UBE2G1 Gene
protein-coding GIFtS: 64
GCID: GC17M004120
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ubiquitin-conjugating enzyme E2G 1(Previous names: ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans...)
(Previous symbol: UBE2G)
| |
Aliases
for UBE2G1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ubiquitin-Conjugating Enzyme E2G 11 2 | | Ubiquitin Carrier Protein G12 3 | | UBE2G1 2 3 5 | | Ubiquitin-Protein Ligase G12 3 | | UBC71 2 3 | | E217K2 3 | | Ubiquitin-Conjugating Enzyme E2G 1 (Homologous To C. Elegans UBC7)1 2 | | EC 6.3.2.193 8 | | Ubiquitin-Conjugating Enzyme E2G 1 (UBC7 Homolog, C. Elegans)1 2 | | Ubiquitin-Conjugating Enzyme E2 G12 | | Ubiquitin-Conjugating Enzyme E2G 1 (UBC7 Homolog, Yeast)1 2 | | |
Export aliases for UBE2G1 gene to outside databasesPrevious GC identifers: GC17M004492 GC17M004124 GC17M004380 GC17M004061 |
Summaries
for UBE2G1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for UBE2G1:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, orE1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of theE2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. Theprotein may be involved in degradation of muscle-specific proteins. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: UB2G1_HUMAN, P62253Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitrocatalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specificproteins. Mediates polyubiquitination of CYP3A4
Gene Wiki entry for UBE2G1
|
Genomic Views
for UBE2G1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the UBE2G1 gene promoter:
Pax-5 MyoD LCR-F1 Roaz Arnt AREB6 POU2F1 POU2F1a Pax-4a MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for UBE2G1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2G1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.2 Ensembl cytogenetic band: 17p13.2 HGNC cytogenetic band: 17p13.2UBE2G1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M004120: view genomic region
(about GC identifiers)
Start:
|
4,172,512 bp from pter |
End:
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4,269,969 bp from pter |
Size:
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97,458 bases |
Orientation:
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minus strand |
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Proteins
for UBE2G1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: UB2G1_HUMAN, P62253 (See
protein sequence)Recommended Name: Ubiquitin-conjugating enzyme E2 G1 Size: 170 amino acids; 19509 Da
Sequence caution: Sequence=AAH26288.2; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for UBE2G1:2AWF (3D)
Secondary accessions: B2R7P2 D3DTK0 Q99462Explore the universe of human proteins at neXtProt for UBE2G1: NX_P62253
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62253
4 DME Specific Peptides for UBE2G1 (P62253)
UBE2G1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003333.1
ENSEMBL proteins: ENSP00000380178 ENSP00000459691 ENSP00000458253 ENSP00000459847 ENSP00000467502 ENSP00000459485 Reactome Protein details: P62253
Human Recombinant Protein Products for UBE2G1:
UBE2G1 Antibody Products:
Assay Products for UBE2G1: |
Protein
Domains /
Families
for UBE2G1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
UBE2G1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62253ProtoNet protein and cluster: P62253 1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes
UniProtKB/Swiss-Prot: UB2G1_HUMAN, P62253Similarity: Belongs to the ubiquitin-conjugating enzyme family |
Function
for UBE2G1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: UB2G1_HUMAN, P62253Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitrocatalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specificproteins. Mediates polyubiquitination of CYP3A4Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine Genatlas biochemistry entry for UBE2G1:ubiquitin conjugating enzyme E2G,highly homolog to C elegans UBC7,highly expressed in skeletal muscle
Enzyme Number (IUBMB): EC 6.3.2.191 2
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
UBE2G1 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for UBE2G1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2G1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2G1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: UBE2G1 (NM_003342) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2G1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2G1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2G1 |
|
Pathways & Interactions
for UBE2G1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway | | | 3 | Immune System | | | 4 | Parkinsons Disease Pathway | | | 5 | Ubiquitin-Proteasome Dependent Proteolysis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for UBE2G1
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for UBE2G1
1  GeneGo (Thomson Reuters) Pathway for UBE2G1
2  BioSystems Pathways for UBE2G1
5 
Reactome Pathways for UBE2G1
3 
Kegg Pathways (Kegg details for UBE2G1):
UniProtKB/Swiss-Prot: UB2G1_HUMAN, P62253Pathway: Protein modification; protein ubiquitination
UBE2G1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for UBE2G1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/16 Interacting proteins for UBE2G1 (P622533 ENSP000003801784) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process |
TAS | 8893823 | | GO:0070534 | protein K63-linked ubiquitination |
IDA | -- | | GO:0070936 | protein K48-linked ubiquitination |
IDA | -- |
UBE2G1 for ontologies About GeneDecksing
|
Drugs & Compounds
for UBE2G1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for UBE2G1
4 HMDB Compounds for UBE2G1 About this table
Search CenterWatch for drugs/clinical trials and news about UBE2G1 / UB2G1
|
Transcripts
for UBE2G1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for UBE2G1 gene (2 alternative transcripts): NM_003342.4 NM_182682.2 Unigene Cluster for UBE2G1: Ubiquitin-conjugating enzyme E2G 1 Hs.741319 [show with all ESTs]Unigene Representative Sequence: NM_0033426 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396981(uc002fxs.3) ENST00000572484 ENST00000574633 ENST00000571980
ENST00000571953 ENST00000574059
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2G1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2G1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: UBE2G1 (NM_003342) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for UBE2G1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2G1 |
