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Aliases for UBE2F-SCLY Gene

Subcategory (RNA class) for UBE2F-SCLY Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for UBE2F-SCLY Gene

  • UBE2F-SCLY Readthrough (NMD Candidate) 2 3

External Ids for UBE2F-SCLY Gene

Summaries for UBE2F-SCLY Gene

Entrez Gene Summary for UBE2F-SCLY Gene

  • This locus represents naturally occurring read-through transcription between the neighboring UBE2F (ubiquitin-conjugating enzyme E2F) and SCLY (selenocysteine lyase) genes on chromosome 2. The read-through transcript is a candidate for non-sense mediated mRNA decay (NMD), and is unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for UBE2F-SCLY Gene

UBE2F-SCLY (UBE2F-SCLY Readthrough (NMD Candidate)) is a RNA Gene, and belongs to ncRNA RNA class. Among its related pathways are Class I MHC mediated antigen processing and presentation and Remodeling of Adherens Junctions. An important paralog of this gene is UBE2M.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBE2F-SCLY Gene

Genomics for UBE2F-SCLY Gene

Genomic Location for UBE2F-SCLY Gene

Start:
237,966,945 bp from pter
End:
238,099,413 bp from pter
Size:
132,469 bases
Orientation:
Plus strand

Genomic View for UBE2F-SCLY Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBE2F-SCLY Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2F-SCLY Gene

No data available for Regulatory Elements for UBE2F-SCLY Gene

Proteins for UBE2F-SCLY Gene

  • Protein details for UBE2F-SCLY Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BSR4-H3BSR4
    Recommended name:
    Protein UBE2F-SCLY
    Protein Accession:
    H3BSR4
    Secondary Accessions:

    Protein attributes for UBE2F-SCLY Gene

    Size:
    131 amino acids
    Molecular mass:
    15021 Da
    Quaternary structure:
    No Data Available
  • Protein details for UBE2F-SCLY Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BUI7-H3BUI7
    Recommended name:
    Protein UBE2F-SCLY
    Protein Accession:
    H3BUI7
    Secondary Accessions:

    Protein attributes for UBE2F-SCLY Gene

    Size:
    73 amino acids
    Molecular mass:
    8085 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2F-SCLY Gene

Proteomics data for UBE2F-SCLY Gene at MOPED

Post-translational modifications for UBE2F-SCLY Gene

No Post-translational modifications

Other Protein References for UBE2F-SCLY Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for UBE2F-SCLY Gene

Domains for UBE2F-SCLY Gene

Protein Domains for UBE2F-SCLY Gene

genes like me logo Genes that share domains with UBE2F-SCLY: view

No data available for Gene Families and UniProtKB/Swiss-Prot for UBE2F-SCLY Gene

Function for UBE2F-SCLY Gene

Gene Ontology (GO) - Molecular Function for UBE2F-SCLY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016881 acid-amino acid ligase activity --
genes like me logo Genes that share ontologies with UBE2F-SCLY: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for UBE2F-SCLY Gene

Localization for UBE2F-SCLY Gene

No data available for Gene Ontology (GO) - Cellular Components for UBE2F-SCLY Gene

Pathways for UBE2F-SCLY Gene

genes like me logo Genes that share pathways with UBE2F-SCLY: view

Pathways by source for UBE2F-SCLY Gene

Interacting Proteins for UBE2F-SCLY Gene

Gene Ontology (GO) - Biological Process for UBE2F-SCLY Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
genes like me logo Genes that share ontologies with UBE2F-SCLY: view

Transcripts for UBE2F-SCLY Gene

mRNA/cDNA for UBE2F-SCLY Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2F-SCLY Gene

No ASD Table

Relevant External Links for UBE2F-SCLY Gene

GeneLoc Exon Structure for
UBE2F-SCLY
ECgene alternative splicing isoforms for
UBE2F-SCLY

Expression for UBE2F-SCLY Gene

mRNA expression in normal human tissues for UBE2F-SCLY Gene

Integrated Proteomics: protein expression from PaxDb for UBE2F-SCLY Gene

genes like me logo Genes that share expressions with UBE2F-SCLY: view

Orthologs for UBE2F-SCLY Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UBE2F-SCLY Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBE2F 37
  • 71 (a)
OneToOne
cow
(Bos Taurus)
Mammalia UBE2F 37
  • 69 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 69 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm5434 37
  • 60 (a)
ManyToMany
Ube2f 37
  • 68 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 49 (a)
OneToMany
chicken
(Gallus gallus)
Aves UBE2F 37
  • 57 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 62 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ube2f 37
  • 54 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea ubc-12 37
  • 27 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UBC12 37
  • 14 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3148 37
  • 27 (a)
OneToMany
Species with no ortholog for UBE2F-SCLY:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for UBE2F-SCLY Gene

ENSEMBL:
Gene Tree for UBE2F-SCLY (if available)
TreeFam:
Gene Tree for UBE2F-SCLY (if available)

Paralogs for UBE2F-SCLY Gene

Paralogs for UBE2F-SCLY Gene

Selected SIMAP similar genes for UBE2F-SCLY Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with UBE2F-SCLY: view

Variants for UBE2F-SCLY Gene

Sequence variations from dbSNP and Humsavar for UBE2F-SCLY Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs821485 -- 238,058,166(-) gggct(C/T)ggcgg intron-variant
rs821486 -- 238,058,050(-) gtgcc(A/G)gccca intron-variant
rs821487 -- 238,056,286(-) TGCCA(A/G)AGGAC intron-variant
rs821488 -- 238,055,115(-) gtggc(A/G)tgatc intron-variant
rs821489 -- 238,052,731(-) atACC(C/G)TAGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for UBE2F-SCLY Gene

Variant ID Type Subtype PubMed ID
nsv508205 CNV Loss 20534489
nsv214866 CNV Loss 16902084
nsv876062 CNV Loss 21882294
esv2721743 CNV Deletion 23290073
esv2194763 CNV Deletion 18987734
esv2721744 CNV Deletion 23290073
esv2721745 CNV Deletion 23290073
nsv508894 CNV Insertion 20534489
dgv4460n71 CNV Loss 21882294
esv2721746 CNV Deletion 23290073
esv1081669 CNV Insertion 17803354

Relevant External Links for UBE2F-SCLY Gene

HapMap Linkage Disequilibrium report
UBE2F-SCLY

Disorders for UBE2F-SCLY Gene

No disorders were found for UBE2F-SCLY Gene.

No data available for UniProtKB/Swiss-Prot for UBE2F-SCLY Gene

Publications for UBE2F-SCLY Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3

Products for UBE2F-SCLY Gene

Sources for UBE2F-SCLY Gene

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