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Aliases for UBE2F-SCLY Gene

Subcategory (RNA class) for UBE2F-SCLY Gene


Quality Score for this RNA gene is


Aliases for UBE2F-SCLY Gene

  • UBE2F-SCLY Readthrough (NMD Candidate) 2 3 5

External Ids for UBE2F-SCLY Gene

Previous GeneCards Identifiers for UBE2F-SCLY Gene

  • GC02U902381
  • GC02P238877
  • GC02P238882

Summaries for UBE2F-SCLY Gene

Entrez Gene Summary for UBE2F-SCLY Gene

  • This locus represents naturally occurring read-through transcription between the neighboring UBE2F (ubiquitin-conjugating enzyme E2F) and SCLY (selenocysteine lyase) genes on chromosome 2. The read-through transcript is a candidate for non-sense mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for UBE2F-SCLY Gene

UBE2F-SCLY (UBE2F-SCLY Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include acid-amino acid ligase activity. An important paralog of this gene is UBE2F.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBE2F-SCLY Gene

Genomics for UBE2F-SCLY Gene

Regulatory Elements for UBE2F-SCLY Gene

Enhancers for UBE2F-SCLY Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F237997 1.1 Ensembl ENCODE 0.3 +31.6 31602 1.8 SOX13 PKNOX1 MXI1 TBL1XR1 ZNF384 CDC5L EBF1 YBX1 PLRG1 RFX5 UBE2F RNU6-1333P SCLY ESPNL RAMP1 ILKAP UBE2F-SCLY
GH02F237980 0.4 Ensembl 0.4 +13.5 13456 1.6 SOX13 RAMP1 SCLY UBE2F UBE2F-SCLY RNU6-1333P
GH02F237983 0.5 Ensembl 0.3 +17.2 17156 1.0 ZFHX2 MNT EGR2 RNU6-1333P SCLY RAMP1 UBE2F-SCLY
GH02F237979 0.2 Ensembl 0.4 +12.4 12356 0.2 RAMP1 UBE2F-SCLY RNU6-1333P
GH02F238024 0.4 ENCODE 0.2 +58.3 58315 0.8 BHLHE40 RNU6-1333P UBE2F-SCLY
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around UBE2F-SCLY on UCSC Golden Path with GeneCards custom track

Promoters for UBE2F-SCLY Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000610389 156 2200 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 SLC30A9 ZNF143 FOS
ENSR00001834238 1855 401 CTCF HDAC1 TFAP4 MXI1 TBL1XR1 SAP130 WRNIP1 SIN3A MAX RAD21

Genomic Location for UBE2F-SCLY Gene

237,966,945 bp from pter
238,099,413 bp from pter
132,469 bases
Plus strand

Genomic View for UBE2F-SCLY Gene

Genes around UBE2F-SCLY on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBE2F-SCLY Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBE2F-SCLY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2F-SCLY Gene

Proteins for UBE2F-SCLY Gene

  • Protein details for UBE2F-SCLY Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein UBE2F-SCLY
    Protein Accession:

    Protein attributes for UBE2F-SCLY Gene

    131 amino acids
    Molecular mass:
    15021 Da
    Quaternary structure:
    No Data Available
  • Protein details for UBE2F-SCLY Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein UBE2F-SCLY
    Protein Accession:

    Protein attributes for UBE2F-SCLY Gene

    73 amino acids
    Molecular mass:
    8085 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2F-SCLY Gene

Post-translational modifications for UBE2F-SCLY Gene

No Post-translational modifications

Other Protein References for UBE2F-SCLY Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for UBE2F-SCLY Gene

Domains & Families for UBE2F-SCLY Gene

Protein Domains for UBE2F-SCLY Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with UBE2F-SCLY: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for UBE2F-SCLY Gene

Function for UBE2F-SCLY Gene

Phenotypes for UBE2F-SCLY Gene

genes like me logo Genes that share phenotypes with UBE2F-SCLY: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBE2F-SCLY Gene

