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Aliases &
Descriptions
for UBE2D3P
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| EC 6.3.2.19 3 | | OTTHUMG00000031799 1 | | RP4-680N4 1, 2 | | UBCH5C 3 | | UBE2D3L 2 | | UBE2D5P 2 |
| | | Descriptions |
|---|
| E2(17)KB 3 3 | | Ubiquitin carrier protein D3 3 | | Ubiquitin-conjugating enzyme E2-17 kDa 3 3 | | Ubiquitin-protein ligase D3 3 | | ubiquitin-conjugating enzyme E2D 3 pseudogene 2 | | ubiquitin-conjugating enzyme E2D 5 pseudogene 1 |
|
| |
Search outside databases for aliases for UBE2D3P genePrevious GC identifers: GC20U900289 GC04M103937 |
Summaries
for UBE2D3P(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective
degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination
of p53/TP53 |
Genomic Location
for UBE2D3P
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p12.3 Ensembl cytogenetic band: 4q24 HGNC cytogenetic band: 20p12.3UBE2D3P Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M005222:
(about GC identifiers)
Start:
|
5,221,034 bp from pter |
End:
|
5,221,477 bp from pter |
Size:
|
444 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr4- 103,936,217-104,009,473 |
RefSeq DNA sequence:- NC_000020.9 NT_011387.8
| Proteins
for UBE2D3P
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077 (See
protein sequence)Recommended Name: Ubiquitin-conjugating enzyme E2 D3 Size: 147 amino acids; 16687 Da
PDB structure from  and Proteopedia  :1X23 (3D)
2FUH (3D)
Secondary accessions: A6NM99 P47986 Q6IB88 Q6NXS4
ENSEMBL proteins: ENSP00000337262 ENSP00000378282 ENSP00000318494 ENSP00000378283 ENSP00000337208 ENSP00000378280 ENSP00000344069 ENSP00000349722 ENSP00000378277 ENSP00000345285
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for UBE2D3P:
Assays for UBE2D3P: | Protein
Domains/
Families
for UBE2D3P(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P61077
ProtoNet protein and cluster: P61077 1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes
UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077Similarity: Belongs to the ubiquitin-conjugating enzyme family | Gene Function
for UBE2D3P
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
 Applied Biosystems Silencer® siRNAs for UBE2D3P
 Browse siRNA at Sigma-Aldrich
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
Browse Origene genome-wide validated SYBR primer pairs
UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective
degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination
of p53/TP53Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein
N-ubiquityllysineEnzyme Number (IUBMB): EC 6.3.2.19 | Pathways & Interactions
for UBE2D3P
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077Pathway: Protein modification; protein ubiquitination
4 Interacting proteins for UBE2D3P (ENSP000003440693 P610771, 2) via UniProtKB, MINT, and/or STRING| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ENSG00000183574 | Q999421, 2 | EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 | | ENSG00000206254 | Q999421, 2 | EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 | | RNF5 | Q999421, 2 | EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 | | RNF5 | Q999421, 2 | EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 | | -- | ensp: ENSP000003184943 | STRING (score=) |
About this table
|
Drugs & Compounds
for UBE2D3P(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for UBE2D3P
|
Transcripts
for UBE2D3P(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Browse siRNA at Sigma-Aldrich
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: XM_001725173
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
Additional cDNA sequence: XM_001725173.1 8 DOTS entries: DT.120803139 DT.97862577 DT.100684103 DT.100805383 DT.101969497 DT.121253183 DT.454162 DT.92463657 Unigene Cluster for UBE2D3P: Ubiquitin-conjugating enzyme E2D 3 pseudogene Hs.621190 [show with all ESTs]Unigene Representative Sequence: XM_001725173
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2D3P (see all 9
)
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for UBE2D3P
10 Ensembl transcripts including schematic representations: ENST00000350435
ENST00000394803
ENST00000321805
ENST00000394804
ENST00000338145
ENST00000394801
ENST00000349311
ENST00000357194
ENST00000394798
ENST00000343106
|
Expression
for UBE2D3P
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| UBE2D3P expression in normal and diseased human tissues
1 Data from GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.621190
|
Orthologs
for UBE2D3P
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for UBE2D3P gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
baker's yeast
(Saccharomyces cerevisiae) |
UBC5(YDR059C)4 |
4(569769-569233) |
Ubiquitin-conjugating enzyme that mediates selective more |
-- |
851631 NP_010344.1 |
About this table Species with no ortholog for UBE2D3P
ENSEMBL Gene Tree for UBE2D3P | Paralogs
for UBE2D3P(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for UBE2D3P gene
- UBE2D12 UBE2D42 UBE2D22
|
SNPs/Variants
for UBE2D3P(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations
for UBE2D3P
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for UBE2D3P(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for UBE2D3P (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for UBE2D3P gene: |
Search for UBE2D3P
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing UBE2D3P
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing UBE2D3P
(According to HUGE)
About This Section
| -- |
Specialized Databases showing UBE2D3P(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for UBE2D3P(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for UBE2D3P:
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Incremental update: 13 Oct 2009
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