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Aliases for UBE2F-SCLY Gene

Subcategory (RNA class) for UBE2F-SCLY Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for UBE2F-SCLY Gene

  • UBE2F-SCLY Readthrough (NMD Candidate) 2 3 5

External Ids for UBE2F-SCLY Gene

Previous GeneCards Identifiers for UBE2F-SCLY Gene

  • GC02U902381
  • GC02P238877
  • GC02P238882

Summaries for UBE2F-SCLY Gene

Entrez Gene Summary for UBE2F-SCLY Gene

  • This locus represents naturally occurring read-through transcription between the neighboring UBE2F (ubiquitin-conjugating enzyme E2F) and SCLY (selenocysteine lyase) genes on chromosome 2. The read-through transcript is a candidate for non-sense mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for UBE2F-SCLY Gene

UBE2F-SCLY (UBE2F-SCLY Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Among its related pathways are Immune System and Integrated Breast Cancer Pathway. GO annotations related to this gene include acid-amino acid ligase activity. An important paralog of this gene is UBE2M.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBE2F-SCLY Gene

Genomics for UBE2F-SCLY Gene

Regulatory Elements for UBE2F-SCLY Gene

Promoters for UBE2F-SCLY Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around UBE2F-SCLY on UCSC Golden Path with GeneCards custom track

Genomic Location for UBE2F-SCLY Gene

Chromosome:
2
Start:
237,966,945 bp from pter
End:
238,099,413 bp from pter
Size:
132,469 bases
Orientation:
Plus strand

Genomic View for UBE2F-SCLY Gene

Genes around UBE2F-SCLY on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBE2F-SCLY Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBE2F-SCLY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2F-SCLY Gene

Proteins for UBE2F-SCLY Gene

  • Protein details for UBE2F-SCLY Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BSR4
    Recommended name:
    Protein UBE2F-SCLY
    Protein Accession:
    H3BSR4

    Protein attributes for UBE2F-SCLY Gene

    Size:
    131 amino acids
    Molecular mass:
    15021 Da
    Quaternary structure:
    No Data Available
  • Protein details for UBE2F-SCLY Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BUI7
    Recommended name:
    Protein UBE2F-SCLY
    Protein Accession:
    H3BUI7

    Protein attributes for UBE2F-SCLY Gene

    Size:
    73 amino acids
    Molecular mass:
    8085 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2F-SCLY Gene

Proteomics data for UBE2F-SCLY Gene at MOPED

Post-translational modifications for UBE2F-SCLY Gene

No Post-translational modifications

Other Protein References for UBE2F-SCLY Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for UBE2F-SCLY Gene

Domains & Families for UBE2F-SCLY Gene

Protein Domains for UBE2F-SCLY Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with UBE2F-SCLY: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for UBE2F-SCLY Gene

Function for UBE2F-SCLY Gene

Phenotypes for UBE2F-SCLY Gene

genes like me logo Genes that share phenotypes with UBE2F-SCLY: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBE2F-SCLY Gene

Localization for UBE2F-SCLY Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for UBE2F-SCLY Gene

Pathways & Interactions for UBE2F-SCLY Gene

genes like me logo Genes that share pathways with UBE2F-SCLY: view

Pathways by source for UBE2F-SCLY Gene

Interacting Proteins for UBE2F-SCLY Gene

Gene Ontology (GO) - Biological Process for UBE2F-SCLY Gene

None

No data available for SIGNOR curated interactions for UBE2F-SCLY Gene

Drugs & Compounds for UBE2F-SCLY Gene

No Compound Related Data Available

Transcripts for UBE2F-SCLY Gene

mRNA/cDNA for UBE2F-SCLY Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2F-SCLY Gene

No ASD Table

Relevant External Links for UBE2F-SCLY Gene

GeneLoc Exon Structure for
UBE2F-SCLY
ECgene alternative splicing isoforms for
UBE2F-SCLY

Expression for UBE2F-SCLY Gene

mRNA expression in normal human tissues for UBE2F-SCLY Gene

Protein differential expression in normal tissues from HIPED for UBE2F-SCLY Gene

This gene is overexpressed in Platelet (8.5), Lymph node (7.5), and Uterus (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb for UBE2F-SCLY Gene



genes like me logo Genes that share expression patterns with UBE2F-SCLY: view

Protein tissue co-expression partners for UBE2F-SCLY Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for UBE2F-SCLY Gene

Orthologs for UBE2F-SCLY Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UBE2F-SCLY Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia UBE2F 36
  • 69 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 69 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm5434 36
  • 60 (a)
ManyToMany
Ube2f 36
  • 68 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 49 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia UBE2F 36
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves UBE2F 36
  • 57 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 62 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ube2f 36
  • 54 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ubc-12 36
  • 27 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UBC12 36
  • 14 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3148 36
  • 27 (a)
OneToMany
Species with no ortholog for UBE2F-SCLY:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for UBE2F-SCLY Gene

ENSEMBL:
Gene Tree for UBE2F-SCLY (if available)
TreeFam:
Gene Tree for UBE2F-SCLY (if available)

Paralogs for UBE2F-SCLY Gene

Paralogs for UBE2F-SCLY Gene

(1) SIMAP similar genes for UBE2F-SCLY Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with UBE2F-SCLY: view

Variants for UBE2F-SCLY Gene

Sequence variations from dbSNP and Humsavar for UBE2F-SCLY Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs843976 -- 238,055,420(-) gcctc(C/T)caagt intron-variant
rs843977 -- 238,049,525(-) ctcct(A/G)agttc intron-variant
rs821485 -- 238,058,166(-) gggct(C/T)ggcgg intron-variant
rs821486 -- 238,058,050(-) gtgcc(A/G)gccca intron-variant
rs821487 -- 238,056,286(-) TGCCA(A/G)AGGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UBE2F-SCLY Gene

Variant ID Type Subtype PubMed ID
nsv508205 CNV Loss 20534489
nsv214866 CNV Loss 16902084
nsv876062 CNV Loss 21882294
esv2721743 CNV Deletion 23290073
esv2194763 CNV Deletion 18987734
esv2721744 CNV Deletion 23290073
esv2721745 CNV Deletion 23290073
nsv508894 CNV Insertion 20534489
dgv4460n71 CNV Loss 21882294
esv2721746 CNV Deletion 23290073
esv1081669 CNV Insertion 17803354

Relevant External Links for UBE2F-SCLY Gene

HapMap Linkage Disequilibrium report
UBE2F-SCLY

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for UBE2F-SCLY Gene

Disorders for UBE2F-SCLY Gene

Relevant External Links for UBE2F-SCLY

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
UBE2F-SCLY

No disorders were found for UBE2F-SCLY Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBE2F-SCLY Gene

Publications for UBE2F-SCLY Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for UBE2F-SCLY Gene

Sources for UBE2F-SCLY Gene

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