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Aliases for UBE2DNL Gene

Subcategory (RNA class) for UBE2DNL Gene

lncRNA

Aliases for UBE2DNL Gene

  • Ubiquitin-Conjugating Enzyme E2D N-Terminal Like (Pseudogene) 2 3
  • Ubiquitin-Conjugating Enzyme E2D N-Terminal Like Pseudogene 2
  • Ubiquitin-Conjugating Enzyme E2D N-Terminal Like 2
  • Ubiquitin-Conjugating Enzyme E2D N-Terminal-Like 4
  • Ubiquitin Carrier Protein D2-Like 4
  • Ubiquitin-Protein Ligase D2-Like 4
  • UBE2D2L 4

External Ids for UBE2DNL Gene

ORGUL Members for UBE2DNL Gene

Previous GeneCards Identifiers for UBE2DNL Gene

  • GC0XU900848
  • GC0XP084077
  • GC0XP084190
  • GC0XP084191
  • GC0XP084193
  • GC0XP084195
  • GC0XP084197

Summaries for UBE2DNL Gene

GeneCards Summary for UBE2DNL Gene

UBE2DNL (Ubiquitin-Conjugating Enzyme E2D N-Terminal Like (Pseudogene)) is a Pseudogene, and is affiliated with the lncRNA class. GO annotations related to this gene include acid-amino acid ligase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBE2DNL Gene

Genomics for UBE2DNL Gene

Regulatory Elements for UBE2DNL Gene

Genomic Location for UBE2DNL Gene

Start:
84,934,151 bp from pter
End:
84,934,890 bp from pter
Size:
740 bases
Orientation:
Plus strand

Genomic View for UBE2DNL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for UBE2DNL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2DNL Gene

Proteins for UBE2DNL Gene

  • Protein details for UBE2DNL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWF7-U2D2L_HUMAN
    Recommended name:
    Putative ubiquitin-conjugating enzyme E2 D2-like protein
    Protein Accession:
    Q8IWF7
    Secondary Accessions:

    Protein attributes for UBE2DNL Gene

    Size:
    75 amino acids
    Molecular mass:
    8761 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2DNL Gene

Proteomics data for UBE2DNL Gene at MOPED

Post-translational modifications for UBE2DNL Gene

No Post-translational modifications

No data available for DME Specific Peptides for UBE2DNL Gene

Domains for UBE2DNL Gene

Protein Domains for UBE2DNL Gene

Suggested Antigen Peptide Sequences for UBE2DNL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IWF7

UniProtKB/Swiss-Prot:

U2D2L_HUMAN :
  • Q8IWF7
Family:
  • Belongs to the ubiquitin-conjugating enzyme family.
genes like me logo Genes that share domains with UBE2DNL: view

No data available for Gene Families for UBE2DNL Gene

Function for UBE2DNL Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for UBE2DNL Gene

Localization for UBE2DNL Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for UBE2DNL Gene

Pathways for UBE2DNL Gene

SuperPathways for UBE2DNL Gene

No Data Available

Interacting Proteins for UBE2DNL Gene

Selected Interacting proteins: Q8IWF7-U2D2L_HUMAN for UBE2DNL Gene via I2D

Gene Ontology (GO) - Biological Process for UBE2DNL Gene

None

No data available for Pathways by source for UBE2DNL Gene

Transcripts for UBE2DNL Gene

mRNA/cDNA for UBE2DNL Gene

(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for UBE2DNL Gene

Ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene):
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for UBE2DNL

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2DNL Gene

No ASD Table

Relevant External Links for UBE2DNL Gene

GeneLoc Exon Structure for
UBE2DNL
ECgene alternative splicing isoforms for
UBE2DNL

Expression for UBE2DNL Gene

mRNA expression in normal human tissues for UBE2DNL Gene

mRNA differential expression in normal tissues according to GTEx for UBE2DNL Gene

This gene is overexpressed in Testis (50.9).

SOURCE GeneReport for Unigene cluster for UBE2DNL Gene Hs.460809

genes like me logo Genes that share expressions with UBE2DNL: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for UBE2DNL Gene

Orthologs for UBE2DNL Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for UBE2DNL Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Ube2dnl1 16
Species with no ortholog for UBE2DNL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for UBE2DNL Gene

ENSEMBL:
Gene Tree for UBE2DNL (if available)
TreeFam:
Gene Tree for UBE2DNL (if available)

Paralogs for UBE2DNL Gene

Selected SIMAP similar genes for UBE2DNL Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with UBE2DNL: view

No data available for Paralogs for UBE2DNL Gene

Variants for UBE2DNL Gene

Sequence variations from dbSNP and Humsavar for UBE2DNL Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs608096 -- 84,933,729(-) TAAAT(C/T)TATTT upstream-variant-2KB
rs768736 -- 84,932,956(+) CTCCC(A/G)GGAAG upstream-variant-2KB
rs6623210 -- 84,934,807(+) AGCTA(A/G)AGACT nc-transcript-variant
rs6653040 -- 84,933,550(+) ttttt(A/T)aaaaa upstream-variant-2KB
rs12013762 -- 84,934,491(+) CTCTA(C/T)CAGGC nc-transcript-variant

Relevant External Links for UBE2DNL Gene

HapMap Linkage Disequilibrium report
UBE2DNL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for UBE2DNL Gene

Disorders for UBE2DNL Gene

Relevant External Links for UBE2DNL

Genetic Association Database (GAD)
UBE2DNL
genes like me logo Genes that share disorders with UBE2DNL: view

No data available for UniProtKB/Swiss-Prot for UBE2DNL Gene

Publications for UBE2DNL Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PMID: 19549727) Markson G. … Sanderson C.M. (Genome Res. 2009) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 48

Products for UBE2DNL Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate UBE2DNL
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for UBE2DNL
    • Block miRNA regulation of UBE2DNL using miScript Target Protectors

    Sources for UBE2DNL Gene

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