databases showing UBE2G2

Licensable Technologiesfor UBE2G2

Servicesfor UBE2G2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for UBE2G2

Summaries
for UBE2G2

Genomic Location
for UBE2G2

Proteins
for UBE2G2

Protein Domains/
Families
for UBE2G2

Gene Function
for UBE2G2

Pathways & Interactions
for UBE2G2

Drugs & Compounds
for UBE2G2

Transcripts
for UBE2G2

Expression
for UBE2G2

Orthologs
for UBE2G2

Paralogs
for UBE2G2

SNPs/Variants
for UBE2G2

Disorders & Mutations
for UBE2G2

Medical News
for UBE2G2

Publications
for UBE2G2

Licensable Technologies
for UBE2G2

Services
for UBE2G2