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UBE2E1 Gene

protein-coding   GIFtS: 60

GC03P023822
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
(Previous name: ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for UBE2E1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
EC 6.3.2.19 3
UBCH6 2, 3
UbcH6 1, 3
Descriptions
Ubiquitin carrier protein E1 2, 3
Ubiquitin-protein ligase E1 2, 3
ubiquitin-conjugating enzyme E2E 1 2
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) 2
ubiquitin-conjugating enzyme E2E 1 (homologous to yeast
UBC4/5) 1, 2
External Ids
HGNC: 124771
Entrez Gene: 73242
UniProtKB: P519653
Ensembl: ENSG000001701427
Search outside databases for aliases for UBE2E1 gene

Previous GC identifers: GC03M023441 GC03P023529 GC03P023697

Summaries
for UBE2E1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for UBE2E1:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting
abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes
of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and
ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating
enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been
found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: UB2E1_HUMAN, P51965
Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective
degradation of short-lived and abnormal proteins

Gene Wiki entry for UBE2E1

Genomic Location
for UBE2E1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the UBE2E1 gene  

Entrez Gene cytogenetic band: 3p24.2   Ensembl cytogenetic band:  3p24.2   HGNC cytogenetic band: 3p24.2

UBE2E1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P023822:     (about GC identifiers)

Start:
 23,822,443 bp from pter
End:
 23,907,811 bp from pter
Size:
 85,369 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000003.10  NT_022517.17  

Proteins
for UBE2E1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: UB2E1_HUMAN, P51965 (See protein sequence)
Recommended Name: Ubiquitin-conjugating enzyme E2 E1  
Size: 193 amino acids; 21404 Da
Subunit: Interacts with RNF14
PDB structure from and Proteopedia :
1XR9 (3D)    3BZH (3D)    

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_003332.1  NP_872607.1  


    ENSEMBL proteins: 
    ENSP00000303709 ENSP00000329113 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant UBE2E1 Protein
    Sigma-Aldrich Proteins for UBE2E1  
    Browse R&D Systems for human recombinant proteins
    Enzo Life Sciences proteins for UBE2E1
    Recombinant Proteins from Abcam (UBCH6/UBE2E1)
    Human Recombinant Proteins from Abnova (UBE2E1)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654 nucleoplasm EXP10548110 11340163 15029244
    GO:0005829 cytosol EXP10793135 11285280 11535616 11742988 12070128
    About this table

    Antibodies for UBE2E1: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of UBE2E1
    Browse Antibodies at Sigma-Aldrich
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (UBCH6/UBE2E1), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Search Novus for antibodies for UBE2E1

    Assays for UBE2E1: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Enzo Life Sciences assays for UBE2E1

    Protein Domains/
    Families
    for UBE2E1

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro domains/families:
     IPR000608 UBQ-conjugat_E2
     IPR016135 UBQ-conjugat/RWD-like


       GeneDecks  UBE2E1 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P51965

    ProtoNet protein and cluster: P51965

    1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes

    UniProtKB/Swiss-Prot: UB2E1_HUMAN, P51965
    Similarity: Belongs to the ubiquitin-conjugating enzyme family

    Gene Function
    for UBE2E1

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (UBE2E1)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_182666

                  Applied Biosystems Silencer® siRNAs for UBE2E1

                  Sigma-Aldrich siRNA and siRNA Panels for UBE2E1  
                         Sigma-Aldrich shRNA Panels and shRNA for UBE2E1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for UBE2E1
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003341
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003341
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_003341 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_003341

    UniProtKB/Swiss-Prot: UB2E1_HUMAN, P51965
    Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective
    degradation of short-lived and abnormal proteins
    Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein
    N-ubiquityllysine
    Enzyme Number (IUBMB): EC 6.3.2.19 

    1 MGI phenotypic allele for Ube2e1 (no phenotypes)


    4 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842 ubiquitin-protein ligase activity TAS8576257
    GO:0005515 protein binding IPI14667819
    GO:0016874 ligase activity IEA--
    GO:0042296 ISG15 ligase activity IDA16428300
    About this table

    Pathways & Interactions
    for UBE2E1

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    1 Invitrogen iPath™ Online BioAtlas - Pathway for UBE2E1 (Maps provided by GeneGo):
     Putative ubiquitin pathway