Additional cDNA sequence: AK313059.1 BC002775.2 BC017006.1 BC026288.1 BT007416.1 D78514.1 10 DOTS entries: DT.444928 DT.97847027 DT.95333171 DT.100789880 DT.100789882 DT.91751363 DT.120910165 DT.445070 DT.75172367 DT.91742715 24/350 AceView cDNA sequences (see all 350): BG677778 AA631318 BE673128 CK820173 AU125343 BC017006 AA125858 BM714770 AA593118 AW016088 BU740015 AA814632 BQ883781 AI369063 BP336479 BM474019 BF982430 Z42739 BQ924413 BM142249 AW959202 AI627437 AI358757 Z38893
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2G1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for UBE2G1
|
Expression
for UBE2G1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| UBE2G1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGATGAGTGC
About this image
See UBE2G1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for UBE2G1
SOURCE GeneReport for Unigene cluster: Hs.741319
UniProtKB/Swiss-Prot: UB2G1_HUMAN, P62253Tissue specificity: Widely expressed, mainly in skeletal muscle
SABiosciences Expression via Pathway-Focused PCR Array including UBE2G1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2G1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat UBE2G1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2G1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2G1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2G1 |
Orthologs
for UBE2G1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for UBE2G1 gene from 8/36 species (see all 36) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
UBE2G11 |
ubiquitin-conjugating enzyme E2G 1 |
88.63(n)
100(a) |
|
770961 NM_001080883.1 NP_001074352.1 |
lizard
(Anolis carolinensis) |
Reptilia |
UBE2G16 |
-- |
94(a) |
1 ↔ 1 |
GL343393.1(317770-321522) |
African clawed frog
(Xenopus laevis) |
Amphibia |
ube2g1-prov2 |
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. more |
86.94(n) |
|
BC047985.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufi33c042 |
wufi33c04 |
85.16(n) |
|
334133 BC045512.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG96023
CG400451 |
ubiquitin-protein ligase3
CG400451 |
77(a)3
74.34(n)1
84.24(a)1 |
|
87F123
33550791 NM_001043175.21 NP_001036640.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
ubc-73 |
Ubiquitin conjugating enzyme |
74(a) |
|
III(9701985-9702983) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
UBC131 |
ubiquitin-conjugating enzyme E2 13 |
64.6(n)
63.98(a) |
|
823796 NM_114513.5 NP_566884.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.126032 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
71.66(n) |
|
AK104148.1 |
ENSEMBL Gene Tree for UBE2G1 (if available)
TreeFam Gene Tree for UBE2G1 (if available) |
Paralogs
for UBE2G1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for UBE2G1 gene
- UBE2G22
18/24 SIMAP similar genes for UBE2G1 using alignment to 5 protein entries: UB2G1_HUMAN (see all proteins)
(see all similar genes):UBE2G2 CDC34 UBE2R2 DKFZp586L2318 UBE2N UBE2D3
UBE2A UBE2D1 UBE2B HR6A UBE2U UBE2D4
UBE2F UBE2E2 UBE2K UBE2E1 UBE2S UBE2T
UBE2G1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for UBE2G1
PGOHUM00000245254
|
Genomic Variants
for UBE2G1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for UBE2G1 (4172512 - 4269969 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for UBE2G1
3 CNVs: 49862 49863 4984 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2G1 |
|
Disorders
/ Diseases
for UBE2G1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
UBE2G1 for disorders About GeneDecksing
OMIM gene information: 601569
OMIM disorders: --
3  diseases for UBE2G1: About MalaCardscri-du-chat syndrome parkinson's disease malaria
1 disease from the University of Copenhagen DISEASES database for UBE2G1:Cri-Du-Chat syndrome Export disorders for UBE2G1 gene to outside databases
|
Publications
for UBE2G1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for UBE2G1 gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with UBE2G1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans. (PubMed id 8893823)1, 2, 3 Watanabe T.K.... Takahashi E. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2. (PubMed id 12933904)1, 9 Kim B.W....Bianco A.C. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- The E3 ubiquitin ligase ITCH negatively regulates cano nical Wnt signaling by targeting dishevelled protein. (PubMed id 22826439)1 Wei W....Li L. (2012)
- F-box protein FBXL2 targets cyclin D2 for ubiquitinati on and degradation to inhibit leukemic cell proliferation. (PubMed id 22323446)1 Chen B.B....Mallampalli R.K. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for UBE2G1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE2G1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing UBE2G1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBE2G1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for UBE2G1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for UBE2G1 gene:
Search GeneIP for patents involving UBE2G1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for UBE2G1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for UBE2G1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for UBE2G1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for UBE2G1 | | | OriGene Protein Over-expression Lysate for UBE2G1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for UBE2G1 | | OriGene 3'-UTR Clone for UBE2G1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2G1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for UBE2G1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for UBE2G1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for UBE2G1 | | OriGene Custom Protein Services for UBE2G1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat UBE2G1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing UBE2G1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat UBE2G1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat UBE2G1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat UBE2G1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat UBE2G1 |
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| | | | Search Tocris compounds for UBE2G1 |
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 | | | UBE2G1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for UBE2G1 |
|  |  |  |  | | | | ThermoFisher Antibodies for UBE2G1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat UBE2G1 |
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