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UBE2D3 Gene

protein-coding   GIFtS: 63

GC04M103936
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
(Previous name: ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
E2(17)KB3 2
EC 6.3.2.19 3
MGC43926 2
MGC5416 2
OTTHUMP00000161758 2
OTTHUMP00000161759 2
UBC4/5 2
UBCH5C 2, 3
UbcH5C 1
Descriptions
E2(17)KB 3 3
Ubiquitin carrier protein D3 3
Ubiquitin-conjugating enzyme E2-17 kDa 3 2, 3
Ubiquitin-protein ligase D3 3
ubiquitin carrier protein 2
ubiquitin-conjugating enzyme E2D 3 2
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 2
ubiquitin-conjugating enzyme E2D 3 (homologous to yeast
UBC4/5) 1, 2
External Ids
HGNC: 124761
Entrez Gene: 73232
UniProtKB: P610773
Ensembl: ENSG000001093327
Search outside databases for aliases for UBE2D3 gene

Previous GC identifers: GC04M104116 GC04M104026 GC04M104175 GC04M104074

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for UBE2D3:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting
abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes
of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and
ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating
enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53,
which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been
found for this gene, but the full-length nature of some variants has not been determined.
[provided by RefSeq]

UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077
Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective
degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination
of p53/TP53

Gene Wiki entry for UBE2D3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the UBE2D3 gene  

Entrez Gene cytogenetic band: 4q24   Ensembl cytogenetic band:  4q24   HGNC cytogenetic band: 4q24

UBE2D3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M103936:     (about GC identifiers)

Start:
103,936,217 bp from pter
End:
104,009,473 bp from pter
Size:
73,257 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000004.10  NT_016354.18  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077 (See protein sequence)
Recommended Name: Ubiquitin-conjugating enzyme E2 D3  
Size: 147 amino acids; 16687 Da
PDB structure from and Proteopedia :
1X23 (3D)    2FUH (3D)    
Secondary accessions: A6NM99 P47986 Q6IB88 Q6NXS4

REFSEQ proteins (9 alternative transcripts): 
NP_003331.1  NP_871615.1  NP_871616.1  NP_871617.1  NP_871618.1  NP_871619.1  NP_871620.1  NP_871621.1  
NP_871622.1  


ENSEMBL proteins: 
ENSP00000337262 ENSP00000378282 ENSP00000318494 ENSP00000378283 ENSP00000337208 ENSP00000378280 
ENSP00000344069 ENSP00000349722 ENSP00000378277 ENSP00000345285 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Millipore Purified and/or Recombinant UBE2D3 Protein
Sigma-Aldrich Proteins for UBE2D3  
Browse R&D Systems for human recombinant proteins
Enzo Life Sciences proteins for UBE2D3
Recombinant Proteins from Abcam (UBE2D3)
Human Recombinant Proteins from Abnova (UBE2D3)
               OriGene Purified Recombinant Human Proteins (see all 2): UBE2D3  


Antibodies for UBE2D3: 
Browse Antibodies Central at Invitrogen
Millipore Mono- and Polyclonal Antibodies for the study of UBE2D3
Sigma-Aldrich Antibodies for UBE2D3
Browse R&D Systems for Antibodies
Antibodies from Abcam (UBE2D3), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (UBE2D3)
Novus Biologicals Antibodies for UBE2D3

Assays for UBE2D3: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Enzo Life Sciences assays for UBE2D3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro domains/families:
 IPR000608 UBQ-conjugat_E2
 IPR016135 UBQ-conjugat/RWD-like


   GeneDecks  UBE2D3 for the domains selected above  
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Graphical View of Domain Structure for InterPro Entry P61077

ProtoNet protein and cluster: P61077

1 Blocks protein family: IPB000608 Ubiquitin-conjugating enzymes

UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077
Similarity: Belongs to the ubiquitin-conjugating enzyme family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (UBE2D3)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (UBE2D3)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 9): NM_181889

              Applied Biosystems Silencer® siRNAs for UBE2D3

              Sigma-Aldrich siRNA and siRNA Panels for UBE2D3  
                     Sigma-Aldrich shRNA Panels and shRNA for UBE2D3  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for UBE2D3
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 9): NM_003340
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 9): NM_003340
                                 untagged cDNA clones in CMV expression vector (see all 10): AK095822 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_181893

UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077
Function: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective
degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination
of p53/TP53
Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein
N-ubiquityllysine
Enzyme Number (IUBMB): EC 6.3.2.19 

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0004842 ubiquitin-protein ligase activity TAS8090726
GO:0005515 protein binding IPI14667819
GO:0016874 ligase activity IEA--
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(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Millipore Pathways for UBE2D3
 Selected targets of Oct-3/4
 Common schema of ubiquitination

   GeneDecks  UBE2D3 for the pathways selected above  
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for  UBE2D3  (Your Favorite Gene powered by Ingenuity) 
 Protein Ubiquitination Pathway
 Hypoxia Signaling in the Cardiovascular System