       GeneDecks  UBE2E1 for the pathways selected above  
    About GeneDecksing

    2 Millipore Pathways for UBE2E1
     Common schema of ubiquitination
     Proteolysis Putative ubiquitin pathway

       GeneDecks  UBE2E1 for the pathways selected above  
    About GeneDecksing

    2 Sigma-Aldrich "Your Favorite Gene" Pathways for  UBE2E1  (Your Favorite Gene powered by Ingenuity) 
     Hypoxia Signaling in the Cardiovascular System
     Protein Ubiquitination Pathway

       GeneDecks  UBE2E1 for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for UBE2E1):
     hsa04120 Ubiquitin mediated proteolysis

       GeneDecks  UBE2E1 for the pathways selected above  
    About GeneDecksing
    UniProtKB/Swiss-Prot: UB2E1_HUMAN, P51965
    Pathway: Protein modification; protein ubiquitination

     Gene Network CentralTM Interacting Genes and Proteins Network for  UBE2E1 


    5/96 Interacting proteins for UBE2E1 (P519651, 2 ENSP000003037093) via UniProtKB, MINT, and/or STRING (see all 96 )

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000183574Q999421, 2EBI-348546, EBI-348482 MINT-62577 MINT-62675 MINT-62751
    ENSG00000206254Q999421, 2EBI-348546, EBI-348482 MINT-62577 MINT-62675 MINT-62751
    RNF5Q999421, 2EBI-348546, EBI-348482 MINT-62577 MINT-62675 MINT-62751 EBI-348546, EBI-348482 MINT-62577 MINT-62675 MINT-62751
    RNF5Q999421, 2EBI-348546, EBI-348482 MINT-62577 MINT-62675 MINT-62751 EBI-348546, EBI-348482 MINT-62577 MINT-62675 MINT-62751
    UBCENSP000003448183STRING (score=.986)
    About this table

    5/7 Gene Ontology (GO) biological process terms (links to tree view) (see all 7 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006511 ubiquitin-dependent protein catabolic process TAS8576257
    GO:0016567 protein ubiquitination IDA9990509
    GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process EXP11285280
    GO:0032020 ISG15-protein conjugation IDA16428300
    GO:0051246 regulation of protein metabolic process IEA--
    About this table

    Drugs & Compounds
    for UBE2E1

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for UBE2E1

    Transcripts
    for UBE2E1

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (UBE2E1)
    Browse for Gene Knock-down Tools from Millipore
    Browse Abnova for Chimera RNAi Products
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_182666

                  Sigma-Aldrich siRNA and siRNA Panels for UBE2E1  
                         Sigma-Aldrich shRNA Panels and shRNA for UBE2E1  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_003341  NM_182666  

    REFSEQ mRNAs for UBE2E1 gene (2 alternative transcripts): 

    NM_003341.3   NM_182666.1   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_003341  NM_182666  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_003341
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_003341
                                     untagged cDNA clones in CMV expression vector (see all 3): NM_003341 

    Additional cDNA sequence: 

    AK295354.1 AK314854.1 BC009139.1 CR605474.1 CR609756.1 CR622042.1 CR624061.1 X92963.1 

    11 DOTS entries:

    DT.318024  DT.95277632  DT.97765958  DT.91742794  DT.91742798  DT.95277631  DT.95303824  DT.120907446 
    DT.120907453  DT.100796684  DT.75180231 

    24/231 AceView cDNA sequences (see all 231 ):

    BQ924649 BQ015123 CD364807 N31627 R70937 AI784674 W25345 W80524 
    AA356669 CD675918 AI022520 BM762205 CD106559 BU632355 N22211 CR624061 
    AW439873 CB131622 AI973239 BM090873 NM_003341 BU738239 AA889986 AA173713 

    highest scoring ESTs for UBE2E1:

    AA027117 AA056543 AA056646 AA129173 AA173547 AA173713 AA321836 AA356669 AA576323 AA889986 

    Unigene Cluster for UBE2E1:

    Ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
    Hs.164853  [show with all ESTs]
    Unigene Representative Sequence: NM_003341


    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2E1 (see all 9 )

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d · 9e
    SP1:        -     -           -           -     -           -                                 
    SP2:              -           -           -     -           -                                 
    SP3:                          -           -     -           -                                 
    SP4:                          -           -                 -                                 
    SP5:        -     -     -     -           -     -           -                                 

    About this scheme

    ECgene alternative splicing isoforms for UBE2E1

    2 Ensembl transcripts including schematic representations:
    ENST00000306627  ENST00000346855  

    Expression
    for UBE2E1

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    UBE2E1 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for UBE2E1

    1 / 2 / 3

    3 probe-sets matching UBE2E1 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		37358_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AI039880 0.80 1.00 0.91 1