Localization for UBE2F-SCLY Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for UBE2F-SCLY Gene

Pathways & Interactions for UBE2F-SCLY Gene

SuperPathways for UBE2F-SCLY Gene

No Data Available

Interacting Proteins for UBE2F-SCLY Gene

Gene Ontology (GO) - Biological Process for UBE2F-SCLY Gene


No data available for Pathways by source and SIGNOR curated interactions for UBE2F-SCLY Gene

Transcripts for UBE2F-SCLY Gene


(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2F-SCLY Gene

No ASD Table

Relevant External Links for UBE2F-SCLY Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for UBE2F-SCLY Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UBE2F-SCLY Gene

Protein differential expression in normal tissues from HIPED for UBE2F-SCLY Gene

This gene is overexpressed in Platelet (8.5), Lymph node (7.5), and Uterus (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb and MOPED for UBE2F-SCLY Gene

Protein tissue co-expression partners for UBE2F-SCLY Gene

genes like me logo Genes that share expression patterns with UBE2F-SCLY: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for UBE2F-SCLY Gene

Orthologs for UBE2F-SCLY Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UBE2F-SCLY Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia UBE2F 35
  • 71 (a)
(Bos Taurus)
Mammalia UBE2F 35
  • 69 (a)
(Canis familiaris)
Mammalia -- 35
  • 69 (a)
(Mus musculus)
Mammalia Ube2f 35
  • 68 (a)
Gm5434 35
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 49 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 47 (a)
(Gallus gallus)
Aves UBE2F 35
  • 57 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 62 (a)
(Danio rerio)
Actinopterygii ube2f 35
  • 54 (a)
(Caenorhabditis elegans)
Secernentea ubc-12 35
  • 27 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UBC12 35
  • 14 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3148 35
  • 27 (a)
Species where no ortholog for UBE2F-SCLY was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for UBE2F-SCLY Gene

Gene Tree for UBE2F-SCLY (if available)
Gene Tree for UBE2F-SCLY (if available)

Paralogs for UBE2F-SCLY Gene

Paralogs for UBE2F-SCLY Gene

(1) SIMAP similar genes for UBE2F-SCLY Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with UBE2F-SCLY: view

Variants for UBE2F-SCLY Gene

Sequence variations from dbSNP and Humsavar for UBE2F-SCLY Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10048643 -- 237,989,292(+) GGTGG(A/G)TTGCA intron-variant
rs10048814 -- 237,989,113(+) CTTCC(C/T)TTAAA intron-variant
rs10166061 -- 237,997,869(+) AAAAG(C/T)GTCCA intron-variant
rs10167355 -- 238,017,965(+) TTGAC(G/T)TTTTA intron-variant
rs10169778 -- 238,054,003(+) atata(C/T)atata intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UBE2F-SCLY Gene

Variant ID Type Subtype PubMed ID
nsv979190 CNV duplication 23825009
nsv954241 CNV deletion 24416366
nsv953215 CNV deletion 24416366
nsv508894 CNV insertion 20534489
nsv508205 CNV deletion 20534489
nsv214866 CNV deletion 16902084
nsv1147114 CNV deletion 26484159
nsv1119483 CNV insertion 24896259
nsv1011723 CNV gain 25217958
nsv1000252 CNV loss 25217958
esv3561241 CNV deletion 23714750
esv3028587 CNV deletion 24192839
esv2721746 CNV deletion 23290073
esv2721745 CNV deletion 23290073
esv2721744 CNV deletion 23290073
esv2721743 CNV deletion 23290073
esv2194763 CNV deletion 18987734
esv1081669 CNV insertion 17803354
dgv4193n100 CNV gain 25217958

Relevant External Links for UBE2F-SCLY Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for UBE2F-SCLY Gene

Disorders for UBE2F-SCLY Gene

Relevant External Links for UBE2F-SCLY

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for UBE2F-SCLY Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBE2F-SCLY Gene

Publications for UBE2F-SCLY Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for UBE2F-SCLY Gene

Sources for UBE2F-SCLY Gene

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