   GeneDecks  UBE2D3 for the pathways selected above  
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1 Kegg Pathway  (Kegg details for UBE2D3):
 hsa04120 Ubiquitin mediated proteolysis

   GeneDecks  UBE2D3 for the pathways selected above  
About GeneDecksing
UniProtKB/Swiss-Prot: UB2D3_HUMAN, P61077
Pathway: Protein modification; protein ubiquitination

 Gene Network CentralTM Interacting Genes and Proteins Network for  UBE2D3 


4 Interacting proteins for UBE2D3 (ENSP000003440693 P610771, 2) via UniProtKB, MINT, and/or STRING

InteractantInteraction Details
GeneCardExternal ID(s)
ENSG00000183574Q999421, 2EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580
ENSG00000206254Q999421, 2EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580
RNF5Q999421, 2EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580
RNF5Q999421, 2EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580 EBI-348268, EBI-348482 MINT-62678 MINT-62754 MINT-62580
--ensp: ENSP000003184943STRING (score=)
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4 Gene Ontology (GO) biological process terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006511 ubiquitin-dependent protein catabolic process TAS8530467
GO:0016567 protein ubiquitination IDA9990509
GO:0030509 BMP signaling pathway EXP15621726
GO:0051246 regulation of protein metabolic process IEA--
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for UBE2D3

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (UBE2D3)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (UBE2D3)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 9): NM_181889

              Sigma-Aldrich siRNA and siRNA Panels for UBE2D3  
                     Sigma-Aldrich shRNA Panels and shRNA for UBE2D3  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_003340  NM_181886  NM_181887  NM_181888  NM_181889  NM_181890  NM_181891  NM_181892  
NM_181893  

REFSEQ mRNAs for UBE2D3 gene (9 alternative transcripts): 

NM_003340.4   NM_181886.1   NM_181887.1   NM_181888.1   NM_181889.1   NM_181890.1   NM_181891.1   NM_181892.1   
NM_181893.1   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_003340  NM_181886  NM_181887  NM_181888  NM_181889  NM_181890  NM_181891  NM_181892  
NM_181893  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 9): NM_003340
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 9): NM_003340
                                 untagged cDNA clones in CMV expression vector (see all 10): AK095822 

Additional cDNA sequence: 

AK095822.1 AK124159.1 AK127304.1 AK315775.1 AL050186.1 AL833414.1 BC003395.1 BC037894.2 
BC066917.1 CR456916.1 CR596812.1 CR604221.1 CR608063.1 CR610934.1 CR619029.1 CR620503.1 
CR625720.1 U39318.1 

24/69 DOTS entries (see all 69 ):

DT.100684091  DT.100805383  DT.101969497  DT.101985597  DT.454162  DT.95273708  DT.97780980  DT.100684103 
DT.101985592  DT.97862577  DT.100039445  DT.100684107  DT.121253183  DT.95092051  DT.91788058  DT.100684106 
DT.91700781  DT.100684101  DT.121253022  DT.121253182  DT.121253306  DT.100684097  DT.95273714  DT.95273713 

24/782 AceView cDNA sequences (see all 782 ):

BU186980 CB162571 BU193254 BU677041 W46934 CR619029 CR618043 AA164993 
NM_181888 AI923982 BM541512 AW874003 AL535270 CA427172 AL050186 BX427697 
AW196905 CR604221 BQ007163 CA444507 BF432055 F11733 BU192219 CB409969 

highest scoring ESTs for UBE2D3:

AW020027 U39318 AV754305 BF215733 BF666811 BG613555 BM465843 BU570661 CD642889 AA017200 

Unigene Cluster for UBE2D3:

Ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
Hs.518773  [show with all ESTs]
Unigene Representative Sequence: AK127304


GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for UBE2D3 (see all 9 )

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
SP1:                    -     -     -     -     -     -                                                         
SP2:                                -     -     -     -                                                         
SP3:                                            -     -                                                         
SP4:                                                                                                            
SP5:              -     -     -     -     -     -     -                                                         

About this scheme

ECgene alternative splicing isoforms for UBE2D3

10 Ensembl transcripts including schematic representations:
ENST00000350435  ENST00000394803  ENST00000321805  ENST00000394804  ENST00000338145  ENST00000394801  
ENST00000349311  ENST00000357194  ENST00000394798  ENST00000343106  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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UBE2D3 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for UBE2D3