    		212519_at2, 3 U133-A 1 1.00 1.00 -- -- AL518159 0.60 1.00 0.82 1

    		212519_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ACAGAATGGC

    SOURCE GeneReport for Unigene cluster: Hs.164853

    Expression variation in blood from EXPOLDB for UBE2E1

    Orthologs
    for UBE2E1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for UBE2E1 gene from 5/15 species (see all 15 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 UBE2E11   -- ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, more 97.06(n)
    100(a)    		 477048  XM_534245.2  XP_534245.2 
    chimpanzee
    (Pan troglodytes)    		 UBE2E11   -- ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, more 100(n)
    100(a)    		 750105  XM_001173077.1  XP_001173077.1 
    cow
    (Bos taurus)    		 UBE2E11   -- ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, more 92.75(n)
    99.48(a)    		 615599  XM_867461.2  XP_872554.2 
    mouse
    (Mus musculus)    		 Ube2e11, 5 145
    		 ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog more1, 5 91.02(n)1
    98.96(a)1    		 221941  NM_009455.31  NP_033481.11 
     AK0901775  AK1482665  (see all 7)
    chicken
    (Gallus gallus)    		 UBE2E11   -- ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, more 87.05(n)
    99.48(a)    		 420653  XM_001235065.1  XP_001235066.1 
    About this table        Species with no ortholog for UBE2E1

    ENSEMBL Gene Tree for UBE2E1

    Paralogs
    for UBE2E1

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for UBE2E1 gene
    UBE2E32  UBE2E22  

    SNPs/Variants
    for UBE2E1

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/525 NCBI SNPs in UBE2E1 are shown (see all 525 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 117)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 3 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs11275071,2
    		C23907584(+) AAAACA/CCCATA 2 -- ut311Minor allele frequency- C:0.00MN 184
    --
    rs115416611,2
    		H23904146(+) GTATTC/ATTTCT 2 L/F mis14Minor allele frequency- A:0.00EU EA WA 406
    rs37627671,2
    		C23822215(-) AGGGGG/TCGAGG 2 -- ng51 trp30--------
    --
    rs170137511,2
    		F23821944(+) TGTGAT/-TTTTT 2 -- ng51 trp32Minor allele frequency- -:0.13MN EA 356
    rs14733791,2
    		A,C,F,H,O23848606(+) TCATGT/CCAGCC 2 -- int115Minor allele frequency- C:0.39NA EA EU WA 1300
    rs14710601,2
    		A,C,F,H,O23835419(+) AAAGTA/GTAAGA 2 -- int118Minor allele frequency- G:0.32NS MN EU EA WA NA 1338
    rs14733801,2
    		A,C,F,H,O23850121(+) ATTTCG/TTATAT 2 -- int15Minor allele frequency- T:0.41MN EU EA WA 602
    rs28848731,2
    		A,C,F,H23828189(+) GCTCAG/CTACTG 2 -- int14Minor allele frequency- C:0.01EU EA WA 410
    rs67747871,2
    		A,C,F,H23834065(+) TATCAT/CGTTAT 2 -- int115Minor allele frequency- C:0.26EU EA WA NA 1400
    rs65508081,2
    		A,C,F,H23896053(+) CTTCTC/TTTCGT 2 -- int17Minor allele frequency- T:0.12NA EU EA WA 524
    About this table

    HapMap Linkage Disequilibrium images for UBE2E1 (up to first 250kb)

    Disorders & Mutations
    for UBE2E1

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 602916

    Medical News
    for UBE2E1

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for UBE2E1

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/31 PubMed articles for UBE2E1 gene (see all 31 ):

    Search for UBE2E1

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing UBE2E1

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 7324 HGNC: 12477 AceView: UBE2E1 Ensembl:ENSG00000170142 euGenes: HUgn7324
    ECgene: UBE2E1 H-InvDB: UBE2E1

    Other Databases showing UBE2E1

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing UBE2E1

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    		   --

    Licensable Technologies
    for UBE2E1

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for UBE2E1

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for UBE2E1:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
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      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for UBE2E1-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for UBE2E1 Browse antibodies at Sigma-Aldrich
     Explore super-pooled esiRNAs Proteins for UBE2E1
     Lentivirus-delivered shRNAs for UBE2E1 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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     Recombinant & Natural Proteins  

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     Recombinant Proteins
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     Search OriGene for UBE2E1
     Search Tocris compounds for UBE2E1




     Assays/Proteins for UBE2E1
     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Search Novus for antibodies for UBE2E1

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