1 / 2 / 3

13 probe-sets matching UBE2D3 gene


Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

91086_at2, 3 U95-E 1 1.00 1.00 0.76 1.13 AW020027 0.80 1.00 0.91 1

60027_r_at2, 3 U95-C 1 1.00 1.00 0.44 0.13 N58386 0.60 1.00 0.82 1

504_at2, 3 U95-A 2 1.00 0.91 0.93 0.83 U39318 0.80 1.00 0.91 1

75179_at2, 3 U95-D 1 0.75 1.00 0.85 1.12 R81146 0.60 1.00 0.82 1

39083_at2, 3 U95-A 1 0.56 1.00 0.73 0.92 U39318 0.80 1.00 0.91 1

240383_at2, 3 U133-B 1 1.00 1.00 -- -- AI239832 0.40 1.00 0.76 1

200668_s_at2, 3 U133-A 1 1.00 1.00 -- -- BC003395 0.60 1.00 0.82 1

200667_at2, 3 U133-A 1 1.00 1.00 -- -- BF448062 0.60 1.00 0.82 1

200669_s_at2, 3 U133-A 2 1.00 0.73 -- -- NM_003340 0.60 1.00 0.82 1

240383_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

200668_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

200667_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

200669_s_at2 U133Plus2 2 1.00 0.73 -- -- -- -- -- -- --
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Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: AATGAATAAA

SOURCE GeneReport for Unigene cluster: Hs.518773

Expression variation in blood from EXPOLDB for UBE2D3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section


Orthologs for UBE2D3 gene from 5/16 species (see all 16 )
Organism Gene Locus Description Human
Similarity
NCBI accessions
chimpanzee
(Pan troglodytes)
UBE2D31   -- ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, more 99.55(n)
98.64(a)
461941  XM_517826.2  XP_517826.2 
cow
(Bos taurus)
LOC7813091   -- similar to Ubiquitin-conjugating enzyme E2D 3 (UBC4/5 more 97.73(n)
95.92(a)
781309  XM_001249440.1  XP_001249441.1 
rat
(Rattus norvegicus)
Ube2d31   -- ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, more 98.41(n)
100(a)
81920  NM_031237.1  NP_112516.1 
mouse
(Mus musculus)
Ube2d31, 5 35
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, more1, 5 98.41(n)1
100(a)1
661051  NM_025356.31  NP_079632.11 
 AA4149515  AI4505815  (see all 47)
zebrafish
(Danio rerio)
wufj13d012   -- wufj13d01 85.26(n) 335444  BC059548.1 
About this table        Species with no ortholog for UBE2D3

ENSEMBL Gene Tree for UBE2D3
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for UBE2D3 gene
UBE2D12  UBE2D42  UBE2D22  

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/379 NCBI SNPs in UBE2D3 are shown (see all 379 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 130)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 4 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
------------
rs2233831,2
A,C,F,H,O103970389(+) CTTACA/GTTTCT 3 -- int1 ng318Minor allele frequency- G:0.42MN EU EA WA NA 720
rs2233901,2
A,C,F,H,O103967932(+) GCACAG/AGACCG 9 -- int1 ng31 ut516Minor allele frequency- A:0.48NA EU EA 438
rs2233911,2
A,C,F,H103967359(+) AGGAAG/AGAAAT 9 -- int1 ut51 trp38Minor allele frequency- A:0.15EU EA WA 824
rs2233871,2
A,C,F,O103968654(+) TTATGG/CTGTGG 9 -- int1 ng315Minor allele frequency- C:0.48NA MN EA 496
rs2233881,2
A,C,F,O103968582(+) GCTCGA/GGCCGG 9 -- ng31 int15Minor allele frequency- G:0.48NA MN EA 498
rs2233851,2
C,F,H103969454(+) aaaatA/Gcgact 8 -- int1 ng314Minor allele frequency- G:0.43EU EA WA 410
--
rs2233841,2
A,C,F103970271(+) ATCCAA/TGCTTA 3 -- int1 ng313Minor allele frequency- T:0.39NA 120
rs131170521,2
C,F,H103968885(+) CGTCCG/CCCAAG 9 -- ng31 int18Minor allele frequency- C:0.16EU EA WA 830
rs2233891,2
C,F103968081(+) GAGGAG/AGATCA 9 -- int1 ng31 ut51 trp35Minor allele frequency- A:0.23MN EA NA 1820
--
rs2233861,2
C103969406(+) cagtgC/Tttctc 9 -- ng31 int10--------
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HapMap Linkage Disequilibrium images for UBE2D3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602963

(Possibly Related Articles in Doctor's Guide)
About This Section

  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

10/28 PubMed articles for UBE2D3 gene (see all 28 ):
(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 7323 HGNC: 12476 AceView: UBE2D3 Ensembl:ENSG00000109332 euGenes: HUgn7323
ECgene: UBE2D3 H-InvDB: UBE2D3
(According to HUGE)
About This Section

  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

NameDescription
ATLAS Chromosomes in Cancer entry for UBE2D3 Genetics and Cytogenetics in Oncology and Haematology
(Available from WIS Yeda, Salk, Tufts)
About This Section

  --
(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for UBE2D3:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for UBE2D3-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
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 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for UBE2D3 Antibodies for UBE2D3
 Explore super-pooled esiRNAs Proteins for UBE2D3
 Lentivirus-delivered shRNAs for UBE2D3 Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
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